A facile procedure for the synthesis of 3-（2′-amino-3′-cyano-4′-arylpyrid-6′-yl） coumarins are being reported starting from 3- acetylcoumarin, aromatic aldehydes and malononitrile. The reactions were carried out...A facile procedure for the synthesis of 3-（2′-amino-3′-cyano-4′-arylpyrid-6′-yl） coumarins are being reported starting from 3- acetylcoumarin, aromatic aldehydes and malononitrile. The reactions were carried out on microwave irradiation in good yield with short time and easy work-up. The structures of all the compounds have been confirmed on the basis of their analytical, IR, ^1H NMR, and mass spectral data.展开更多
3-[1′ (1′ H)-Substituent-pyrazol-5′-yl] benzo[5, 6] coumarins and3-(1′,2′-oxazol-5′-yl)benzo[5,6]coumarin were prepared via condensation of3-(2′-formyl-1′-chlorovinyl) benzo [5, 6] coumarin with hydrazine deri...3-[1′ (1′ H)-Substituent-pyrazol-5′-yl] benzo[5, 6] coumarins and3-(1′,2′-oxazol-5′-yl)benzo[5,6]coumarin were prepared via condensation of3-(2′-formyl-1′-chlorovinyl) benzo [5, 6] coumarin with hydrazine derivatives or hydroxylamine.Reaction of 3-[1′(1′ H)-pyrazol-5′-yl] benzo[5, 6] coumarin with alkyl halidcs, olefiniccompounds or acid chlorides are described.展开更多
基金the Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials for financial support(No.JSKC07041).
文摘A facile procedure for the synthesis of 3-（2′-amino-3′-cyano-4′-arylpyrid-6′-yl） coumarins are being reported starting from 3- acetylcoumarin, aromatic aldehydes and malononitrile. The reactions were carried out on microwave irradiation in good yield with short time and easy work-up. The structures of all the compounds have been confirmed on the basis of their analytical, IR, ^1H NMR, and mass spectral data.
文摘3-[1′ (1′ H)-Substituent-pyrazol-5′-yl] benzo[5, 6] coumarins and3-(1′,2′-oxazol-5′-yl)benzo[5,6]coumarin were prepared via condensation of3-(2′-formyl-1′-chlorovinyl) benzo [5, 6] coumarin with hydrazine derivatives or hydroxylamine.Reaction of 3-[1′(1′ H)-pyrazol-5′-yl] benzo[5, 6] coumarin with alkyl halidcs, olefiniccompounds or acid chlorides are described.
