FINITE ELEMENT NUMERICAL SIMULATION OF TEMPERATURE FIELD IN METAL PATTERN CASTING SYSTEM AND "REVERSE METHOD" OF DEFINING THE THERMAL PHYSICAL COEFFICIENT

With the technology support of virtual reality and ANSYS software, an example on the simulation of temperature distribution of casting system during the solidification process was provided, which took the latent heat of phase change, the conditions for convection, and the interface heat transfer coefficient into consideration. The result of ANSYS was found to agree well with the test data. This research offers an unorthodox way or ＂reverse method＂ of defining the relevant thermal physical coefficient.

LEAST-SQUARES METHOD-BASED FEATURE FITTING AND EXTRACTION IN REVERSE ENGINEERING

The main purpose of reverse engineering is to convert discrete data pointsinto piecewise smooth, continuous surface models. Before carrying out model reconstruction it issignificant to extract geometric features because the quality of modeling greatly depends on therepresentation of features. Some fitting techniques of natural quadric surfaces with least-squaresmethod are described. And these techniques can be directly used to extract quadric surfaces featuresduring the process of segmentation for point cloud.

The Inheritance and Application of Chinese Reverse Contrast Typeface Style

This paper discusses the inheritance and application of Chinese character reverse contrast typeface style.It begins by analyzing the visual features of Western reverse contrast typeface styles,with a focus on Caslon Italian and French Clarendon,providing a Western perspective reference for subsequent Chinese character reverse contrast typeface style designs.The paper then traces the origins of the Chinese reverse contrast style,from the calligraphy style"Lacquer Script"to the earliest printing type"フワンテール形",exploring the historical background and cultural significance of the Chinese reverse contrast style.In the methodology section of Chinese character reverse contrast typeface style design,the discussion is conducted from two dimensions:inheritance and application.In terms of inheritance,through an in-depth analysis of"Lacquer Script"and"フワンテール形"typeface style,the paper summarizes three basic theories for modern Chinese character reverse contrast typeface style design.In the application section,it examines in detail the two most influential recent typeface styles,"Ribaasu"and"Basic Artistic",outlining three directions of application:extreme horizontal stroke variations,exaggerated contrast,and diverse decorative strokes,showcasing new directions and possibilities for Chinese character reverse contrast typeface style design.This paper not only reviews the developmental history of the Chinese character reverse contrast typeface style but also analyzes the design methodology of Chinese character reverse contrast typeface style through specific case studies.

Preparation of CaP/pDNA nanoparticles by reverse micro-emulsion method: Optimization of formulation variables using experimental design

In this study, the CaP/pDNA nanoparticles were prepared using Triton X-100/Butanol/Cyclohexane/Water reverse microemulsion system. Optimization of preparation conditions was based on evaluation of particle size by Box–Behnken design method. The particle sizes of the optimized CaP/pDNA nanoparticles were found to be 60.23 ± 4.72 nm, polydispersity index was 0.252 and pDNA encapsulate efficiency was more than 90%. The optimized CaP/pDNA nanoparticles have pH sensitivity and biocompatibility. Further, optimized CaP/pDNA nanoparticles showed higher transfection efficiency.

Computational Fluid Dynamics(CFD) Analysis and Optimization of Reconstructed Intake System of Cylinder Head Based on Slicing Reverse Method

To find out and improve the flow characteristics inside the intake system of cylinder head,the application of computational fluid dynamics(CFD)in the evaluation and optimization of the reconstructed intake system based on slicing reverse method was proposed.The flow characteristics were found out through CFD,and the velocity vector field,pressure field and turbulent kinetic energy field for different valve lifts were discussed,which were in good agreement with experimental data,and the quality of reconstruction was evaluated.In order to improve its flow characteristic,an optimization plan was proposed.The results show that the flow characteristics after optimization are obviously improved.The results can provide a reference for the design and optimization of the intake system of cylinder head.

A Stability Indicating Reverse Phase-HPLC Method Development and Validation for the Estimation of Rucaparib in Bulk and Pharmaceutical Dosage Form

The research was carried out for establishing a new reverse phase-HPLC stability indicating method for the quantification of Rucaparib. The experiment was determined on Waters HPLC instrument using 996 photo-diode array detector. The separation was done by using symmetry C-18 ODS (25 cm × 0.46 cm internal diameter) 5 μm analytical column containing mobile phase of Phosphate buffer (0.02 M) and methanol [65:35% v/v] adjusted pH to 4.8 by adding dilute ortho phosphoric acid. The method was run at 1 ml·min-1 at 286 nm detection. The drug was eluted at 5.484 min. After developing the method, it was assured for the intended use by validation which was done according to ICH Q2B guidelines. The analytical parameters checked were linearity, accuracy, repeatability, intermediate precision, limit of detection, limit of quantitation, ruggedness and robustness. It was observed that the response of the detector was linear in the range of 6 - 14 μg/ml with correlation coefficient of 0.999. The results of all the parameters were found to be within the acceptance criteria. The stability indicating assay method was established by using the samples generated by forced degradation process. The forced degradation was carried out by subjecting the drug to acid, alkali, thermal, oxidative and photolytic degradation and the results showed that the degradation products were successfully separated from the drug. Hence, this can be applied perfectly later for the analysis of quality of the rucaparib drug.

A Stability Indicating Reverse Phase-HPLC Method Development and Validation for the Estimation of Bimatoprost 0.3% &Timolol 0.5% Pharmaceutical Ophthalmic Dosage Form

The research was carried out to establish a new reverse phase-HPLC stability indicating method for quantifying Bimatoprost & Timolol in ophthalmic solution. The experiment of Bimatoprost & Timolol in ophthalmic solution method development was determined on Waters HPLC instrument using a UV Detector. The separation was done by using L11, Zorbex SB phenyl (4.6 mm × 250 mm internal diameter) 5 μm analytical column, containing mobile phase of Phosphate buffer (0.02 M), methanol, and acetonitrile [50:30:20 % v/v]. The method was run at 1 ml·min-1 at 210 nm for Bimatoprost and 295 nm for Timolol for detection. The drug was eluted at 10.81 min for Bimatoprost and 3.77 min for Timolol. After developing the method, it was assured for the intended use by validation, which was done according to ICH Q2B guidelines. The analytical parameters checked were Specificity/Selectivity, linearity, Range, accuracy, ruggedness, and robustness. It was observed that the response of the detector was linear in the range of 6 - 18 μg/ml with a correlation coefficient of 0.999. The results of all the parameters were found to be within the acceptance criteria. The stability-indicating assay method was established by using the samples generated by the forced degradation process. The forced degradation was carried out by subjecting the drug to acid, alkali, thermal, oxidative, and photolytic degradation, and the results showed that the degradation products were successfully separated from the drug. Hence, this can be applied perfectly later for the quantitative analysis of Bimatoprost 0.3% + Timolol 0.5% Ophthalmic Solution drugs for pharmaceutical use. Currently, there is no official method for Bimatoprost & Timolol combination products in USP or BP. Available research work related to single Bimatoprost or Timolol products was not suitable for testing Bimatoprost and Timolol combination drugs. Additionally, there is no stability-indicating method to test Bimatoprost & Timolol combination products which insist us to do research and develop a new reverse phase-HPLC indicating method which will be faster and more accurate.

Efficient hybrid method for time reversal superresolution imaging

An efficient hybrid time reversal（TR） imaging method based on signal subspace and noise subspace is proposed for electromagnetic superresolution detecting and imaging. First, the locations of targets are estimated by the transmitting-mode decomposition of the TR operator（DORT） method employing the signal subspace. Then, the TR multiple signal classification（TR-MUSIC）method employing the noise subspace is used in the estimated target area to get the superresolution imaging of targets. Two examples with homogeneous and inhomogeneous background mediums are considered, respectively. The results show that the proposed hybrid method has advantages in CPU time and memory cost because of the combination of rough and fine imaging.

Stable attenuation-compensated reverse time migration and its application to land seismic data

Intrinsic attenuation of the earth causes energy loss and phase distortion in seismic wave propagation.To obtain high-resolution imaging results,these negative effects must be considered during reverse time migration(RTM).We can easily implement attenuation-compensated RTM using the constant Q viscoacoustic wave equation with decoupled amplitude attenuation and phase dispersion terms.However,the nonphysical amplitude-compensation process will inevitably amplify the high-frequency noise in the wavefield in an exponential form,causing the numerical simulation to become unstable.This is due to the fact that the amplitude of the compensation grows exponentially with frequency.In order to achieve stable attenuation-compensated RTM,we modify the analytic expression of the attenuation compensation extrapolation operator and make it only compensate for amplitude loss within the effective frequency band.Based on this modified analytic formula,we then derive an explicit time-space domain attenuation compensation extrapolation operator.Finally,the implementation procedure of stable attenuation-compensated RTM is presented.In addition to being simple to implement,the newly proposed attenuation-compensated extrapolation operator is superior to the conventional low-pass filter in suppressing random noise,which will further improve the imaging resolution.We use two synthetic and one land seismic datasets to verify the stability and effectiveness of the proposed attenuationcompensated RTM in improving imaging resolution in viscous media.

On the Effect of the Rotating Chamber Reverse Speed on the Mixing of SiC Ceramic Particles in a Dry Granulation Process

In order to control the accumulation of SiC ceramic particles on the wall of the rotating chamber in the frame of a dry granulation process,the effect of the wall reverse speed on the mixing process is investigated.In particular,an Euler-Euler two-phase flow model is used to analyze the dynamics of both SiC particles and air.The numerical results show that by setting a certain reverse rotating speed of the rotating chamber,the accumulation of SiC particles on the wall can be improved,i.e.,their direction of motion in proximity to the wall can be changed and particles can be forced to re-join the granulation process.Experimental tests conducted to verify the reliability of the numerical findings,demonstrate that when the reverse rotating speed of the rotating chamber is 4 r/min,the sphericity of SiC particles in the rotating chamber is the highest and the fluidity is the best possible one.

Attenuation-compensated reverse time migration of GPR data constrained by resistivity

The high-frequency electromagnetic waves of ground-penetrating radar(GPR)attenuate severely when propagated in an underground attenuating medium owing to the influence of resistivity,which remarkably decreases the resolution of reverse time migration(RTM).As an effective high-resolution imaging method,attenuation-compensated RTM(ACRTM)can eff ectively compensate for the energy loss caused by the attenuation related to media absorption under the influence of resistivity.Therefore,constructing an accurate resistivity-media model to compensate for the attenuation of electromagnetic wave energy is crucial for realizing the ACRTM imaging of GPR data.This study proposes a resistivity-constrained ACRTM imaging method for the imaging of GPR data by adding high-density resistivity detection along the GPR survey line and combining it with its resistivity inversion profile.The proposed method uses the inversion result of apparent resistivity data as the GPR RTM-resistivity model for imposing resistivity constraints.Moreover,the hybrid method involving image minimum entropy and RTM is used to estimate the medium velocity at the diff raction position,and combined with the distribution characteristics of the reflection in the GPR profile,a highly accurate velocity model is built to improve the imaging resolution of the ACRTM.The accuracy and eff ectiveness of the proposed method are verified using the ACRTM test of the GPR simulated data of a typical attenuating media model.On this basis,the GPR and apparent resistivity data were observed on a field survey line,and use the GPR resistivity-constrained ACRTM method to image the observed data.A comparison of the proposed method with the conventional ACRTM method shows that the proposed method has better imaging depth,stronger energy,and higher resolution,and the obtained results are more conducive for subsequent data analysis and interpretation.

ANALYSIS AND RESEARCH OF COMPUTER-AIDED MODEL OF HIP JOINT BASED ON REVERSE ENGINEERING

Former research work about the modeling of hip joint focus on the uppersegment of femoral, and assumes the acetabulum cup is sphere concave, and the acetabulum prosthesesis semisphere. A method of acquiring the point data on the surface of the hipbone using the reverseengineering technology is presented. After analyzing the acetabulum surface fitting error, arotation ellipsoid CAD model is applied to fit the acetabulum surface, and then optimizationtechnique is used to find the geometric parameters of the model. The fitting error between thesphere and rotation ellipsoid is compared and gets the result that the fitting error of rotationellipsoid is smaller than sphere, and the rotation ellipsoid can describe the shape of theacetabulum better.

Determinants of Long Acting Reversible Contraception Method Use among Mothers in Extended Postpartum Period, Durame Town, Southern Ethiopia: A Cross Sectional Community Based Survey

Background: After a live birth, there is much unsatisfied interest in, and unmet family planning need for contraception. Waiting at least for 24 months before attempting the next pregnancy was recommended to reduce the risk of adverse maternal, perinatal and infant outcomes. The purpose of this study was to assess the determinants of long acting reversible contraception method use among mothers in extended postpartum period in Durame Town, Southern Ethiopia. Methods: A community based cross sectional study was conducted in Durame Town, Southern Ethiopia in December, 2014. Systematic random sampling technique was employed to recruit a total 460 study participants. Structured and pretested questioner was used to collect the data. Descriptive statistics was employed to characterize the study population using frequencies and proportions. Bivariate logistic regression analysis was conducted to identify all possible factors affecting utilization of LARC method. Multivariable logistic regression model was developed to control the confounding variables. Adjusted Odds Ratio (AOR) with 95% Confidence Interval (CI) was computed in identifying the real factors associated with use of LARC methods. Results: In this study we found that the prevalence of LARC method use among mothers during their extended postpartum period was 36.7% (95%CI: 32.2, 41.0). The unmet family planning need of mothers in the extended postpartum period was 123 (27.9%). The odds of using LARC by literate mother were four fold higher than their counterpart illiterate mothers (AOR 4.09 95%CI: 1.68, 9.58, P value < 0.001). The odds of mother who had pervious experiences of using LARC were up to eight folds higher than mother never used LARC methods (AOR 7.84 95% CI: 3.78, 16.23, P value< 0.001). Mother who received counseling service on LARC methods during delivery was up to three times more likely to utilize the services than not counseled (AOR 3.29 95% CI: 1.53, 7.03, P value < 0.001). And odds of mothers who received counseling service on LARC during immediate postpartum period were up to five fold more likely to opt method than never got the counseling service (AOR 4.55 95 % CI: 1.94, 10.66, P value < 0.001). Conclusions: In the study area, about one third of mothers utilized LARC methods during their extended postpartum period. Another one third of mother had unmet need for family planning. Participant’s education, previous history of using LARC methods, receiving counseling services on LARC during delivery and immediate postpartum periods were found major determinant for LARC use. Educating women, providing counseling service on LARC methods during antenatal, delivery and postnatal were recommended.

Application of Reverse Micelles of Alkyl Glucosides to Synthesis of Silver Nanoparticles

Silver nanoparticles were prepared in reverse micelles of alkyl glucosides by the injection method. The TEM image showed that the obtained silver nanoparticles displayed a wide variety of shapes. The size of silver nanoparticles was strongly dependent upon the kind of reducing agents, and tended to slightly increase with an increase in reaction temperature. The size of silver nanoparticles was hardly dependent upon the molar ratio of water to surfactant and the alkyl chain length of surfactants. Silver nanoparticles having various shapes were obtained at high concentration by the solid-liquid extraction method. The resultant silver colloid could be preserved for at least one month without precipitation.

Residual impact of 17α-methyltestosterone and histopathological changes in sex-reversed Nile tilapia (Oreochromis niloticus)

Objective:To examine sex reversal both by oral and by immersion using 17α-methyltestosterone on the methyltestosterone residual concentration and the organ histopathology of tilapia fish.Methods:This study used oral and immersion treatment methods for sex reversal of tilapia fish and used normal fish as the control and each treatment was repeated 4 times.17α-methyltestosterone at dosages of 60 mg/kg feed and 0.5 mg/L were used for oral and immersion methods,respectively.In the first step,tilapia fry were reared at 100 L aquaria,with a density of 1 fish/L for 2 months.In the next step,male tilapias were reared at happa(net cage)of(2×1×1)m3 size in the controlled pond,with a density of 30 fish/happa for 3 months.The methyltestosterone residual concentrations were analyzed by one-way analysis of variance and Duncan's multiple range tests,while organ histopathology was analyzed by descriptive method.Results:Residual concentrations in the serum of methyltestosterone-treated fish were significantly lower than that in normal fish,especially in 4-and 5-month-old tilapias with averages of less than 5μg/L,while in normal fish was more than 5μg/L.In the flesh,methyltestosterone residual concentrations showed relatively no significant differences between the oral and immersion treatment groups and methyltestosterone-treated fish remained lower compared to normal fish,except in 5-month-old tilapia.Methyltestosterone-treated tilapia exhibited histopathological changes on gill,liver,kidneys,and intestine organs.Conclusions:Sex reversal either by oral or by immersion has methyltestosterone residual concentration,but does not exceed the limits(5μg/L or 5μg/kg)of synthetic steroid on the fish body,although methyltestosterone causes histopathological changes on gill,liver,kidneys,and intestine.

An Improved Preisach Distribution Function Identification Method Considering the Reversible Magnetization

This paper presents an identification method of the scalar Preisach model to consider the effect of reversible magnetization in the process of distribution function identification.By reconsidering the identification process by stripping the influence of reversible components from the measurement data,the Preisach distribution function is identified by the pure irreversible components.In this way,the simulation accuracy of both limiting hysteresis loops and the inner internal symmetrical small hysteresis loop is ensured.Furthermore,through a discrete Preisach plane with a hybrid discretization method,the irreversible magnetic flux density components are computed more efficiently through the improved Preisach model.Finally,the proposed method results are compared with the traditional method and the traditional method considering reversible magnetization and validated by the laboratory test for the B30P105 electrical steel by Epstein frame.

Numerical Algorithm for Polarity Reversal Electric Field and Its Application

Aim To analyze the transient speciality of nonlinear, anisotropic, AC+DC coupling electric field, and to compare the withstand voltage strength of different insulation structures. Methods The transient process of polarity reversal is analyzed, considering the anisotropic property of oil immersed press board, a new finite element model based on Galerkin method is presented and verified. The model developed is applied to calculate the electric field distribution in four typical winding end structures of the converter transformer. Results\ The whole ring structure possesses the best insulation characteristics. Conclusion\ By introducing reasonable insulation components, insulation strength with the same surrounding sizes can be improved more than 30%.

逆向思维引导下项目式理实融合教学在数控课程中的应用

针对我校数控专业教学模式陈旧,理论与实践一体化教学内容单一等问题,对数控技术加工教学进行优化。提出了以逆向思维引导下项目式理实融合教学,即逆向思维教学方法,将理论编程、计算辅助设计、仿真模拟、机床操作这几门课程融合在一起进行项目式模块化教学,既由一名双师型教师呈现基础化、智能化、立体化、真实化、融合的教学空间,充分调动学生的积极性,使学生对专业学习保持足够的关注。构建数控技术理实融合课堂教学,使学生适应现代化生产需求,以此推动我校数控技术教学的发展。

全逆作法深基坑钢筋安装工程施工技术研究

超深基坑现场施工阶段存在较多的问题,其中钢筋吊运、后置构件安装等难度较大,容易影响安装施工效果。文章结合实际工程案例提出了全新的逆作钢筋工程施工技术。该技术融合吊物孔与塔吊、电动葫芦多元吊运系统,采取后置构件悬挂式钢筋安装法。然而在应用该技术时,梁柱接头部位容易产生严重损坏问题,导致结构性能无法达到工程的标准,因此需要采取合理的解决方案以及施工措施,克服施工难题。

An efficient source wavefield reconstruction scheme using single boundary layer values for the spectral element method

In the adjoint-state method, the forward-propagated source wavefield and the backward-propagated receiver wavefield must be available simultaneously either for seismic imaging in migration or for gradient calculation in inversion. A feasible way to avoid the excessive storage demand is to reconstruct the source wavefield backward in time by storing the entire history of the wavefield in perfectly matched layers. In this paper, we make full use of the elementwise global property of the Laplace operator of the spectral element method (SEM) and propose an efficient source wavefield reconstruction method at the cost of storing the wavefield history only at single boundary layer nodes. Numerical experiments indicate that the accuracy of the proposed method is identical to that of the conventional method and is independent of the order of the Lagrange polynomials, the element type, and the temporal discretization method. In contrast, the memory-saving ratios of the conventional method versus our method is at least N when using either quadrilateral or hexahedron elements, respectively, where N is the order of the Lagrange polynomials used in the SEM. A higher memorysaving ratio is achieved with triangular elements versus quadrilaterals. The new method is applied to reverse time migration by considering the Marmousi model as a benchmark. Numerical results demonstrate that the method is able to provide the same result as the conventional method but with about 1/25 times lower storage demand. With the proposed wavefield reconstruction method, the storage demand is dramatically reduced;therefore, in-core memory storage is feasible even for large-scale three-dimensional adjoint inversion problems.