BACKGROUND Coronavirus disease 2019(COVID-19)severity is classified as asymptomatic,mild,moderate,severe,and critical.Mild cases account for a large percentage of cases in the epidemic and typically exhibit a favorabl...BACKGROUND Coronavirus disease 2019(COVID-19)severity is classified as asymptomatic,mild,moderate,severe,and critical.Mild cases account for a large percentage of cases in the epidemic and typically exhibit a favorable prognosis.However,a 49%-67%mortality is noted in critical cases.No COVID-19-specific drug has been reported to date,and symptomatic and optimal supportive care,including oxygenation,anti-coinfection treatments,and ventilation,represent the mainstay of treatment for this disease,especially in critical patients.CASE SUMMARY In the above-mentioned context,we share our experience with the treatment of one critical COVID-19 case and review the relevant literature.CONCLUSION Timely tracheal intubation,reasonable mechanical ventilation support,appropriate anti-infection treatment,and early anticoagulation and immunity support are key factors in the successful treatment of this case.展开更多
Background Pandemic influenza A （H1N1） emerged rapidly in China in May 2009. Preliminary comparisons with seasonal influenza suggest that pandemic 2009 influenza A （HIN1） disproportionately affects younger ages an...Background Pandemic influenza A （H1N1） emerged rapidly in China in May 2009. Preliminary comparisons with seasonal influenza suggest that pandemic 2009 influenza A （HIN1） disproportionately affects younger ages and causes generally mild disease. To characterize disease progress, comorbidities, and treatment outcomes among consecutive severe and critically ill patients in a hospital served as a reference center for the care of patients with HIN1 in Shanghai, China.Methods A retrospective study on 62 severe and critically ill patients with 2009 influenza A （H1N1） was conducted in Shanghai Public Health Clinical Center. Demographic data, symptoms, comorbidities, disease progression, treatments, and clinical outcomes were collected for analysis.展开更多
This paper deals with the blow-up phenomenon, particularly, the geometric blow-up mechanism, of classical solutions to the Cauchy problem for quasilinear hyperbolic systems in the critical case. We prove that it is st...This paper deals with the blow-up phenomenon, particularly, the geometric blow-up mechanism, of classical solutions to the Cauchy problem for quasilinear hyperbolic systems in the critical case. We prove that it is still the envelope of the same family of characteristics which yields the blowup of classical solutions to the Cauchy problem in the critical case.展开更多
In this paper, the authors consider the existence of periodic solutions for a kind of second neutral functional differential equation as follows：（x（t） - cx（t -τ）＂ = g（t, x（t - μ（t））） ＋ e（t）,in the cr...In this paper, the authors consider the existence of periodic solutions for a kind of second neutral functional differential equation as follows：（x（t） - cx（t -τ）＂ = g（t, x（t - μ（t））） ＋ e（t）,in the critical case ｜c｜ = 1. By employing Mawhin＇s continuation theorem and some analysis techniques, some new results are obtained.展开更多
基金Supported by the Health and Family Planning Commission of Shenzhen Municipality,No.SZLY2018024and Sanming Project of Medicine in Shenzhen,No.SZSM201512031.
文摘BACKGROUND Coronavirus disease 2019(COVID-19)severity is classified as asymptomatic,mild,moderate,severe,and critical.Mild cases account for a large percentage of cases in the epidemic and typically exhibit a favorable prognosis.However,a 49%-67%mortality is noted in critical cases.No COVID-19-specific drug has been reported to date,and symptomatic and optimal supportive care,including oxygenation,anti-coinfection treatments,and ventilation,represent the mainstay of treatment for this disease,especially in critical patients.CASE SUMMARY In the above-mentioned context,we share our experience with the treatment of one critical COVID-19 case and review the relevant literature.CONCLUSION Timely tracheal intubation,reasonable mechanical ventilation support,appropriate anti-infection treatment,and early anticoagulation and immunity support are key factors in the successful treatment of this case.
文摘Background Pandemic influenza A （H1N1） emerged rapidly in China in May 2009. Preliminary comparisons with seasonal influenza suggest that pandemic 2009 influenza A （HIN1） disproportionately affects younger ages and causes generally mild disease. To characterize disease progress, comorbidities, and treatment outcomes among consecutive severe and critically ill patients in a hospital served as a reference center for the care of patients with HIN1 in Shanghai, China.Methods A retrospective study on 62 severe and critically ill patients with 2009 influenza A （H1N1） was conducted in Shanghai Public Health Clinical Center. Demographic data, symptoms, comorbidities, disease progression, treatments, and clinical outcomes were collected for analysis.
基金Project supported by the Special Funds for Major State Basic Research Project of ChinaSpecialized Research Fund for the Doctoral Program of Higher Education (No. 20020246002).
文摘This paper deals with the blow-up phenomenon, particularly, the geometric blow-up mechanism, of classical solutions to the Cauchy problem for quasilinear hyperbolic systems in the critical case. We prove that it is still the envelope of the same family of characteristics which yields the blowup of classical solutions to the Cauchy problem in the critical case.
基金Supported by the National Natural Science Foundation(1987100510371006)+1 种基金the Natural Science Foundation of Auhui Province of China(0504601032005kj301ZD)
文摘In this paper, the authors consider the existence of periodic solutions for a kind of second neutral functional differential equation as follows：（x（t） - cx（t -τ）＂ = g（t, x（t - μ（t））） ＋ e（t）,in the critical case ｜c｜ = 1. By employing Mawhin＇s continuation theorem and some analysis techniques, some new results are obtained.
