Aromatic aldehydes undergo crossed-aldol condensation with ketones in the presence of catalytic amount of sulfamic acid (SA) to afford the corresponding α,β-unsaturated aldol products under solvent-free conditions...Aromatic aldehydes undergo crossed-aldol condensation with ketones in the presence of catalytic amount of sulfamic acid (SA) to afford the corresponding α,β-unsaturated aldol products under solvent-free conditions in good to high yields at 45-80 ℃.展开更多
We wish to report a mild and efficient Crossed-Aldol reaction for the synthesis of α, ?-bis(substituted-ben- zylidene)cycloalkanones in the presence of catalytic amounts of covalently anchored sulfonic acid onto sil-...We wish to report a mild and efficient Crossed-Aldol reaction for the synthesis of α, ?-bis(substituted-ben- zylidene)cycloalkanones in the presence of catalytic amounts of covalently anchored sulfonic acid onto sil- ica gel under heterogeneous and solvent-free conditions. The present methodology offers several advantages such as excellent yields, simple procedure and work up steps, short reaction times and easy recovery of the catalyst. We have also demonstrated that the catalyst can be reused successfully.展开更多
文摘Aromatic aldehydes undergo crossed-aldol condensation with ketones in the presence of catalytic amount of sulfamic acid (SA) to afford the corresponding α,β-unsaturated aldol products under solvent-free conditions in good to high yields at 45-80 ℃.
文摘We wish to report a mild and efficient Crossed-Aldol reaction for the synthesis of α, ?-bis(substituted-ben- zylidene)cycloalkanones in the presence of catalytic amounts of covalently anchored sulfonic acid onto sil- ica gel under heterogeneous and solvent-free conditions. The present methodology offers several advantages such as excellent yields, simple procedure and work up steps, short reaction times and easy recovery of the catalyst. We have also demonstrated that the catalyst can be reused successfully.