The dislocation evolution wassimulated by using positiveand negative parallelstraightedgedislocationsrandomly distributing on the primary slip planes astheinitialconditions. Thevein and wallstructuresof dynamicequilib...The dislocation evolution wassimulated by using positiveand negative parallelstraightedgedislocationsrandomly distributing on the primary slip planes astheinitialconditions. Thevein and wallstructuresof dynamicequilibrium have been obtained. Abig dipolestructure wasfound inthesimulation.展开更多
The first part of this report describes the data reduction of non-merohedrally twinned crystals measured on Bruker and Agilent area-detector diffractometers. The image frames of methyl-2-aminopyrazine-3-carboxylate we...The first part of this report describes the data reduction of non-merohedrally twinned crystals measured on Bruker and Agilent area-detector diffractometers. The image frames of methyl-2-aminopyrazine-3-carboxylate were processed with APEX2 to furnish a set of overlapping diffraction indices that were used for solution and refinement. CrysAlisPRO was used for processing the frames of bis（diethyldicarbamato）nickel, which exists in monoclinic and tetragonal polymorphs, and in untwinned and twinned forms. In the second part, the crystal structure of [（3-formyl-4- hydroxyphenyl）methyl]triphenylphosphanium chloride was refined through the ‘HKLF 5＇（based on a combined set of diffraction indices） and PLATON（based on one set of diffraction indices） routes to give identical outcomes because the amount of overlap of the twin domains is small. For the third part, in a proof-of-concept investigation, the diffraction pattern of untwinned and twinned 4-{（E）-（4-aminophenyl）diazenyl]phenylamine was recorded simultaneously in one run; the three domains could be indexed and the crystal structure satisfactorily refined. The refinement was identical to those derived from independent measurements; the crystal structure features two independent centrosymmetric molecules, one of which is ordered and the other whole-molecule-disordered. This two-in-one run opens up the possibility that two or more crystals having different atomic compositions can be measured simultaneously if their reciprocal lattices do not overlap significantly.展开更多
YCOB,a member of the new crystal family of ReCOB (ReCOB=ReCa 4O(BO 3) 3,Re=La 3+ ,Nd 3+ ,Sm 3+ ,Gd 3+ ,Er 3+ ,Y 3+ ),has received mo re and more attentions in recent few years,because of its excellent nonlinear op tic...YCOB,a member of the new crystal family of ReCOB (ReCOB=ReCa 4O(BO 3) 3,Re=La 3+ ,Nd 3+ ,Sm 3+ ,Gd 3+ ,Er 3+ ,Y 3+ ),has received mo re and more attentions in recent few years,because of its excellent nonlinear op tical (N LO) properties and a great promise as a laser host material.Unfortunately,liking most of nonlinear optical crystals,the laser induced damages were also created in the new crystal family when irradiated by ultraviolet laser.In this report we present our preliminary results of the investigation on the radiation induced damage in YCOB crystals.展开更多
Forty-four different animal biles obtained from both invertebrates and vertebrates(including human bile)have been used for centuries for a host of maladies in traditional Chinese medicine(TCM)beginning with dog,ox and...Forty-four different animal biles obtained from both invertebrates and vertebrates(including human bile)have been used for centuries for a host of maladies in traditional Chinese medicine(TCM)beginning with dog,ox and common carp biles approximately in the Zhou dynasty(c.1046-256 BCE).Overall,different animal biles were prescribed principally for the treatment of liver,biliary,skin(including burns),gynecological and heart diseases,as well as diseases of the eyes,ears,nose,mouth and throat.We present an informed opinion of the clinical efficacy of the medicinal uses of the different animal biles based on their presently known principal chemical components which are mostly steroidal detergent-like molecules and the membrane lipids such as unesterified cholesterol and mixed phosphatidylcholines and sometimes sphingomyelin,as well as containing lipopigments derived from heme principally bilirubin glucuronides.All of the available information on the ethnopharmacological uses of biles in TCM were collated from the rich collection of ancient Chinese books on materia medica held in libraries in China and United States and the composition of various animal biles was based on rigorous separatory and advanced chemical identification techniques published since the mid-20th century collected via library(Harvard’s Countway Library)and electronic searches(PubMed and Google Scholar).Our analysis of ethnomedical data and information on biliary chemistry shows that specific bile salts,as well as the common bile pigment bilirubin and its glucuronides plus the minor components of bile such as vitamins A,D,E,K,as well as melatonin(N-acetyl-5-methoxytryptamine)are salutary in improving liver function,dissolving gallstones,inhibiting bacterial and viral multiplication,promoting cardiac chronotropsim,as well as exhibiting anti-inflammatory,anti-pyretic,anti-oxidant,sedative,anti-convulsive,anti-allergic,anti-congestive,anti-diabetic and anti-spasmodic effects.Pig,wild boar and human biles diluted with alcohol were shown to form an artificial skin for burns and wounds one thousand years ago in the Tang dynasty(618-907 CE).Although various animal biles exhibit several generic effects in common,a number of biles appear to be advantageous for specific therapeutic indications.We attempt to understand these effects based on the pharmacology of individual components of bile as well as attempting to identify a variety of future research needs.展开更多
文摘The dislocation evolution wassimulated by using positiveand negative parallelstraightedgedislocationsrandomly distributing on the primary slip planes astheinitialconditions. Thevein and wallstructuresof dynamicequilibrium have been obtained. Abig dipolestructure wasfound inthesimulation.
文摘The first part of this report describes the data reduction of non-merohedrally twinned crystals measured on Bruker and Agilent area-detector diffractometers. The image frames of methyl-2-aminopyrazine-3-carboxylate were processed with APEX2 to furnish a set of overlapping diffraction indices that were used for solution and refinement. CrysAlisPRO was used for processing the frames of bis（diethyldicarbamato）nickel, which exists in monoclinic and tetragonal polymorphs, and in untwinned and twinned forms. In the second part, the crystal structure of [（3-formyl-4- hydroxyphenyl）methyl]triphenylphosphanium chloride was refined through the ‘HKLF 5＇（based on a combined set of diffraction indices） and PLATON（based on one set of diffraction indices） routes to give identical outcomes because the amount of overlap of the twin domains is small. For the third part, in a proof-of-concept investigation, the diffraction pattern of untwinned and twinned 4-{（E）-（4-aminophenyl）diazenyl]phenylamine was recorded simultaneously in one run; the three domains could be indexed and the crystal structure satisfactorily refined. The refinement was identical to those derived from independent measurements; the crystal structure features two independent centrosymmetric molecules, one of which is ordered and the other whole-molecule-disordered. This two-in-one run opens up the possibility that two or more crystals having different atomic compositions can be measured simultaneously if their reciprocal lattices do not overlap significantly.
文摘YCOB,a member of the new crystal family of ReCOB (ReCOB=ReCa 4O(BO 3) 3,Re=La 3+ ,Nd 3+ ,Sm 3+ ,Gd 3+ ,Er 3+ ,Y 3+ ),has received mo re and more attentions in recent few years,because of its excellent nonlinear op tical (N LO) properties and a great promise as a laser host material.Unfortunately,liking most of nonlinear optical crystals,the laser induced damages were also created in the new crystal family when irradiated by ultraviolet laser.In this report we present our preliminary results of the investigation on the radiation induced damage in YCOB crystals.
基金Supported by Grants DK54012,DK73917,to Wang DQ-HDK36588,DK34854,and DK73687,to Carey MCall from the National Institutes of Health(US Public Health Service)
文摘Forty-four different animal biles obtained from both invertebrates and vertebrates(including human bile)have been used for centuries for a host of maladies in traditional Chinese medicine(TCM)beginning with dog,ox and common carp biles approximately in the Zhou dynasty(c.1046-256 BCE).Overall,different animal biles were prescribed principally for the treatment of liver,biliary,skin(including burns),gynecological and heart diseases,as well as diseases of the eyes,ears,nose,mouth and throat.We present an informed opinion of the clinical efficacy of the medicinal uses of the different animal biles based on their presently known principal chemical components which are mostly steroidal detergent-like molecules and the membrane lipids such as unesterified cholesterol and mixed phosphatidylcholines and sometimes sphingomyelin,as well as containing lipopigments derived from heme principally bilirubin glucuronides.All of the available information on the ethnopharmacological uses of biles in TCM were collated from the rich collection of ancient Chinese books on materia medica held in libraries in China and United States and the composition of various animal biles was based on rigorous separatory and advanced chemical identification techniques published since the mid-20th century collected via library(Harvard’s Countway Library)and electronic searches(PubMed and Google Scholar).Our analysis of ethnomedical data and information on biliary chemistry shows that specific bile salts,as well as the common bile pigment bilirubin and its glucuronides plus the minor components of bile such as vitamins A,D,E,K,as well as melatonin(N-acetyl-5-methoxytryptamine)are salutary in improving liver function,dissolving gallstones,inhibiting bacterial and viral multiplication,promoting cardiac chronotropsim,as well as exhibiting anti-inflammatory,anti-pyretic,anti-oxidant,sedative,anti-convulsive,anti-allergic,anti-congestive,anti-diabetic and anti-spasmodic effects.Pig,wild boar and human biles diluted with alcohol were shown to form an artificial skin for burns and wounds one thousand years ago in the Tang dynasty(618-907 CE).Although various animal biles exhibit several generic effects in common,a number of biles appear to be advantageous for specific therapeutic indications.We attempt to understand these effects based on the pharmacology of individual components of bile as well as attempting to identify a variety of future research needs.
