3-（Diphenylphosphino）propanoic acid（L2） has proved to be an efficient ligand for the copper-catalyzed C–N coupling reactions.N-arylation of imidazoles with aryl iodides catalyzed by CuCl/L2 was smoothly carried o...3-（Diphenylphosphino）propanoic acid（L2） has proved to be an efficient ligand for the copper-catalyzed C–N coupling reactions.N-arylation of imidazoles with aryl iodides catalyzed by CuCl/L2 was smoothly carried out in DMSO at 100 8C with a yield up to 98%.N-arylation of 1H-pyrazole with aryl iodides and bromides catalyzed by Cu（OAc）2/L2 in 1 4-dioxane also gave the corresponding products with yields of40%–98%.展开更多
基金financial support of this work by the National Basic Research Program of China (973 Program, No. 2012CB722603)the Program for Changjiang Scholars and Innovative Research Team in University (No. IRT1161)+1 种基金the National Natural Science Foundation of China (No. 21103114)the Doctor Foundation of Xinjiang Bingtuan (No. 2012BB010)
文摘3-（Diphenylphosphino）propanoic acid（L2） has proved to be an efficient ligand for the copper-catalyzed C–N coupling reactions.N-arylation of imidazoles with aryl iodides catalyzed by CuCl/L2 was smoothly carried out in DMSO at 100 8C with a yield up to 98%.N-arylation of 1H-pyrazole with aryl iodides and bromides catalyzed by Cu（OAc）2/L2 in 1 4-dioxane also gave the corresponding products with yields of40%–98%.
