Surgical treatment for severe cubital tunnel syndrome with absent sensory nerve conduction

For severe cubital tunnel syndrome, patients with absent sensory nerve action potential tend to have more severe nerve damage than those without. Thus, it is speculated that such patients generally have a poor prognosis. How absent sensory nerve action potential affects surgical outcomes remains uncertain owing to a scarcity of reports and conflicting results. This retrospective study recruited one hundred and fourteen cases(88 patients with absent sensory nerve action potential and 26 patients with present sensory nerve action potential) undergoing either subcutaneous transposition or in situ decompression. The minimum follow-up was set at 2 years. Primary outcome measures of overall hand function included their McGowan grade, modified Bishop score, and Disabilities of the Arm, Shoulder, and Hand Questionnaire(DASH) score. For patients with absent sensory nerve action potential, 71 cases(80.7%) achieved at least one McGowan grade improvement, 76 hands(86.4%) got good or excellent results according to the Bishop score, and the average DASH score improved 49.5 points preoperatively to 13.1 points postoperatively. When compared with the present sensory nerve action potential group, they showed higher postoperative McGowan grades and DASH scores, but there was no statistical difference between the modified Bishop scores of the two groups. Following in situ decompression or subcutaneous transposition, great improvement in hand function was achieved for severe cubital tunnel syndrome patients with absent sensory nerve action potential. The functional outcomes after surgery for severe cubital tunnel syndrome are worse in patients with absent sensory nerve action potential than those without. This study was approved by the Ethical Committee of Huashan Hospital, Fudan University, China(approval No. 2017142).

Theoretical Discussion on Treatment of Cubital Tunnel Syndrome Based on Theory of Liver,Spleen and Kidney

Cubital tunnel syndrome is a disease in which ulnar nerve is compressed by its surrounding tissues,and its main clinical manifestations are pain,sensory disturbance and dyskinesia.Its incidence rate is the second highest among peripheral nerve entrapment diseases,and it is one of the common clinical diseases.The theory of liver,spleen and kidney can guide the treatment of cubital tunnel syndrome with traditional Chinese medicine and acupuncture.By discussing the traditional Chinese medicine(TCM)pathogenesis and treatment principles of cubital tunnel syndrome,it provides modern medical theoretical support for TCM treatment of cubital tunnel syndrome.

Efficacy comparison between anterior subcutaneous and submuscular transposition of ulnar nerve in treating moderate-severe cubital tunnel syndrome

OBJECTIVE:To explore the optimal surgery in treating moderate-severe cubital tunnel(CuTS) syndrome by comparing the clinical efficiency of decompression and anterior subcutaneous transposition of ulnar nerve and decompression and anterior submuscular transposition of ulnar nerve,and to provide a theoretical basis for the appropriate surgical programs in treating moderate-severe Cu TS.METHODS:47 consecutive cases of moderate-severe Cu TS were surgically treated in our department from January 2014 to January 2017.All patients were divided into two groups by the doctor in our department.21 Cu TS cases were treated with decompression and anterior subcutaneous transposition of ulnar nerve,and other 26 cases were treated with decompression and anterior submuscular transposition of ulnar nerve.All the patients were followed 1 month,3 months and 6 months after operation to evaluate the recovery degree of ulnar nerve function and the clinical efficiency of the two methods was compared.RESULTS:Clinical symptoms of two groups were significant alleviated.There was no significant statistical difference between two groups in the clinical efficiency.CONCLUSION:Completely releasing of nerve truck is the most important step in treating mediate-severe Cu TS.Theclinical results of the two methods are similar,but the anterior subcutaneous transposition of ulnar nerve is more easy to operate and can be widely used.

肘管扩大成形术联合黄芪桂枝五物汤对中重度CTS尺神经功能恢复的影响

目的 探究肘管扩大成形术联合黄芪桂枝五物汤对中重度肘管综合征(CTS)患者尺神经功能恢复的影响。方法 将CTS患者106例均分为联合组及手术组。两组均行肘管扩大成形术治疗,联合组采用联合黄芪桂枝五物汤治疗。比较两组术前术后血清学指标及尺神经运动传导速度,记录术前术后CTS功能评分、上肢功能测定量表(DASH)评分及不良反应发生情况。结果 与术前比较,两组术后白细胞介素-1β、肿瘤坏死因子-α、DASH评分、转化生长因子-β1、CTS功能评分均改善,且联合组较手术组改善更为明显(P<0.05)。两组中、重度患者术后尺神经运动传导速度较术前增加,且随着恢复时间呈递增,中度患者高于重度患者(P<0.05);术后各时间点联合组中重度术后尺神经运动传导速度均高于手术组(P<0.05)。联合组不良反应发生率低于手术组(P<0.05)。结论肘管扩大成形术联合黄芪桂枝五物汤可提升尺神经运动传导速度,降低预后不良反应发生率。

The Associated Risk Factors for Entrapment Neuropathy in the Upper Extremity: The Locomotive Syndrome and Health Outcome in Aizu Cohort Study (LOHAS)

Purpose: Although carpal tunnel syndrome (CTS) and cubital tunnel syndrome (CuTS) are the most common neuropathies in the upper extremities, there have been few studies describing the etiology and associated factors in the general population. The purpose of this study was to investigate and clarify the etiology and associated factors for CTS and CuTS in the Japanese general population. Methods: A total of 1875 participants, who participated in health checkups conducted in rural areas in Japan in 2010, were enrolled. The prevalence of CTS and CuTS was investigated. Logistic regression models were performed to examine the relationship between CTS and CuTS and correlated factors such as occupational status, smoking and alcohol preferences, and medical characteristics. Results: The overall prevalence of CTS and CuTS was 2.0% and 2.2%, respectively. With regards to CTS, female subjects showed 7.33-times higher risk of CTS compared with male subjects. In addition, hypertension was also at high risk of CTS (5.56-times higher in borderline and 4.55-times higher in definite hypertension compared with normal blood pressure). However, there were no significant associations between CuTS and age, gender, occupation, smoking and alcohol preferences, or metabolic factors. Conclusions: CTS was associated with female gender and hypertension, whereas there was no obvious risk factor contributing to the onset of CuTS.

Berrettini Anastomosis Iatrogenic Injury Relating to Carpel Tunnel Syndrome Case Study

Some diseases require medical mitigation following the diagnosis, and sometimes the situation means that the patient has to undertake strong medication. However, this medicine is designed pharmacodynamically to interact with other organs before they reach the intended organ. Some mitigation imposes challenges on the involved organ. While the main organ will be healed, some drugs’ footprints will be left out to other organs. These are called iatrogenic injuries. In the case of anastomosis, it requires the alteration of surgical methods or the origin of iatrogenic injury in the arm;thus, the knowledge of anastomosis is very important to the field of medical practice. In addition, carpal tunnel release becomes vital in curing carpal tunnel syndrome. The paper focuses on a case of a 42-year-old woman found to have a complication to her middle finger. This case becomes important for studying Berrettini anastomosis iatrogenic injury, which relates to carpal tunnel syndrome. The Berrettini branch is a complication that facilitates communication between the superficial ulnar and median nerve. The analysis also provides the electro-diagnostic evidence of Berrettini anastomosis on how it can give a position three-finger and thus contribute to a force explanation of the median neuropraxia. Lastly, the paper provides information on the implication of the Berrettini branch for surgical use. The implication of pictures in the digital era can be used to analyze the varied connection and length between the median nerve and ulnar section. It’s easy to locate the position of high risk of iatrogenic injury in the palm due to the consistent location of Berrettini communication branches. The precaution is that operations have to be conducted moderately for a clear vision as the carefully mitigated practice ensures protection from the destruction and injury of the surrounding structures.

Preliminary Study on the Lesion Location and Prognosis of Cubital Tunnel Syndrome by Motor Nerve Conduction Studies

Background：To study lesions＇ location and prognosis of cubital tunnel syndrome （CubTS） by routine motor nerve conduction studies （MNCSs） and short-segment nerve conduction studies （SSNCSs,inching test）.Methods：Thirty healthy subjects were included and 60 ulnar nerves were studied by inching studies for normal values.Sixty-six patients who diagnosed CubTS clinically were performed bilaterally by routine MNCSs and SSNCSs.Follow-up for 1-year,the information of brief complaints,clinical symptoms,and physical examination were collected.Results：Sixty-six patients were included,88 of nerves was abnormal by MNCS,while 105 was abnormal by the inching studies.Medial epicondyle to 2 cm above medial epicondyle is the most common segment to be detected abnormally （59.09％）,P ＜ 0.01.Twenty-two patients were followed-up,17 patients＇ symptoms were improved.Most of the patients were treated with drugs and modification of bad habits.Conclusions：（1） SSNCSs can detect lesions of compressive neuropathy in CubTS more precisely than the routine motor conduction studies.（2） SSNCSs can diagnose CubTS more sensitively than routine motor conduction studies.（3） In this study,we found that medial epicondyle to 2 cm above the medial epicondyle is the most vulnerable place that the ulnar nerve compressed.（4） The patients had a better prognosis who were abnormal in motor nerve conduction time only,but not amplitude in compressed lesions than those who were abnormal both in velocity and amplitude.Our study suggests that SSNCSs is a practical method in detecting ulnar nerve compressed neuropathy,and sensitive in diagnosing CubTS.The compound muscle action potentials by SSNCSs may predict prognosis of CubTS.

Pathogenesis and electrodiagnosis of cubital tunnel syndrome

Background Cubital tunnel syndrome is a well-recognized clinical condition and is the second most common peripheral compression neuropathy. This study was designed to investigate the causes of cubital tunnel syndrome by surgical means and to assess the clinical value of the neurophysiological diagnosis of cubital tunnel syndrome. Methods Twenty-one patients (involving a total of 22 limbs from 16 men and 5 women, aged 22 to 63, with a mean age of 49 years) with clinical symptoms and signs indicating a problem with their ulnar nerve underwent motor conduction velocity examinations at different sites along the ulnar nerve and examinations of sensory conduction velocity in the hand, before undergoing anterior transposition of the ulnar nerve.Results Electromyographic abnormalities were seen in 21 of 22 limbs [motor nerve conduction velocity (MCV) range (15.9-47.5) m/s, mean 32.7 m/s] who underwent motor conduction velocity examinations across the elbow segment of the ulnar nerve. Reduced velocity was observed in 13 of 22 limbs [MCV (15.7-59.6) m/s, mean 40.4 m/s] undergoing MCV tests in the forearms. An absent or abnormal sensory nerve action potential following stimulation was detected in the little finger of 14 of 22 limbs. The factors responsible for ulnar compression based on observations made during surgery were as follows: 15 cases involved compression by arcuate ligaments, muscle tendons, or bone hyperplasia; 2 involved fibrous adhesion; 3 involved compression by the venous plexus or a concurrent thick vein; 2 involved compression by cysts. Conclusions Factors inducing cubital tunnel syndrome include both common factors that have been reported and rare factors, involving the venous plexus, thick veins, and cysts. Tests of motor conduction velocity at different sites along the ulnar nerve should be helpful in diagnosis cubital tunnel syndrome, especially MCV tests indicating decreased velocity across the elbow segment of the ulnar nerve.

Effect of Elbow Position on Short-segment Nerve Conduction Study in Cubital Tunnel Syndrome

Background： The appropriate elbow position of short-segment nerve conduction study （SSNCS） to diagnose cubital tunnel syndrome （CubTS） is still controversial. The goal of this study was to determine the effect of different elbow positions at full extension and 70° flexion on SSNCS in CubTS. Methods： In this cross-sectional study, the clinical data of seventy elbows from 59 CubTS patients between September, 2011 and December, 2014 in the Peking University First Hospital were included as CubTS group. Moreover, thirty healthy volunteers were included as the healthy group. SSNCS were conducted in all subjects at elbow fhll extension and 70° elbow flexion. Paired nonparametric test, bivariate correlation, Bland-Altman, and Chi-squared test analysis were used to compare the effectiveness of elbow full extension and 70° flexion elbow positions on SSNCS in CubTS patients. Results： Data of upper limit was calculated from healthy group, and abnormal latency was judged accordingly. CubTS group＇s latency and compound muscle action potential （CMAP） of each segment at 70° elbow flexion by SSNCS was compared with lull extension position, no statistically significant difference were found （all P 〉 0.05）. Latency and CMAP of each segment at elbow full extension and 70° flexion were correlated （all P 〈 0 elbow （P - 0.43）, and the latency （P = 0.15） and the CMAP （P = 01）, except the latency of segment of 4 cm to 6 cm above 0.06） of segment of 2 cm to 4 cm below elbow. Bivariate correlation and Bland-Altman analysis proved the correlation between elbow full extension and 70° flexion. Especially in segments across the elbow （2 cm above the elbow and 2 cm below it）, latency at elbow full extension and 70° flexion were strong direct associated（r=0.83, P〈0.01;r=0.55, P〈0.01）,andsodidtheCMAP（r 0.49, P〈0.01;r=0.72, P〈0.01）.Therewasno statistically significant difference in abnormality of each segment at full extension as measured by SSNCS compared with that at 70° flexion （P 〉 0.05, respectively）. Conclusions： There was no statistically significant difference in the diagnosis of CubTS with the elbow at full extension compared with that at 70° flexion during SSNCS. We suggest that elbow positon at full extension can also be used during SSNCS.

高频多普勒超声诊断肘管综合征和腕管综合征的临床价值

目的 :探讨高频多普勒超声(High-frequency Doppler ultrasound,HFU)在肘管综合征(Cubital tunnel syndrome,CuTS)和腕管综合征(Carpal tunnel syndrome,CTS)诊断和病因检测中的临床价值。方法 :选择2021年1-12月在我院就诊的CTS(n=46例)、CuTS(n=41例)患者作为研究对象,所有患者均行HFU检查,观察健侧和患侧HFU检查结果 、HFU诊断CuTS和CTS的临床价值、HFU预测CuTS和CTS病因与手术结果的一致性。结果:41例CuTS患者患侧尺神经卡处直径和横截面面积(CSA)均低于健侧相应位置,差异有统计学意义(P<0.05);患侧尺神经肿胀处直径、CSA、面积肿胀率、厚度肿胀率均高于健侧相应位置,差异有统计学意义(P<0.05)。CTS患者患侧正中神经腕管入口处前后径、左右径和CSA均高于健侧相应位置,差异有统计学意义(P<0.05)。尺神经肿胀处CSA预测CuTS的曲线下面积(AUC)最高。正中神经腕管入口处CSA预测CTS的AUC高于前后径和左右径。HFU检测CuTS病因中滑膜瘤、骨赘结缔组织增生、肿大淋巴结、关节腔滑膜炎结果与手术结果完全一致(P=0.000),肘管中囊肿、关节腔积液与手术结果高度相关(P<0.001)。HFU检测CTS病因与手术结果完全一致(P=0.000)。结论:HFU在CuTS和CTS诊断和病因检测中均具有重要价值,值得临床推广应用。

肘管综合征术后翻修疗效评估

目的探讨肘管综合征翻修的原因,总结肘管综合征翻修术中的细节并评估疗效,降低该病的翻修率。方法对2019年4月至2022年8月我院收治的14例肘管综合征翻修患者资料进行分析,观察初次手术后尺神经的张力、形态、卡压部位是否解除及术后疗效,对比翻修术后症状改善情况,总结翻修原因并评估翻修术疗效。结果初次手术疗效不佳,术后3个月内无改善或症状持续加重者需行翻修术。翻修的主要原因是手术切口设计不规范(14/14),次要原因为未全程松解尺神经卡压点(12/14),少见原因为术区止血不确切(1/14)及对感觉神经保护不足(1/14)。根据顾氏肘管综合征功能评定标准,翻修术优良率为9/14。结论肘管综合征术后翻修的主要原因是手术细节的处理不当,术中规范化操作可降低翻修率,初次手术失败后翻修术仍是有效的。

关节镜联合肘管扩大成型术治疗肘关节骨性关节炎伴肘管综合征疗效观察

目的探讨关节镜联合肘管扩大成型术治疗肘关节骨性关节炎伴肘管综合征的临床疗效。方法选择2020年9月至2023年8月河北省沧州中西医结合医院骨外科收治的101例肘关节骨性关节炎伴肘管综合征患者为研究对象,按照手术方式不同将患者分为观察组(n=51)和对照组(n=50)。观察组患者采用关节镜联合肘管扩大成型术,对照组患者采用常规肘管扩大成型术。观察并记录2组患者的手术时间、术中出血量、住院时间、并发症发生情况。分别于术前、术后6个月时,采用Mayo肘关节功能评分(MEPS)评估2组患者的肘关节功能,采用日常生活活动能力评定表(ADL)评估2组患者的日常生活能力,采用视觉模拟评分(VAS)评估2组患者的疼痛程度;使用关节量角器测量肘关节旋前度数、旋后度数、屈伸度数,评估2组患者的肘关节活动度;使用Keypoint型肌电图仪检测小指展肌的复合肌肉动作电位(CMAP)、尺神经的神经传导速度(NCV)、运动诱发电位潜伏期(MEPLP),评估2组患者神经恢复情况。结果观察组患者的手术时间、住院时间显著短于对照组,术中出血量、并发症显著少于对照组(P<0.05)。术前,观察组和对照组患者的MEPS、ADL、VAS评分比较差异无统计学意义(P>0.05);术后6个月,观察组患者的MEPS、ADL评分显著高于对照组,VAS评分显著低于对照组(P<0.05)。术前,观察组和对照组患者的旋前度数、旋后度数、屈伸度数比较差异无统计学意义(P>0.05);术后6个月,2组患者的旋前度数、旋后度数、屈伸度数显著高于术前(P<0.05),观察组和对照组患者的旋前度数、旋后度数、屈伸度数比较差异无统计学意义(P>0.05)。术前,观察组和对照组患者的CMAP、NCV、MEPLP比较差异无统计学意义(P>0.05);术后6个月,观察组患者的CMAP、NCV显著高于对照组,MEPLP显著低于对照组(P<0.05)。结论常规肘管扩大成型术、关节镜联合肘关节扩大成型术均可改善肘关节骨性关节炎伴肘管综合征患者的肘关节活动度,但后者损伤更小,恢复更快,在提升肘关节功能及日常生活能力、减轻疼痛程度、调节肌电图检查指标等方面效果更佳,且并发症更少。

3D打印精准定位指导尺神经沟成形治疗肘管综合征

背景:随着肘管综合征患者增多,尺神经沟成形术不影响尺神经的正常解剖结构及走行,是治疗肘管综合征的主要外科手术之一。3D打印结合尺神经沟成形可以更精准地定位神经沟的拓展深度及宽度,从而避免一些手术并发症。目的:探讨3D打印技术结合尺神经沟成形对肘管综合征患者神经电生理及预后的影响。方法:选择2020年3月至2022年3月就诊于沧州市中西医结合医院的70例中重度肘管综合征患者作为研究对象,随机分为2组,每组35例,对照组行传统尺神经沟成形术,观察组行3D打印技术结合尺神经沟成形术,随访3个月。比较两组患者的临床疗效优良率,患肢拇短展肌复合肌肉动作电位潜伏期、波幅及尺神经运动传导速度,患侧握力、示中指和拇示指捏力、小指S-W单丝触觉、小指两点分辨觉及上肢功能障碍评定量表评分。结果与结论:①与对照组(74%)比较,观察组的疗效优良率(91%)显著升高(P<0.05);②与治疗前比较,治疗后两组患肢拇短展肌复合肌肉动作电位潜伏期显著缩短,波幅及尺神经运动传导速度显著升高;观察组潜伏期显著短于对照组,波幅及尺神经运动传导速度显著高于对照组(P<0.05);③与治疗前比较,治疗后两组患侧握力、示中指和拇示指捏力显著增大,小指S-W单丝触觉、小指两点分辨觉显著降低;观察组患侧握力、示中指和拇示指捏力显著大于对照组,小指S-W单丝触觉、小指两点分辨觉显著小于对照组(P<0.05);④与治疗前比较,治疗后两组上肢功能障碍评定量表评分显著降低,观察组显著低于对照组(P<0.05);⑤提示3D打印技术结合尺神经沟成形治疗肘管综合征,能够有效提高患者的临床疗效,促进其神经电生理恢复,改善手指和上肢功能,具有较高的临床应用价值。

Osborne韧带悬吊尺神经前置术在肘管综合征治疗中的应用及预后影响因素分析

目的 探究Osborne韧带悬吊尺神经前置术在肘管综合征治疗中的应用,并对影响患者预后的因素进行分析。方法 前瞻性选取2020年9月至2022年8月在秦皇岛市第一医院进行治疗的102例肘管综合征患者,采用信封法将患者分组:对照组(n=51)和研究组(n=51)。对照组行传统手术治疗,研究组行Osborne韧带悬吊尺神经前置术治疗。比较两组患者的治疗效果,记录手术前、手术后6个月患者的肌电指标[患侧尺神经传导速度(NCV)、患侧小指展肌复合肌肉动作电位波幅(CMAP)、运动电位潜伏期(MEPLP)]、疼痛程度[(VAS)评分]、现时痛强度(PPI)评分、上肢功能障碍测定量表(DASH)评分,并探究影响患者预后情况的因素。结果 研究组患者的有效率为96.08%,显著高于对照组(84.31%),差异有统计学意义(P<0.05)。研究组患者手术后6个月的NCV、CMAP分别为(50.77±3.98)m/s、(5.77±0.46)mV,高于对照组[(43.29±4.56)m/s、(4.12±0.39)mV];研究组MEPLP为(2.28±0.61)ms,低于对照组[(3.38±0.74)ms],差异均有统计学意义(P<0.05)。研究组患者手术后6个月的VAS评分、PPI评分、DASH评分均分别为(1.69±0.78)、(1.06±0.45)、(26.66±7.46)分,均低于对照组[(3.77±0.64)、(1.98±0.35)、(36.91±6.16)分],差异均有统计学意义(P<0.05)。102例患者经手术治疗,在随访期结束时,73例患者纳入预后良好组,29例纳入预后不良组。两组在肘部外伤史、病程方面比较,差异均无统计学意义(P>0.05),在年龄、性别、长期屈肘工作、肌肉萎缩、患病手与优势手为同侧、手部握力、是否采用Osborne韧带悬吊方面比较,差异均有统计学意义(P<0.05)。Logistic回归分析结果显示,肌肉萎缩及未采用Osborne韧带悬吊为影响患者预后不良的危险因素(P<0.05)。结论 采用Osborne韧带悬吊尺神经前置术对肘管综合征患者进行治疗可有效提高治疗有效率,改善患者的肌电图指标,缓解患者的疼痛程度,改善上肢功能障碍;此外,肌肉萎缩是影响患者预后不良的危险因素,可能会对患者的康复产生负面影响,应予以关注。

Recalcitrant cubital tunnel syndrome

Ulnar nerve neuropathy at the elbow represents the second most frequent compression neuropathy of the upper extremity.Of the five different anatomical areas responsible for ulnar nerve compression at the elbow region,the epitrochlear-olecranon channel and Osborne’s arcade are the most common.An additional cause of nerve damage is a dynamic process in which the ulnar nerve dislocates anteriorly at the epitrochlear-olecranon level during elbow flexion,partially or completely,causing nerve friction and constriction leading to chronic neuropathic pain.Failure after primary surgery is generally secondary to procedural errors or technical omissions,frequently represented by incomplete nerve decompression,failure to recognize nerve instability after nerve decompression,loosening of the nerve anchor after superficial nerve transposition with consequent spontaneous nerve relocation in the epitrochlear-olecranon channel,perineural fibrosis and neurodesis,which creates new nerve compression.In association with the clinical evaluation,electromyography studies,magnetic resonance imaging and ultrasound are useful tools that may aid in the decision-making process when considering revision surgery.Superficial anterior transposition is the most commonly employed technique but also has a high failure rate,as opposed to anterior deep transposition that is the method of choice for many surgeons despite being more technically demanding.The results of revision surgery following recalcitrant ulnar nerve compression at the elbow are inferior to those obtained after primary surgery.Nonetheless,the clinical advantages remain relevant provided that the revision surgery is performed by an expert surgeon.To avoid misinterpretation,the patient is completely informed of the quality of results.

完全清醒技术在肘管综合征术中的应用

目的:探讨完全清醒无止血带局部止血麻醉技术在肘管综合征手术中的临床疗效。方法:选择2020年3月~2023年3月弋矶山医院采用完全清醒技术治疗肘管综合征患者21例,均为单侧,评估麻醉、术中和术后的疼痛和焦虑情况及术中出血情况,术后观察麻醉不良反应和术区皮肤愈合情况,采用顾玉东肘管综合征评定标准对功能恢复进行评价。结果:21例患者均获得随访,随访时间151.0~425.0(264.00±71.88)d。术中患者无疼痛及焦虑,疼痛数字评分法(NRS)评分0分,术野清晰,无血肿及皮缘坏死等并发症。末次随访临床疗效优9例,良10例,可1例,差1例,总体优良率90.5%。结论:完全清醒技术治疗肘管综合征安全有效,方法可行。

超声引导下治疗周围神经卡压综合征的研究现状及应用前景

周围神经卡压综合征(PNES)是一种常见的慢性疾病,可以引起严重的疼痛和功能障碍。近年来,超声引导下治疗PNES的研究得到了越来越多的关注。目前的研究表明,超声引导下的注射技术可以显著减轻腕管综合征、肘管综合征等患者的疼痛和改善机体功能。这种治疗方法具有无创、安全、准确及可重复等优点,已被广泛应用于临床实践中。未来,随着超声技术和治疗方法的不断发展,超声引导下治疗PNES的应用前景将更加广阔。然而,目前仍需要进一步的研究以完善此类疗法的应用规范,证实临床效果和安全性。本文就超声引导下治疗PNES的研究现状及应用前景进行综述,旨在为临床治疗选择提供一定参考。

不同电生理检测方法在诊断肘管综合征中的应用价值

目的分析不同电生理检测方法在诊断肘管综合征(CuTS)中的应用价值。方法搜集2019年10月至2022年10月期间于南京中医药大学连云港附属医院临床诊断为CuTS的患者共45例(90个上肢)作为观察组,男31例,女14例,年龄26~81(51.3±13.1)岁;90个上肢根据有无CuTS临床症状分为有症状肢体组(50肢)和无症状肢体组(40肢)。并纳入同期健康志愿者30例(60个上肢)作为对照组,男20例,女10例,年龄28~79(50.3±11.6)岁。进行神经传导速度(NCV)、针极肌电图(EMG)、短段微移传导时间(SSCT)测定,比较两组相关参数差异。采用独立样本t检验和χ^(2)检验。结果与对照组比较,观察组尺神经运动神经传导速度(MNCV)在腕段-肘下段[(50.79±5.98)m/s比(59.15±5.15)m/s]、肘下段-肘上段[(48.07±7.14)m/s比(55.77±5.35)m/s]减慢,复合肌肉动作电位(CMAP)波幅在腕段[(9.16±4.18)mV比(13.91±4.25)mV]、肘下段5 cm[(7.63±3.59)mV比(13.46±3.92)mV]、肘上段5 cm[(8.27±3.73)mV比(13.02±3.70)mV]降低,差异均有统计学意义(均P<0.05)。无症状肢体组中NCV异常率为12.5%(5/40),与SSCT检测异常率[45.0%(18/40)]比较,差异有统计学意义(χ^(2)=10.313,P=0.001)。应用SSCT检测法卡压区域大多分布于肘上3 cm至肘下2 cm(共5 cm)的位置,占明确标记的96.9%,其中肘上1 cm卡压率最高。结论不同电生理检测方式对临床早期定位、定性诊断及治疗有重要的指导价值,其中SSCT是早期诊断CuTS、明确卡压位点的重要检测方式。

高分辨率超声检测尺神经直径在肘管综合征中的应用

目的:评价高分辨率超声在肘管综合征诊断及预后中的价值。方法:自2018年1月至2019年6月,采用尺神经松解并皮下前置术的方法治疗47例肘管综合征患者。男41例,女6例;年龄27~73岁;右侧31例,左侧15例,双侧1例。术前、术后应用高分辨率超声检测尺神经直径,术中直观下进行测量,以尺神经功能评定试行标准评估患者恢复状态,并调查患者满意度。结果:47例患者术后切口均为Ⅰ级愈合并全部获得随访,于出院后12个月进行随访。术前尺神经受压部位的直径(0.16±0.04)cm,术后为(0.23±0.04)cm。尺神经功能评定结果:优16例,良18例,可13例。术后12个月满意度结果:满意28例,一般10例,不满意9例。结论:高分辨率超声术前检查与术中直观测量一致,术后高分辨率超声检查结果与随访结果一致,高分辨率超声为肘管综合征诊治的有效辅助手段。

小切口尺神经松解前置术联合黄芪桂枝五物汤对术后尺神经功能恢复及血清神经生长因子表达的影响

目的探究小切口尺神经松解前置术联合黄芪桂枝五物汤对术后尺神经功能恢复及血清神经生长因子(nerve growth factor,NGF)表达的影响。方法选取2019年4月—2021年3月经该院骨科确诊为肘管综合征并拟行尺神原位松解术的104例为研究对象,根据随机数表法将其分为研究组及对照组,每组52例。两组均行小切口尺神经松解前置术,术后研究组联合使用黄芪桂枝五物汤治疗。检测并记录术前及术后4周血清NGF水平、患肢手握力、拇示指及中示指捏力、尺动脉肌电功能,上肢功能测定量表(disabilities of the arm,shoulder and hand,DASH)评分及术后总有效率。结果术后4周研究组尺神经传导速度、波幅指数及血清NGF水平均显著高于治疗前及对照组,潜伏期指数明显低于治疗前及对照组(P<0.05);术后4周研究组患手握力、拇示指捏力、中示捏力均显著高于术前及对照组,DASH评分明显低于术前及对照组(P<0.05);研究组总有效率98.08%(51/52)显著高于对照组84.62%(44/52)(P<0.05)。结论联合使用黄芪桂枝五物汤有助于尺神经松解前置术后尺神经功能恢复,可提高神经传导速度,有效改善手肌力和感觉功能,较单纯手术治疗效果更佳。