The binary decision diagrams (BDDs) can give canonical representation to Boolean functions; they have wide applications in the design and verification of digital systems. A new method based on cultural algorithms fo...The binary decision diagrams (BDDs) can give canonical representation to Boolean functions; they have wide applications in the design and verification of digital systems. A new method based on cultural algorithms for minimizing the size of BDDs is presented in this paper. First of all, the coding of an individual representing a BDDs is given, and the fitness of an individual is defined. The population is built by a set of the individuals. Second, the implementations based on cultural algorithms for the minimization of BDDs, i.e., the designs of belief space and population space, and the designs of acceptance function and influence function, are given in detail. Third, the fault detection approaches using BDDs for digital circuits are studied. A new method for the detection of crosstalk faults by using BDDs is presented. Experimental results on a number of digital circuits show that the BDDs with small number of nodes can be obtained by the method proposed in this paper, and all test vectors of a fault in digital circuits can also be produced.展开更多
Binary particle swarm optimization algorithm(BPSOA) has the excellent characters such as easy to implement and few set parameters.But it is tendentious to stick in the local optimal solutions and has slow convergence ...Binary particle swarm optimization algorithm(BPSOA) has the excellent characters such as easy to implement and few set parameters.But it is tendentious to stick in the local optimal solutions and has slow convergence rate when the problem is complex.Cultural algorithm(CA) can exploit knowledge extracted during the search to improve the performance of an evolutionary algorithm and show higher intelligence in treating complicated problems.So it is proposed that integrating binary particle swarm algorithm into cultural algorithm frame to develop a more efficient cultural binary particle swarm algorithm (CBPSOA) for fault feature selection.In CBPSOA,BPSOA is used as the population space of CA;the evolution of belief space adopts crossover,mutation and selection operations;the designs of acceptance function and influence function are improved according to the evolution character of BPSOA.The tests of optimizing functions show the proposed algorithm is valid and effective.Finally,CBPSOA is applied for fault feature selection.The simulations on Tennessee Eastman process (TEP) show the CBPSOA can perform better and more quickly converge than initial BPSOA.And with fault feature selection,more satisfied performance of fault diagnosis is obtained.展开更多
The Resolution on Several Major Issues for Strengthening Socialist Civic Ethics adopted by the Sixth Plenary Session of the Party’s 14th Congress states that "socialist ethics is a major feature of socialist soc...The Resolution on Several Major Issues for Strengthening Socialist Civic Ethics adopted by the Sixth Plenary Session of the Party’s 14th Congress states that "socialist ethics is a major feature of socialist society, a great goal and an important guarantee for the modernization drive.The promotion of socialist morality bears closely on the accomplishment of the grand trans-century plan and the prosperity and development of the socialist cause". To do a good job in enhancing socialist ethics is of great practical importance and profound historical significance to the great cause of building up socialism with its own Chinese characters in the country, to the implementation of the two fundamental changes, and to the enforcement of the development strategy of revitalizing China by science and education and this country’s sustainable develop-展开更多
Due to the intermittency and instability of Wind-Solar energy and easy compensation of hydropower, this study proposes a Wind-Solar-Hydro power optimal scheduling model. This model is aimed at maximizing the total sys...Due to the intermittency and instability of Wind-Solar energy and easy compensation of hydropower, this study proposes a Wind-Solar-Hydro power optimal scheduling model. This model is aimed at maximizing the total system power generation and the minimum ten-day joint output. To effectively optimize the multi-objective model, a new algorithm named non-dominated sorting culture differential evolution algorithm(NSCDE) is proposed. The feasibility of NSCDE was verified through several well-known benchmark problems. It was then applied to the Jinping Wind-Solar-Hydro complementary power generation system. The results demonstrate that NSCDE can provide decision makers a series of optimized scheduling schemes.展开更多
In order to investigate the effects of aconitine on [Ca2+] oscillation patterns in cultured myocytes of neonatal rats, fluorescent Ca2+ indicator Fluo-4 NW and laser scanning confocal micro- scope (LSCM) were used...In order to investigate the effects of aconitine on [Ca2+] oscillation patterns in cultured myocytes of neonatal rats, fluorescent Ca2+ indicator Fluo-4 NW and laser scanning confocal micro- scope (LSCM) were used to detect the real-time changes of [Ca2+] oscillation patterns in the cultured myocytes before and after aconitine (1.0 μmol/L) incubation or antiarrhythmic peptide (AAP) and aconitine co-incubation. The results showed under control conditions, [Ca2+] oscillations were irregu- lar but relatively stable, occasionally accompanied by small calcium sparks. After incubation of the cultures with aconitine, high frequency [Ca2+] oscillations emerged in both nuclear and cytoplasmic regions, whereas typical calcium sparks disappeared and the average [Ca2+] in the cytoplasm of the cardiomyocyte did not change significantly. In AAP-treated cultures, intracellular [Ca2+] oscillation also changed, with periodic frequency, increased amplitudes and prolonged duration of calcium sparks. These patterns were not altered significantly by subsequent aconitine incubation. The basal value of [Ca2+] in nuclear region was higher than that in the cytoplasmic region. In the presence or absence of drugs, the [Ca2+] oscillated synchronously in both the nuclear and cytoplasmic regions of the same cardiomyocyte. It was concluded that although oscillating strenuously at high frequency, the average [Ca2+] in the cytoplasm of cardiomyocyte did not change significantly after aconitine incuba- tion, compared to the controls. The observations indicate that aconitine induces the changes in [Ca2+] oscillation frequency other than the Ca2+ overload.展开更多
The development of an innova-tion-oriented culture is one of thefive objectives set by the ChineseAcademy of Sciences (CAS) for itsKnowledge Innovation Program(KIP). It falls in line with the call
The ability of tetrandrine (Tet), an alkaloid isolated from Radix Stephaniae Tetrandrae, to reduce cortical neuronal injury in cortical cultures derived from fetal rats was quantitatively assessed by examination of mo...The ability of tetrandrine (Tet), an alkaloid isolated from Radix Stephaniae Tetrandrae, to reduce cortical neuronal injury in cortical cultures derived from fetal rats was quantitatively assessed by examination of morphological changes and measurement of lactate dehydrogenase (LDH) released to the extracellular bathing media Cell cultures exposed to the excitatory amino acids (EAA) 50 μmol L 1 glutamate (Glu), 20 μmol L 1 N methyl D aspartate (NMDA), 300 μmol·L 1 β N oxalylamino L alanine (BMAA, NMDA receptor agonist) or 20 μmol·L 1 β N oxaly lamino L alanine (BOAA, non NMDA receptor agonist) for 24 h at 37℃ showed widespread neuronal injury Tet had little effect on the injury induced by 20 μmol·L 1 NMDA but 10 7 and 10 6 μmol·L 1 Tet did partially attenuate the neuronal degeneration, neuronal loss and LDH efflux resulting from prolonged exposures to 100 μmol·L 1 Glu, 300 μmol·L 1 BMAA and 20 μmol·L 1 BOAA respectively The ability of Tet to reduce the neuronal injury induced by prolonged exposure to EAA may contribute, at least in part, to the reduction of Ca 2+ influx through inhibiting the opening of voltagegated Ca 2+ channels Another mechanism that Tet might have a little inhibitory effect on NMDA receptor on neuronal membrane cannot be excluded, as BMAA has been considered to act as a weak NMDA receptor agonist展开更多
基金supported by Natural Science Foundation of Guangdong Provincial of China (No.7005833)
文摘The binary decision diagrams (BDDs) can give canonical representation to Boolean functions; they have wide applications in the design and verification of digital systems. A new method based on cultural algorithms for minimizing the size of BDDs is presented in this paper. First of all, the coding of an individual representing a BDDs is given, and the fitness of an individual is defined. The population is built by a set of the individuals. Second, the implementations based on cultural algorithms for the minimization of BDDs, i.e., the designs of belief space and population space, and the designs of acceptance function and influence function, are given in detail. Third, the fault detection approaches using BDDs for digital circuits are studied. A new method for the detection of crosstalk faults by using BDDs is presented. Experimental results on a number of digital circuits show that the BDDs with small number of nodes can be obtained by the method proposed in this paper, and all test vectors of a fault in digital circuits can also be produced.
基金National High Technology Research and Development Program of China(No.2007AA04Z171)
文摘Binary particle swarm optimization algorithm(BPSOA) has the excellent characters such as easy to implement and few set parameters.But it is tendentious to stick in the local optimal solutions and has slow convergence rate when the problem is complex.Cultural algorithm(CA) can exploit knowledge extracted during the search to improve the performance of an evolutionary algorithm and show higher intelligence in treating complicated problems.So it is proposed that integrating binary particle swarm algorithm into cultural algorithm frame to develop a more efficient cultural binary particle swarm algorithm (CBPSOA) for fault feature selection.In CBPSOA,BPSOA is used as the population space of CA;the evolution of belief space adopts crossover,mutation and selection operations;the designs of acceptance function and influence function are improved according to the evolution character of BPSOA.The tests of optimizing functions show the proposed algorithm is valid and effective.Finally,CBPSOA is applied for fault feature selection.The simulations on Tennessee Eastman process (TEP) show the CBPSOA can perform better and more quickly converge than initial BPSOA.And with fault feature selection,more satisfied performance of fault diagnosis is obtained.
文摘The Resolution on Several Major Issues for Strengthening Socialist Civic Ethics adopted by the Sixth Plenary Session of the Party’s 14th Congress states that "socialist ethics is a major feature of socialist society, a great goal and an important guarantee for the modernization drive.The promotion of socialist morality bears closely on the accomplishment of the grand trans-century plan and the prosperity and development of the socialist cause". To do a good job in enhancing socialist ethics is of great practical importance and profound historical significance to the great cause of building up socialism with its own Chinese characters in the country, to the implementation of the two fundamental changes, and to the enforcement of the development strategy of revitalizing China by science and education and this country’s sustainable develop-
基金supported by the National Key R&D Program of China (2016YFC0402209)the Major Research Plan of the National Natural Science Foundation of China (No. 91647114)
文摘Due to the intermittency and instability of Wind-Solar energy and easy compensation of hydropower, this study proposes a Wind-Solar-Hydro power optimal scheduling model. This model is aimed at maximizing the total system power generation and the minimum ten-day joint output. To effectively optimize the multi-objective model, a new algorithm named non-dominated sorting culture differential evolution algorithm(NSCDE) is proposed. The feasibility of NSCDE was verified through several well-known benchmark problems. It was then applied to the Jinping Wind-Solar-Hydro complementary power generation system. The results demonstrate that NSCDE can provide decision makers a series of optimized scheduling schemes.
文摘In order to investigate the effects of aconitine on [Ca2+] oscillation patterns in cultured myocytes of neonatal rats, fluorescent Ca2+ indicator Fluo-4 NW and laser scanning confocal micro- scope (LSCM) were used to detect the real-time changes of [Ca2+] oscillation patterns in the cultured myocytes before and after aconitine (1.0 μmol/L) incubation or antiarrhythmic peptide (AAP) and aconitine co-incubation. The results showed under control conditions, [Ca2+] oscillations were irregu- lar but relatively stable, occasionally accompanied by small calcium sparks. After incubation of the cultures with aconitine, high frequency [Ca2+] oscillations emerged in both nuclear and cytoplasmic regions, whereas typical calcium sparks disappeared and the average [Ca2+] in the cytoplasm of the cardiomyocyte did not change significantly. In AAP-treated cultures, intracellular [Ca2+] oscillation also changed, with periodic frequency, increased amplitudes and prolonged duration of calcium sparks. These patterns were not altered significantly by subsequent aconitine incubation. The basal value of [Ca2+] in nuclear region was higher than that in the cytoplasmic region. In the presence or absence of drugs, the [Ca2+] oscillated synchronously in both the nuclear and cytoplasmic regions of the same cardiomyocyte. It was concluded that although oscillating strenuously at high frequency, the average [Ca2+] in the cytoplasm of cardiomyocyte did not change significantly after aconitine incuba- tion, compared to the controls. The observations indicate that aconitine induces the changes in [Ca2+] oscillation frequency other than the Ca2+ overload.
文摘The development of an innova-tion-oriented culture is one of thefive objectives set by the ChineseAcademy of Sciences (CAS) for itsKnowledge Innovation Program(KIP). It falls in line with the call
文摘The ability of tetrandrine (Tet), an alkaloid isolated from Radix Stephaniae Tetrandrae, to reduce cortical neuronal injury in cortical cultures derived from fetal rats was quantitatively assessed by examination of morphological changes and measurement of lactate dehydrogenase (LDH) released to the extracellular bathing media Cell cultures exposed to the excitatory amino acids (EAA) 50 μmol L 1 glutamate (Glu), 20 μmol L 1 N methyl D aspartate (NMDA), 300 μmol·L 1 β N oxalylamino L alanine (BMAA, NMDA receptor agonist) or 20 μmol·L 1 β N oxaly lamino L alanine (BOAA, non NMDA receptor agonist) for 24 h at 37℃ showed widespread neuronal injury Tet had little effect on the injury induced by 20 μmol·L 1 NMDA but 10 7 and 10 6 μmol·L 1 Tet did partially attenuate the neuronal degeneration, neuronal loss and LDH efflux resulting from prolonged exposures to 100 μmol·L 1 Glu, 300 μmol·L 1 BMAA and 20 μmol·L 1 BOAA respectively The ability of Tet to reduce the neuronal injury induced by prolonged exposure to EAA may contribute, at least in part, to the reduction of Ca 2+ influx through inhibiting the opening of voltagegated Ca 2+ channels Another mechanism that Tet might have a little inhibitory effect on NMDA receptor on neuronal membrane cannot be excluded, as BMAA has been considered to act as a weak NMDA receptor agonist