Metabolic-associated fatty liver disease(MAFLD)is one of the most common chronic liver diseases worldwide.In recent years,the occurrence rate of MAFLD has been on the rise,mainly due to lifestyle changes,high-calorie ...Metabolic-associated fatty liver disease(MAFLD)is one of the most common chronic liver diseases worldwide.In recent years,the occurrence rate of MAFLD has been on the rise,mainly due to lifestyle changes,high-calorie diets,and imbalanced dietary structures,thereby posing a threat to human health and creating heavy social and economic burdens.With the development of 16S sequencing and integrated multi-omics analysis,the role of the gut microbiota(GM)and its metabolites in MAFLD has been further recognized.The GM plays a role in digestion,energy metabolism,vitamin synthesis,the prevention of pathogenic bacteria colonisation,and immunoregulation.The gut-liver axis is one of the vital links between the GM and the liver.Toxic substances in the intestine can enter the liver through the portal vascular system when the intestinal barrier is severely damaged.The liver also influences the GM in various ways,such as bile acid circulation.The gut-liver axis is essential in maintaining the body’s normal physiological state and plays a role in the onset and prognosis of many diseases,including MAFLD.This article reviews the status of the GM and MAFLD and summarizes the GM characteristics in MAFLD.The relationship between the GM and MAFLD is discussed in terms of bile acid circulation,energy metabolism,micronutrients,and signalling pathways.Current MAFLD treat ments targeting the GM are also listed.展开更多
With the increasingly deepened sustainable development concept in China, the logistics industry is undergoing transformation toward green logistic, requiring relevant logistics companies to fully strengthen green logi...With the increasingly deepened sustainable development concept in China, the logistics industry is undergoing transformation toward green logistic, requiring relevant logistics companies to fully strengthen green logistics management to accelerate the sustainable development of the logistics industry. This paper is focused on the analysis of green logistics management in the context of sustainable development. The meaning of green logistics management is firstly introduced, and then the importance of green logistics management is discussed. According to the current status of green logistics management, this paper proposes relevant management countermeasures, hoping to provide relevant personnel with certain reference.展开更多
基金Guangzhou Planned Project of Science and Technology,No.2023A04J0612。
文摘Metabolic-associated fatty liver disease(MAFLD)is one of the most common chronic liver diseases worldwide.In recent years,the occurrence rate of MAFLD has been on the rise,mainly due to lifestyle changes,high-calorie diets,and imbalanced dietary structures,thereby posing a threat to human health and creating heavy social and economic burdens.With the development of 16S sequencing and integrated multi-omics analysis,the role of the gut microbiota(GM)and its metabolites in MAFLD has been further recognized.The GM plays a role in digestion,energy metabolism,vitamin synthesis,the prevention of pathogenic bacteria colonisation,and immunoregulation.The gut-liver axis is one of the vital links between the GM and the liver.Toxic substances in the intestine can enter the liver through the portal vascular system when the intestinal barrier is severely damaged.The liver also influences the GM in various ways,such as bile acid circulation.The gut-liver axis is essential in maintaining the body’s normal physiological state and plays a role in the onset and prognosis of many diseases,including MAFLD.This article reviews the status of the GM and MAFLD and summarizes the GM characteristics in MAFLD.The relationship between the GM and MAFLD is discussed in terms of bile acid circulation,energy metabolism,micronutrients,and signalling pathways.Current MAFLD treat ments targeting the GM are also listed.
文摘With the increasingly deepened sustainable development concept in China, the logistics industry is undergoing transformation toward green logistic, requiring relevant logistics companies to fully strengthen green logistics management to accelerate the sustainable development of the logistics industry. This paper is focused on the analysis of green logistics management in the context of sustainable development. The meaning of green logistics management is firstly introduced, and then the importance of green logistics management is discussed. According to the current status of green logistics management, this paper proposes relevant management countermeasures, hoping to provide relevant personnel with certain reference.
