A new application of Sun ONE architecture — an online custom system for Knitted Sweaters is presented, which links sweater design, manufacturing and sales in different places to share information through the Internet...A new application of Sun ONE architecture — an online custom system for Knitted Sweaters is presented, which links sweater design, manufacturing and sales in different places to share information through the Internet.The framework and characteristics of J2EE and Sun ONE are analyzed. Having studied the requirements of the online custom system for knitted sweaters, the paper presents a detailed and original system design based on J2EE technology and Web Services. This paper also gives descriptions on how to assemble and deploy the whole system under the Sun ONE architecture.展开更多
Background:As the market demands change,SMEs(small and medium-sized enterprises)have long faced many design issues,including high costs,lengthy cycles,and insufficient innovation.These issues are especially noticeable...Background:As the market demands change,SMEs(small and medium-sized enterprises)have long faced many design issues,including high costs,lengthy cycles,and insufficient innovation.These issues are especially noticeable in the domain of cosmetic packaging design.Objective:To explore innovative product family modeling methods and configuration design processes to improve the efficiency of enterprise cosmetic packaging design and develop the design for mass customization.Methods:To accomplish this objective,the basic-element theory has been introduced and applied to the design and development system of the product family.Results:By examining the mapping relationships between the demand domain,functional domain,technology domain,and structure domain,four interrelated models have been developed,including the demand model,functional model,technology model,and structure model.Together,these models form the mechanism and methodology of product family modeling,specifically for cosmetic packaging design.Through an analysis of a case study on men’s cosmetic packaging design,the feasibility of the proposed product family modeling technology has been demonstrated in terms of customized cosmetic packaging design,and the design efficiency has been enhanced.Conclusion:The product family modeling technology employs a formalized element as a module configuration design language,permeating throughout the entire development cycle of cosmetic packaging design,thus facilitating a structured and modularized configuration design process for the product family system.The application of the basic-element principle in product family modeling technology contributes to the enrichment of the research field surrounding cosmetic packaging product family configuration design,while also providing valuable methods and references for enterprises aiming to elevate the efficiency of cosmetic packaging design for the mass customization product model.展开更多
Additive manufacturing(AM)has revolutionized the design and manufacturing of patient-specific,three-dimensional(3D),complex porous structures known as scaffolds for tissue engineering applications.The use of advanced ...Additive manufacturing(AM)has revolutionized the design and manufacturing of patient-specific,three-dimensional(3D),complex porous structures known as scaffolds for tissue engineering applications.The use of advanced image acquisition techniques,image processing,and computer-aided design methods has enabled the precise design and additive manufacturing of anatomically correct and patient-specific implants and scaffolds.However,these sophisticated techniques can be timeconsuming,labor-intensive,and expensive.Moreover,the necessary imaging and manufacturing equipment may not be readily available when urgent treatment is needed for trauma patients.In this study,a novel design and AM methods are proposed for the development of modular and customizable scaffold blocks that can be adapted to fit the bone defect area of a patient.These modular scaffold blocks can be combined to quickly form any patient-specific scaffold directly from two-dimensional(2D)medical images when the surgeon lacks access to a 3D printer or cannot wait for lengthy 3D imaging,modeling,and 3D printing during surgery.The proposed method begins with developing a bone surface-modeling algorithm that reconstructs a model of the patient’s bone from 2D medical image measurements without the need for expensive 3D medical imaging or segmentation.This algorithm can generate both patient-specific and average bone models.Additionally,a biomimetic continuous path planning method is developed for the additive manufacturing of scaffolds,allowing porous scaffold blocks with the desired biomechanical properties to be manufactured directly from 2D data or images.The algorithms are implemented,and the designed scaffold blocks are 3D printed using an extrusion-based AM process.Guidelines and instructions are also provided to assist surgeons in assembling scaffold blocks for the self-repair of patient-specific large bone defects.展开更多
Keratoconus is an ectatic condition characterized by gradual corneal thinning,corneal protrusion,progressive irregular astigmatism,corneal fibrosis,and visual impairment.The therapeutic options regarding improvement o...Keratoconus is an ectatic condition characterized by gradual corneal thinning,corneal protrusion,progressive irregular astigmatism,corneal fibrosis,and visual impairment.The therapeutic options regarding improvement of visual function include glasses or soft contact lenses correction for initial stages,gas-permeable rigid contact lenses,scleral lenses,implantation of intrastromal corneal ring or corneal transplants for most advanced stages.In keratoconus cases showing disease progression corneal collagen crosslinking(CXL)has been proven to be an effective,minimally invasive and safe procedure.CXL consists of a photochemical reaction of corneal collagen by riboflavin stimulation with ultraviolet A radiation,resulting in stromal crosslinks formation.The aim of this review is to carry out an examination of CXL methods based on theoretical basis and mathematical models,from the original Dresden protocol to the most recent developments in the technique,reporting the changes proposed in the last 15y and examining the advantages and disadvantages of the various treatment protocols.Finally,the limits of non-standardized methods and the perspectives offered by a customization of the treatment are highlighted.展开更多
In the digital era,retailers are keen to find out whether omni-channel retailing helps improve long-term firm performance.In this paper,we employ machine learning techniques on a large consumption data set in order to...In the digital era,retailers are keen to find out whether omni-channel retailing helps improve long-term firm performance.In this paper,we employ machine learning techniques on a large consumption data set in order to measure customer lifetime value(CLV)as the basis for determining long-term firm performance,and we provide an empirical analysis of the relationship between omni-channel retailing and CLV.The results suggest that omni-channel retailing may effectively enhance CLV.Further analysis reveals that this process is influenced by heterogeneous consumer requirements and that significant differences exist in the extent to which the omni-channel transition may influence CLV depending on consumer preferences for diversity of commodities,sensitivity to the cost of contract performance,and sensitivity to warehousing costs.Hence,retailers should provide consumers with a complete portfolio of goods and services based on target consumers’heterogeneous requirements in order to increase omni-channel efficiency.展开更多
The development of ethnic minority tourism is currently a hot topic in domestic tourism development.As an important component of Chinese civilization,the Manchu people have created brilliant culture in the long river ...The development of ethnic minority tourism is currently a hot topic in domestic tourism development.As an important component of Chinese civilization,the Manchu people have created brilliant culture in the long river of historical development.As the hometown of the Manchu people,Fushun has unique folk cultural tourism resources and a strong ethnic flavor.Nowadays,under the promotion of the rural revitalization strategy,the construction of new rural areas is constantly developing,and rural tourism is gradually becoming a new industry.Therefore,in the context of the increasingly prosperous rural tourism industry,it has become increasingly important to combine the ethnic customs of Manchu culture with rural tourism.Taking the ethnic customs and integrated development of rural tourism in Xinbin Manchu Autonomous County of Fushun City,Liaoning Province as the research object,this paper mainly sorts out the current situation and characteristics of rural tourism development in the region,systematically explores the problems in development and how to further optimize development,and proposes new models suitable for the development of folk tourism in Xinbin of Fushun,in order to achieve maximum economic and social benefits and provide a reference for promoting the development of tourism in the region.展开更多
End-user computing empowers non-developers to manage data and applications, enhancing collaboration and efficiency. Spreadsheets, a prime example of end-user programming environments widely used in business for data a...End-user computing empowers non-developers to manage data and applications, enhancing collaboration and efficiency. Spreadsheets, a prime example of end-user programming environments widely used in business for data analysis. However, Excel functionalities have limits compared to dedicated programming languages. This paper addresses this gap by proposing a prototype for integrating Python’s capabilities into Excel through on-premises desktop to build custom spreadsheet functions with Python. This approach overcomes potential latency issues associated with cloud-based solutions. This prototype utilizes Excel-DNA and IronPython. Excel-DNA allows creating custom Python functions that seamlessly integrate with Excel’s calculation engine. IronPython enables the execution of these Python (CSFs) directly within Excel. C# and VSTO add-ins form the core components, facilitating communication between Python and Excel. This approach empowers users with a potentially open-ended set of Python (CSFs) for tasks like mathematical calculations, statistical analysis, and even predictive modeling, all within the familiar Excel interface. This prototype demonstrates smooth integration, allowing users to call Python (CSFs) just like standard Excel functions. This research contributes to enhancing spreadsheet capabilities for end-user programmers by leveraging Python’s power within Excel. Future research could explore expanding data analysis capabilities by expanding the (CSFs) functions for complex calculations, statistical analysis, data manipulation, and even external library integration. The possibility of integrating machine learning models through the (CSFs) functions within the familiar Excel environment.展开更多
To effectively evaluate the fuzziness of the market environment in product planning,a customer requirements analysis method based on multiple preference information is proposed.Firstly,decision-makers use a preferred ...To effectively evaluate the fuzziness of the market environment in product planning,a customer requirements analysis method based on multiple preference information is proposed.Firstly,decision-makers use a preferred information form to evaluate the importance of each customer requirement.Secondly,a transfer function is employed to unify various forms of preference information into a fuzzy complementary judgment matrix.The ranking vector is then calculated using row and normalization methods,and the initial importance of customer requirements is obtained by aggregating the weights of decision members.Finally,the correction coefficients of initial importance and each demand are synthesized,and the importance of customer requirements is determined through normalization.The development example of the PE jaw crusher demonstrates the effectiveness and feasibility of the proposed method.展开更多
Customer churns remains a key focus in this research, using artificial intelligence-based technique of machine learning. Research is based on the feature-based analysis four main features were used that are selected o...Customer churns remains a key focus in this research, using artificial intelligence-based technique of machine learning. Research is based on the feature-based analysis four main features were used that are selected on the basis of our customer churn to deduct the meaning full analysis of the data set. Data-set is taken from the Kaggle that is about the fine food review having more than half a million records in it. This research remains on feature based analysis that is further concluded using confusion matrix. In this research we are using confusion matrix to conclude the customer churn results. Such specific analysis helps e-commerce business for real time growth in their specific products focusing more sales and to analyze which product is getting outage. Moreover, after applying the techniques, Support Vector Machine and K-Nearest Neighbour perform better than the random forest in this particular scenario. Using confusion matrix for obtaining the results three things are obtained that are precision, recall and accuracy. The result explains feature-based analysis on fine food reviews, Amazon at customer churn Support Vector Machine performed better as in overall comparison.展开更多
Blockchain technology is a shared database of logs of all consumer transactions which are registered on all machines on a network.Both transactions in the system are carried out by consensus processes and to preserve ...Blockchain technology is a shared database of logs of all consumer transactions which are registered on all machines on a network.Both transactions in the system are carried out by consensus processes and to preserve confidentiality all thefiles contained cannot be changed.Blockchain technology is the fundamental software behind digital currencies like Bitcoin,which is common in the marketplace.Cloud computing is a method of using a network of external machines to store,monitor,and process information,rather than using the local computer or a local personal computer.The software is currently facing multiple problems including lack of data protection,data instability,and reliability.This paper aims to give the highest security for multiple user environments in cloud for storing and accessing the data in blocks.The users who are legitimate are only allowed for storing and accessing the data as like a secured block chain approach.As like the Blockchain which does not require a centralized system for transactions,the proposed system is also independent on centralized network interface.The decentralized system is developed in such a way to avoid counterfeiting.The system enables the fabricator to spend less or null resources to perform the validations for its direct operated stores.This ensures the product fabricator to avoid the circulation of its duplicate products.The customer as an end-user is also ensured to have only the genuine products from the fabricator.The Fabricator(F),Merchant(M)and consumer(C)forms an interconnected triangular structure without allowing any counterfeiting agents in their secured cloud chain.The pro-posed approach provides the stability in the security system of the cloud using the chaining mechanism within different blocks at each node.It takes roughly 4.7,6.2,and 7.5 ms,respectively,to register each node in the proposed system for 5,10,and 15 nodes.The overall registration time for each scenario is 11.9,26.2,and 53.1 ms,despite the fact that each node’s registration time was greatest for 10 nodes.By looking at the data,it’s clear that the number of nodes is a func-tion of time.展开更多
This paper presents a Model-Based Design(MBD)approach for the design and control of a customized manipulator intended for drilling and position-ing of dental implants accurately with minimal human intervention.While p...This paper presents a Model-Based Design(MBD)approach for the design and control of a customized manipulator intended for drilling and position-ing of dental implants accurately with minimal human intervention.While performing an intra-oral surgery for a prolonged duration within a limited oral cavity,the tremor of dentist's hand is inevitable.As a result,wielding the drilling tool and inserting the dental implants safely in accurate position and orientation is highly challenging even for experienced dentists.Therefore,we introduce a customized manipulator that is designed ergonomically by taking in to account the dental chair specifications and anthropomorphic data such that it can be readily mounted onto the existing dental chair.The manipulator can be used to drill holes for dental inserts and position them with improved accuracy and safety.Further-more,a thorough multi-body motion analysis of the manipulator was carried out by creating a virtual prototype of the manipulator and simulating its controlled movements in various scenarios.The overall design was prepared and validated in simulation using Solid works,MATLAB and Simulink through Model Based Design(MBD)approach.The motion simulation results indicate that the manipulator could be built as a prototype readily.展开更多
By providing real-time updates of essential information, airports not only display and disseminate information but also help control the flow of traffic. In order to maximize available space, particularly in high traf...By providing real-time updates of essential information, airports not only display and disseminate information but also help control the flow of traffic. In order to maximize available space, particularly in high traffic areas, Airport Display Information Systems should be integrated into the overall design of the airport and their positioning should be carefully planned to deliver optimal results. Airport Display Information Systems can help airports maximize space, increase customer satisfaction, and generate new revenue opportunities. The technology is designed not only to comply with environmental regulations, but also to help airports keep budgets in check. This paper discusses airport display systems, their connections and interoperability with other systems and who the key airport users of these airport display systems are.展开更多
The purpose of this paper is to provide empirical evidence for the validity of the relationship between service-oriented manufacturing information system (SMIS) customization and performance from three aspects: data f...The purpose of this paper is to provide empirical evidence for the validity of the relationship between service-oriented manufacturing information system (SMIS) customization and performance from three aspects: data flexibility, process flexibility and system flexibility. We select some questionnaires from the third round of High-performance manufacturing (HPM) data to construct the construct, verify the reliability and validity of the construct, extract principal components, and analyze the mediating effect by using multiple chain linear regression and structural equation model. The results show that SMIS customization has a significant impact on its performance, and this effect works through its flexibility. More specifically, it is the multiple chain mediation effect composed of data flexibility, process flexibility and system flexibility. The importance of SMIS customization and flexibility to the organization is made clear, which helps practitioners understand the internal mechanism that affects SMIS performance, so as to use limited resources to improve system performance.展开更多
The following paper is a brief theoretical approach to the state of the art in relation to the new demands of society in the area of climate and weather-related services for health. Apart from the study of the impacts...The following paper is a brief theoretical approach to the state of the art in relation to the new demands of society in the area of climate and weather-related services for health. Apart from the study of the impacts of climate change on health which requires a longer consideration, a special emphasis is given to the area of weather-related services based on biometeorological forecasting. A new way of understanding the interaction between atmospheric factors and living organisms is presented and some biometeorological indexes already developed are shown. Customized biometeorological services must be constructed in the field of human health based on the ICTs development and the amount of climatic data available but new approaches and scientific methods are required to success in achieving this enterprise.展开更多
Customer churn may be a critical issue for banks. The extant literature on statistical and machine learning for customer churn focuses on the problem of correctly predicting that a customer is about to switch bank, wh...Customer churn may be a critical issue for banks. The extant literature on statistical and machine learning for customer churn focuses on the problem of correctly predicting that a customer is about to switch bank, while very rarely consid-ers the problem of generating personalized actions to improve the customer retention rate. However, these decisions are at least as critical as the correct identification of customers at risk. The decision of what actions to deliver to what customers is normally left to managers who can only rely upon their knowledge. By looking at the scientific literature on CRM and personalization, this research proposes a number of models which can be used to generate marketing ac-tions, and shows how to integrate them into a model embracing both the analytical prediction of customer churn and the generation of retention actions. The benefits and risks associated with each approach are discussed. The paper also describes a case of application of a predictive model of customer churn in a retail bank where the analysts have also generated a set of personalized actions to retain customers by using one of the approaches presented in the paper, namely by adapting a recommender system approach to the retention problem.展开更多
With a view to accelerating the construction and development of the free trade zones and the foreign trade business of enterprises within the said zones, and making entering or leaving the zones convenient for those e...With a view to accelerating the construction and development of the free trade zones and the foreign trade business of enterprises within the said zones, and making entering or leaving the zones convenient for those enterprises; the Customs shall in accordance with the newly promulgated regulations as stipulated in Supervising Measures of the Customs in Free Trade Zones require that consigness, consignors or their agents register for the record their car.展开更多
The profitability of the system product is decided on the sales of the product. Furthermore, a customer satisfaction for products quality and a price have a big influence on the sales of the product. It spends limited...The profitability of the system product is decided on the sales of the product. Furthermore, a customer satisfaction for products quality and a price have a big influence on the sales of the product. It spends limited financial resources effectively to raise the profitability of the system product, and it is necessary to realize the high quality product correspond to the customer needs as much as possible. There may be close relationship between cost of a product and an expense to implement the individual inherent attribute of system product. For the purpose of improvement of the customer satisfaction for quality of system product, the method of quantitative quality requirement and evaluation based on the ISO/IEC9126 quality model that includes six quality characteristics is widely recognized. However, independency among each quality characteristic has not been sure and the suitability of method for quality requirement of system product by using these six quality characteristics could not certified statistically. In the precedent study, introduced the requirements definition method for the quality of system product based on the system quality model defined in ISO/IEC9126 and proposed the effectiveness of it statistically. This study have measured the customer satisfaction for the system quality from the viewpoint of six quality characteristics quantitatively and confirmed the effectiveness of the technique to evaluate. In this study, we have confirmed the relationship between inherent attributes of the product and quantitative result of a measured value of total customer satisfaction from the view point of six quality characteristics statistically. This study performed the trial to clarify the relations with the inherent attributes that quantitative result of a measurement of the customer satisfaction based on six quality characteristics by the quality model of ISO/IEC9126. In addition, this study performed the development of the prediction model to estimate the total customer satisfaction for the system product from the view point of inherent attribute of the product. In this paper, we propose the effectiveness of application of the estimated prediction model and possibility of improvement of the total customer satisfaction of a system product.展开更多
Cancer cell membrane(CCM)derived nanotechnology functionalizes nanoparticles(NPs)to recognize homologous cells,exhibiting translational potential in accurate tumor therapy.However,these nanoplatforms are majorly gener...Cancer cell membrane(CCM)derived nanotechnology functionalizes nanoparticles(NPs)to recognize homologous cells,exhibiting translational potential in accurate tumor therapy.However,these nanoplatforms are majorly generated from fixed cell lines and are typically evaluated in cell line-derived subcutaneous-xenografts(CDX),ignoring the tumor heterogeneity and differentiation from inter-and intra-individuals and microenvironments between heterotopic-and orthotopic-tumors,limiting the therapeutic efficiency of such nanoplatforms.Herein,various biomimetic nanoplatforms(CCM-modified gold@Carbon,i.e.,Au@C-CCM)were fabricated by coating CCMs of head and neck squamous cell carcinoma(HNSCC)cell lines and patient-derived cells on the surface of Au@C NP.The generated Au@C-CCMs were evaluated on corresponding CDX,tongue orthotopic xenograft(TOX),immunecompetent primary and distant tumor models,and patient-derived xenograft(PDX)models.The Au@C-CCM generates a photothermal conversion efficiency up to 44.2% for primary HNSCC therapy and induced immunotherapy to inhibit metastasis via photothermal therapy-induced immunogenic cell death.The homologous CCM endowed the nanoplatforms with optimal targeting properties for the highest therapeutic efficiency,far above those with mismatched CCMs,resulting in distinct tumor ablation and tumor growth inhibition in all four models.This work reinforces the feasibility of biomimetic NPs combining modular designed CMs and functional cores for customized treatment of HNSCC,can be further extended to other malignant tumors therapy.展开更多
As the banking industry gradually steps into the digital era of Bank 4.0,business competition is becoming increasingly fierce,and banks are also facing the problem of massive customer churn.To better maintain their cu...As the banking industry gradually steps into the digital era of Bank 4.0,business competition is becoming increasingly fierce,and banks are also facing the problem of massive customer churn.To better maintain their customer resources,it is crucial for banks to accurately predict customers with a tendency to churn.Aiming at the typical binary classification problem like customer churn,this paper establishes an early-warning model for credit card customer churn.That is a dual search algorithm named GSAIBAS by incorporating Golden Sine Algorithm(GSA)and an Improved Beetle Antennae Search(IBAS)is proposed to optimize the parameters of the CatBoost algorithm,which forms the GSAIBAS-CatBoost model.Especially,considering that the BAS algorithm has simple parameters and is easy to fall into local optimum,the Sigmoid nonlinear convergence factor and the lane flight equation are introduced to adjust the fixed step size of beetle.Then this improved BAS algorithm with variable step size is fused with the GSA to form a GSAIBAS algorithm which can achieve dual optimization.Moreover,an empirical analysis is made according to the data set of credit card customers from Analyttica official platform.The empirical results show that the values of Area Under Curve(AUC)and recall of the proposedmodel in this paper reach 96.15%and 95.56%,respectively,which are significantly better than the other 9 common machine learning models.Compared with several existing optimization algorithms,GSAIBAS algorithm has higher precision in the parameter optimization for CatBoost.Combined with two other customer churn data sets on Kaggle data platform,it is further verified that the model proposed in this paper is also valid and feasible.展开更多
基金the key Project of Ministry of Education of China(No01083)
文摘A new application of Sun ONE architecture — an online custom system for Knitted Sweaters is presented, which links sweater design, manufacturing and sales in different places to share information through the Internet.The framework and characteristics of J2EE and Sun ONE are analyzed. Having studied the requirements of the online custom system for knitted sweaters, the paper presents a detailed and original system design based on J2EE technology and Web Services. This paper also gives descriptions on how to assemble and deploy the whole system under the Sun ONE architecture.
基金the Guangdong Planning Office of Philosophy and Social Science(Grant No.GD22XYS04).
文摘Background:As the market demands change,SMEs(small and medium-sized enterprises)have long faced many design issues,including high costs,lengthy cycles,and insufficient innovation.These issues are especially noticeable in the domain of cosmetic packaging design.Objective:To explore innovative product family modeling methods and configuration design processes to improve the efficiency of enterprise cosmetic packaging design and develop the design for mass customization.Methods:To accomplish this objective,the basic-element theory has been introduced and applied to the design and development system of the product family.Results:By examining the mapping relationships between the demand domain,functional domain,technology domain,and structure domain,four interrelated models have been developed,including the demand model,functional model,technology model,and structure model.Together,these models form the mechanism and methodology of product family modeling,specifically for cosmetic packaging design.Through an analysis of a case study on men’s cosmetic packaging design,the feasibility of the proposed product family modeling technology has been demonstrated in terms of customized cosmetic packaging design,and the design efficiency has been enhanced.Conclusion:The product family modeling technology employs a formalized element as a module configuration design language,permeating throughout the entire development cycle of cosmetic packaging design,thus facilitating a structured and modularized configuration design process for the product family system.The application of the basic-element principle in product family modeling technology contributes to the enrichment of the research field surrounding cosmetic packaging product family configuration design,while also providing valuable methods and references for enterprises aiming to elevate the efficiency of cosmetic packaging design for the mass customization product model.
文摘Additive manufacturing(AM)has revolutionized the design and manufacturing of patient-specific,three-dimensional(3D),complex porous structures known as scaffolds for tissue engineering applications.The use of advanced image acquisition techniques,image processing,and computer-aided design methods has enabled the precise design and additive manufacturing of anatomically correct and patient-specific implants and scaffolds.However,these sophisticated techniques can be timeconsuming,labor-intensive,and expensive.Moreover,the necessary imaging and manufacturing equipment may not be readily available when urgent treatment is needed for trauma patients.In this study,a novel design and AM methods are proposed for the development of modular and customizable scaffold blocks that can be adapted to fit the bone defect area of a patient.These modular scaffold blocks can be combined to quickly form any patient-specific scaffold directly from two-dimensional(2D)medical images when the surgeon lacks access to a 3D printer or cannot wait for lengthy 3D imaging,modeling,and 3D printing during surgery.The proposed method begins with developing a bone surface-modeling algorithm that reconstructs a model of the patient’s bone from 2D medical image measurements without the need for expensive 3D medical imaging or segmentation.This algorithm can generate both patient-specific and average bone models.Additionally,a biomimetic continuous path planning method is developed for the additive manufacturing of scaffolds,allowing porous scaffold blocks with the desired biomechanical properties to be manufactured directly from 2D data or images.The algorithms are implemented,and the designed scaffold blocks are 3D printed using an extrusion-based AM process.Guidelines and instructions are also provided to assist surgeons in assembling scaffold blocks for the self-repair of patient-specific large bone defects.
文摘Keratoconus is an ectatic condition characterized by gradual corneal thinning,corneal protrusion,progressive irregular astigmatism,corneal fibrosis,and visual impairment.The therapeutic options regarding improvement of visual function include glasses or soft contact lenses correction for initial stages,gas-permeable rigid contact lenses,scleral lenses,implantation of intrastromal corneal ring or corneal transplants for most advanced stages.In keratoconus cases showing disease progression corneal collagen crosslinking(CXL)has been proven to be an effective,minimally invasive and safe procedure.CXL consists of a photochemical reaction of corneal collagen by riboflavin stimulation with ultraviolet A radiation,resulting in stromal crosslinks formation.The aim of this review is to carry out an examination of CXL methods based on theoretical basis and mathematical models,from the original Dresden protocol to the most recent developments in the technique,reporting the changes proposed in the last 15y and examining the advantages and disadvantages of the various treatment protocols.Finally,the limits of non-standardized methods and the perspectives offered by a customization of the treatment are highlighted.
基金the National Social Science Foundation of China(NSSFC)“Study on the Digital Transition of China’s Retail Business”(Grant No.18BJY176).
文摘In the digital era,retailers are keen to find out whether omni-channel retailing helps improve long-term firm performance.In this paper,we employ machine learning techniques on a large consumption data set in order to measure customer lifetime value(CLV)as the basis for determining long-term firm performance,and we provide an empirical analysis of the relationship between omni-channel retailing and CLV.The results suggest that omni-channel retailing may effectively enhance CLV.Further analysis reveals that this process is influenced by heterogeneous consumer requirements and that significant differences exist in the extent to which the omni-channel transition may influence CLV depending on consumer preferences for diversity of commodities,sensitivity to the cost of contract performance,and sensitivity to warehousing costs.Hence,retailers should provide consumers with a complete portfolio of goods and services based on target consumers’heterogeneous requirements in order to increase omni-channel efficiency.
文摘The development of ethnic minority tourism is currently a hot topic in domestic tourism development.As an important component of Chinese civilization,the Manchu people have created brilliant culture in the long river of historical development.As the hometown of the Manchu people,Fushun has unique folk cultural tourism resources and a strong ethnic flavor.Nowadays,under the promotion of the rural revitalization strategy,the construction of new rural areas is constantly developing,and rural tourism is gradually becoming a new industry.Therefore,in the context of the increasingly prosperous rural tourism industry,it has become increasingly important to combine the ethnic customs of Manchu culture with rural tourism.Taking the ethnic customs and integrated development of rural tourism in Xinbin Manchu Autonomous County of Fushun City,Liaoning Province as the research object,this paper mainly sorts out the current situation and characteristics of rural tourism development in the region,systematically explores the problems in development and how to further optimize development,and proposes new models suitable for the development of folk tourism in Xinbin of Fushun,in order to achieve maximum economic and social benefits and provide a reference for promoting the development of tourism in the region.
文摘End-user computing empowers non-developers to manage data and applications, enhancing collaboration and efficiency. Spreadsheets, a prime example of end-user programming environments widely used in business for data analysis. However, Excel functionalities have limits compared to dedicated programming languages. This paper addresses this gap by proposing a prototype for integrating Python’s capabilities into Excel through on-premises desktop to build custom spreadsheet functions with Python. This approach overcomes potential latency issues associated with cloud-based solutions. This prototype utilizes Excel-DNA and IronPython. Excel-DNA allows creating custom Python functions that seamlessly integrate with Excel’s calculation engine. IronPython enables the execution of these Python (CSFs) directly within Excel. C# and VSTO add-ins form the core components, facilitating communication between Python and Excel. This approach empowers users with a potentially open-ended set of Python (CSFs) for tasks like mathematical calculations, statistical analysis, and even predictive modeling, all within the familiar Excel interface. This prototype demonstrates smooth integration, allowing users to call Python (CSFs) just like standard Excel functions. This research contributes to enhancing spreadsheet capabilities for end-user programmers by leveraging Python’s power within Excel. Future research could explore expanding data analysis capabilities by expanding the (CSFs) functions for complex calculations, statistical analysis, data manipulation, and even external library integration. The possibility of integrating machine learning models through the (CSFs) functions within the familiar Excel environment.
文摘To effectively evaluate the fuzziness of the market environment in product planning,a customer requirements analysis method based on multiple preference information is proposed.Firstly,decision-makers use a preferred information form to evaluate the importance of each customer requirement.Secondly,a transfer function is employed to unify various forms of preference information into a fuzzy complementary judgment matrix.The ranking vector is then calculated using row and normalization methods,and the initial importance of customer requirements is obtained by aggregating the weights of decision members.Finally,the correction coefficients of initial importance and each demand are synthesized,and the importance of customer requirements is determined through normalization.The development example of the PE jaw crusher demonstrates the effectiveness and feasibility of the proposed method.
文摘Customer churns remains a key focus in this research, using artificial intelligence-based technique of machine learning. Research is based on the feature-based analysis four main features were used that are selected on the basis of our customer churn to deduct the meaning full analysis of the data set. Data-set is taken from the Kaggle that is about the fine food review having more than half a million records in it. This research remains on feature based analysis that is further concluded using confusion matrix. In this research we are using confusion matrix to conclude the customer churn results. Such specific analysis helps e-commerce business for real time growth in their specific products focusing more sales and to analyze which product is getting outage. Moreover, after applying the techniques, Support Vector Machine and K-Nearest Neighbour perform better than the random forest in this particular scenario. Using confusion matrix for obtaining the results three things are obtained that are precision, recall and accuracy. The result explains feature-based analysis on fine food reviews, Amazon at customer churn Support Vector Machine performed better as in overall comparison.
文摘Blockchain technology is a shared database of logs of all consumer transactions which are registered on all machines on a network.Both transactions in the system are carried out by consensus processes and to preserve confidentiality all thefiles contained cannot be changed.Blockchain technology is the fundamental software behind digital currencies like Bitcoin,which is common in the marketplace.Cloud computing is a method of using a network of external machines to store,monitor,and process information,rather than using the local computer or a local personal computer.The software is currently facing multiple problems including lack of data protection,data instability,and reliability.This paper aims to give the highest security for multiple user environments in cloud for storing and accessing the data in blocks.The users who are legitimate are only allowed for storing and accessing the data as like a secured block chain approach.As like the Blockchain which does not require a centralized system for transactions,the proposed system is also independent on centralized network interface.The decentralized system is developed in such a way to avoid counterfeiting.The system enables the fabricator to spend less or null resources to perform the validations for its direct operated stores.This ensures the product fabricator to avoid the circulation of its duplicate products.The customer as an end-user is also ensured to have only the genuine products from the fabricator.The Fabricator(F),Merchant(M)and consumer(C)forms an interconnected triangular structure without allowing any counterfeiting agents in their secured cloud chain.The pro-posed approach provides the stability in the security system of the cloud using the chaining mechanism within different blocks at each node.It takes roughly 4.7,6.2,and 7.5 ms,respectively,to register each node in the proposed system for 5,10,and 15 nodes.The overall registration time for each scenario is 11.9,26.2,and 53.1 ms,despite the fact that each node’s registration time was greatest for 10 nodes.By looking at the data,it’s clear that the number of nodes is a func-tion of time.
文摘This paper presents a Model-Based Design(MBD)approach for the design and control of a customized manipulator intended for drilling and position-ing of dental implants accurately with minimal human intervention.While performing an intra-oral surgery for a prolonged duration within a limited oral cavity,the tremor of dentist's hand is inevitable.As a result,wielding the drilling tool and inserting the dental implants safely in accurate position and orientation is highly challenging even for experienced dentists.Therefore,we introduce a customized manipulator that is designed ergonomically by taking in to account the dental chair specifications and anthropomorphic data such that it can be readily mounted onto the existing dental chair.The manipulator can be used to drill holes for dental inserts and position them with improved accuracy and safety.Further-more,a thorough multi-body motion analysis of the manipulator was carried out by creating a virtual prototype of the manipulator and simulating its controlled movements in various scenarios.The overall design was prepared and validated in simulation using Solid works,MATLAB and Simulink through Model Based Design(MBD)approach.The motion simulation results indicate that the manipulator could be built as a prototype readily.
文摘By providing real-time updates of essential information, airports not only display and disseminate information but also help control the flow of traffic. In order to maximize available space, particularly in high traffic areas, Airport Display Information Systems should be integrated into the overall design of the airport and their positioning should be carefully planned to deliver optimal results. Airport Display Information Systems can help airports maximize space, increase customer satisfaction, and generate new revenue opportunities. The technology is designed not only to comply with environmental regulations, but also to help airports keep budgets in check. This paper discusses airport display systems, their connections and interoperability with other systems and who the key airport users of these airport display systems are.
文摘The purpose of this paper is to provide empirical evidence for the validity of the relationship between service-oriented manufacturing information system (SMIS) customization and performance from three aspects: data flexibility, process flexibility and system flexibility. We select some questionnaires from the third round of High-performance manufacturing (HPM) data to construct the construct, verify the reliability and validity of the construct, extract principal components, and analyze the mediating effect by using multiple chain linear regression and structural equation model. The results show that SMIS customization has a significant impact on its performance, and this effect works through its flexibility. More specifically, it is the multiple chain mediation effect composed of data flexibility, process flexibility and system flexibility. The importance of SMIS customization and flexibility to the organization is made clear, which helps practitioners understand the internal mechanism that affects SMIS performance, so as to use limited resources to improve system performance.
文摘The following paper is a brief theoretical approach to the state of the art in relation to the new demands of society in the area of climate and weather-related services for health. Apart from the study of the impacts of climate change on health which requires a longer consideration, a special emphasis is given to the area of weather-related services based on biometeorological forecasting. A new way of understanding the interaction between atmospheric factors and living organisms is presented and some biometeorological indexes already developed are shown. Customized biometeorological services must be constructed in the field of human health based on the ICTs development and the amount of climatic data available but new approaches and scientific methods are required to success in achieving this enterprise.
文摘Customer churn may be a critical issue for banks. The extant literature on statistical and machine learning for customer churn focuses on the problem of correctly predicting that a customer is about to switch bank, while very rarely consid-ers the problem of generating personalized actions to improve the customer retention rate. However, these decisions are at least as critical as the correct identification of customers at risk. The decision of what actions to deliver to what customers is normally left to managers who can only rely upon their knowledge. By looking at the scientific literature on CRM and personalization, this research proposes a number of models which can be used to generate marketing ac-tions, and shows how to integrate them into a model embracing both the analytical prediction of customer churn and the generation of retention actions. The benefits and risks associated with each approach are discussed. The paper also describes a case of application of a predictive model of customer churn in a retail bank where the analysts have also generated a set of personalized actions to retain customers by using one of the approaches presented in the paper, namely by adapting a recommender system approach to the retention problem.
文摘With a view to accelerating the construction and development of the free trade zones and the foreign trade business of enterprises within the said zones, and making entering or leaving the zones convenient for those enterprises; the Customs shall in accordance with the newly promulgated regulations as stipulated in Supervising Measures of the Customs in Free Trade Zones require that consigness, consignors or their agents register for the record their car.
文摘The profitability of the system product is decided on the sales of the product. Furthermore, a customer satisfaction for products quality and a price have a big influence on the sales of the product. It spends limited financial resources effectively to raise the profitability of the system product, and it is necessary to realize the high quality product correspond to the customer needs as much as possible. There may be close relationship between cost of a product and an expense to implement the individual inherent attribute of system product. For the purpose of improvement of the customer satisfaction for quality of system product, the method of quantitative quality requirement and evaluation based on the ISO/IEC9126 quality model that includes six quality characteristics is widely recognized. However, independency among each quality characteristic has not been sure and the suitability of method for quality requirement of system product by using these six quality characteristics could not certified statistically. In the precedent study, introduced the requirements definition method for the quality of system product based on the system quality model defined in ISO/IEC9126 and proposed the effectiveness of it statistically. This study have measured the customer satisfaction for the system quality from the viewpoint of six quality characteristics quantitatively and confirmed the effectiveness of the technique to evaluate. In this study, we have confirmed the relationship between inherent attributes of the product and quantitative result of a measured value of total customer satisfaction from the view point of six quality characteristics statistically. This study performed the trial to clarify the relations with the inherent attributes that quantitative result of a measurement of the customer satisfaction based on six quality characteristics by the quality model of ISO/IEC9126. In addition, this study performed the development of the prediction model to estimate the total customer satisfaction for the system product from the view point of inherent attribute of the product. In this paper, we propose the effectiveness of application of the estimated prediction model and possibility of improvement of the total customer satisfaction of a system product.
基金funded by The National Natural Science Foundation of China(81872199)Key Program of National Natural Science Foundation of China(82030085)+4 种基金The National Key Research and Development Program of China(2017YFC0908500)The National Natural Science Foundation of China(82002853)China Postdoctoral Science Foundation(2019M661565)Innovative Research Team of High-level Local Universities in Shanghai(SHSMU-ZLCX20212300,SSMU-ZLCX20180500)funded by“Shuguang Program”supported by Shanghai Education Development Foundation and Shanghai Municipal Education Commission(19SG13)。
文摘Cancer cell membrane(CCM)derived nanotechnology functionalizes nanoparticles(NPs)to recognize homologous cells,exhibiting translational potential in accurate tumor therapy.However,these nanoplatforms are majorly generated from fixed cell lines and are typically evaluated in cell line-derived subcutaneous-xenografts(CDX),ignoring the tumor heterogeneity and differentiation from inter-and intra-individuals and microenvironments between heterotopic-and orthotopic-tumors,limiting the therapeutic efficiency of such nanoplatforms.Herein,various biomimetic nanoplatforms(CCM-modified gold@Carbon,i.e.,Au@C-CCM)were fabricated by coating CCMs of head and neck squamous cell carcinoma(HNSCC)cell lines and patient-derived cells on the surface of Au@C NP.The generated Au@C-CCMs were evaluated on corresponding CDX,tongue orthotopic xenograft(TOX),immunecompetent primary and distant tumor models,and patient-derived xenograft(PDX)models.The Au@C-CCM generates a photothermal conversion efficiency up to 44.2% for primary HNSCC therapy and induced immunotherapy to inhibit metastasis via photothermal therapy-induced immunogenic cell death.The homologous CCM endowed the nanoplatforms with optimal targeting properties for the highest therapeutic efficiency,far above those with mismatched CCMs,resulting in distinct tumor ablation and tumor growth inhibition in all four models.This work reinforces the feasibility of biomimetic NPs combining modular designed CMs and functional cores for customized treatment of HNSCC,can be further extended to other malignant tumors therapy.
基金This work is supported by the National Natural Science Foundation of China(Nos.72071150,71871174).
文摘As the banking industry gradually steps into the digital era of Bank 4.0,business competition is becoming increasingly fierce,and banks are also facing the problem of massive customer churn.To better maintain their customer resources,it is crucial for banks to accurately predict customers with a tendency to churn.Aiming at the typical binary classification problem like customer churn,this paper establishes an early-warning model for credit card customer churn.That is a dual search algorithm named GSAIBAS by incorporating Golden Sine Algorithm(GSA)and an Improved Beetle Antennae Search(IBAS)is proposed to optimize the parameters of the CatBoost algorithm,which forms the GSAIBAS-CatBoost model.Especially,considering that the BAS algorithm has simple parameters and is easy to fall into local optimum,the Sigmoid nonlinear convergence factor and the lane flight equation are introduced to adjust the fixed step size of beetle.Then this improved BAS algorithm with variable step size is fused with the GSA to form a GSAIBAS algorithm which can achieve dual optimization.Moreover,an empirical analysis is made according to the data set of credit card customers from Analyttica official platform.The empirical results show that the values of Area Under Curve(AUC)and recall of the proposedmodel in this paper reach 96.15%and 95.56%,respectively,which are significantly better than the other 9 common machine learning models.Compared with several existing optimization algorithms,GSAIBAS algorithm has higher precision in the parameter optimization for CatBoost.Combined with two other customer churn data sets on Kaggle data platform,it is further verified that the model proposed in this paper is also valid and feasible.