Although it is known that in most angiosperms mitosis in early endosperm development is syncytial and synchronized, it is unclear how the synchronization is regulated. We showed previously that APC11, also named ZYGI,...Although it is known that in most angiosperms mitosis in early endosperm development is syncytial and synchronized, it is unclear how the synchronization is regulated. We showed previously that APC11, also named ZYGI, in Arabidopsis activates zygote division by interaction and degradation of cyclin B1. Here, we report that the mutation in APC11/ZYG1 led to unsynchronized mitosis and over-accumulation of cyclin B1-GUS in the endosperm. Mutations in two other APC subunits showed similar defects. Transgenic expression of stable cyclin B1 in the endosperm also caused unsynchronized mitosis. Further, downregulation of APC11 generated multi-nucleate somatic cells with unsynchronized mitotic division. Together, our results suggest that APC/C-mediated cyclin B1 degradation is critical for cell cycle synchronization.展开更多
In this article, we propose a novel, multilevel, dynamic factor model, to determine endogenously clustered regions for the investigation of regional clustering and synchronization of provincial business fluctuations i...In this article, we propose a novel, multilevel, dynamic factor model, to determine endogenously clustered regions for the investigation of regional clustering and synchronization of provincial business fluctuations in China. The parameter identification and model estimation was conducted using the Markov Chain Monte Carlo method. We then conducted an empirical study of the provincial business fluctuations in China(31 Chinese provinces are considered except Hong Kong, Macao, and Taiwan due to the data unavailability), which were sampled from January 2000 to December 2015. Our results indicated that these provinces could be clustered into four regions: leading, coincident, lagging, and overshooting. In comparison with traditional geographical divisions, this novel clustering into four regions enabled the regional business cycle synchronization to be more accurately captured. Within the four regional clusters it was possible to identify substantial heterogeneities among regional business cycle fluctuations, especially during the periods of the 2008 financial crisis and the ‘four-trillion economic stimulus plan'.展开更多
Several global conclusions about an Ebenman's model of a population with competing juveniles and adults are derived in this paper. The problems about the number of non-trivial fixed points, the number of synchrono...Several global conclusions about an Ebenman's model of a population with competing juveniles and adults are derived in this paper. The problems about the number of non-trivial fixed points, the number of synchronous 2-cycles, and the number of attracting synchronous cycles are resolved. In a special case, the twice iteration of the 2-dimensional map can be reduced to a 1-dimensional map, and the existence of one or more continua of non-synchronous 2-cycles is pointed out. Numerical calculations are used to draw orbit diagrams which show complicated dynamics of this non-invertible 2-dimensional map. Experimental and field observational evidence is also discussed.展开更多
基金supported by“Mechanistic dissection of plant embryo and seed development“project(2014CB943401)from The National Basic Research Program,the Ministry of Science and Technology of China
文摘Although it is known that in most angiosperms mitosis in early endosperm development is syncytial and synchronized, it is unclear how the synchronization is regulated. We showed previously that APC11, also named ZYGI, in Arabidopsis activates zygote division by interaction and degradation of cyclin B1. Here, we report that the mutation in APC11/ZYG1 led to unsynchronized mitosis and over-accumulation of cyclin B1-GUS in the endosperm. Mutations in two other APC subunits showed similar defects. Transgenic expression of stable cyclin B1 in the endosperm also caused unsynchronized mitosis. Further, downregulation of APC11 generated multi-nucleate somatic cells with unsynchronized mitotic division. Together, our results suggest that APC/C-mediated cyclin B1 degradation is critical for cell cycle synchronization.
基金Under the auspices of the National Natural Science Foundation of China(No.71371160)the Program for Changjiang Youth Scholars(No.Q2016131)the Program for New Century Excellent Talents in University(No.NCET-13-0509)
文摘In this article, we propose a novel, multilevel, dynamic factor model, to determine endogenously clustered regions for the investigation of regional clustering and synchronization of provincial business fluctuations in China. The parameter identification and model estimation was conducted using the Markov Chain Monte Carlo method. We then conducted an empirical study of the provincial business fluctuations in China(31 Chinese provinces are considered except Hong Kong, Macao, and Taiwan due to the data unavailability), which were sampled from January 2000 to December 2015. Our results indicated that these provinces could be clustered into four regions: leading, coincident, lagging, and overshooting. In comparison with traditional geographical divisions, this novel clustering into four regions enabled the regional business cycle synchronization to be more accurately captured. Within the four regional clusters it was possible to identify substantial heterogeneities among regional business cycle fluctuations, especially during the periods of the 2008 financial crisis and the ‘four-trillion economic stimulus plan'.
文摘Several global conclusions about an Ebenman's model of a population with competing juveniles and adults are derived in this paper. The problems about the number of non-trivial fixed points, the number of synchronous 2-cycles, and the number of attracting synchronous cycles are resolved. In a special case, the twice iteration of the 2-dimensional map can be reduced to a 1-dimensional map, and the existence of one or more continua of non-synchronous 2-cycles is pointed out. Numerical calculations are used to draw orbit diagrams which show complicated dynamics of this non-invertible 2-dimensional map. Experimental and field observational evidence is also discussed.
