A new cerebroside,1-O-(β-D-glucopyranosyloxy)-(2S,3R,4E,8Z)-2-[(2′R)-2’-hydroxylignoceranoylamino]-4,8-tetradecene-3- diol was isolated from the 60%EtOH extract of traditional Chinese medical plant Cyperus rotundus...A new cerebroside,1-O-(β-D-glucopyranosyloxy)-(2S,3R,4E,8Z)-2-[(2′R)-2’-hydroxylignoceranoylamino]-4,8-tetradecene-3- diol was isolated from the 60%EtOH extract of traditional Chinese medical plant Cyperus rotundus L.Its structure was determined on the basis of spectroscopic data.This new compound showed anti-proliferation effect on vascular smooth muscle cells(VSMCs).展开更多
Oil spills may considerably damage sensitive coastal wetlands. The phytoremediation potential and restoration of a dominant coastal marsh plant, Cyperus rotundus, for diesel pollutant and its phytoremediation effectiv...Oil spills may considerably damage sensitive coastal wetlands. The phytoremediation potential and restoration of a dominant coastal marsh plant, Cyperus rotundus, for diesel pollutant and its phytoremediation effectiveness were investigated in this open-air pot experiment. Cyperus rotundus was transplanted into soil contaminated with diesel at concentrations of 1 000, 5 000, 10 000, 15 000, 20 000 mg/kg. In order to better elucidate the biochemical and physiological responses to diesel pollutants, activity of the antioxidant enzymes peroxidase （POD）, catalase （CAT） and ascorbic acid oxidase （AAO） were determined in the plant tissue after 50 d treatment at the levels mentioned above. The results showed that CAT and AAO of stem and leaf exhibited peak enzyme activities on 15 000 mg/kg soil and 10 000 mg/kg soil respectively, and declined at higher concentrations. Additionally, the increment of biomass and the content of soluble protein, as well as chlorophyll content were affected by diesel. The highest restoration effectiveness appeared at the level of 5 000 mg/kg. Collectively, Cyperus rotundus is a potential plant which can be used for restoring the diesel-contaminated soil.展开更多
Cyperus rotundus(Cyperaceae)is used as an analgesic and sedative in oriental medicine,and has been reported to exhibit anti-nociceptive and anti-inflammatory effects.On the other hand,transient receptor potential vani...Cyperus rotundus(Cyperaceae)is used as an analgesic and sedative in oriental medicine,and has been reported to exhibit anti-nociceptive and anti-inflammatory effects.On the other hand,transient receptor potential vanilloid channel 1(TRPV1),the so-called capsaicin receptor,is a nonselective cation channel that senses various noxious chemical and thermal stimuli.However,it has recently展开更多
Objective: To explore the potential of essential oil, as therapeutic molecule source, from olibanum of Boswellia papyrifera(Burseraceae), leafy stems of Cymbopogon schoenanthus(Poaceae) and Croton zambesicus(Euphorbia...Objective: To explore the potential of essential oil, as therapeutic molecule source, from olibanum of Boswellia papyrifera(Burseraceae), leafy stems of Cymbopogon schoenanthus(Poaceae) and Croton zambesicus(Euphorbiaceae) and rhizome of Cyperus rotundus(Cyperaceae) found in Sudan. Respective essential oil was evaluated for antiproliferative, antibacterial and antioxidant activity. Methods: Essential oils were extracted by hydrodistillation and then analysed by gas chromatography coupled to mass spectrometry(GCMS). Anti-proliferative activity was determined against human cell lines(MCF7 and MDAMB231, HT29 and HCT116) by the thiazolyl blue tetrazolium bromide(MTT) procedure. Antioxidant activity was evaluated by diphenyl 2 pycril hydrazil(DPPH) assay. Antibacterial activity was determined against two Gram-positive and two Gram-negative bacteria by microdilution method. Results: The essential oil from olibanum of Boswellia papyriferacontained mainly alcohol and ester derivatives(46.82%) while monoterpenes(69.84%) dominated in Corton zambesicus oil. Sesquiterpenes were the most highly represented classes of terpene derivatives in Cyperus schoenanthus(71.59%) and Cyperus rotundus(44.26%). Oil of Cymbopogon schoenanthus revealed the best anti-proliferative activity against HCT116 cell line with IC50 value at(19.1 ± 2.0) μg/m L. Oil of Croton zambesicus showed the best antioxidant activity [EC50(4.20 ± 0.19) mg/m L]. All oils showed good antibacterial activity against Escherichia coli, Bacillus subtilis and Staphylococcus aureus with minimum inhibitory concentration(MIC) value ranged from 16 to 250 μg/m L. Conclusions: The results suggest that the essential oils of these plants could be used as a source of natural anti-proliferative, antioxidant and antibacterial agents.展开更多
基金supported by 2006 Great Basic Science Research Project of Jiangsu College and University(No. 06KJA36022)
文摘A new cerebroside,1-O-(β-D-glucopyranosyloxy)-(2S,3R,4E,8Z)-2-[(2′R)-2’-hydroxylignoceranoylamino]-4,8-tetradecene-3- diol was isolated from the 60%EtOH extract of traditional Chinese medical plant Cyperus rotundus L.Its structure was determined on the basis of spectroscopic data.This new compound showed anti-proliferation effect on vascular smooth muscle cells(VSMCs).
基金Project supported by the National Natural Science Foundation of China (Grant Nos.40973073, 41073072)the Shanghai Leading Academic Discipline Project (Grant No.S30109),and the Technology Foundation of Shanghai University
文摘Oil spills may considerably damage sensitive coastal wetlands. The phytoremediation potential and restoration of a dominant coastal marsh plant, Cyperus rotundus, for diesel pollutant and its phytoremediation effectiveness were investigated in this open-air pot experiment. Cyperus rotundus was transplanted into soil contaminated with diesel at concentrations of 1 000, 5 000, 10 000, 15 000, 20 000 mg/kg. In order to better elucidate the biochemical and physiological responses to diesel pollutants, activity of the antioxidant enzymes peroxidase （POD）, catalase （CAT） and ascorbic acid oxidase （AAO） were determined in the plant tissue after 50 d treatment at the levels mentioned above. The results showed that CAT and AAO of stem and leaf exhibited peak enzyme activities on 15 000 mg/kg soil and 10 000 mg/kg soil respectively, and declined at higher concentrations. Additionally, the increment of biomass and the content of soluble protein, as well as chlorophyll content were affected by diesel. The highest restoration effectiveness appeared at the level of 5 000 mg/kg. Collectively, Cyperus rotundus is a potential plant which can be used for restoring the diesel-contaminated soil.
基金supported by a grant of the Korean Health Technology R&D Project,Ministry of Health&Welfare,Republic of Korea(Grant No.:HN12C0057)
文摘Cyperus rotundus(Cyperaceae)is used as an analgesic and sedative in oriental medicine,and has been reported to exhibit anti-nociceptive and anti-inflammatory effects.On the other hand,transient receptor potential vanilloid channel 1(TRPV1),the so-called capsaicin receptor,is a nonselective cation channel that senses various noxious chemical and thermal stimuli.However,it has recently
文摘Objective: To explore the potential of essential oil, as therapeutic molecule source, from olibanum of Boswellia papyrifera(Burseraceae), leafy stems of Cymbopogon schoenanthus(Poaceae) and Croton zambesicus(Euphorbiaceae) and rhizome of Cyperus rotundus(Cyperaceae) found in Sudan. Respective essential oil was evaluated for antiproliferative, antibacterial and antioxidant activity. Methods: Essential oils were extracted by hydrodistillation and then analysed by gas chromatography coupled to mass spectrometry(GCMS). Anti-proliferative activity was determined against human cell lines(MCF7 and MDAMB231, HT29 and HCT116) by the thiazolyl blue tetrazolium bromide(MTT) procedure. Antioxidant activity was evaluated by diphenyl 2 pycril hydrazil(DPPH) assay. Antibacterial activity was determined against two Gram-positive and two Gram-negative bacteria by microdilution method. Results: The essential oil from olibanum of Boswellia papyriferacontained mainly alcohol and ester derivatives(46.82%) while monoterpenes(69.84%) dominated in Corton zambesicus oil. Sesquiterpenes were the most highly represented classes of terpene derivatives in Cyperus schoenanthus(71.59%) and Cyperus rotundus(44.26%). Oil of Cymbopogon schoenanthus revealed the best anti-proliferative activity against HCT116 cell line with IC50 value at(19.1 ± 2.0) μg/m L. Oil of Croton zambesicus showed the best antioxidant activity [EC50(4.20 ± 0.19) mg/m L]. All oils showed good antibacterial activity against Escherichia coli, Bacillus subtilis and Staphylococcus aureus with minimum inhibitory concentration(MIC) value ranged from 16 to 250 μg/m L. Conclusions: The results suggest that the essential oils of these plants could be used as a source of natural anti-proliferative, antioxidant and antibacterial agents.
