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《中华人民共和国药典》药用辅料相关标准中元素杂质与ICH Q3D协调策略分析
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作者 蔡立荣 陈蕾 +2 位作者 李昌亮 郑金凤 刘雁鸣 《医药导报》 北大核心 2025年第2期223-227,共5页
目的通过对《中华人民共和国药典》(简称《中国药典》)目前收载的药用辅料元素杂质与ICH Q3D的差异进行分析和评估,探讨两者之间的协调策略。方法总结并梳理《中国药典》2020年版及其第一增补本中通则及药用辅料品种正文与ICHQ3D的主要... 目的通过对《中华人民共和国药典》(简称《中国药典》)目前收载的药用辅料元素杂质与ICH Q3D的差异进行分析和评估,探讨两者之间的协调策略。方法总结并梳理《中国药典》2020年版及其第一增补本中通则及药用辅料品种正文与ICHQ3D的主要差异。结果结合国外药典元素杂质的协调策略以及药用辅料品种风险评估结果,提出《中国药典》药用辅料标准的协调策略和路径。结论应结合药用辅料品种的风险等级,对《中国药典》药用辅料品种进行系统的元素杂质风险评估,并根据评估结果,确定修订方式并持续更新。 展开更多
关键词 中华人民共和国药典 药用辅料 ICH q3d 元素杂质
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3D Printing of Tough Hydrogel Scaffolds with Functional Surface Structures for Tissue Regeneration
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作者 Ke Yao Gaoying Hong +11 位作者 Ximin Yuan Weicheng Kong Pengcheng Xia Yuanrong Li Yuewei Chen Nian Liu Jing He Jue Shi Zihe Hu Yanyan Zhou Zhijian Xie Yong He 《Nano-Micro Letters》 SCIE EI CAS 2025年第2期18-45,共28页
Hydrogel scaffolds have numerous potential applications in the tissue engineering field.However,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and hi... Hydrogel scaffolds have numerous potential applications in the tissue engineering field.However,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and high mechanical properties.Inspired by Chinese ramen,we propose a universal fabricating method(printing-P,training-T,cross-linking-C,PTC&PCT)for tough hydrogel scaffolds to fill this gap.First,3D printing fabricates a hydrogel scaffold with desired structures(P).Then,the scaffold could have extraordinarily high mechanical properties and functional surface structure by cycle mechanical training with salting-out assistance(T).Finally,the training results are fixed by photo-cross-linking processing(C).The tough gelatin hydrogel scaffolds exhibit excellent tensile strength of 6.66 MPa(622-fold untreated)and have excellent biocompatibility.Furthermore,this scaffold possesses functional surface structures from nanometer to micron to millimeter,which can efficiently induce directional cell growth.Interestingly,this strategy can produce bionic human tissue with mechanical properties of 10 kPa-10 MPa by changing the type of salt,and many hydrogels,such as gelatin and silk,could be improved with PTC or PCT strategies.Animal experiments show that this scaffold can effectively promote the new generation of muscle fibers,blood vessels,and nerves within 4 weeks,prompting the rapid regeneration of large-volume muscle loss injuries. 展开更多
关键词 3d printing Tough hydrogel scaffold functional surface structure Tissue regeneration BIOMATERIALS
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基于DQN-CE算法的电-热综合能源系统能量管理策略
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作者 朱杰杰 皮志勇 +1 位作者 陈代才 谭洪 《浙江电力》 2025年第1期44-53,共10页
针对电-热综合能源系统中可再生能源输出的不确定性和间歇性问题,提出一种电-热综合能源系统能量管理的强化学习方法,以电-热综合能源系统运行成本最低为目标,实现综合能源系统的能量管理。首先,建立电-热综合能源系统能量管理模型;然后... 针对电-热综合能源系统中可再生能源输出的不确定性和间歇性问题,提出一种电-热综合能源系统能量管理的强化学习方法,以电-热综合能源系统运行成本最低为目标,实现综合能源系统的能量管理。首先,建立电-热综合能源系统能量管理模型;然后,将含可再生能源的电-热综合能源系统能量管理过程转化为马尔可夫决策过程,并采用融合NoisyNet(噪声网络)和自注意力机制的DQN-CE(深度Q网络-交叉熵)算法对智能体进行交互学习训练。最后,通过算例分析表明,所提方法训练的智能体能够实时响应可再生能源的不确定性,并能在线管理包含可再生能源在内的电-热综合能源系统的能量。 展开更多
关键词 噪声网络 深度q网络 自注意力机制 交叉熵损失函数
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THE(p,q)-ANALOG OF MULTIVALENT BAZILEVIC FUNCTIONS ASSOCIATED WITH A LIMACON
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作者 HUANG An LONG Pin-hong +1 位作者 LIU Jin-lin Gangadharan Murugusundaramoorthy 《数学杂志》 2024年第6期471-484,共14页
This paper studies the problem of functional inequalities for analytic functions in classical geometric function theory.Using the di erential subordination principle and(p,q)-derivative operator,it introduces(p,q)-ana... This paper studies the problem of functional inequalities for analytic functions in classical geometric function theory.Using the di erential subordination principle and(p,q)-derivative operator,it introduces(p,q)-analog of a class of multivalently Bazilevic functions as-sociated with a limacon function,and obtains the corresponding coefficient estimates and the Fekete-Szego inequality,which extend and improve the related results for starlike functions,even q-starlike functions. 展开更多
关键词 Fekete-Szego inequality symmetric Toeplitz determinant multivalent function Bazilevic function (p q)-derivative operator
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La-Ce稀土对Q345D钢夹杂物和冲击性能的影响 被引量:2
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作者 罗钢 隋亚飞 +2 位作者 刘彭 梁亮 徐李军 《特殊钢》 2024年第3期33-39,共7页
通过现场试验,分析了La-Ce稀土处理对Q345D结构钢夹杂物、连铸可浇性和钢种性能的影响。结果表明,RE在Q345D结构钢中的合金收得率为21.5%;与未添加RE的炉次相比,脱硫率提高了37.5%,单位夹杂物密度从80.16个/mm^(2),降低至60.78个/mm^(2)... 通过现场试验,分析了La-Ce稀土处理对Q345D结构钢夹杂物、连铸可浇性和钢种性能的影响。结果表明,RE在Q345D结构钢中的合金收得率为21.5%;与未添加RE的炉次相比,脱硫率提高了37.5%,单位夹杂物密度从80.16个/mm^(2),降低至60.78个/mm^(2);La-Ce稀土处理前钢液中夹杂物主要是MgO-Al_(2)O_(3)-CaO复合夹杂,La-Ce稀土处理对小尺寸(D≤5μm)夹杂物的改性作用较为明显,小尺寸夹杂物改性为(La-Ce-S)和(La-Ce-Al-S-O)稀土类夹杂物;La-Ce稀土处理可以明显降低钢中MnS类夹杂物的纵横比,使MnS类夹杂物在轧制后的形貌更接近椭圆形,而没有长线形,这是Q345D结构钢横向冲击功提高20%的主要原因。 展开更多
关键词 La-Ce稀土处理 q345d结构钢 横向冲击功 夹杂物改性 精炼 洁净度
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基于D3QN的火力方案优选方法
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作者 佘维 岳瀚 +1 位作者 田钊 孔德锋 《火力与指挥控制》 CSCD 北大核心 2024年第8期166-174,共9页
针对在多类弹药协同攻击地面工事类目标任务中火力方案优选效率低的问题,提出一种基于双层决斗DQN(dueling double deep Q network,D3QN)的火力方案优选方法。该方法将打击过程建模为马尔科夫决策过程(Markov decision processes,MDP),... 针对在多类弹药协同攻击地面工事类目标任务中火力方案优选效率低的问题,提出一种基于双层决斗DQN(dueling double deep Q network,D3QN)的火力方案优选方法。该方法将打击过程建模为马尔科夫决策过程(Markov decision processes,MDP),设计其状态空间和动作空间,设计综合奖励函数激励火力方案生成策略优化,使智能体通过强化学习框架对策略进行自主训练。仿真实验结果表明,该方法对地面工事类目标的火力方案进行决策,相较于传统启发式智能算法能够获得较优的火力方案,其计算效率和结果的稳定性相较于传统深度强化学习算法具有更明显的优势。 展开更多
关键词 深度强化学习 深度q网络 d3qN 组合优化 火力方案优选
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基于d-q变换及WOA-LSTM的异步电机定子匝间短路故障诊断方法
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作者 王喜莲 秦嘉翼 耿民 《电机与控制学报》 EI CSCD 北大核心 2024年第6期56-65,共10页
为了实现对异步电机定子绕组匝间短路故障的可靠在线诊断,提出一种基于d-q变换及鲸鱼优化算法(WOA)优化的长短期记忆网络(LSTM)的故障诊断方法。通过理论推导可知,d-q变换可有效提取定子电流中的特征频谱数据。采用鲸鱼优化算法对长短... 为了实现对异步电机定子绕组匝间短路故障的可靠在线诊断,提出一种基于d-q变换及鲸鱼优化算法(WOA)优化的长短期记忆网络(LSTM)的故障诊断方法。通过理论推导可知,d-q变换可有效提取定子电流中的特征频谱数据。采用鲸鱼优化算法对长短期记忆网络中的3个关键参数进行优化,建立WOA-LSTM故障分类模型。为了验证基于d-q变换和WOA-LSTM故障诊断方法的有效性,分别以小波变换、快速傅里叶变换及d-q变换提取电流频谱数据作为输入数据集,以一台YE2-100L1-4型异步电机为实验对象进行实验验证。研究结果表明:相比于小波变换及快速傅里叶变换,采用d-q变换能更准确的提取出定子电流中的故障特征,更精确地反映电机故障状态,有助于提高故障分类准确率;相比于传统的LSTM算法,经WOA优化后的LSTM算法分类准确率可达98.3%,能可靠地实现不同程度匝间短路故障的诊断。 展开更多
关键词 异步电机 故障诊断 定子绕组匝间短路 d-q变换理论 鲸鱼优化算法 长短期记忆神经网络
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The quantified analysis of China's GM cotton yield capacity by C-D function and stochastic frontier model
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作者 张涛 薛宝娣 《Hunan Agricultural Science & Technology Newsletter》 2004年第1期11-13,共3页
Using a modified C D function and stochastic frontier model, the paper analyzed China's cotton yield capacity and found that the yield and technical efficiency of China's cotton planting system can be increas... Using a modified C D function and stochastic frontier model, the paper analyzed China's cotton yield capacity and found that the yield and technical efficiency of China's cotton planting system can be increased by the use of genetically modified (GM) varieties. 展开更多
关键词 GM cotton yield capacity C d function stochastic frontier model
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Q690D多道次GMAW接头的组织和力学性能 被引量:1
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作者 刘五兵 王世清 李方坡 《热加工工艺》 北大核心 2024年第3期53-56,61,共5页
在无预热和焊后热处理的条件下,采用熔化极气体保护焊(GMAW)和CHW-80C1实芯焊丝对20 mm厚Q690D热机械轧制钢板进行多道次焊接试验,分析该钢焊接接头的组织转变特征和冲击性能。结果表明,采用CHW-80C1焊丝可获得成型优良的焊接接头;Q690... 在无预热和焊后热处理的条件下,采用熔化极气体保护焊(GMAW)和CHW-80C1实芯焊丝对20 mm厚Q690D热机械轧制钢板进行多道次焊接试验,分析该钢焊接接头的组织转变特征和冲击性能。结果表明,采用CHW-80C1焊丝可获得成型优良的焊接接头;Q690D各道次的焊缝组织相似,均由粒状贝氏体和少量的针状铁素体、先共析铁素体组成;热影响区由粒状贝氏体、针状铁素体、先共析铁素体及M-A组元组成。焊缝与细晶热影响区的冲击吸收功相对于母材的有一定幅度的下降,焊缝与细晶热影响区的断裂类型均为韧性断裂。 展开更多
关键词 q690d 熔化极气体保护焊(GMAW) 显微组织 冲击韧性 断口
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无人驾驶中运用DQN进行障碍物分类的避障方法
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作者 刘航博 马礼 +2 位作者 李阳 马东超 傅颖勋 《计算机工程》 CAS CSCD 北大核心 2024年第11期380-389,共10页
安全是无人驾驶汽车需要考虑的首要因素,而避障问题是解决驾驶安全最有效的手段。基于学习的避障方法因其能够从环境中学习并直接从感知中做出决策的能力而受到研究者的关注。深度Q网络(DQN)作为一种流行的强化学习方法,在无人驾驶避障... 安全是无人驾驶汽车需要考虑的首要因素,而避障问题是解决驾驶安全最有效的手段。基于学习的避障方法因其能够从环境中学习并直接从感知中做出决策的能力而受到研究者的关注。深度Q网络(DQN)作为一种流行的强化学习方法,在无人驾驶避障领域取得了很大的进展,但这些方法未考虑障碍物类型对避障策略的影响。基于对障碍物的准确分类提出一种Classification Security DQN(CSDQN)的车辆行驶决策框架。根据障碍物的不同类型以及环境信息给出具有更高安全性的无人驾驶决策,达到提高无人驾驶安全性的目的。首先对检测到的障碍物根据障碍物的安全性等级进行分类,然后根据不同类型障碍物提出安全评估函数,利用位置的不确定性和基于距离的安全度量来评估安全性,接着CSDQN决策框架利用障碍物类型、相对位置信息以及安全评估函数进行不断迭代优化获得最终模型。仿真结果表明,与先进的深度强化学习进行比较,在多种障碍物的情况下,采用CSDQN方法相较于DQN和SDQN方法分别提升了43.9%和4.2%的安全性,以及17.8%和3.7%的稳定性。 展开更多
关键词 无人驾驶 深度q网络 分类避障 评估函数 安全性
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基于d-q理论的双馈异步电机定子匝间短路故障诊断方法
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作者 秦嘉翼 周锦晗 +3 位作者 王喜莲 耿民 李志国 张川宝 《北京交通大学学报》 CAS CSCD 北大核心 2024年第2期185-192,共8页
为实现双馈异步电机定子绕组匝间短路的早期故障诊断,提出一种基于转子电流特征频率分量的故障诊断方法 .首先,通过分析故障后电机的电磁特性,得到故障后转子电流中会产生特征频率分量的结论 .然后,通过对转子单相电流进行特殊的相移构... 为实现双馈异步电机定子绕组匝间短路的早期故障诊断,提出一种基于转子电流特征频率分量的故障诊断方法 .首先,通过分析故障后电机的电磁特性,得到故障后转子电流中会产生特征频率分量的结论 .然后,通过对转子单相电流进行特殊的相移构造出三相电流,并对该组电流进行d-q变换,利用理论推导证明d-q变换后的直流分量幅值能够反映特征谐波的大小,将直流分量作为故障特征量进行双馈异步电机匝间短路故障的诊断.最后,依据有限元法建立故障前后电机的仿真模型,对不同工况下故障特征量的变化进行研究.结果表明:基于d-q理论提取的故障特征量与定子绕组的短路匝数呈正相关,且在转速变化和电压不平衡时也可有效诊断出匝间短路故障;通过设置合理的故障阈值可实现对双馈异步电机定子绕组匝间短路故障的精确辨识.研究结果可以为电机绕组匝间短路故障诊断提供参考. 展开更多
关键词 双馈异步电机 定子绕组匝间短路 故障诊断 d-q变换理论
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Q355D特厚核电模块用同质复合钢板生产技术分析
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作者 周全 魏茹 《冶金与材料》 2024年第11期41-43,共3页
核电领域生产发展期间,对特厚钢板的需求量不断提升,但板材均匀性、探伤检测、Z向性能等方面存在较高的技术生产难度。为促进核电领域稳步发展,文章以Q355D特厚钢板为研究对象,围绕Q355D特厚核电模块用同质复合钢板生产技术展开深入探究... 核电领域生产发展期间,对特厚钢板的需求量不断提升,但板材均匀性、探伤检测、Z向性能等方面存在较高的技术生产难度。为促进核电领域稳步发展,文章以Q355D特厚钢板为研究对象,围绕Q355D特厚核电模块用同质复合钢板生产技术展开深入探究,指出核心生产技术要点。研究结果表明,通过运用连铸坯真空复合轧制生产技术,可得到高品质的Q355D特厚钢板,符合核电模块用钢要求,有助于创造更大的生产效益、核电效益。 展开更多
关键词 q355d钢材 特厚 核电模块 生产技术
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Stability of a Neutral Stochastic Functional Differential Equations 被引量:1
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作者 LI Bi-wen~1,21. Department of Mathematics, Hubei Normal University, Huangshi 435002, Hubei, China 2. Department of Mathematics, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China 《Wuhan University Journal of Natural Sciences》 EI CAS 2005年第6期957-960,共4页
Sufficient condition for stochastic unifrom stability of a neutral stochastic functional differential equation is given, especially, new techniques are developed to cope with the neutral delay case, we obtained the su... Sufficient condition for stochastic unifrom stability of a neutral stochastic functional differential equation is given, especially, new techniques are developed to cope with the neutral delay case, we obtained the sufficient condition for asymptotic stability of neutral stochastic differential delay equations. Due to the new techniques developed in this paper, the results obtained arc very general and useful. The theory developed here gives a unified treatment for various asymptotic estimates e.g. exponential and polynomial bounds. 展开更多
关键词 Lyapunov function d operator It's formula stochastic unifrom stabillty asymptotic stability
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Influence of Generalized (r, q) Distribution Function on Electrostatic Waves 被引量:2
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作者 M.N.S. Qureshi SHI Jian-Kui MA Shi-Zhuang 《Communications in Theoretical Physics》 SCIE CAS CSCD 2006年第3期550-554,共5页
Non-Maxwellian particle distribution functions possessing high energy tail and shoulder in the profile of distribution function considerably change the damping characteristics of the waves. In the present paper Landau... Non-Maxwellian particle distribution functions possessing high energy tail and shoulder in the profile of distribution function considerably change the damping characteristics of the waves. In the present paper Landau damping of electron plasma (Langmuir) waves and ion-acoustic waves in a hot, isotropic, unmagnetized plasma is studied with the generalized (r, q) distribution function. The results show that for the Langmuir oscillations Landau damping becomes severe as the spectral index r or q reduces. However, for the ion-acoustic waves Landau damping is more sensitive to the ion temperature than the spectral indices. 展开更多
关键词 generalized (r q distribution function electrostatic waves dAMPING
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A Cauchy integral formula for(p,q)-monogenic functions withα-weight
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作者 GAO Long DU Xiao-jing +1 位作者 LIU Yue XIE Yong-hong 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第3期545-553,共9页
Firstly,some properties for(p,q)-monogenic functions withα-weight in Clifford analysis are given.Then,the Cauchy-Pompeiu formula is proved.Finally,the Cauchy integral formula and the Cauchy integral theorem for(p,q)-... Firstly,some properties for(p,q)-monogenic functions withα-weight in Clifford analysis are given.Then,the Cauchy-Pompeiu formula is proved.Finally,the Cauchy integral formula and the Cauchy integral theorem for(p,q)-monogenic functions withα-weight are given. 展开更多
关键词 (p q)-monogenic functions with-weight Cauchy-Pompeiu formula Cauchy integral formula Cauchy integral theorem
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3D printing of poly(ethyleneimine)-functionalized Mg-Al mixed metal oxide monoliths for direct air capture of CO_(2)
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作者 Qingyang Shao Zhuozhen Gan +4 位作者 Bingyao Ge Xuyi Liu Chunping Chen Dermot O’Hare Xuancan Zhu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第9期491-500,共10页
Direct air capture(DAC)of CO_(2)plays an indispensable role in achieving carbon-neutral goals as one of the key negative emission technologies.Since large air flows are required to capture the ultradilute CO_(2)from t... Direct air capture(DAC)of CO_(2)plays an indispensable role in achieving carbon-neutral goals as one of the key negative emission technologies.Since large air flows are required to capture the ultradilute CO_(2)from the air,lab-synthesized adsorbents in powder form may cause unacceptable gas pressure drops and poor heat and mass transfer efficiencies.A structured adsorbent is essential for the implementation of gas-solid contactors for cost-and energy-efficient DAC systems.In this study,efficient adsorbent poly(ethyleneimine)(PEI)-functionalized Mg-Al-CO_(3)layered double hydroxide(LDH)-derived mixed metal oxides(MMOs)are three-dimensional(3D)printed into monoliths for the first time with more than 90%adsorbent loadings.The printing process has been optimized by initially printing the LDH powder into monoliths followed by calcination into MMO monoliths.This structure exhibits a 32.7%higher specific surface area and a 46.1%higher pore volume,as compared to the direct printing of the MMO powder into a monolith.After impregnation of PEI,the monolith demonstrates a large adsorption capacity(1.82 mmol/g)and fast kinetics(0.7 mmol/g/h)using a CO_(2)feed gas at 400 ppm at 25℃,one of the highest values among the shaped DAC adsorbents.Smearing of the amino-polymers during the post-printing process affects the diffusion of CO_(2),resulting in slower adsorption kinetics of pre-impregnation monoliths compared to post-impregnation monoliths.The optimal PEI/MeOH ratio for the post-impregnation solution prevents pores clogging that would affect both adsorption capacity and kinetics. 展开更多
关键词 3d printing Mixed metal oxides Amine functionalization Structured adsorbent direct air capture
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Association between hip abductor function,rear-foot dynamic alignment,and dynamic knee valgus during single-leg squats and drop landings 被引量:2
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作者 Yoshinori Kagaya Yasunari Fujii Hidetsugu Nishizono 《Journal of Sport and Health Science》 SCIE 2015年第2期182-187,共6页
Background: Preventing anterior cruciate ligament(ACL) injuries is very important for athletes, and dynamic knee valgus is considered a risk factor for non-contact ACL injury. However, little is known about whether... Background: Preventing anterior cruciate ligament(ACL) injuries is very important for athletes, and dynamic knee valgus is considered a risk factor for non-contact ACL injury. However, little is known about whether the functions of the hip abductor and rear-foot increase dynamic knee valgus. A two-dimensional(2D) video-based screening test focused on hip abductor and rear-foot functions among factors involved in dynamic knee valgus. The present study determined associations between hip and rear-foot dynamic alignment and dynamic knee valgus.Methods: This cross-sectional study recruited 130 female basketball players(258 legs) from nine high-school teams. The players performed single-leg squats and single-leg drop landings to provide knee-in(KID) and hip-out(HOD) distances on 2D video images. Hip and rear-foot dynamic alignment was evaluated using a dynamic Trendelenburg test(DTT) and a dynamic heel-floor test(HFT).Results: The Chi-square test revealed no significant difference in the prevalence of DTT-positivity between single-leg squats(28.7%) and singleleg drop landings(23.3%). The prevalence of HFT-positivity was significantly greater during landings(51.4%) than during single-leg squats(31.0%, p 〈 0.01). The KID values for both single-leg squats and single-leg drop landings were greater in the DTT-positive than in the DTTnegative group(15.1 5.4 cm and 20.2 7.5 cm, p 〈 0.001). The HOD values were similarly greater in the DTT-positive group(15.2 1.9 cm and 17.6 2.8 cm, p 〈 0.001). The KID values for both single-leg squats and single-leg drop landings were greater in the HFT-positive than in the HFT-negative group(12.2 5.1 cm, p 〈 0.01; 14.7 7.2 cm, p 〈 0.001), whereas HOD values for these tasks did not significantly differ between the two groups.Conclusion: Dynamic hip mal-alignment might be associated with both greater KID and HOD, whereas rear-foot eversion is associated only with greater KID. Hip abductor and rear-foot dysfunction are important factors for dynamic knee valgus and thus evaluating DTT and HFT will help to prevent dynamic knee valgus. 展开更多
关键词 2d screening test ACL injury dynamic alignment Hip abductor and rear-foot function Prevention
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Bowel function and quality of life after minimally invasive colectomy with D3 lymphadenectomy for right-sided colon adenocarcinoma 被引量:2
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作者 Ki-Myung Lee Se-Jin Baek +2 位作者 Jung-Myun Kwak Jin Kim Seon-Hahn Kim 《World Journal of Gastroenterology》 SCIE CAS 2020年第33期4972-4982,共11页
BACKGROUND Changes in bowel function after right-sided colectomy are not well understood compared to those associated with left-sided colectomy or rectal resection.In particular,there are concerns about bowel function... BACKGROUND Changes in bowel function after right-sided colectomy are not well understood compared to those associated with left-sided colectomy or rectal resection.In particular,there are concerns about bowel function after right-sided colectomy with complete mesocolic excision,which has become popular in the West.AIM To evaluate the functional outcomes of patients who underwent right-sided colectomy with D3 lymphadenectomy for colon cancer.METHODS Functional data from patients who underwent minimally invasive right-sided colectomy for colon cancer from October 2017 to September 2018 were prospectively collected.Functional outcomes were evaluated preoperatively and at 3,6,12,and 18 mo postoperatively.RESULTS Prior to surgery,57 patients answered the questionnaire,and 47 responded at three months,52 at 6 mo,52 at 12 mo,and 25 at 18 mo postoperatively.Most scales of quality of life and bowel function improved significantly over time.Urgency persisted to a high degree throughout the period without a significant change over time.The use of medications for defecation was about 10%over the entire period.Gas(P=0.023)and fecal frequency(P<0.001)increased,and bowel dysfunction group(P=0.028)was more common among patients taking medication.At six months,resected bowel and colon lengths were significantly different as a risk factor between the dysfunction group and the no dysfunction group[odd ratio(OR):1.095,P=0.026;OR:1.147,P=0.031,respectively]in univariate analysis,but not in multivariate analysis.CONCLUSION Despite D3 lymphadenectomy,most bowel symptoms improved over time after right-sided colectomy using a minimally invasive approach,and continuous medication was needed in only approximately 10%of patients. 展开更多
关键词 Colonic neoplasm Right colectomy Bowel function d3 lymphadenectomy Complete mesocolic excision quality of life
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q–differ-integral operator on p–valent functions associated with operator on Hilbert space 被引量:1
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作者 Shahram Najafzadeh 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2023年第3期458-466,共9页
Making use of multivalent functions with negative coefficients of the type f (z)=z^(p)-~(∑)_(k=p+1)^(∞)a_(k)z^(k),which are analytic in the open unit disk and applying the q-derivative a q–differintegral operator i... Making use of multivalent functions with negative coefficients of the type f (z)=z^(p)-~(∑)_(k=p+1)^(∞)a_(k)z^(k),which are analytic in the open unit disk and applying the q-derivative a q–differintegral operator is considered.Furthermore by using the familiar Riesz-Dunford integral,a linear operator on Hilbert space H is introduced.A new subclass of p-valent functions related to an operator on H is defined.Coefficient estimate,distortion bound and extreme points are obtained.The convolution-preserving property is also investigated. 展开更多
关键词 multivalent function fractional qderivative operator fractional q–integral operator Hilbert space coefficient estimate distortion bound extreme point convolution(or Hadamard product)
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SOME COMPLETELY MONOTONIC FUNCTIONS ASSOCIATED WITH THE q-GAMMA AND THE q-POLYGAMMA FUNCTIONS 被引量:1
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作者 Ahmed SALEM Eid S.KAMEL 《Acta Mathematica Scientia》 SCIE CSCD 2015年第5期1214-1224,共11页
In this paper, the q-analogue of the Stirling formula for the q-gamma function (Moak formula) is exploited to prove the complete monotonicity properties of some functions involving the q-gamma and the q-polygamma fu... In this paper, the q-analogue of the Stirling formula for the q-gamma function (Moak formula) is exploited to prove the complete monotonicity properties of some functions involving the q-gamma and the q-polygamma functions for all real number q 〉 0. The monotonicity of these functions is used to establish sharp inequalities for the q-gamma and the q-polygamma functions and the q-Harmonic number. Our results are shown to be a generalization of results which were obtained by Selvi and Batir [23]. 展开更多
关键词 completely monotonic functions INEqUALITIES q-gamma function q-polygammafunction
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