A method for preparing D-valine from L-valine by racemization and chemical resolution is presented. The resolving reagent, D-2,3-dibenzoyl tartaric acid was obtained by hydrolyzation of D-2,3-dibenzoyl tartaric anhydr...A method for preparing D-valine from L-valine by racemization and chemical resolution is presented. The resolving reagent, D-2,3-dibenzoyl tartaric acid was obtained by hydrolyzation of D-2,3-dibenzoyl tartaric anhydride prepared by reaction of benzoyl chloride with D-tartaric acid. DL-valine was prepared by racemization of L-valine in the presence of aldehyde in a medium of acetic acid at 100 to 110°C for 3 h. In the presence of mineral acid, reaction of D-2,3-dibenzoyl tartaric acid with DL-valine formed diastreroisomeric salts at 84 to 95°C. Salt composed of D-2,3-dibenzoyl tartaric acid and D-valine precipitated when the diastreroisomeric salts mixtures were cooled to 15°C. The salt was reacted with base giving D-valine with yield of 70% to 80% and optical purity of over 98%.展开更多
Recently,the radial point interpolation meshfree method has gained popularity owing to its advantages in large deformation and discontinuity problems,however,the accuracy of this method depends on many factors and the...Recently,the radial point interpolation meshfree method has gained popularity owing to its advantages in large deformation and discontinuity problems,however,the accuracy of this method depends on many factors and their influences are not fully investigated yet.In this work,three main factors,i.e.,the shape parameters,the influence domain size,and the nodal distribution,on the accuracy of the radial point interpolation method(RPIM)are systematically studied and conclusive results are obtained.First,the effect of shape parameters(R,q)of the multi-quadric basis function on the accuracy of RPIM is examined via global search.A new interpolation error index,closely related to the accuracy of RPIM,is proposed.The distribution of various error indexes on the R q plane shows that shape parameters q[1.2,1.8]and R[0,1.5]can give good results for general 3-D analysis.This recommended range of shape parameters is examined by multiple benchmark examples in 3D solid mechanics.Second,through numerical experiments,an average of 30 40 nodes in the influence domain of a Gauss point is recommended for 3-D solid mechanics.Third,it is observed that the distribution of nodes has significant effect on the accuracy of RPIM although it has little effect on the accuracy of interpolation.Nodal distributions with better uniformity give better results.Furthermore,how the influence domain size and nodal distribution affect the selection of shape parameters and how the nodal distribution affects the choice of influence domain size are also discussed.展开更多
The concept of word classes (parts of speech) has always generated controversy among linguists. The earlier Prescriptive and Descriptive Schools might have set the pace for this controversy but the present dilemma i...The concept of word classes (parts of speech) has always generated controversy among linguists. The earlier Prescriptive and Descriptive Schools might have set the pace for this controversy but the present dilemma is much deeper. Learners and even teachers are sometimes at quandary as to how to proof that a particular word belongs to a particular class. This is because a word may sometimes belong to several classes, in context as in the word "watch" which can belong to different classes. This paper therefore tries to provide answers to the problem of word class classification by using a morphological and syntactical evidence to prove that English words follow a particular range of inflections and belong to strictly ordered particular categories and do not change their class arbitrarily. This is in line with the natural perfect order of homogeneity in creation which precludes a specie from merging effectively with another specie without having to undergo some fundamental changes. Other variables were also looked into and it was concluded that teachers and learners as well, can rely on this sub-categorization approach as a reliable paradigm for their assumptions concerning word classes.展开更多
By utilizing a 3-D atmospheric circulation resolving method, the authors studied the air-sea interactive linkages between the tropical Indian Ocean and the Pacific Ocean in 1979-2008 E1 Nifio-Southern Oscillation (E...By utilizing a 3-D atmospheric circulation resolving method, the authors studied the air-sea interactive linkages between the tropical Indian Ocean and the Pacific Ocean in 1979-2008 E1 Nifio-Southern Oscillation (ENSO) events. Their findings showed that evident 3-D gear-coupling characteristics existed in the 1979-2008 ENSO events. Their resolving analyses also suggested that the general circulation showed stronger and wider sinking motions over the eastern Indian Ocean-western Pacific during the mature phase of 1979-2008 ENSO events, compared with the vertical velocities from the U.S. National Centers for Enviornmental Prediction (NCEP) reanalysis data. With their 3-D analysis method, the vertical velocity was resolved by two components, i.e. zonal and meridional components. It was found that the zonal component of the vertical velocities showed a strong sinking motion while the meridional components showed an upward motion during the prevailing phases of the ENSO events. In the tropics, the zonal component of the vertical velocities was found greater than the meridional component, reflecting the dominant characteristics of the vertical velocity, and the overall outcomes showed a strong sinking motion, although the two components also partially offset each other in the processes. Compared with the vertical velocities from NCEP reanalysis, the vertical motions calculated with the 3-D resolving analysis method demonstrate some advantages.展开更多
Multi-source information fusion (MSIF) is imported into structural damage diagnosis methods to improve the validity of damage detection. After the introduction of the basic theory, the function model, classification...Multi-source information fusion (MSIF) is imported into structural damage diagnosis methods to improve the validity of damage detection. After the introduction of the basic theory, the function model, classifications and mathematical methods of MSIF, a structural damage detection method based on MSIF is presented, which is to fuse two or more damage character vectors from different structural damage diagnosis methods on the character-level. In an experiment of concrete plates, modal information is measured and analyzed. The structural damage detection method based on MSIF is taken to localize cracks of concrete plates and it is proved to be effective. Results of damage detection by the method based on MSIF are compared with those from the modal strain energy method and the flexibility method. Damage, which can hardly be detected by using the single damage identification method, can be diagnosed by the damage detection method based on the character-level MSIF technique. Meanwhile multi-location damage can be identified by the method based on MSIF. This method is sensitive to structural damage and different mathematical methods for MSIF have different preconditions and applicabilities for diversified structures. How to choose mathematical methods for MSIF should be discussed in detail in health monitoring systems of actual structures.展开更多
How to obtain proper prior distribution is one of the most critical problems in Bayesian analysis. In many practical cases, the prior information often comes from different sources, and the prior distribution form cou...How to obtain proper prior distribution is one of the most critical problems in Bayesian analysis. In many practical cases, the prior information often comes from different sources, and the prior distribution form could be easily known in some certain way while the parameters are hard to determine. In this paper, based on the evidence theory, a new method is presented to fuse the information of multiple sources and determine the parameters of the prior distribution when the form is known. By taking the prior distributions which result from the information of multiple sources and converting them into corresponding mass functions which can be combined by Dempster-Shafer (D-S) method, we get the combined mass function and the representative points of the prior distribution. These points are used to fit with the given distribution form to determine the parameters of the prior distribution. And then the fused prior distribution is obtained and Bayesian analysis can be performed. How to convert the prior distributions into mass functions properly and get the representative points of the fused prior distribution is the central question we address in this paper. The simulation example shows that the proposed method is effective.展开更多
Quantum dynamics for the D+OD+ reaction at the collision energy range of 0.0-1.0 eV was studied on an accurate ab initio potential energy surface. Both of the endothermic abstraction (D+OD+-→O++D2) and thermo...Quantum dynamics for the D+OD+ reaction at the collision energy range of 0.0-1.0 eV was studied on an accurate ab initio potential energy surface. Both of the endothermic abstraction (D+OD+-→O++D2) and thermoneutral exchange (D+OD+--*D+OD+) channels were investigated from the same set of time-dependent quantum wave packets method under cen- trifugal sudden approximation. The reaction probability dependence with collision energy, the integral cross sections, and the thermal rate constant of the both channels are calculated. It is found that there is a convex structure in the reaction path of the exchange reaction. The calculated time evolution of the wave packet distribution at J=0 clearly indicates that the convex structure significantly influences the dynamics of the exchange and abstraction channels of title reaction.展开更多
AIM: To examine whether vitamin D is of potential relevance in the healing process of fractures. METHODS: The present narrative review examined the bulk of the evidence based literature on the topic of vitamin D and...AIM: To examine whether vitamin D is of potential relevance in the healing process of fractures. METHODS: The present narrative review examined the bulk of the evidence based literature on the topic of vitamin D and bone healing in key electronic data bases from 1980 onwards using the terms vitamin D and bone healing, callus, fracture healing. All data were examined carefully and categorized according to type of study. A summary of the diverse terms and approaches employed in the research, as well as the rationale for hypothesizing vitamin D has a role in fracture healing was detailed.RESULTS: The results show very few human studies have been conducted to examine if vitamin D is effective at promoting post fracture healing, and the different ani-mal models that have been studied provide no consensus on this topic. The terms used in the related literature, as well as the methods used to arrive at conclusions on this clinical issue are highly diverse, there is no standardization of either of these important terms and methodolo-gies, hence no conclusive statements or clinical guide-lines can be forthcoming. There is a strong rational for continuing to examine if vitamin D supplements should be administered post-fracture, and ample evidence vitamin D is an essential hormone for functioning in general, as well as bone health and muscle as this relates to bone density.CONCLUSION: Whether those with low vitamin D levels can beneft from supplements if their nutritional practices do not cover recommended daily amounts, remains in question.展开更多
This work was designed to study the subsurface structures in the Siwa Oasis area of the Western Desert in Egypt and to determine their effects on surface geologic structures. A detailed land magnetic survey was perfor...This work was designed to study the subsurface structures in the Siwa Oasis area of the Western Desert in Egypt and to determine their effects on surface geologic structures. A detailed land magnetic survey was performed in traverses covering about 400 km2 of the study area. The measured total magnetic field was corrected and reduced to the north magnetic pole. The reduction-to-pole aeromagnetic and Bouguer anomaly maps were used to obtain regional extensions of these subsurface structures, study the continuation of these structures in sedimentary rocks, and delineate the depths to the basement rocks. Data analysis was performed using trend analysis, Euler deconvolution, Werner deconvolution, the Hilbert transform of the analytical signal, and 3-dimensional magnetic modeling methods. The results indicate that the area is affected by tectonic forces in the E-W, N45°-65°E, and N35°-45°W trends, which are correlated with the directions of surface geologic lineaments. The depth to the basement rocks increases from 3.2 km in the southern part to about 3.6 km in the northern part of the area. The results are in good agreement with depths obtained from drill hole data in the area.展开更多
文摘A method for preparing D-valine from L-valine by racemization and chemical resolution is presented. The resolving reagent, D-2,3-dibenzoyl tartaric acid was obtained by hydrolyzation of D-2,3-dibenzoyl tartaric anhydride prepared by reaction of benzoyl chloride with D-tartaric acid. DL-valine was prepared by racemization of L-valine in the presence of aldehyde in a medium of acetic acid at 100 to 110°C for 3 h. In the presence of mineral acid, reaction of D-2,3-dibenzoyl tartaric acid with DL-valine formed diastreroisomeric salts at 84 to 95°C. Salt composed of D-2,3-dibenzoyl tartaric acid and D-valine precipitated when the diastreroisomeric salts mixtures were cooled to 15°C. The salt was reacted with base giving D-valine with yield of 70% to 80% and optical purity of over 98%.
基金Project(2010CB732103)supported by the National Basic Research Program of ChinaProject(51179092)supported by the National Natural Science Foundation of ChinaProject(2012-KY-02)supported by the State Key Laboratory of Hydroscience and Engineering,China
文摘Recently,the radial point interpolation meshfree method has gained popularity owing to its advantages in large deformation and discontinuity problems,however,the accuracy of this method depends on many factors and their influences are not fully investigated yet.In this work,three main factors,i.e.,the shape parameters,the influence domain size,and the nodal distribution,on the accuracy of the radial point interpolation method(RPIM)are systematically studied and conclusive results are obtained.First,the effect of shape parameters(R,q)of the multi-quadric basis function on the accuracy of RPIM is examined via global search.A new interpolation error index,closely related to the accuracy of RPIM,is proposed.The distribution of various error indexes on the R q plane shows that shape parameters q[1.2,1.8]and R[0,1.5]can give good results for general 3-D analysis.This recommended range of shape parameters is examined by multiple benchmark examples in 3D solid mechanics.Second,through numerical experiments,an average of 30 40 nodes in the influence domain of a Gauss point is recommended for 3-D solid mechanics.Third,it is observed that the distribution of nodes has significant effect on the accuracy of RPIM although it has little effect on the accuracy of interpolation.Nodal distributions with better uniformity give better results.Furthermore,how the influence domain size and nodal distribution affect the selection of shape parameters and how the nodal distribution affects the choice of influence domain size are also discussed.
文摘The concept of word classes (parts of speech) has always generated controversy among linguists. The earlier Prescriptive and Descriptive Schools might have set the pace for this controversy but the present dilemma is much deeper. Learners and even teachers are sometimes at quandary as to how to proof that a particular word belongs to a particular class. This is because a word may sometimes belong to several classes, in context as in the word "watch" which can belong to different classes. This paper therefore tries to provide answers to the problem of word class classification by using a morphological and syntactical evidence to prove that English words follow a particular range of inflections and belong to strictly ordered particular categories and do not change their class arbitrarily. This is in line with the natural perfect order of homogeneity in creation which precludes a specie from merging effectively with another specie without having to undergo some fundamental changes. Other variables were also looked into and it was concluded that teachers and learners as well, can rely on this sub-categorization approach as a reliable paradigm for their assumptions concerning word classes.
基金Key knowledge innovation research project (KZCX2-YW-Q11-01)973 project (2006CB403600)National Natural Science Foundation of China project (40805034)
文摘By utilizing a 3-D atmospheric circulation resolving method, the authors studied the air-sea interactive linkages between the tropical Indian Ocean and the Pacific Ocean in 1979-2008 E1 Nifio-Southern Oscillation (ENSO) events. Their findings showed that evident 3-D gear-coupling characteristics existed in the 1979-2008 ENSO events. Their resolving analyses also suggested that the general circulation showed stronger and wider sinking motions over the eastern Indian Ocean-western Pacific during the mature phase of 1979-2008 ENSO events, compared with the vertical velocities from the U.S. National Centers for Enviornmental Prediction (NCEP) reanalysis data. With their 3-D analysis method, the vertical velocity was resolved by two components, i.e. zonal and meridional components. It was found that the zonal component of the vertical velocities showed a strong sinking motion while the meridional components showed an upward motion during the prevailing phases of the ENSO events. In the tropics, the zonal component of the vertical velocities was found greater than the meridional component, reflecting the dominant characteristics of the vertical velocity, and the overall outcomes showed a strong sinking motion, although the two components also partially offset each other in the processes. Compared with the vertical velocities from NCEP reanalysis, the vertical motions calculated with the 3-D resolving analysis method demonstrate some advantages.
基金The National High Technology Research and Develop-ment Program of China(863Program)(No.2006AA04Z416)the Na-tional Science Fund for Distinguished Young Scholars(No.50725828)the Excellent Dissertation Program for Doctoral Degree of Southeast University(No.0705)
文摘Multi-source information fusion (MSIF) is imported into structural damage diagnosis methods to improve the validity of damage detection. After the introduction of the basic theory, the function model, classifications and mathematical methods of MSIF, a structural damage detection method based on MSIF is presented, which is to fuse two or more damage character vectors from different structural damage diagnosis methods on the character-level. In an experiment of concrete plates, modal information is measured and analyzed. The structural damage detection method based on MSIF is taken to localize cracks of concrete plates and it is proved to be effective. Results of damage detection by the method based on MSIF are compared with those from the modal strain energy method and the flexibility method. Damage, which can hardly be detected by using the single damage identification method, can be diagnosed by the damage detection method based on the character-level MSIF technique. Meanwhile multi-location damage can be identified by the method based on MSIF. This method is sensitive to structural damage and different mathematical methods for MSIF have different preconditions and applicabilities for diversified structures. How to choose mathematical methods for MSIF should be discussed in detail in health monitoring systems of actual structures.
文摘How to obtain proper prior distribution is one of the most critical problems in Bayesian analysis. In many practical cases, the prior information often comes from different sources, and the prior distribution form could be easily known in some certain way while the parameters are hard to determine. In this paper, based on the evidence theory, a new method is presented to fuse the information of multiple sources and determine the parameters of the prior distribution when the form is known. By taking the prior distributions which result from the information of multiple sources and converting them into corresponding mass functions which can be combined by Dempster-Shafer (D-S) method, we get the combined mass function and the representative points of the prior distribution. These points are used to fit with the given distribution form to determine the parameters of the prior distribution. And then the fused prior distribution is obtained and Bayesian analysis can be performed. How to convert the prior distributions into mass functions properly and get the representative points of the fused prior distribution is the central question we address in this paper. The simulation example shows that the proposed method is effective.
文摘Quantum dynamics for the D+OD+ reaction at the collision energy range of 0.0-1.0 eV was studied on an accurate ab initio potential energy surface. Both of the endothermic abstraction (D+OD+-→O++D2) and thermoneutral exchange (D+OD+--*D+OD+) channels were investigated from the same set of time-dependent quantum wave packets method under cen- trifugal sudden approximation. The reaction probability dependence with collision energy, the integral cross sections, and the thermal rate constant of the both channels are calculated. It is found that there is a convex structure in the reaction path of the exchange reaction. The calculated time evolution of the wave packet distribution at J=0 clearly indicates that the convex structure significantly influences the dynamics of the exchange and abstraction channels of title reaction.
文摘AIM: To examine whether vitamin D is of potential relevance in the healing process of fractures. METHODS: The present narrative review examined the bulk of the evidence based literature on the topic of vitamin D and bone healing in key electronic data bases from 1980 onwards using the terms vitamin D and bone healing, callus, fracture healing. All data were examined carefully and categorized according to type of study. A summary of the diverse terms and approaches employed in the research, as well as the rationale for hypothesizing vitamin D has a role in fracture healing was detailed.RESULTS: The results show very few human studies have been conducted to examine if vitamin D is effective at promoting post fracture healing, and the different ani-mal models that have been studied provide no consensus on this topic. The terms used in the related literature, as well as the methods used to arrive at conclusions on this clinical issue are highly diverse, there is no standardization of either of these important terms and methodolo-gies, hence no conclusive statements or clinical guide-lines can be forthcoming. There is a strong rational for continuing to examine if vitamin D supplements should be administered post-fracture, and ample evidence vitamin D is an essential hormone for functioning in general, as well as bone health and muscle as this relates to bone density.CONCLUSION: Whether those with low vitamin D levels can beneft from supplements if their nutritional practices do not cover recommended daily amounts, remains in question.
文摘This work was designed to study the subsurface structures in the Siwa Oasis area of the Western Desert in Egypt and to determine their effects on surface geologic structures. A detailed land magnetic survey was performed in traverses covering about 400 km2 of the study area. The measured total magnetic field was corrected and reduced to the north magnetic pole. The reduction-to-pole aeromagnetic and Bouguer anomaly maps were used to obtain regional extensions of these subsurface structures, study the continuation of these structures in sedimentary rocks, and delineate the depths to the basement rocks. Data analysis was performed using trend analysis, Euler deconvolution, Werner deconvolution, the Hilbert transform of the analytical signal, and 3-dimensional magnetic modeling methods. The results indicate that the area is affected by tectonic forces in the E-W, N45°-65°E, and N35°-45°W trends, which are correlated with the directions of surface geologic lineaments. The depth to the basement rocks increases from 3.2 km in the southern part to about 3.6 km in the northern part of the area. The results are in good agreement with depths obtained from drill hole data in the area.