Liver metastases and hepatocellular carcinomas are two of the most common causes of cancer deaths in the world.Radiofrequency ablation(RFA) is a well recognized,effective and minimally invasive means of treating malig...Liver metastases and hepatocellular carcinomas are two of the most common causes of cancer deaths in the world.Radiofrequency ablation(RFA) is a well recognized,effective and minimally invasive means of treating malignant hepatic tumors.This article describes the use of contrast-enhanced 3D ultrasound(CE-3DUS) in the staging,targeting and follow-up of patients with liver tumors undergoing RFA.In particular,its value in the management of large hepatic lesions will be illustrated.Current limitations of CE-3DUS and future developments in the technique will also be discussed.In summary,CE-3DUS is useful in the RFA of liver tumors with improved detection and display of occult lesions and recurrence,in the assessment of lesional geometry and orientation for a more accurate planning and guidance of multiple RFA needle electrodes in large tumors and in the evaluation of residual or recurrent disease within the immediate and/or subsequent follow-up periods.展开更多
Purpose: This review examines the diagnostic value of transvaginal 3D ultrasound image texture analysis for the diagnosis of uterine adhesions. Materials and Methods: The total clinical data of 53 patients with uterin...Purpose: This review examines the diagnostic value of transvaginal 3D ultrasound image texture analysis for the diagnosis of uterine adhesions. Materials and Methods: The total clinical data of 53 patients with uterine adhesions diagnosed by hysteroscopy and the imaging data of transvaginal three-dimensional ultrasound from the Second Affiliated Hospital of Chongqing Medical University from June 2022 to August 2023 were retrospectively analysed. Based on hysteroscopic surgical records, patients were divided into two independent groups: normal endometrium and uterine adhesion sites. The samples were divided into a training set and a test set, and the transvaginal 3D ultrasound was used to outline the region of interest (ROI) and extract texture features for normal endometrium and uterine adhesions based on hysteroscopic surgical recordings, the training set data were feature screened and modelled using lasso regression and cross-validation, and the diagnostic efficacy of the model was assessed by applying the subjects’ operating characteristic (ROC) curves. Results: For each group, 290 texture feature parameters were extracted and three higher values were screened out, and the area under the curve of the constructed ultrasonographic scoring model was 0.658 and 0.720 in the training and test sets, respectively. Conclusion Relative clinical value of transvaginal three-dimensional ultrasound image texture analysis for the diagnosis of uterine adhesions.展开更多
Background Deep convolutional neural networks have garnered considerable attention in numerous machine learning applications,particularly in visual recognition tasks such as image and video analyses.There is a growing...Background Deep convolutional neural networks have garnered considerable attention in numerous machine learning applications,particularly in visual recognition tasks such as image and video analyses.There is a growing interest in applying this technology to diverse applications in medical image analysis.Automated three dimensional Breast Ultrasound is a vital tool for detecting breast cancer,and computer-assisted diagnosis software,developed based on deep learning,can effectively assist radiologists in diagnosis.However,the network model is prone to overfitting during training,owing to challenges such as insufficient training data.This study attempts to solve the problem caused by small datasets and improve model detection performance.Methods We propose a breast cancer detection framework based on deep learning(a transfer learning method based on cross-organ cancer detection)and a contrastive learning method based on breast imaging reporting and data systems(BI-RADS).Results When using cross organ transfer learning and BIRADS based contrastive learning,the average sensitivity of the model increased by a maximum of 16.05%.Conclusion Our experiments have demonstrated that the parameters and experiences of cross-organ cancer detection can be mutually referenced,and contrastive learning method based on BI-RADS can improve the detection performance of the model.展开更多
Mild adolescent idiopathic scoliosis(AIS),with Cobb<20°,was hypothesized as the right stage to intervene to prevent progression.AIS curve can be categorized into either structural or non-structural depending o...Mild adolescent idiopathic scoliosis(AIS),with Cobb<20°,was hypothesized as the right stage to intervene to prevent progression.AIS curve can be categorized into either structural or non-structural depending on the spine morphology(flexibility).Using X-ray to characterize AIS curves remains the clinical gold standard whilecompromising the risks of radiation exposure.In previous works,3D ultrasound imaging had proved the reli-ability of the coronal spinal curvature measurement This research aimed at developing a mild AIs clasificationscheme through examining spine flexibility using 3D ultrasound imaging.For the preliminary study,90 mild AIS subjects(21 M and 69 F;Age:14.5±1.7 years old;Cobb:18.2±6.4°)underwent both 3D ultrasound and X-ray scanning on the same day.For each case,a clinician measured Cobbs and denoted major curve as ground truth.Bending Asymmetry Index(BAl)was developed to indicate the presence of a possible structural curve.The curve classification was coded to a modfied Lenke classification for mild cases(m-Lenke).The results of 3D ultrasound classification were evaluated with the X-ray.It was shown that 70.1%of the subjects had identical curve clssification results and 72.0%had the correct major curve detection.Lumbar-dominated curves had distinctive performance(p=0.91,r=0.91)against others.The study demonstrated the possibility of a 3D ultrasound-based method for mild AIS curve classification.Thediscrepancies could be partially explained by the limitations of the ultrasound scanning in proximal thoracicreg ion.Subsequent studies will validate the proposed method with a larger cohort.展开更多
<strong>Background:</strong><span style="font-family:Verdana;"> Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA)</span><span style="font-family:""><...<strong>Background:</strong><span style="font-family:Verdana;"> Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA)</span><span style="font-family:""><span style="font-family:Verdana;"> syndrome is a rare congenital condition of the female urogenital tract, presenting intraoperative challenges. We demonstrate the utility of three dimensional intraoperative ultrasound to better delineate anatomy and aid in optimal resection of the vaginal septum. </span><b><span style="font-family:Verdana;">Case:</span></b><span style="font-family:Verdana;"> A 12-year-old female was referred to pediatric and adolescent gynecology for irregular periods and evaluation of her gynecologic organs. Imaging studies confirmed OHVIRA syndrome. She underwent uncomplicated vaginal septum resection, guided by three dimensional intraoperative ultrasound. </span><b><span style="font-family:Verdana;">Summary and Conclusion:</span></b><span style="font-family:Verdana;"> Intraoperative ultrasound can better delineate challenging anatomy. We show that three dimensional intraoperative ultrasound offers significant advantages over traditional two dimensional ultrasound and is a supplement to MRI, which may be helpful in complex anatomical cases like OHVIRA syndrome.</span></span>展开更多
目的探讨超声脐血流收缩末期峰值(S)与舒张末期峰值(D)的比值(S/D)联合血清可溶性CD40配体(sCD40L)、热休克蛋白70(HSP70)对妊娠期高血压母婴结局的预测价值。方法回顾性分析2020年6月至2022年6月于保定第一中心医院诊治的160例妊娠期...目的探讨超声脐血流收缩末期峰值(S)与舒张末期峰值(D)的比值(S/D)联合血清可溶性CD40配体(sCD40L)、热休克蛋白70(HSP70)对妊娠期高血压母婴结局的预测价值。方法回顾性分析2020年6月至2022年6月于保定第一中心医院诊治的160例妊娠期高血压患者临床资料。根据母婴结局将患者分为母婴结局正常组(n=120)和母婴结局异常组(n=40)。所有患者均行超声检查脐血流S/D比值;酶联免疫吸附(ELISA)法测定患者血清中sCD40L、HSP70水平;对影响妊娠期高血压母婴结局的因素进行Logistic回归分析;受试者工作特征(ROC)曲线分析超声脐血流S/D比值联合血清sCD40L、HSP70对妊娠期高血压母婴结局的预测价值。结果与母婴结局正常组比较,异常组妊娠期高血压患者超声脐血流S/D比值显著升高(3.86±1.01 vs 2.57±0.65,P<0.05),血清sCD40L[(3.65±0.91)ng/L vs(6.04±1.42)ng/L]、HSP70水平[(2.01±0.46)μg/L vs(2.90±0.52)μg/L]均明显升高(P<0.05);Logistic回归分析发现,超声脐血流S/D比值、sCD40L、HSP70是影响妊娠期高血压患者母婴结局的危险因素(P<0.05)。超声脐血流S/D比值联合血清sCD40L、HSP70预测妊娠期高血压母婴结局的ROC曲线下面积(AUC)为0.993,均优于其各自单独预测(Z三者联合-超声脐血流S/D比值=4.030,P<0.001;Z三者联合-sCD40L=2.409,P=0.008;Z三者联合-HSP70=4.302,P<0.001)。结论妊娠期高血压患者超声脐血流S/D比值、血清sCD40L、HSP70水平升高,且与母婴结局有关,临床可用以预测患者母婴结局。展开更多
Gastric accommodation is important for the understanding of the pathophysiology in functional dyspepsia and is also relevant for symptom generation in other disorders. The term gastric accommodation has at least three...Gastric accommodation is important for the understanding of the pathophysiology in functional dyspepsia and is also relevant for symptom generation in other disorders. The term gastric accommodation has at least three different meanings： The accommodation process, the accommodation reflex, and the accommodation response. The gastric accommodation process is a complex phenomenon that describes how the size of the gastric compartment changes in response to a meal. The electronic barostat is considered the gold standard in assessing gastric accommodation. Imaging methods, including MRI, SPECT, and ultrasonography may also be used, particularly in patients who are stress-responsive, e.g. functional dyspepsia patients, as a non-invasive and less stress-inducing method is favourable. Ultrasonography satisfies these criteria as it does not by itself distort the physiological response in stress-responsive individuals.展开更多
文摘Liver metastases and hepatocellular carcinomas are two of the most common causes of cancer deaths in the world.Radiofrequency ablation(RFA) is a well recognized,effective and minimally invasive means of treating malignant hepatic tumors.This article describes the use of contrast-enhanced 3D ultrasound(CE-3DUS) in the staging,targeting and follow-up of patients with liver tumors undergoing RFA.In particular,its value in the management of large hepatic lesions will be illustrated.Current limitations of CE-3DUS and future developments in the technique will also be discussed.In summary,CE-3DUS is useful in the RFA of liver tumors with improved detection and display of occult lesions and recurrence,in the assessment of lesional geometry and orientation for a more accurate planning and guidance of multiple RFA needle electrodes in large tumors and in the evaluation of residual or recurrent disease within the immediate and/or subsequent follow-up periods.
文摘Purpose: This review examines the diagnostic value of transvaginal 3D ultrasound image texture analysis for the diagnosis of uterine adhesions. Materials and Methods: The total clinical data of 53 patients with uterine adhesions diagnosed by hysteroscopy and the imaging data of transvaginal three-dimensional ultrasound from the Second Affiliated Hospital of Chongqing Medical University from June 2022 to August 2023 were retrospectively analysed. Based on hysteroscopic surgical records, patients were divided into two independent groups: normal endometrium and uterine adhesion sites. The samples were divided into a training set and a test set, and the transvaginal 3D ultrasound was used to outline the region of interest (ROI) and extract texture features for normal endometrium and uterine adhesions based on hysteroscopic surgical recordings, the training set data were feature screened and modelled using lasso regression and cross-validation, and the diagnostic efficacy of the model was assessed by applying the subjects’ operating characteristic (ROC) curves. Results: For each group, 290 texture feature parameters were extracted and three higher values were screened out, and the area under the curve of the constructed ultrasonographic scoring model was 0.658 and 0.720 in the training and test sets, respectively. Conclusion Relative clinical value of transvaginal three-dimensional ultrasound image texture analysis for the diagnosis of uterine adhesions.
基金Macao Polytechnic University Grant(RP/FCSD-01/2022RP/FCA-05/2022)Science and Technology Development Fund of Macao(0105/2022/A).
文摘Background Deep convolutional neural networks have garnered considerable attention in numerous machine learning applications,particularly in visual recognition tasks such as image and video analyses.There is a growing interest in applying this technology to diverse applications in medical image analysis.Automated three dimensional Breast Ultrasound is a vital tool for detecting breast cancer,and computer-assisted diagnosis software,developed based on deep learning,can effectively assist radiologists in diagnosis.However,the network model is prone to overfitting during training,owing to challenges such as insufficient training data.This study attempts to solve the problem caused by small datasets and improve model detection performance.Methods We propose a breast cancer detection framework based on deep learning(a transfer learning method based on cross-organ cancer detection)and a contrastive learning method based on breast imaging reporting and data systems(BI-RADS).Results When using cross organ transfer learning and BIRADS based contrastive learning,the average sensitivity of the model increased by a maximum of 16.05%.Conclusion Our experiments have demonstrated that the parameters and experiences of cross-organ cancer detection can be mutually referenced,and contrastive learning method based on BI-RADS can improve the detection performance of the model.
基金This study is partially supported by Research Impact Fund of Hong Kong Research Grant Council(R5017-18)Health and Medical Research Fund of the Hong Kong(04152896).
文摘Mild adolescent idiopathic scoliosis(AIS),with Cobb<20°,was hypothesized as the right stage to intervene to prevent progression.AIS curve can be categorized into either structural or non-structural depending on the spine morphology(flexibility).Using X-ray to characterize AIS curves remains the clinical gold standard whilecompromising the risks of radiation exposure.In previous works,3D ultrasound imaging had proved the reli-ability of the coronal spinal curvature measurement This research aimed at developing a mild AIs clasificationscheme through examining spine flexibility using 3D ultrasound imaging.For the preliminary study,90 mild AIS subjects(21 M and 69 F;Age:14.5±1.7 years old;Cobb:18.2±6.4°)underwent both 3D ultrasound and X-ray scanning on the same day.For each case,a clinician measured Cobbs and denoted major curve as ground truth.Bending Asymmetry Index(BAl)was developed to indicate the presence of a possible structural curve.The curve classification was coded to a modfied Lenke classification for mild cases(m-Lenke).The results of 3D ultrasound classification were evaluated with the X-ray.It was shown that 70.1%of the subjects had identical curve clssification results and 72.0%had the correct major curve detection.Lumbar-dominated curves had distinctive performance(p=0.91,r=0.91)against others.The study demonstrated the possibility of a 3D ultrasound-based method for mild AIS curve classification.Thediscrepancies could be partially explained by the limitations of the ultrasound scanning in proximal thoracicreg ion.Subsequent studies will validate the proposed method with a larger cohort.
文摘<strong>Background:</strong><span style="font-family:Verdana;"> Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA)</span><span style="font-family:""><span style="font-family:Verdana;"> syndrome is a rare congenital condition of the female urogenital tract, presenting intraoperative challenges. We demonstrate the utility of three dimensional intraoperative ultrasound to better delineate anatomy and aid in optimal resection of the vaginal septum. </span><b><span style="font-family:Verdana;">Case:</span></b><span style="font-family:Verdana;"> A 12-year-old female was referred to pediatric and adolescent gynecology for irregular periods and evaluation of her gynecologic organs. Imaging studies confirmed OHVIRA syndrome. She underwent uncomplicated vaginal septum resection, guided by three dimensional intraoperative ultrasound. </span><b><span style="font-family:Verdana;">Summary and Conclusion:</span></b><span style="font-family:Verdana;"> Intraoperative ultrasound can better delineate challenging anatomy. We show that three dimensional intraoperative ultrasound offers significant advantages over traditional two dimensional ultrasound and is a supplement to MRI, which may be helpful in complex anatomical cases like OHVIRA syndrome.</span></span>
文摘目的探讨超声脐血流收缩末期峰值(S)与舒张末期峰值(D)的比值(S/D)联合血清可溶性CD40配体(sCD40L)、热休克蛋白70(HSP70)对妊娠期高血压母婴结局的预测价值。方法回顾性分析2020年6月至2022年6月于保定第一中心医院诊治的160例妊娠期高血压患者临床资料。根据母婴结局将患者分为母婴结局正常组(n=120)和母婴结局异常组(n=40)。所有患者均行超声检查脐血流S/D比值;酶联免疫吸附(ELISA)法测定患者血清中sCD40L、HSP70水平;对影响妊娠期高血压母婴结局的因素进行Logistic回归分析;受试者工作特征(ROC)曲线分析超声脐血流S/D比值联合血清sCD40L、HSP70对妊娠期高血压母婴结局的预测价值。结果与母婴结局正常组比较,异常组妊娠期高血压患者超声脐血流S/D比值显著升高(3.86±1.01 vs 2.57±0.65,P<0.05),血清sCD40L[(3.65±0.91)ng/L vs(6.04±1.42)ng/L]、HSP70水平[(2.01±0.46)μg/L vs(2.90±0.52)μg/L]均明显升高(P<0.05);Logistic回归分析发现,超声脐血流S/D比值、sCD40L、HSP70是影响妊娠期高血压患者母婴结局的危险因素(P<0.05)。超声脐血流S/D比值联合血清sCD40L、HSP70预测妊娠期高血压母婴结局的ROC曲线下面积(AUC)为0.993,均优于其各自单独预测(Z三者联合-超声脐血流S/D比值=4.030,P<0.001;Z三者联合-sCD40L=2.409,P=0.008;Z三者联合-HSP70=4.302,P<0.001)。结论妊娠期高血压患者超声脐血流S/D比值、血清sCD40L、HSP70水平升高,且与母婴结局有关,临床可用以预测患者母婴结局。
文摘Gastric accommodation is important for the understanding of the pathophysiology in functional dyspepsia and is also relevant for symptom generation in other disorders. The term gastric accommodation has at least three different meanings： The accommodation process, the accommodation reflex, and the accommodation response. The gastric accommodation process is a complex phenomenon that describes how the size of the gastric compartment changes in response to a meal. The electronic barostat is considered the gold standard in assessing gastric accommodation. Imaging methods, including MRI, SPECT, and ultrasonography may also be used, particularly in patients who are stress-responsive, e.g. functional dyspepsia patients, as a non-invasive and less stress-inducing method is favourable. Ultrasonography satisfies these criteria as it does not by itself distort the physiological response in stress-responsive individuals.
