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3D Design and Analysis of Crushing Roller of High-pressure Grinding Roller
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作者 GAO Hang 1, QU Li-gang 2 (1. School of Mechanical Engineering and Automation, Northeastern University, Shenyang 110004, China 2. Department of Mechanical Engineering, Shenyang Institute of Aeronautical Engineering, Shenyang 110034, China) 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2002年第S1期158-,共1页
Crushing roller is one of the main parts of High-p re ssure Grinding Roller, which is a kind of high efficient ore crushing equipment. A kind of assembled roller, which is more convenient to renovate worn surface b y ... Crushing roller is one of the main parts of High-p re ssure Grinding Roller, which is a kind of high efficient ore crushing equipment. A kind of assembled roller, which is more convenient to renovate worn surface b y simply replacing segmented surface of the roller, was developed. The structura l models of assembled roller’s components were designed with SolidWorks softwar e based on feature modeling, these solid models of the roller were virtually ass embled. Through this work, not only was the assemble interference checked out so as to examine validity of the structure design, but also these solid models cou ld be recognized by COSMOS/Works software, through which the finite element an alysis can be done. Then the stress and displacement of the main shaft and sur face segment in two different working states were analyzed and detected quickly according to the analysis results with COSMOS/Works. In conclusion, the optimum clearance of 1.0~2.0 mm between concave-convex studded segments is determined to make the using life of assembled roller longer. 展开更多
关键词 high-pressure grinding roller 3d design assemb led roller finite element analysis
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A VIRTUAL MESH METHOD FOR THE OPTIMIZED DESIGN OF COMPLEX STRUCTURES
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作者 Du Taisheng Huang Rongjie Song Tianxia Chen Chuanyao (College of Civil Engineering and Mechanics,Huazhong University of Science and Technology,Wuhan 430074,China) 《Acta Mechanica Solida Sinica》 SCIE EI 2003年第3期220-230,共11页
Concepts for a virtual 3D space and a hyper-sphere are proposed and the formulae for determining the computable nodes of the mesh are derived.Then a new optimization design method('Virtual Mesh Method'or V.M.M... Concepts for a virtual 3D space and a hyper-sphere are proposed and the formulae for determining the computable nodes of the mesh are derived.Then a new optimization design method('Virtual Mesh Method'or V.M.M)is developed.Three examples are given,showing that the method proposed is especially suitable for the optimized design of complex structures,and that the global approximate optimal solution can be searched with remarkably reduced computational work. 展开更多
关键词 virtual 3d space computable nodes n-d hyper-sphere optimization design virtual mesh method
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基于Design-Expert优化一款中药空气抑菌剂配方的研究
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作者 黄晓珊 王亚琴 +5 位作者 卢佳佳 曾俊棠 黄烁 范宇梦 吕立铭 李大炜 《江西化工》 CAS 2024年第1期63-67,共5页
目的:以多种中药挥发油作为原料,开发一款高效广谱抑菌的空气抑菌剂。方法:选取丁香、艾叶、香茅3种挥发油,采用Design-Expert 12.0中自带的Optimal(custom)试验设计进行最优混料配方筛选试验。通过采样我校饭堂空间空气浮游菌,先按软... 目的:以多种中药挥发油作为原料,开发一款高效广谱抑菌的空气抑菌剂。方法:选取丁香、艾叶、香茅3种挥发油,采用Design-Expert 12.0中自带的Optimal(custom)试验设计进行最优混料配方筛选试验。通过采样我校饭堂空间空气浮游菌,先按软件设计配方加样抑菌孵育并计数,再拟合出孵育菌落数与各挥发油配方比例的模型方程,最后计算出最佳抑菌效能配方比例,并采用实验室试验和现场试验验证优选配方。结果:利用286组抑菌孵育数据计算得出,孵育菌落数(Y)与各挥发油配方比例之间的拟合方程为Y=17.60A+53.01B+36.76C-106.11AB-84.87AC-63.93BC+782.79A^(2)BC-1178.89AB^(2)C+413.15ABC2。丁香与艾叶、香茅挥发油抑菌的交互作用对孵育菌落数量有显著影响(p<0.05)。最终选择的丁香、艾叶、香茅挥发油比例为45.2:41.6:13.2,该配方的实验室试验和现场试验验证了其抑菌效能良好。结论:中药抑菌挥发油复配后具有明显的增效作用。该配方的空气抑菌剂抑菌效果明显,气味芳香易于被人们接受,具有良好的市场前景和推广价值。 展开更多
关键词 中药挥发油 空气抑菌剂 最优混料设计 抑菌试验
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A Design Philosophy From the View of Creation:Design vs.Research
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作者 Fred Y.Ye 《Journal of Philosophy Study》 2021年第12期942-948,共7页
Mankind holds creation as a special human property contributing knowledge and culture.Both design and research belong to creative activities.While research focuses on new findings following the rule of truth,design pa... Mankind holds creation as a special human property contributing knowledge and culture.Both design and research belong to creative activities.While research focuses on new findings following the rule of truth,design pays more attention to new designed works following the rule of beauty.Three philosophical principles for design are suggested as ABC principles:A.Design approaches beauty;B.Design balances science and art;C.Design concerns culture.Three types of design are practically discussed,including 2D art or symbol design,3D engineering or product design,and nD program or form design. 展开更多
关键词 RESEARCH design 2d design 3d design art design engineering design hard design soft design CREATION
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D-最优混料设计制备青藤碱微乳及其药效学初步考察
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作者 高勤 陈楠 +4 位作者 贾乐彤 汪洁 陈静 杨雨微 吕志阳 《南京中医药大学学报》 CAS CSCD 北大核心 2024年第4期391-398,共8页
目的优化青藤碱微乳的制备工艺,进行初步药效学评价。方法建立青藤碱的HPLC含量测定方法,通过溶解度实验及伪三元相图等初步筛选青藤碱微乳处方,利用D-最优混料实验设计法以粒径和载药量为考察指标进行青藤碱微乳处方优化,并对其粒径、... 目的优化青藤碱微乳的制备工艺,进行初步药效学评价。方法建立青藤碱的HPLC含量测定方法,通过溶解度实验及伪三元相图等初步筛选青藤碱微乳处方,利用D-最优混料实验设计法以粒径和载药量为考察指标进行青藤碱微乳处方优化,并对其粒径、载药量及稳定性等进行评价;采用体外透皮实验考察经皮吸收情况,进行耳肿胀实验评价抗炎药效。结果以甲醇∶0.1%磷酸(40∶60)为流动相,检测波长为262 nm测定青藤碱含量,方法适用性好;获得微乳最佳处方为蓖麻油占比7.0%,PEG40氢化蓖麻油/无水乙醇为混合乳化剂占比69.0%,最佳Km值为3∶1,蒸馏水占比24.0%;制得微乳平均粒径18.76 nm,PDI为0.072,载药量5.225%;1.0%青藤碱微乳12 h累积渗透量为1.2234μg·cm^(-2),稳态渗透速率为0.0649μg·cm^(-2)·h^(-1),均优于青藤碱溶液;高浓度的青藤碱微乳对小鼠耳肿胀抑制率为65.07%,与阳性药地塞米松效果相近。结论制得青藤碱微乳工艺稳定,载药量高,透皮吸收及抗炎效果较好,为青藤碱经皮给药制剂开发提供参考。 展开更多
关键词 青藤碱 微乳 伪三元相图 d-最优混料设计 药效学
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基于遗传算法优化的风洞试验MDOE方法
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作者 江嘉伟 程起有 +2 位作者 樊枫 陈卫星 汪文涛 《直升机技术》 2024年第1期63-68,共6页
为提高风洞试验效率,现代试验设计(MDOE)方法正越来越频繁地用于各类飞行器风洞试验。然而,基于MDOE方法的风洞试验尽管理论上减少了试验点数量,有效缩短了风洞吹风时间,但也带来了试验数据精度下降的问题。为此发展了一种基于D-最优设... 为提高风洞试验效率,现代试验设计(MDOE)方法正越来越频繁地用于各类飞行器风洞试验。然而,基于MDOE方法的风洞试验尽管理论上减少了试验点数量,有效缩短了风洞吹风时间,但也带来了试验数据精度下降的问题。为此发展了一种基于D-最优设计准则和二元三次多项式响应面模型的MDOE方法,同时引入遗传算法进一步提高响应面模型的拟合精度。结果表明,所开发的MDOE风洞试验方法仅需单变量(OFAT)方法30%左右的试验点数,吹风时间较OFAT方法大约缩短了60%;与最初拟合的多项式响应面模型相比,遗传算法优化后的响应面拟合精度提高了5%左右,内插得到的数据误差更小。 展开更多
关键词 d-最优设计准则 多项式响应面模型 MdOE 风洞试验
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基于D-最优混料设计优选益气固表速溶散处方及评价
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作者 辛二旦 于小刚 +5 位作者 李东辉 杨新荣 燕玉奎 靳子明 杨锡仓 张兆芳 《辽宁中医药大学学报》 CAS 2024年第5期37-42,共6页
目的综合中药粉体改性技术、矫味技术和原料药前处理技术制备益气固表速溶散,并进行处方优选及评价,解决儿童给药困难的问题。方法在单因素实验的基础上,以流出速度、休止角、吸湿率、粒径分布宽度为评价指标,采用D-最优混料设计优选益... 目的综合中药粉体改性技术、矫味技术和原料药前处理技术制备益气固表速溶散,并进行处方优选及评价,解决儿童给药困难的问题。方法在单因素实验的基础上,以流出速度、休止角、吸湿率、粒径分布宽度为评价指标,采用D-最优混料设计优选益气固表速溶散的最佳处方,并通过物理指纹图谱、粉体学性质、口感评价和红外光谱等方法对益气固表速溶散及传统散剂进行评价。结果益气固表速溶散的最佳处方为药辅比5∶1,混料蔗糖-饴糖-柠檬酸比12∶12∶1;3批样品物理指纹图谱相似度均大于0.997,表明3批速溶散的物理质量一致;速溶散和传统散之间的相似度仅为0.129,表明其粉体学性质差异较大,其物理属性有所差异;益气固表速溶散与普通散的粉体学性质及口感存在差异,且速溶散优于传统散;两种散剂的红外光谱基本一致,表明其化学成分结构未发生明显变化。结论益气固表速溶散研制开发能更好地提高儿童用药依从性,为中医临床提供“良药可口”的新选择。 展开更多
关键词 益气固表速溶散 d-最优混料设计 物理指纹图谱 口感评价 红外光谱
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昌图县D级GNSS控制网优化设计与建立
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作者 蒋欣 《测绘与空间地理信息》 2024年第6期151-154,共4页
昌图县自然资源局在2021年2—12月组织开展了D级GNSS控制网布测及坐标参数转换项目。通过该项目的探索实施,总结出了大区域控制网优化设计及建立的途径和方法;通过坐标系间转换关系的研究,实现了各种基准成果之间精准的相互转换,满足了... 昌图县自然资源局在2021年2—12月组织开展了D级GNSS控制网布测及坐标参数转换项目。通过该项目的探索实施,总结出了大区域控制网优化设计及建立的途径和方法;通过坐标系间转换关系的研究,实现了各种基准成果之间精准的相互转换,满足了昌图县各行业对基础测绘成果及转换的需求。 展开更多
关键词 d级GNSS控制网 优化设计 坐标转换
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含噻吩并[3,2-d]嘧啶的查尔酮类化合物的合成及其抗增殖活性
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作者 黄婷 孙安霞 +1 位作者 崔益铭 张浩阳 《精细化工》 EI CAS CSCD 北大核心 2024年第2期427-432,共6页
运用药物分子片段原理及拼合原理,设计并以70.1%~83.9%的收率合成了10个含噻吩并[3,2-d]嘧啶的查尔酮类衍生物,并对该类化合物的体外抗肿瘤细胞增殖活性进行初步研究。通过1HNMR、13CNMR和HRMS(ESI)确证了目标化合物的结构。以人肺腺癌... 运用药物分子片段原理及拼合原理,设计并以70.1%~83.9%的收率合成了10个含噻吩并[3,2-d]嘧啶的查尔酮类衍生物,并对该类化合物的体外抗肿瘤细胞增殖活性进行初步研究。通过1HNMR、13CNMR和HRMS(ESI)确证了目标化合物的结构。以人肺腺癌细胞株A549、人肝癌细胞株HepG2和人前列腺癌细胞株PC-33种肿瘤细胞为测试细胞株,采用四甲基偶氮唑盐(MTT)法评价了目标化合物的抗增殖活性。结果表明,10个化合物对3种肿瘤细胞株均具有很好的抑制活性。其中,3-{4-[4-(2-氯噻吩并[3,2-d]嘧啶-4-基)哌嗪-1-羰基]苯基}-1-(3,4-二甲氧基苯基)丙基-2-烯-1-酮(Ⅶh)活性突出,对A549、HepG2和PC-33种肿瘤细胞株的半抑制浓度(IC_(50))分别为(0.87±0.05)、(2.43±0.16)和(2.02±0.10)μmol/L,优于阳性对照药索拉非尼。 展开更多
关键词 药物分子设计 查尔酮 噻吩并[3 2-d]嘧啶 合成 抗增殖活性 医药与日化原料
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4D Design and Simulation Technologies and Process Design Patterns to Support Lean Construction Methods 被引量:2
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作者 Manfred Breit Manfred Vogel +2 位作者 Fritz Hubi Fabian Mrki Micheal Raps 《Tsinghua Science and Technology》 SCIE EI CAS 2008年第S1期179-184,共6页
The objective of this ongoing joint research program is to determine how 3D/4D modeling, simulation and visualization of Products (buildings), Organizations and Processes (POP) can support lean construction. Initial f... The objective of this ongoing joint research program is to determine how 3D/4D modeling, simulation and visualization of Products (buildings), Organizations and Processes (POP) can support lean construction. Initial findings suggest that Process Design Pattern may have the potential to intuitively support ICT based lean construction. We initiated a 'Process Archeology' in order to reveal the requirements for tools that can support the planning, simulation and control of lean construction methods. First findings show that existing tools provide only limited support and therefore, we started to develop new methodologies and technologies to overcome these shortcomings. Through the introduction of Process Design Patterns, we intent to establish process thinking in the interdisciplinary POP design. Optimized construction processes may be synthesized with semi-automatic methods by applying Process Design Patterns on building structures. By providing process templates that integrate problem solution and expert knowledge, Process Design Patterns may have the potential to ensure high quality process models. 展开更多
关键词 4d design process and organization modeling and simulation process design patterns lean construction methods
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Development of the 3D-Designed Lathe Fixture of a Float Brake Caliper 被引量:1
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作者 PAN Jin-kun ZUO Wan-li LU Dong-sheng 《International Journal of Plant Engineering and Management》 2010年第4期247-250,共4页
According to the technique requests of the brake caliper in the process of production, a special fixture of float brake caliper has been developed based on 3 D design in this paper. The development process and verifie... According to the technique requests of the brake caliper in the process of production, a special fixture of float brake caliper has been developed based on 3 D design in this paper. The development process and verified data from 3D modeling and kinematics simulation for this special fixture show that this 3D-designed process can conveniently forecast the assembly interference of the fixture and accurately add the mass of lead brick before the prototype is made. In this way the flutter caused by the unbalanced lathe fixture can be eliminated and the precision of run-out tolerance in cylinder hole compared with machine tool spindle can be improved, thus the processing quality of the cylinder hole in a brake caliper can be greatly guaranteed. 展开更多
关键词 3d design brake calipers lathe fixture
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First application of 3D design custom-made uncemented prosthetic stem for distal femoral cemented megaprosthesis revision
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作者 Li Min Kai Yao +7 位作者 Minxun Lu Yong Zhou Jie Wang Fan Tang Wenli Zhang Yi Luo Hong Duan Chongqi Tu 《Precision Clinical Medicine》 2018年第2期88-96,共9页
Objectives:3D design,which is widely used in orthopedics,can be applied for precise distal femoral megaprosthetic revision.This research aimed to present and evaluate the design,perioperative management,and midterm cl... Objectives:3D design,which is widely used in orthopedics,can be applied for precise distal femoral megaprosthetic revision.This research aimed to present and evaluate the design,perioperative management,and midterm clinical outcomes of a 3D design custom-made uncemented prosthetic stem.Methods:Between January 2014 and January 2016,seven patients received 3D design custom-made uncemented prosthetic stem revision at our institution.Clinical records and radiographs were evaluated retrospectively.Results:There were no hardware-related complications during the follow-up(average 24.3 months;range 24–48 months).The average Musculoskeletal Tumor Society(MSTS)score at the last follow-up after revision(27.7 points,range 25–28 points)was significantly higher than that before(16.0 points,range 13–18 points).In addition,the range of motion(ROM)of the affected knee,and the scores of pain,function,emotional acceptance,support,walking and gait all improved significantly.The antecurvature radian of the revision stem averaged at 3.6°.Of the seven patients,three received femoral stem revision and four received revision of the femoral stem and the femoral component;three of them used longer prostheses than the others.There were no significant differences in function between these two groups at the last follow-up after revision.Conclusion:The 3D design custom-made prosthesis is a typical precision medicine technology in oncologic orthopedics.Characterized by its individually and precisely designed uncemented stem,it offers an alternative option for distal femoral cemented prosthesis revision.Besides the 3D design itself,the perioperative management,especially the techniques for stem implantation,and long-term follow-up are also crucial. 展开更多
关键词 distal femur bone tumor 3d design prosthetic stem REVISION precision medicine
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工科专业课堂“3D(Debate/Design/Doing)”教学法研究
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作者 董选普 蒋文明 +2 位作者 廖敦明 吴志超 罗云华 《大学教育》 2019年第11期8-10,共3页
基于当前高校工程教育专业认证的要求,论文首次提出了工科专业课堂“3D(Debate/Design/Doing)”教学法,其核心教学理念是“我思故我想,我想故我说,我说故我做,我做故我会”,即通过课堂辩论(Debate)、项目设计(Design)和项目实施(Do?ing)... 基于当前高校工程教育专业认证的要求,论文首次提出了工科专业课堂“3D(Debate/Design/Doing)”教学法,其核心教学理念是“我思故我想,我想故我说,我说故我做,我做故我会”,即通过课堂辩论(Debate)、项目设计(Design)和项目实施(Do?ing),将教师的课堂讲授信息通过这个过程进行批判性思辨,将理论知识和实际效果联系起来。该研究通过在材料加工工程专业模块课程铸造工艺和造型材料的教学实践,取得了所有选课学生的认同,真正做到了让学习过程由被动变为主动、由无趣变成有趣、由枯燥变为生动,学生由自卑变自信,使院系专业课程课堂教学和工程训练平台实现了无缝联合,对于提高工科专业的课堂教学效果具有广泛的借鉴意义,为达到国际工程专业认证标准提供了很好的教学示范作用。 展开更多
关键词 “3d(debate/design/doing)”教学法 课堂教学改革 工程专业认证
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Fast capture and stabilization of Li‐ions via physicochemical dual effects for an ultra‐stable self‐supporting Li metal anode
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作者 Xuzi Zhang Yue Li +1 位作者 Hao Zhang Ge Li 《Carbon Energy》 SCIE EI CAS CSCD 2023年第9期88-100,共13页
Lithium(Li)metal is regarded as one of the most promising anode candidates for next-generation batteries due to its extremely high specific capacity and low redox potential.However,its application is still hindered by... Lithium(Li)metal is regarded as one of the most promising anode candidates for next-generation batteries due to its extremely high specific capacity and low redox potential.However,its application is still hindered by the uncontrolled growth of dendritic Li and huge volume fluctuation during cycles.To address these issues,flexible and self-supporting three-dimensional(3D)interlaced Ndoped carbon nanofibers(NCNFs)coated with uniformly distributed 2D ultrathin NiCo_(2)S_(4)nanosheets(denoted CNCS)were designed to eliminate the intrinsic hotspots for Li deposition.Physicochemical dual effects of CNCS arise from limited surface Li diffusivity with a higher Li affinity,leading to uniform Li nucleation and less random accumulation of Li,as confirmed by ab initio molecular dynamics simulations.Due to the unique structure,exchange current density is reduced significantly and metallic Li is further contained within the interspace between the NCNF and NiCo_(2)S_(4)nanosheets,preventing the formation of dendritic Li.The symmetric cell with a Li/CNCS composite anode shows a long-running lifespan for almost 1200 h,with an exceptionally low and stable overpotential under 1mA cm^(-2)/1 mAh cm^(-2).A full cell coupled with a LiFePO4 cathode at a low N/P ratio of 2.45 shows typical voltage profiles but more significantly enhanced performance than that of a LiFePO4 cathode coupled with a bare Li anode. 展开更多
关键词 3d scaffold design Li affinity Li diffusivity Li metal anode long lifespan
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3D打印技术与计算机辅助设计应用在全膝关节置换治疗重度膝关节骨关节炎中的可行性 被引量:2
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作者 吴迪 司丽娜 +5 位作者 武丽珠 王建华 罗金伟 常乾坤 吕永明 杜元良 《中国组织工程研究》 CAS 北大核心 2023年第13期2051-2057,共7页
背景:3D打印技术、计算机辅助设计技术辅助全膝关节置换均有研究报道,两者联合辅助全膝关节置换治疗膝关节骨关节炎能否取得更好效果尚不得知。目的:探讨3D打印技术联合计算机辅助设计技术在全膝关节置换治疗重度膝关节骨关节炎中的应... 背景:3D打印技术、计算机辅助设计技术辅助全膝关节置换均有研究报道,两者联合辅助全膝关节置换治疗膝关节骨关节炎能否取得更好效果尚不得知。目的:探讨3D打印技术联合计算机辅助设计技术在全膝关节置换治疗重度膝关节骨关节炎中的应用价值。方法:前瞻性选择2018年10月至2020年10月承德医学院附属医院收治的93例重度膝关节骨关节炎患者,采用随机数字表法随机分为对照组(n=46)和观察组(n=47),分别行传统的人工全膝关节置换手术、3D打印+计算机辅助设计技术引导下的人工全膝关节置换手术。统计两组患者疼痛程度、应激相关指标、膝关节功能恢复及并发症发生情况。结果与结论:①观察组术后7,14 d的疼痛目测类比评分低于对照组(P<0.05),术后1 d的D-二聚体、纤维蛋白原降解产物水平低于对照组(P<0.05),血红蛋白水平高于对照组(P<0.05);②两组间术后6个月的美国特种外科医院膝关节评分比较差异无显著性意义(P>0.05),观察组术后6个月的膝关节活动范围大于对照组(P<0.05)、下肢力线角度小于对照组(P<0.05);③术后6个月,观察组出现内侧胫骨平台骨质缺失1例(并发症总发生率2%),对照组出现内侧胫骨平台骨质缺失1例、假体松动1例、切口感染2例(并发症总发生率9%),两组间并发症发生率比较差异无显著性意义(P>0.05);④结果表明,与传统全膝关节置换相比,3D打印联合CAD技术引导下的人工全膝关节置换治疗重度膝关节骨关节炎,可缓解疼痛、改善膝关节功能、减轻应激反应。 展开更多
关键词 膝关节骨关节炎 3d打印技术 计算机辅助设计 全膝关节置换 d-二聚体 纤维蛋白原降解产物 膝关节功能
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基于Design3D的汽轮机低压静叶三维气动优化设计 被引量:2
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作者 王喜华 范小平 +2 位作者 孙奇 钟刚云 贺伟 《东方汽轮机》 2012年第1期46-52,共7页
文章基于商业软件NuMECA的全三维优化设计平台Design3D,采用三维N-S方程流场计算、网格自动生成、三维叶片参数化造型与遗传算法寻优相结合的方法,在级环境下对600MW汽轮机静叶进行了三维叶片型线优化设计。优化目标是在流量基本不变的... 文章基于商业软件NuMECA的全三维优化设计平台Design3D,采用三维N-S方程流场计算、网格自动生成、三维叶片参数化造型与遗传算法寻优相结合的方法,在级环境下对600MW汽轮机静叶进行了三维叶片型线优化设计。优化目标是在流量基本不变的情况下尽可能地提高级轮周效率。优化设计后的叶片与原叶片相比,透平级的总-总效率提高了0.32%,级的轮周效率提高了0.39%。详细的流场分析表明,优化后叶片性能的提高主要是源于静叶总压损失的减小和透平级动静叶之间匹配的改善。 展开更多
关键词 空心静叶 design3d 遗传算法:三维气动优化
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Review on Applications of 3D Inverse Design Method for Pump 被引量:1
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作者 YIN Junlian WANG Dezhong 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2014年第3期520-527,共8页
The 3D inverse design method, which methodology is far superior to the conventional design method that based on geometrical description, is gradually applied in pump blade design. However, no complete description abou... The 3D inverse design method, which methodology is far superior to the conventional design method that based on geometrical description, is gradually applied in pump blade design. However, no complete description about the method is outlined. Also, there are no general rules available to set the two important input parameters, blade loading distribution and stacking condition. In this sense, the basic theory and the mechanism why the design method can suppress the formation of secondary flow are summarized. And also, several typical pump design cases with different specific speeds ranging from centrifugal pump to axial pump are surveyed. The results indicates that, for centrifugal pump and mixed pump or turbine, the ratio of blade loading on the hub to that on the shroud is more than unit in the fore part of the blade, whereas in the aft part, the ratio is decreased to satisfy the same wrap angle for hub and shroud. And the choice of blade loading type depends on the balancing of efficiency and cavitation. If the cavitation is more weighted, the better choice is aft-loaded, otherwise, the fore-loaded or mid-loaded is preferable to improve the efficiency. The stacking condition, which is an auxiliary to suppress the secondary flow, can have great effect on the jet-wake outflow and the operation range for pump. Ultimately, how to link the design method to modem optimization techniques is illustrated. With the know-how design methodology and the know-how systematic optimization approach, the application of optimization design is promising for engineering. This paper summarizes the 3D inverse design method systematically. 展开更多
关键词 PUMP 3d inverse design blade loading stacking condition optimization
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响应面法优化真菌CHS3发酵产物中柴胡皂苷d的提取工艺
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作者 刘博 高宁 《化学工程师》 CAS 2023年第12期90-95,100,共7页
目的确定从真菌CHS3发酵产物中提取柴胡皂苷d的最优工艺。方法以柴胡皂苷d产量为指标,利用单因素分析与响应面分析相结合,优化乙醇浓度、料液比、超声功率、超声时间和超声温度的实验条件。结果真菌CHS3发酵产物中提取柴胡皂苷d的最佳... 目的确定从真菌CHS3发酵产物中提取柴胡皂苷d的最优工艺。方法以柴胡皂苷d产量为指标,利用单因素分析与响应面分析相结合,优化乙醇浓度、料液比、超声功率、超声时间和超声温度的实验条件。结果真菌CHS3发酵产物中提取柴胡皂苷d的最佳提取条件为:72%的乙醇超声提取,料液比为1∶22(g∶m L),超声功率为300W,超声温度为56℃,超声时间为28min。该工艺条件下柴胡皂苷d的平均产量为3.928μg·g^(-1)。结论所得工艺条件稳定可靠,研究结果为利用发酵工程生产SSd提供理论与实验参考。 展开更多
关键词 内生真菌 柴胡皂苷d 响应面分析 BOX-BEHNKEN设计
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D-最优混料设计优化“贵州三宝酒”配方及品质分析 被引量:1
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作者 李雪 李立郎 +2 位作者 王瑜 杨娟 杨小生 《食品与发酵科技》 CAS 2023年第1期90-97,107,共9页
以贵州三宝(天麻、灵芝、杜仲)为配方原料,将其制作成一款富有酱香型风味又有健康属性的配制酒。采用D-最优混料实验设计,以γ-氨基丁酸(GABA)、总抗氧化能力(T-AOC)和感官评分为指标,考察天麻浸提液、灵芝浸提液和杜仲浸提液不同配比... 以贵州三宝(天麻、灵芝、杜仲)为配方原料,将其制作成一款富有酱香型风味又有健康属性的配制酒。采用D-最优混料实验设计,以γ-氨基丁酸(GABA)、总抗氧化能力(T-AOC)和感官评分为指标,考察天麻浸提液、灵芝浸提液和杜仲浸提液不同配比对其影响。获得贵州三宝酒的最佳配方为天麻浸提液49%、灵芝浸提液30%、杜仲浸提液21%,同时进行验证试验,优化后贵州三宝酒的GABA、T-AOC和感官评分分别为0.121 mg/mL、5.78μmol/mL、92.02分,与预测值相近。将优化得到的最佳配方进行香气成分和游离氨基酸的测定,结果表明:共检测出64种挥发性香气成分,其中酯类化合物是主要的香气成分;检测出21种游离氨基酸,包括7种人体必需氨基酸,总游离氨基酸含量为318.7 mg/L。 展开更多
关键词 d-最优混料设计 贵州三宝酒 挥发性成分 游离氨基酸
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基于Design3D的汽轮机低压静叶三维气动优化设计
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作者 王喜华 范小平 孙奇 《四川工程职业技术学院学报》 2012年第3期19-24,共6页
本文基于商业软件NUMECA的全三维优化设计平台Design3D,采用三维N-S方程流场计算、网格自动生成、三维叶片参数化造型与遗传算法寻优相结合的方法,在级环境下对600MW汽轮机静叶进行了三维叶片型线优化设计,优化目标是在流量基本不变... 本文基于商业软件NUMECA的全三维优化设计平台Design3D,采用三维N-S方程流场计算、网格自动生成、三维叶片参数化造型与遗传算法寻优相结合的方法,在级环境下对600MW汽轮机静叶进行了三维叶片型线优化设计,优化目标是在流量基本不变的情况下尽可能的提高级轮周效率。优化设计后的叶片与原叶片相比,透平级的总一总效率提高了0.32%,级的轮周效率提高了O.39%。详细的流场分析表明,优化后叶片性能的提高主要是源于静叶总压损失的减小和透平级动静叶之间匹配的改善。 展开更多
关键词 空心静叶 design3d 遗传算法 三维气动优化
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