由D-(-)-核糖合成Aigialomycin D C2′～C7′片段的简捷方法

Aigialomycin D(1) possesses a potent antitumor activity and anti-malarial activity. In this paper a concise route for the synthesis of the key C2′—C7′ fragment of aigialomycin D by using D-(-)-ribose was described. The fragment was synthesized in six steps in 37.2% overall yield, including protection of the vicinal diol, Wittig reaction of the lactol, hydrogenation, oxidative cleavage of the diol, terminal olefination and selective reduction of the ester. This work lays a good foundation for the total synthesis of aigialomycin D.

STUDY ON THE DECOLORIZATION OF D-RIBOSE ZYMOTIC FLUID BY RESIN ADSORPTION

In this paper, effects on of six type of resins the decolorization of D-ribosezymotic fluid have been studied for the fist time. The results show that resinNKA-II has the best effect. the decolorization rate of D-ribose zymotic fluid is91% at velocity of 1.0BV/hr and 25℃, the adsorption capacity can reach up to5.7BV. The effects of adsorption conditions as well as conditions of resinregeneration on the resin decolorization capability were also studied.

278.15-313.15K下糖-水二元体系的介电常数

测定了D-(-)-果糖、D-(+)-葡萄糖、D-(+)-半乳糖、D-(+)-木糖和D-(-)-核糖五种糖的水溶液在不同质量摩尔浓度和不同温度下的介电常数(D).结果表明,在一定温度下,这些糖的水溶液介电常数对数值都随糖浓度的增大而减小;在一定糖浓度时,介电常数值随温度升高而减小.果糖、葡萄糖、半乳糖和木糖水溶液的介电常数(D)随温度的变化均满足关系式:lgD=A1-B1(T-298.15),而核糖水溶液则符合:lgD=A2-B2(T-298.15)+C2(T-298.15)2.此外,这五种糖的水溶液的介电常数与摩尔分数(x)满足关系式:lg(D/D0)=-B3x.在相同温度和浓度时,介电常数的大小顺序通常为:水>半乳糖-水>果糖-水>葡萄糖-水≥木糖-水(而核糖较特殊).