D-900阴离子交换树脂纯化救必应中紫丁香苷工艺研究

目的研究D-900阴离子交换树脂对救必应中紫丁香苷的纯化工艺。方法采用高效液相色谱法和紫外分光光度法,以紫丁香苷保留率和溶液脱色率为指标,对树脂纯化条件进行考察。结果 D-900阴离子交换树脂纯化最佳工艺为树脂重量和样品体积比为1∶5,树脂柱径高比为1∶5,上柱流速为2 BV/h,在此条件下紫丁香苷保留率达80%以上,溶液脱色率达30%以上。结论紫丁香苷粗分离液通过树脂纯化的工艺,简单易行。

THE SEPARATION,PURIFICATION AND DECOLORIZATION OF NEW ANTIBIOTICS-MILUPEINAN USING ADSORPTION RESIN

Adsorption resin AAS was used for the separation and purification of milupeinan (M-13) from its mother liquor. The good adsorption property of AAS adsorption resin was found for milupeinan (M-13) compared with the Diaion CHP 20p. When acetone and water (2:1 in volume) were used as desorption reagents, it was found that 3 times of bed volume of the desorption reagents would make the AAS resin which was saturately adsorpted M-13 desorption completely. Also a macroporous anion exchange resin (Poly-4-vinylpyridine type) D-280 was used for the decolourization from M-13 solution. Good results was given when the sv=1~2.

两级树脂吸附处理DSD酸生产废水研究

研究了ND-900树脂对DSD酸废水的吸附效果。结果表明,温度污染物在ND-900树脂中的吸附行为影响较大,低温更适合ND-900树脂的吸附。在吸附初期,流量越小,吸附效果越好;在吸附后期,随着低流量的树脂吸附接近饱和,出水效果明显降低。二级吸附效果更好。在流量为1BV/h时,选用1 BV 8%Na OH+3 BV H2O组合作为脱附剂,脱附率可达98%左右,经多批次实验,效果稳定。