Despite the continuous improvement of the widely used empirical model international reference ionosphere(IRI),the recently appeared new models must be tested worldwide.Testing along the meridians has the advantage of ...Despite the continuous improvement of the widely used empirical model international reference ionosphere(IRI),the recently appeared new models must be tested worldwide.Testing along the meridians has the advantage of dealing with the latitudinal dependent parameters.This paper uses new models of parameters foF2(critical frequency),TEC(total electron content),andτ(equivalent slab thickness of the ionosphere),which are of great importance for evaluating the effects of space weather.IRI-Plas,NNT2F2,and NTSM models were tested using data from 6 ionosondes located along the meridian 110°E in March 2012.It is shown that the IRI-Plas model provides the closest values to experiment with respect toτ,while the NTSM model provides a rather limited reflection of the latitude dependence.Analyses of foF2(NNT2F2)have shown that,the NNT2F2 model provides good conformity with experimental values in this area,but it is very dependent on the TEC processing method.The latitudinal dependences of foF2 obtained with TEC and polynomial dependenceτ(Appr)showed the presence of positive deviations from medians not only during disturbances but also quiet periods,longitudinally at the meridian.展开更多
Summary: In order to investigate whether Arg110Gln polymorphism in the coding region of the IL-13 gene is associated with asthma and total plasma IgE level in Han nationality in Hubei Chinese population, the allele fr...Summary: In order to investigate whether Arg110Gln polymorphism in the coding region of the IL-13 gene is associated with asthma and total plasma IgE level in Han nationality in Hubei Chinese population, the allele frequency of 4257(g/a) site and Arg110Gln genotype of IL-13 was detected by using restriction fragment length polymorphism in Han nationality in Hubei Chinese population including 43 asthmatic children, 45 asthmatic adults, 31 control children and 46 control adults. Total plasma IgE was measured by Chemiluminescence assay. The results showed that the frequency of allele A at 4257 bp of IL-13 in children and adults was 0.39 and 0.32, respectively. The GlnGln form of Arg110Gln polymorphism of IL-13 gene was associated with susceptibility of asthma and elevated total plasma IgE in children (P =0.030 and 0.0009, respectively), but not with them in adults (P=0.219 and 0.174, respectively). Our results suggest that the Arg110Gln polymorphism of IL-13 gene is associated with susceptibility of asthma and elevated total plasma IgE in Chinese children of Han nationality in Hubei, but not with them in adults.展开更多
基金financially supported by Southern Federal University,Russia,2020 Project Vn Gr/2020-03-IF
文摘Despite the continuous improvement of the widely used empirical model international reference ionosphere(IRI),the recently appeared new models must be tested worldwide.Testing along the meridians has the advantage of dealing with the latitudinal dependent parameters.This paper uses new models of parameters foF2(critical frequency),TEC(total electron content),andτ(equivalent slab thickness of the ionosphere),which are of great importance for evaluating the effects of space weather.IRI-Plas,NNT2F2,and NTSM models were tested using data from 6 ionosondes located along the meridian 110°E in March 2012.It is shown that the IRI-Plas model provides the closest values to experiment with respect toτ,while the NTSM model provides a rather limited reflection of the latitude dependence.Analyses of foF2(NNT2F2)have shown that,the NNT2F2 model provides good conformity with experimental values in this area,but it is very dependent on the TEC processing method.The latitudinal dependences of foF2 obtained with TEC and polynomial dependenceτ(Appr)showed the presence of positive deviations from medians not only during disturbances but also quiet periods,longitudinally at the meridian.
文摘Summary: In order to investigate whether Arg110Gln polymorphism in the coding region of the IL-13 gene is associated with asthma and total plasma IgE level in Han nationality in Hubei Chinese population, the allele frequency of 4257(g/a) site and Arg110Gln genotype of IL-13 was detected by using restriction fragment length polymorphism in Han nationality in Hubei Chinese population including 43 asthmatic children, 45 asthmatic adults, 31 control children and 46 control adults. Total plasma IgE was measured by Chemiluminescence assay. The results showed that the frequency of allele A at 4257 bp of IL-13 in children and adults was 0.39 and 0.32, respectively. The GlnGln form of Arg110Gln polymorphism of IL-13 gene was associated with susceptibility of asthma and elevated total plasma IgE in children (P =0.030 and 0.0009, respectively), but not with them in adults (P=0.219 and 0.174, respectively). Our results suggest that the Arg110Gln polymorphism of IL-13 gene is associated with susceptibility of asthma and elevated total plasma IgE in Chinese children of Han nationality in Hubei, but not with them in adults.
