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Ultraviolet photodetectors based on ferroelectric depolarization field
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作者 Xiaoyu Zhou Qingqing Ke +2 位作者 Silin Tang Jilong Luo Zihan Lu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2023年第2期487-498,I0013,共13页
Ultraviolet(UV)photodetectors are extensively adopted in the fields of the Internet of Things,optical communications and imaging.Nowadays,with broadening the application scope of UV photodetectors,developing integrate... Ultraviolet(UV)photodetectors are extensively adopted in the fields of the Internet of Things,optical communications and imaging.Nowadays,with broadening the application scope of UV photodetectors,developing integrated devices with more functionalities rather than basic photo-detecting ability are highly required and have been triggered ever-growing interest in scientific and industrial communities.Ferroelectric thin films have become a potential candidate in the field of UV detection due to their wide bandgap and unique photovoltaic characteristics.Additionally,ferroelectric thin films perform excellent dielectric,piezoelectric,pyroelectric,acousto-optic effects,etc.,which can satisfy the demand for the diversified development of UV detectors.In this review,according to the different roles of ferroelectric thin films in the device,the UV photodetectors based on ferroelectric films are classified into ferroelectric depolarization field driven type,ferroelectric depolarization field and built-in electric field co-driven type,and ferroelectric field enhanced type.These three types of ferroelectric UV photodetectors have great potential and are expected to promote the development of a new generation of UV detection technology.At the end of the paper,the advantages and challenges of three types of ferroelectric UV photodetectors are summarized,and the possible development direction in the future is proposed. 展开更多
关键词 UV photodetector FERROELECTRIC Thin film depolarization field Built-in electric field
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Selective extraction of titanium from Ti-bearing slag via the enhanced depolarization effect of liquid copper cathode 被引量:7
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作者 Zhenghao Pu Handong Jiao +2 位作者 Zhishan Mi Mingyong Wang Shuqiang Jiao 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2020年第3期43-48,共6页
Ti-bearing slag(TiO2>20 wt%)is a valuable titanium secondary resource.The extraction of titanium from the slag is difficult due to the complex composition and structure.Although molten oxide electrolysis is conside... Ti-bearing slag(TiO2>20 wt%)is a valuable titanium secondary resource.The extraction of titanium from the slag is difficult due to the complex composition and structure.Although molten oxide electrolysis is considered as a promising method,silicon will be preferentially electroreduced compared to titanium due to low theoretical decomposition voltage.In this work,a liquid copper cathode is used to selectively extract titanium from molten Al2O3-MgO-CaO-TiO2-SiO2 electrolyte.It is found that comparing to silicon,titanium can be preferentially reduced by one-step electron transfer due to the enhanced depolarization effect on a liquid copper cathode.So,Ti-Cu alloys are firstly obtained from molten Ti-bearing slag,and then Ti-Si alloys are co-electrodeposited in the molten oxide electrolyte with low TiO2 content.It may be ascribed to the larger binding force between titanium and copper than that between silicon and copper.It provides an effective strategy for the separation of titanium from of Ti-bearing slag. 展开更多
关键词 TITANIUM alloys MOLTEN OXIDES ELECTROLYSIS Liquid CATHODE Selective depolarization
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Orientation-dependent depolarization of supercontinuum in BaF2 crystal 被引量:1
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作者 李子熙 龚成 +3 位作者 邵天骄 华林强 卞学滨 柳晓军 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第1期324-328,共5页
We present a systematic investigation of the depolarization properties of a supercontinuum accompanied with femtosecond laser filamentation in barium fluoride(BaF2)crystal.It is found that the depolarization of the su... We present a systematic investigation of the depolarization properties of a supercontinuum accompanied with femtosecond laser filamentation in barium fluoride(BaF2)crystal.It is found that the depolarization of the supercontinuum depends strongly on the crystal orientations with respect to the incident laser polarization.At most crystal orientations,the depolarization of the supercontinuum rises with the increase of the input laser energies and finally saturates.While at 45°,the depolarization of the supercontinuum is not changed and keeps nearly negligible with the increase of the input laser energies.These peculiar depolarization properties of the supercontinuum can be ascribed to the orientation dependence of the cross-polarized wave(XPW)generation and ionization-induced plasma scattering in the BaF2 crystal. 展开更多
关键词 femtosecond laser filamentation SUPERCONTINUUM depolarization
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Depolarization Effects of Incoherently Scattered Electromagnetic Waves by Inhomogeneous Magnetized Plasma Slab 被引量:1
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作者 George Jandieri Akira I shimaru Vakhtang Jandieri 《Journal of Electromagnetic Analysis and Applications》 2011年第11期471-478,共8页
Scattering of the electromagnetic waves by a randomly inhomogeneous electrically gyrotropic slab are studied using the perturbation method. Second order statistical moments of the ordinary and extraordinary waves scat... Scattering of the electromagnetic waves by a randomly inhomogeneous electrically gyrotropic slab are studied using the perturbation method. Second order statistical moments of the ordinary and extraordinary waves scattered by the magnetized plasma slab are obtained using the boundary conditions for an arbitrary correlation function of electron density fluctuations. Normalized correlation functions at quasi-longitudinal propagation along the external magnetic field are calculated for the carrier frequency 0.1 MHz and 40 MHz. Isolines of the normalized variance of Faraday angle are constructed for the anisotropic Gaussian correlation function at various anisotropy factors of irregularities. Obtained results are in a good agreement with the experimental data. 展开更多
关键词 Statistical MOMENTS Fluctuations IRREGULARITIES MAGNETIZED Plasma depolarization Scattering
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Depolarization field in relaxor-based ferroelectric single crystals under one-cycle bipolar pulse drive
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作者 陈传文 项阳 +4 位作者 汤立国 崔莲 林宝卿 杜伟东 曹文武 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第12期326-330,共5页
The [001]c-polarized(1-x)Pb(Mg1/3Nb2/3)O3–xPbTiO3(PMN-PT) single crystals are widely used in ultrasonic detection transducers and underwater acoustic sensors. However, the relatively small coercive field( 2 kV/cm) of... The [001]c-polarized(1-x)Pb(Mg1/3Nb2/3)O3–xPbTiO3(PMN-PT) single crystals are widely used in ultrasonic detection transducers and underwater acoustic sensors. However, the relatively small coercive field( 2 kV/cm) of such crystals restricts their application at high frequencies because the driving field will exceed the coercive field. The depolarization field can be considerably larger in an antiparallel direction than in a parallel direction with respect to polarization when the bipolar driving cycle starts. Thus, if the direction of the sine wave signal in the first half cycle is opposite to the polarization direction, then the depolarized domains can be repolarized in the second half of the sine cycle. However, if the direction of the sine wave signal in the first half of the cycle is along the polarization direction, then the change is negligible,and the domains switched in the second half of the sine cycle cannot be recovered. The design of electric driving method needs to allow the use of a large applied field to emit strong enough signals and produce good images. This phenomenon combined with the coercive field increases with the driving frequency, thereby making the PMN-PT single crystals usable for high-frequency applications. As such, the applied field can be considerably larger than the conventionally defined coercive field. 展开更多
关键词 piezoelectric crystal coercive field depolarization field bipolar pulse
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Numerical simulation study on spin resonant depolarization due to spin-orbit coupling
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作者 蓝杰钦 徐宏亮 《Chinese Physics B》 SCIE EI CAS CSCD 2012年第8期295-301,共7页
The spin polarization phenomenon in lepton circular accelerators had been known for many years. It provides a new approach for physicists to study the spin feature of fundamental particles and the dynamics of spin-orb... The spin polarization phenomenon in lepton circular accelerators had been known for many years. It provides a new approach for physicists to study the spin feature of fundamental particles and the dynamics of spin-orbit coupling, such as spin resonances. We use numerical simulation to study the features of spin under the modulation of orbital motion in an electron storage ring. The various cases of depolarization due to spin-orbit coupling through an emitting photon and misalignment of magnets in the ring are discussed. 展开更多
关键词 spin polarization and resonant depolarization spin orbit coupling spin flip numericalsimulation
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mTORC1 induces plasma membrane depolarization and promotes preosteoblast senescence by regulating the sodium channel Scn1a
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作者 Ajuan Chen Jian Jin +12 位作者 Shasha Cheng Zezheng Liu Cheng Yang Qingjing Chen Wenquan Liang Kai Li Dawei Kang Zhicong Ouyang Chenfeng Yao Xiaochun Bai Qingchu Li Dadi Jin Bin Huang 《Bone Research》 SCIE CAS CSCD 2022年第2期394-408,共15页
Senescence impairs preosteoblast expansion and differentiation into functional osteoblasts,blunts their responses to bone formation-stimulating factors and stimulates their secretion of osteoclast-activating factors.D... Senescence impairs preosteoblast expansion and differentiation into functional osteoblasts,blunts their responses to bone formation-stimulating factors and stimulates their secretion of osteoclast-activating factors.Due to these adverse effects,preosteoblast senescence is a crucial target for the treatment of age-related bone loss;however,the underlying mechanism remains unclear.We found that mTORC1 accelerated preosteoblast senescence in vitro and in a mouse model.Mechanistically,mTORC1 induced a change in the membrane potential from polarization to depolarization,thus promoting cell senescence by increasing Ca^(2+)influx and activating downstream NFAT/ATF3/p53 signaling.We further identified the sodium channel Scn1a as a mediator of membrane depolarization in senescent preosteoblasts.Scn1a expression was found to be positively regulated by mTORC1 upstream of C/EBPα,whereas its permeability to Na^(+)was found to be gated by protein kinase A(PKA)-induced phosphorylation.Prosenescent stresses increased the permeability of Scn1a to Na^(+)by suppressing PKA activity and induced depolarization in preosteoblasts.Together,our findings identify a novel pathway involving mTORC1,Scn1a expression and gating,plasma membrane depolarization,increased Ca^(2+)influx and NFAT/ATF3/p53 signaling in the regulation of preosteoblast senescence.Pharmaceutical studies of the related pathways and agents might lead to novel potential treatments for agerelated bone loss. 展开更多
关键词 depolarization mTORC1 treatment
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Spin depolarization dynamics of WSe2 bilayer
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作者 牛秉慧 叶加良 +2 位作者 李婷 李莹 张新惠 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第5期447-452,共6页
In this work, the spin dynamics of a centrosymmetric WSe2 bilayer has been investigated by the two-color timeresolved Kerr rotation together with helicity-resolved transient reflectance techniques. Two depolarization ... In this work, the spin dynamics of a centrosymmetric WSe2 bilayer has been investigated by the two-color timeresolved Kerr rotation together with helicity-resolved transient reflectance techniques. Two depolarization processes associated with the direct transition are discovered at a low temperature of 10 K, with the characteristic decaying time of~3.8 ps and ~20 ps, respectively. The short decay time of ~3.8 ps is suggested to be the exciton spin lifetime of the WSe2 bilayer, which is limited by the short exciton lifetime of the WSe2 bilayer and the rapid intervalley electron–hole exchange interaction between K^+ and K^- valley in the same layer as that of monolayer. The long decay time of ~20 ps is suggested to be the spin lifetime of photo-excited electrons, whose spin relaxation is governed by the rapid intervalley scattering from the K valley to the global minimum Σ valley and the subsequent interlayer charge transfer in WSe2 bilayer.Our experimental results prove the existence of the spin-polarized excitons and carriers even in centrosymmetric transition metal dichalcogenides(TMDCs) bilayers, suggesting their potential valleytronic and spintronic device applications. 展开更多
关键词 spin depolarization dynamics WSe2 bilayer time-resolved Kerr rotation
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Impact of Depolarization Phenomena on Polarized MIMO Channel Performances
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作者 Nuttapol PRAYONGPUN Kosai RAOOF 《International Journal of Communications, Network and System Sciences》 2008年第2期124-129,共6页
The performance and capacity of multiple-input multiple-output (MIMO) wireless channels are limited by the spatial fading correlation between antenna elements. This limitation is due to the use of mono polarized anten... The performance and capacity of multiple-input multiple-output (MIMO) wireless channels are limited by the spatial fading correlation between antenna elements. This limitation is due to the use of mono polarized antennas at receiver and transmitter sides. In this paper, in order to reduce the antenna correlation, the polarization diversity technique is employed. Although the spatial antenna correlation is attenuated for multi-polarization configurations, the cross-polar components appear. This paper highlights the impact of depolarization effect on the MIMO channel capacity for a 4&amp;amp;amp;#215;4 uniform linear antenna array. We assume that the channel is unknown at the transmitter and perfectly known at the receiver so that equal power is distributed to each of the transmit antennas. The numerical results illustrate that for low depolarization and spatial correlation, the capacity of single-polarization configuration behaves better than that of multi-polarization configuration. 展开更多
关键词 MULTIPLE-INPUT Multiple-output (MIMO) Channel Capacity Spatial FADING Correlation Multi-polarized Antenna Arrays depolarization Effects.
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Photo-Induced Thermally Stimulated Depolarization Current (TSDC) in Natural and Synthetic Alexandrite (BeAl2O4:Cr3+)
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作者 Neilo Marcos Trindade Ana Regina Blak +2 位作者 Elisabeth Mateus Yoshimura Luis Vicente de Andrade Scalvi Rosa Maria Fernandes Scalvi 《Materials Sciences and Applications》 2016年第12期881-894,共14页
The investigation of electrical properties in alexandrite (BeAl<sub>2</sub>O<sub>4</sub>:Cr<sup>3+</sup>) in synthetic and natural forms is presented in this paper. Alexandrite is a... The investigation of electrical properties in alexandrite (BeAl<sub>2</sub>O<sub>4</sub>:Cr<sup>3+</sup>) in synthetic and natural forms is presented in this paper. Alexandrite is a rare and precious mineral that changes color according to the light incident on it. In the synthetic form, it is used technologically as an active laser medium. The electrical characterization was obtained using the Thermally Stimulated Depolarization Current (TSDC) technique, an interesting tool to study the behavior of impurities in insulators. Alexandrite presented the electric dipole relaxation phenomenon, both in natural and in synthetic samples. It was possible to observe TSDC bands for the synthetic sample at around 170 K, and at around 175 K for the natural sample. Besides, photo-induced TSDC measurements were performed through the excitement of the samples by using a continuous wave argon laser. In addition, photoluminescence measurements were performed to verify in advance whether the laser light would be absorbed by the sample, and in order to complement the photo-induced TSDC measurements analysis. The results of photo-induced TSDC experiments have contributed to the understanding of the TSDC bands behavior: the results obtained with the technique suggest that there is an effective participation of Cr<sup>3+</sup> ions in the formation of TSDC bands because they were more intense when the sample was exposed to the argon laser beam. 展开更多
关键词 ALEXANDRITE Chrysoberyl Thermally Stimulated depolarization Current (TSDC) PHOTOLUMINESCENCE Photo-Induced
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Depolarization mitigated in ferroelectric Hf_(0.5)Zr_(0.5)O_(2)ultrathin films(<5 nm)on Si substrate by interface engineering
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作者 Se Hyun Kim Younghwan Lee +6 位作者 Dong Hyun Lee Geun Hyeong Park Hyun Woo Jeong Kun Yang Yong Hyeon Cho Young Yong Kim Min Hyuk Park 《Journal of Advanced Ceramics》 SCIE EI CAS CSCD 2024年第3期282-292,共11页
(Hf,Zr)O_(2)offers considerable potential for next-generation semiconductor devices owing to its nonvolatile spontaneous polarization at the nanoscale.However,scaling this material to sub-5 nm thickness poses several ... (Hf,Zr)O_(2)offers considerable potential for next-generation semiconductor devices owing to its nonvolatile spontaneous polarization at the nanoscale.However,scaling this material to sub-5 nm thickness poses several challenges,including the formation of an interfacial layer and high trap concentration.In particular,a low-k SiO_(2)interfacial layer is naturally formed when(Hf,Zr)O_(2)films are directly grown on a Si substrate,leading to high depolarization fields and rapid reduction of the remanent polarization.To address these issues,we conducted a study to significantly improve ferroelectricity and switching endurance of(Hf,Zr)O_(2)films with sub-5 nm thicknesses by inserting a TiO_(2)interfacial layer.The deposition of a Ti film prior to Hf_(0.5)Zr_(0.5)O_(2)film deposition resulted in a high-k TiO_(2)interfacial layer and prevented the direct contact of Hf_(0.5)Zr_(0.5)O_(2)with Si.Our findings show that the high-k TiO_(2)interfacial layer can reduce the SiO_(2)/Si interface trap density and the depolarization field,resulting in a switchable polarization of 60.2μC/cm^(2)for a 5 nm thick Hf_(0.5)Zr_(0.5)O_(2)film.Therefore,we propose that inserting a high-k TiO_(2)interfacial layer between the Hf_(0.5)Zr_(0.5)O_(2)film and the Si substrate may offer a promising solution to enhancing the ferroelectricity and reliability of(Hf,Zr)O_(2)grown on the Si substrate and can pave the way for next-generation semiconductor devices with improved performance. 展开更多
关键词 FERROELECTRIC charge trapping HAFNIA depolarization
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La_(2)O_(3)-modified BiYbO_(3)–Pb(Zr,Ti)O_(3) ternary piezoelectric ceramics with enhanced electrical properties and thermal depolarization temperature 被引量:1
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作者 Yu Chen Lingfeng Li +3 位作者 Zhi Zhou Yiying Wang Qiang Chen Qingyuan Wang 《Journal of Advanced Ceramics》 SCIE EI CAS CSCD 2023年第8期1593-1611,共19页
High-performance Pb(Zr_(1−x)Ti_(x))O_(3)(PZT)piezoceramics are urgently desired by the market in view of their expanded operating temperature range,reduced property temperature dependence,and enhanced sensitivity and ... High-performance Pb(Zr_(1−x)Ti_(x))O_(3)(PZT)piezoceramics are urgently desired by the market in view of their expanded operating temperature range,reduced property temperature dependence,and enhanced sensitivity and acoustic power.In this work,we reported a kind of low-cost and high-performance 0.06BiYbO_(3)–0.94Pb(Zr_(0.48)Ti_(0.52))O_(3) ternary piezoceramics;the modifying effects of La_(2)O_(3) on this perovskite system were investigated in terms of the structures,electrical properties,and thermal depolarization behaviors of ceramics.The field-dependent dielectric and conduction properties indicated that there are close correlations among oxygen vacancies(VO),conducting electrons,and intrinsic conduction process.The degradation in ferroelectric properties observed in those samples doped with more than 0.15 wt%of La_(2)O_(3) indicated that the occupying mechanisms of La^(3+)changed from the donor substitution for Pb^(2+)to the isovalent substitution for Bi^(3+).The thermally depoling micromechanisms of ceramics were revealed from the thermodynamic processes of defect dipoles and intrinsic dipoles within ferroelectric domains.The sample doped with 0.15 wt%of La_(2)O_(3) shows excellent electrical properties with TC=387℃,d33=332 pC/N,TKε=5.81×10^(−3)℃−1,Pr=20.66μC/cm^(2),Td=356℃.The significantly enhanced electrical properties and thermal depolarization temperature benefited from the donor substitution of La3+,decreasing the oxygen vacancy concentration in the lattice and possibly optimizing the ferroelectric domain structure of ceramics. 展开更多
关键词 BiYbO_(3)-Pb(Zr_(1−x)Ti_(x))O_(3)(BY-PZT)piezoceramics La_(2)O_(3) ferroelectric domain switching(Sswitch) defect dipoles thermal depolarization behaviors
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Depolarization of intense laser beams by dynamic plasma density gratings
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作者 Y.X.Wang S.M.Weng +9 位作者 P.Li Z.C.Shen X.Y.Jiang J.Huang X.L.Zhu H.H.Ma X.B.Zhang X.F.Li Z.M.Sheng J.Zhang 《High Power Laser Science and Engineering》 SCIE EI CAS CSCD 2023年第3期48-56,共9页
As a typical plasma-based optical element that can sustain ultra-high light intensity,plasma density gratings driven by intense laser pulses have been extensively studied for wide applications.Here,we show that the pl... As a typical plasma-based optical element that can sustain ultra-high light intensity,plasma density gratings driven by intense laser pulses have been extensively studied for wide applications.Here,we show that the plasma density grating driven by two intersecting driver laser pulses is not only nonuniform in space but also varies over time.Consequently,the probe laser pulse that passes through such a dynamic plasma density grating will be depolarized,that is,its polarization becomes spatially and temporally variable.More importantly,the laser depolarization may spontaneously take place for crossed laser beams if their polarization angles are arranged properly.The laser depolarization by a dynamic plasma density grating may find application in mitigating parametric instabilities in laser-driven inertial confinement fusion. 展开更多
关键词 depolarization high-power laser plasma density grating
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On the functions of astrocyte-mediated neuronal slow inward currents
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作者 Balázs Pál 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第12期2602-2612,共11页
Slow inward currents are known as neuronal excitatory currents mediated by glutamate release and activation of neuronal extra synaptic N-met hyl-D-aspartate receptors with the contribution of astrocytes.These events a... Slow inward currents are known as neuronal excitatory currents mediated by glutamate release and activation of neuronal extra synaptic N-met hyl-D-aspartate receptors with the contribution of astrocytes.These events are significantly slower than the excitatory postsynaptic currents.Parameters of slow inward currents are determined by seve ral factors including the mechanisms of astrocytic activation and glutamate release,as well as the diffusion pathways from the release site towards the extra synaptic recepto rs.Astrocytes are stimulated by neuronal network activity,which in turn excite neurons,forming an astrocyte-neuron feedback loop.Mostly as a consequence of brain edema,astrocytic swelling can also induce slow inward currents under pathological conditions.There is a growing body of evidence on the roles of slow inward currents on a single neuron or local network level.These events often occur in synchro ny on neurons located in the same astrocytic domain.Besides synchronization of neuronal excitability,slow inward currents also set synaptic strength via eliciting timing-dependent synaptic plasticity.In addition,slow inward currents are also subject to non-synaptic plasticity triggered by long-la sting stimulation of the excitatory inputs.Of note,there might be important regionspecific differences in the roles and actions triggering slow inward currents.In greater networks,the pathophysiological roles of slow inward currents can be better understood than physiological ones.Slow inward currents are identified in the pathophysiological background of autism,as slow inward currents drive early hypersynchrony of the neural networks.Slow inward currents are significant contributors to paroxysmal depolarizational shifts/interictal spikes.These events are related to epilepsy,but also found in Alzheimer's disease,Parkinson's disease,and stroke,leading to the decline of cognitive functions.Events with features overlapping with slow inward currents(excitatory,N-methyl-Daspartate-receptor mediated currents with astrocytic contribution) as ischemic currents and spreading depolarization also have a well-known pathophysiological role in worsening consequences of stroke,traumatic brain injury,or epilepsy.One might assume that slow inward currents occurring with low frequency under physiological conditions might contribute to synaptic plasticity and memory formation.However,to state this,more experimental evidence from greater neuronal networks or the level of the individual is needed.In this review,I aimed to summarize findings on slow inward currents and to speculate on the potential functions of it. 展开更多
关键词 ASTROCYTE cortical spreading depolarization gliotransmission GLUTAMATE neural synchronization NMDA receptor paroxysmal depolarizational shift slow inward current
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Gabapentinoids for the treatment of stroke
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作者 Ying Zhang Chenyu Zhang +3 位作者 Xiaoli Yi Qi Wang Tiejun Zhang Yuwen Li 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第7期1509-1516,共8页
Gabapentinoid drugs(pregabalin and gabapentin) have been successfully used in the treatment of neuro pathic pain and in focal seizure prevention.Recent research has demonstrated their potent activities in modulating n... Gabapentinoid drugs(pregabalin and gabapentin) have been successfully used in the treatment of neuro pathic pain and in focal seizure prevention.Recent research has demonstrated their potent activities in modulating neurotransmitter release in neuronal tissue,oxidative stress,and inflammation,which matches the mechanism of action via voltage-gated calcium channels.In this review,we briefly elaborate on the medicinal history and ligand-binding sites of gabapentinoids.We systematically summarize the preclinical and clinical research on gabapentinoids in stroke,including ischemic stro ke,intracerebral hemorrhage,subarachnoid hemorrhage,seizures after stro ke,cortical spreading depolarization after stroke,pain after stroke,and nerve regeneration after stro ke.This review also discusses the potential to rgets of gabapentinoids in stroke;however,the existing results are still unce rtain regarding the effect of gabapentinoids on stroke and related diseases.Further preclinical and clinical trials are needed to test the therapeutic potential of gabapentinoids in stroke.Therefore,gabapentinoids have both opportunities and challenges in the treatment of stroke. 展开更多
关键词 cortical spreading depolarization gabapentinoid intracerebral hemorrhage pain after stroke STROKE subarachnoid hemorrhage
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Adenosine A_(2A)receptor blockade attenuates excitotoxicity in rat striatal medium spiny neurons during an ischemic-like insult
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作者 Elisabetta Coppi Federica Cherchi Alasdair J.Gibb 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第2期255-257,共3页
During brain ischemia,excitotoxicity and peri-infarct depolarization injuries occur and cause cerebral tissue damage.Indeed,anoxic depolarization,consisting of massive neuronal depolarization due to the loss of membra... During brain ischemia,excitotoxicity and peri-infarct depolarization injuries occur and cause cerebral tissue damage.Indeed,anoxic depolarization,consisting of massive neuronal depolarization due to the loss of membrane ion gradients,occurs in vivo or in vitro during an energy failure.The neuromodulator adenosine is released in huge amounts during cerebral ischemia and exerts its effects by activating specific metabotropic receptors,namely:A_(1),A_(2A),A_(2B),and A_(3).The A_(2A)receptor subtype is highly expressed in striatal medium spiny neurons,which are particularly susceptible to ischemic damage.Evidence indicates that the A2Areceptors are upregulated in the rat striatum after stroke and the selective antagonist SCH58261 protects from exaggerated glutamate release within the first 4 hours from the insult and alleviates neurological impairment and histological injury in the following 24 hours.We recently added new knowledge to the mechanisms by which the adenosine A2Areceptor subtype participates in ischemia-induced neuronal death by performing patch-clamp recordings from medium spiny neurons in rat striatal brain slices exposed to oxygen and glucose deprivation.We demonstrated that the selective block of A2Areceptors by SCH58261 significantly reduced ionic imbalance and delayed the anoxic depolarization in medium spiny neurons during oxygen and glucose deprivation and that the mechanism involves voltage-gated K+channel modulation and a presynaptic inhibition of glutamate release by the A2Areceptor antagonist.The present review summarizes the latest findings in the literature about the possibility of developing selective ligands of A2Areceptors as advantageous therapeutic tools that may contribute to counteracting neurodegeneration after brain ischemia. 展开更多
关键词 adenosine A_(2A)receptors anoxic depolarization brain ischemia glutamate excitotoxicity medium spiny neurons oxygen and glucose deprivation
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Depolarization index from Mueller matrix descatters imaging in turbid water 被引量:7
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作者 刘飞 张仕超 +4 位作者 韩平丽 陈方熠 赵琳 范颖颖 邵晓鹏 《Chinese Optics Letters》 SCIE EI CAS CSCD 2022年第2期160-165,共6页
Polarization underwater imaging is of great potential to target detection in turbid water. Typical methods are challenged by the requirement on degrees of polarization(Do Ps) of both target light and backscattering. A... Polarization underwater imaging is of great potential to target detection in turbid water. Typical methods are challenged by the requirement on degrees of polarization(Do Ps) of both target light and backscattering. A polarization descattering imaging method was developed using the Mueller matrix, which in turn derived a depolarization(Dep) index from the Mueller matrix to characterize scattering media by estimating the transmittance map by combining a developed optimal function.By quantifying light attenuation with the transmittance map, a clear vision of targets can be recovered. Only using the information of scattering media, the underwater vision under diverse water turbidity was enhanced by the results of experimental data. 展开更多
关键词 Mueller matrix SCATTERING depolarization underwater imaging
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Seasonal variability of cirrus depolarization properties derived from CALIPSO lidar measurements over Beijing in China 被引量:4
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作者 路小梅 江月松 +2 位作者 张绪国 周波 欧军 《Chinese Optics Letters》 SCIE EI CAS CSCD 2010年第2期127-129,共3页
The seasonal variability of cirrus depolarization ratio and its altitude at the region of Beijing (39.93°N, 116.43°E, the capital of China) are presented. From the results obtained from the cloud aerosol l... The seasonal variability of cirrus depolarization ratio and its altitude at the region of Beijing (39.93°N, 116.43°E, the capital of China) are presented. From the results obtained from the cloud aerosol lidar and infrared pathfinder satellite observations lidar measurements, it appears that the values of depolarization ratio and altitude of cirrus are generally higher in autumn and summer than those in spring and winter, and the cirrus altitude is modulated by the height of tropopause. Additionally, the depolarization ratio tends to linearly vary with the increase of altitude and the decrease of temperature. 展开更多
关键词 CALIPSO Seasonal variability of cirrus depolarization properties derived from CALIPSO lidar measurements over Beijing in China OVER
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Influence of thermal reduced depolarization on a repetition-frequency laser amplifier and compensation 被引量:1
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作者 Xin-ying Jiang Xiong-wei Yan +3 位作者 Zhen-guo Wang Jian-gang Zheng Ming-zhong Li Jing-qin Su 《High Power Laser Science and Engineering》 SCIE CAS CSCD 2015年第1期76-80,共5页
Thermal stress can induce birefringence in a laser medium, which can cause depolarization of the laser. The depolarization effect will be very severe in a high-average-power laser. Because the depolarization will make... Thermal stress can induce birefringence in a laser medium, which can cause depolarization of the laser. The depolarization effect will be very severe in a high-average-power laser. Because the depolarization will make the frequency doubling efficiency decline, it should be compensated. In this paper, the thermal characteristics of two kinds of materials are analyzed in respect of temperature, thermal deformation and thermal stress. The depolarization result from thermal stress was simulated. Depolarization on non-uniform pumping was also simulated, and the compensation method is discussed. 展开更多
关键词 depolarization depolarization COMPENSATION THERMAL BIREFRINGENCE
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Depolarization-induced PKC activities suppress myogenin-driven AChR γ gene promoter activity
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作者 DANG Xitong and JIA HongtiDepartment of Biochemistry and Molecular Biology, Beijing Medical University, Beijing 100083, China 《Chinese Science Bulletin》 SCIE EI CAS 1997年第15期1313-1317,共5页
NICOTINIC acetylcholine receptor (AChR) is a pentameric complex (α<sub>2</sub>βγ/εδ), which is com-posed of four different subunits; its expression is regulated by neurally evoked electrical activ... NICOTINIC acetylcholine receptor (AChR) is a pentameric complex (α<sub>2</sub>βγ/εδ), which is com-posed of four different subunits; its expression is regulated by neurally evoked electrical activi-ty. Before innervation in skeletal muscle during embryonic stage, AChR is expressed on thefiber surface; after synaptic formation, the expression of AChR is restricted to the motor end-plate. Denervation of the neonate or blockage of the electrical activity by sodium channel in- 展开更多
关键词 protein kinase C MYOGENIN ACHR γ-promoter depolarization excitation-transcription coupling.
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