Determined Reverberant Blind Source Separation of Audio Mixing Signals

Audio signal separation is an open and challenging issue in the classical“Cocktail Party Problem”.Especially in a reverberation environment,the separation of mixed signals is more difficult separated due to the influence of reverberation and echo.To solve the problem,we propose a determined reverberant blind source separation algorithm.The main innovation of the algorithm focuses on the estimation of the mixing matrix.A new cost function is built to obtain the accurate demixing matrix,which shows the gap between the prediction and the actual data.Then,the update rule of the demixing matrix is derived using Newton gradient descent method.The identity matrix is employed as the initial demixing matrix for avoiding local optima problem.Through the real-time iterative update of the demixing matrix,frequency-domain sources are obtained.Then,time-domain sources can be obtained using an inverse short-time Fourier transform.Experi-mental results based on a series of source separation of speech and music mixing signals demonstrate that the proposed algorithm achieves better separation performance than the state-of-the-art methods.In particular,it has much better superiority in the highly reverberant environment.

Climate Warming Mitigation from Nationally Determined Contributions

Individual countries are requested to submit nationally determined contributions(NDCs)to alleviate global warming in the Paris Agreement.However,the global climate effects and regional contributions are not explicitly considered in the countries’decision-making process.In this study,we evaluate the global temperature slowdown of the NDC scenario(ΔT=0.6°C)and attribute the global temperature slowdown to certain regions of the world with a compact earth system model.Considering reductions in CO_(2),CH_(4),N_(2)O,BC,and SO_(2),the R5OECD(the Organization for Economic Co-operation and Development in 1990)and R5ASIA(Asian countries)are the top two contributors to global warming mitigation,accounting for 39.3%and 36.8%,respectively.R5LAM(Latin America and the Caribbean)and R5MAF(the Middle East and Africa)followed behind,with contributions of 11.5%and 8.9%,respectively.The remaining 3.5%is attributed to R5REF(the Reforming Economies).Carbon Dioxide emission reduction is the decisive factor of regional contributions,but not the only one.Other greenhouse gases are also important,especially for R5MAF.The contribution of short-lived aerosols is small but significant,notably SO_(2)reduction in R5ASIA.We argue that additional species beyond CO_(2)need to be considered,including short-lived pollutants,when planning a route to mitigate climate change.It needs to be emphasized that there is still a gap to achieve the Paris Agreement 2-degree target with current NDC efforts,let alone the ambitious 1.5-degree target.All countries need to pursue stricter reduction policies for a more sustainable world.

KT Boundary Chromites Determined to be Terrestrial:Cr Isotopic Evidence for Excavation and Ejection of Mafic/Ultramafic Rocks by the KT Boundary Impact

Evidence for a mantle and/or basaltic component in KT boundary distal ejecta is apparently inconsistent with ejection from Chicxulub Crater since it is located on;5km thick continental crust（De Paolo et al.,1983;Montanari et al.,1983;Hildebrand and Boynton,1988,1990）.Evidence for mafic/ultramafic target rocks was reinforced by discovery of chromites,some with shock planar deformation features（PDF）,in impact layer samples from sites in southern Colorado and eastern Wyoming（Bohor et al.,1990）.However,until now it was unclear whether the chromites originated with an impactor or with terrestrial target rocks.To this end,high-precision 54Cr/52Cr isotope ratios were measured on KT boundary chromites along with known terrestrial chromites.We find a terrestrial 54Cr/52Cr ratio in KT boundary chromites from impact layer samples collected at the above sites over the last several years（Fig.1）.Ejected terrestrial chromites suggest the impact sampled terrestrial mafic and/or ultramafic target rocks not known to exist in the Chicxulub target area.

Carrier Dynamics Determined by Carrier-Phonon Coupling in InGaN/GaN Multiple Quantum Well Blue Light Emitting Diodes

Phonon sidebands in the electrolumiescence(EL) spectra of InGaN/GaN multiple quantum well blue light emitting diodes are investigated. S-shaped injection current dependence of the energy spacing(ES) between the zero-phonon and first-order phonon-assisted luminescence lines is observed in a temperature range of 100–150 K.The S-shape is suppressed with increasing temperature from 100 to 150 K, and vanishes at temperature above200 K. The S-shaped injection dependence of ES at low temperatures could be explained by the three stages of carrier dynamics related to localization states:(i) carrier relaxation from shallow into deep localization states,(ii) band filling of shallow and deep localization states, and(iii) carrier overflow from deep to shallow localization states and to higher energy states. The three stages show strong temperature dependence. It is proposed that the fast change of the carrier lifetime with temperature is responsible for the suppression of S-shaped feature.The proposed mechanisms reveal carrier recombination dynamics in the EL of InGaN/GaN MQWs at various injection current densities and temperatures.

The Structural Stability of Alpha-Helix Determined by the Preference of Amino Acids

To accomplish their functions, proteins have to achieve different conformations accompanied by conformational transitions. However, the relationship between the preference of amino acids and the stability of the secondary structure is still unclear. Here we perform molecular simulations on a series of helical structures. Our data show that the dissociation energy of the helical structure is related to the preference of amino acids, and the electrostatic repulsion of the residue i and i ＋ 3/4 with the same sign of charge destabilizes the alpha helix.

Rectification of Ion Current Determined by the Nanopore Geometry:Experiments and Modelling

We provide a way to precisely control the geometry of a SiNx nanopore by adjusting the applied electric pulse. The pore is generated by applying the current pulse across a SiNx membrane, which is immersed in potassium chloride solution. We can generate single conical and cylindrical pores with different electric pulses. A theoretical model based on the Poisson and Nernst-Planck equations is employed to simulate the ion transport properties in the channel. In turn, we can analyze pore geometries by fitting the experimental current-voltage （I-V） curves. for the conical pores with a pore size of 0.5-2nm in diameter, the slope angles are around -2.5% to -10%. Moreover, the pore orifice can be enlarged slightly by additional repeating pulses. The conic pore lumen becomes close to a cylindrical channel, resulting in a symmetry I-V transport under positive and negative biases. A qualitative understanding of these effects will help us to prepare useful solid-nanopores as demanded.

Comparing and evaluating the nationally determined contributions of the top six emitters under the Paris Agreement goals

Comparing and evaluating the Nationally Determined Contribution(NDC) is an important element in global stocktake in the post-Paris climate negotiations, aimed at closing the emissions gap with the Paris Agreement goals. To date, however, there has still been no explicit guideline or method. By applying emissions allowance allocated by 16 schemes as benchmarks, this paper tries to compare and evaluate the NDCs of the top six emitters, which jointly account for about 70% of the world's CO_2 emissions. Results show that the four developed countries' NDCs lack ambition with respect to most allocations under 2℃ and all under 1.5℃, indicating they need to substantially ratchet up their NDCs and lead elevating mitigation. Evaluating cumulative emissions is more likely to clarify the ambition and fairness of China's NDC. If considering cumulative emissions, China's NDC is aligned with the median of cumulative allowances under 2℃ and within the 1.5℃ range. The Paris Agreement invited the Parties to communicate the mid-century low emissions strategies. This paper also tries to explore the mid-century mitigation in the perspective of allocations, which might provide decision-makers with some useful information when envisaging the post-NDC mitigation.

Electronic and Optical Properties of TiS2 Determined from Generalized Gradient Approximation Study

The electronic and optical properties of TiS2 are studied of density functional theory. A linearized and augmented by using an ab-initio calculation within the frame plane wave basis set with the generalized gradient approximation as proposed by Perdew et al. is used for the energy exchange-correlation determination. The results show a metallic character of TiS2, and the plots of total and partial densities of states of TiS2 show the metallic character of the bonds and a strong hybridization between the states d of Ti and p of S below the Fermi energy. The optical properties of the material such as real and imaginary parts of dielectric constant （ε（w） = ε1（w） ＋ iε2（w））, refractive index n（w）, optical reflectivity R（w）, for E / /x and E / /z are performed for the energy range of 0-.14 eV.

Estimation of Acute Toxicity of Ammonium Sulphate to the Fresh Water Catfish,Heteropneustes fossilis——Ⅰ.Analysis of LC_(50) Values Determined by Various Methods

The acute toxic effects of ammonium sulphate to fresh-water catfish, Heteropneustes fossilis (H.fossilis) have been studied by determining LC50 values with 95% confidence limits, by the graphic method, the logistic method, the Spearman and Karber method and the trimmed Spearman-Karber method. The trimmed Spearman-Karber method was found the most ideal for ammonium salt toxicity test. The flaws in the trimmed Spearman-Karber method are also discussed.

The Chromosomal Effect of Birchen Dust as Determined by the Micronucleus Test

In a wood processing factory, the measured air concentration of birchen dust was 1. 26 ±0. 41 mg/m3, and the micronucleus frequency of peripheral blood lymphocytes in 83 workersexposed to wood dust was 1. 13 ± 2. 83%, which was significantly higher (P < 0.01 ) thanthat of control group (0. 51 ± 1. 41% ). The number of exposed workers with positive mi-cronucleus test was 9. 6 %, which was higher than that of control group (4. 5 % ), but thedifference was not significant (P >0. 05 ). The micronucleus test in mice treated with waterextracts of unsteamed and unbaked birchen dust showed that the micronucleus frequencies inall treated groups were significantly higher than that of contro group (P < 0. 01 ) and therewas also a doseresponse correlation (r = 0. 96, P < 0. 0005 ). The results of steamed andbaked birchen dust extracts were significantly lower than those of the unsteamed and unbakedones at the same doses (P< 0. 001 ). This suggests that when the birchen dust is steamed atthe temperature of 100℃ for 24h or baked at the temperature of 80℃, its inducing effect inmicronucleus test could be lowered

Determined to Reform

IN November, the Third Plenary Session of the 18th Central Committee of the Communist Party of China （CPC） undoubtedly proved to be the most noteworthy event in China. Deciding the country＇s direction for the next five to 10 years, the meeting＇s significance is no less than that of the Third Plenary Session of the 11th CPC Central Committee in 1978, where the reform and opening up policy was drawn up. Currently,

How the Soul Boy of The 10th Bainqen Is Determined

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Offspring Sex Is Not Determined by Gestation Temperature in a Viviparous Lizard(Eremias multiocellata) from the Desert Steppe of Inner Mongolia

Sex-determining systems show a striking diversity not only among species, but also among popula tions. In reptiles, sex-determina tion is a continuum, from tempera ture-dependent sex determination(TSD) to genetic sex determination(GSD).The multi-ocellated racerunner(Eremias multiocellata)is reported to be a cryptic ZZ/ZW chromosomal TSD species, with male-biased sex ratios at high temperatures in two Gansu populations. However, the generality of the sex-determining pattern in different populations of this species remains unclear. To investigate the mode of sex determina tion in a popula tion of E.multiocellata from the desert steppe of Inner Mongolia,we first identified sex chromosomes via comparative genomic hybridization(CGH). We then conducted a thermal manipulation experiment to determine the effect of gestation temperature on offspring sex ratios.From the CGH studies we found that lizards from the Inner Mongolia population possessed ZZ/ZW sex chromosomes. However, our thermal manipulation experiment showed that gestation temperature did not affect the sex ratio of neonates in this population. In combination, these results rule out TSD in the Inner Mongolia population of E. multiocellata, and suggest that there is widespread geographic variation in the sexdetermining system of this species.

Comparison of Highly-Weathered Acid Soil CEC Determined by NH₄OAc (pH = 7.0) Exchange Method and BaCl₂-MgSO₄Forced-Exchange Method

Cation exchange capacity (CEC) is one of the most important properties of soils. The NH4OAc (pH = 7.0) exchange method is usually recommended to determine CEC (CEC1) of all soils with different pH values, particularly for studies on soil taxonomy. But comparatively the BaCl2-MgSO4 forced-exchange method is more authentic in determining CEC (CEC2) of tropical and subtropical highly-weathered acid soils. But so far little is known about the difference between CEC1 and CEC2. In this study, the physiochemical data of 114 acid B horizon soils from 112 soil series of tropical and subtropical China were used, CEC1 and CEC2 were determined and compared, the influencing factors were analyzed for the difference between CEC1 and CEC2, and then a regression model was established between CEC1 and CEC2. The results showed that CEC2 was significantly lower than CEC1 (p < 0.01), CEC2 was 14.76% - 63.31% with a mean of 36.32% of CEC1. In view of the contribution to CEC from other properties, CEC2 was mainly determined by pH (45.92%), followed by silt (21.05%), free Fe2O3 (17.35%) and clay contents (12.76%), CEC1 was mainly decided by free Fe2O3 content (40.38%), followed by pH (28.39%) and silt content (27.29%;and the difference between CEC1 and CEC2 was mainly affected by free Fe2O3 (50.92%), followed by silt content (26.46%) and pH (21.80%). The acceptable optimal regression model between CEC2 and CEC1 was established as CEC2 = 2.3114 × CEC11.1496 (R2 = 0.410, P < 0.001, RMSE = 0.15). For the studies on soil taxonomy, the BaCl2-MgSO4 forced-exchange method is recommended in determining CEC of the highly-weathered acid soils in the tropical and subtropical regions.

Uncertainty of temperature rise under nationally determined contributions and carbon neutral policies

Nationally determined contributions raised by Paris Agreement aim to control the temperature rise below 2°C or even 1.5°C at the end of the 21st century,compared to pre-industrial levels.However,the climate response of the Nationally Determined Contributions(NDCs)remains uncertain due to unstable policies and their credibility.In this study,we calculated the uncertainty of global temperature rise caused by uncertain NDCs and carbon-neutral policies and discussed the difficulty of policy implementation.The results show that there will be 8 GtC uncertainty in emission at the end of the 21st century,responsible for the temperature rise of 0.37°C(1.73–2.10°C).A delayed policy in emission reduction by major emitters would result in a temperature rise of over 2°C,while under non-delay policy,the 2°C target will be possibly achieved.Besides,low-emission countries would introduce a 30 GtC cumulative emission uncertainty at the end of the 21st century if there are no restrictions,leading to a 0.3°C global warming uncertainty.Developed countries need more substantial reductions in carbon intensity to achieve their climate policies while developing countries are under less pressure.The reduction of carbon intensity requires the strengthening of technical and economic methods.This study provides a reference for the realization of emission policies and temperature rise targets.

Sufficient or insufficient: Assessment of the intended nationally determined contributions (INDCs) of the world's major greenhouse gas emitters

The recent Conference of the Parties of the United Nations Framework Convention on Climate Change has resulted in the submission of the Intended Nationally Determined Contributions (INDCs) of 190 countries. This study aims to provide an analysis of the ambitiousness and fairness of the mitigation components of the INDCs submitted by various parties. We use a unified framework to assess 23 INDCs that cover 50 countries, including European Union (EU)-28 countries as parties to the Convention, which represent 87.45% of the global greenhouse gas emissions in 2012. First, we transform initial INDC files into reported reduction targets. Second, we create four schemes and six scenarios to determine the required reduction effort, which considers each nation's reduction responsibility, capacity, and potential, thereby reflecting their historical and current development status. Finally, we combine the reported reduction target and the required reduction effort to assess INDCs. Evaluation results of the 23 emitters indicate that 2 emitters (i.e., EU and Brazil) are rated as "sufficient," 7 emitters (e.g., China, the United States, and Canada) are rated as "moderate," and 14 emitters (e.g., India, Russia, and Japan) are rated as "insufficient." Most pledges exhibit a considerable distance from representing a fair contribution.

Human rhinovirus C infection is associated with asthma in children determined by x TAG respiratory viral panel FAST

Dear Editor,Cumulative evidence supports the role of early-life viral infections,especially respiratory syncytial virus(RSV)and human rhinovirus(HRV),as major antecedents of childhood asthma(Lemanske,2002;Jackson et al.,2008).In this study,the x TAG respiratory viral panel FAST(RVP FAST)assay,a multiplex polymerase chain reaction(PCR)-based method(Arens et al.,2010;BaladaLlasat et al.,2011;Gharabaghi et al.,2011;Selvaraju,2012),was used to investigate the association of infec-

DETERMINE评分与急性心肌梗死PCI术预后关系的分析

探讨DETERMINE评分(病理性Q波导联数*2+碎裂QRS波导联数+T波倒置导联数)与急性心肌梗死患者经皮冠状动脉介入(PCI)术后预后的关系。方法 选择2021.1-2022.12在我院住院接受PCI治疗的急性心肌梗死患者206例,根据预后情况分为预后良好组(165例)和预后不良组(41例)。比较两组患者的临床资料及DETERMINE评分,采用多因素Logistic回归法分析影响急性心肌梗死PCI术后预后的相关因素;创建受试者工作特征曲线(ROC),分析DETERMINE评分对急性心肌梗死PCI术后预后的预测价值。分析急性心肌梗死PCI术预后不良的影响因素。结果 与预后良好组比较,预后不良组糖尿病史、心律失常史比例及DETERMINE评分、年龄、体重指数、左室射血分数、糖化血红蛋白、低密度脂蛋白胆固醇、总胆固醇水平均显著升高,差异具有统计学意义;二元Logistic回归分析显示DETERMINE评分、心律失常史、体重指数、糖化血红蛋白、低密度脂蛋白胆固醇是冠心病患者PCI手术预后不良的独立危险因素(OR=1.443~15.658,P<0.05)。结论 DETERMINE评分与冠心病PCI术预后相关,需引起临床关注。