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Hemoglobin loss method calculates blood loss during pancreaticoduodenectomy and predicts bleeding-related risk factors
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作者 Chao Yu Yi-Min Lin Guo-Zhe Xian 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第2期419-428,共10页
BACKGROUND The common clinical method to evaluate blood loss during pancreaticoduoden-ectomy(PD)is visual inspection,but most scholars believe that this method is extremely subjective and inaccurate.Currently,there is... BACKGROUND The common clinical method to evaluate blood loss during pancreaticoduoden-ectomy(PD)is visual inspection,but most scholars believe that this method is extremely subjective and inaccurate.Currently,there is no accurate,objective me-thod to evaluate the amount of blood loss in PD patients.We retrospectively analyzed the clinical data of 341 patients who underwent PD in Shandong Provincial Hospital from March 2017 to February 2019.According to different surgical methods,they were divided into an open PD(OPD)group and a laparoscopic PD(LPD)group.The differences and correlations between the in-traoperative estimation of blood loss(IEBL)obtained by visual inspection and the intraoperative calculation of blood loss(ICBL)obtained using the Hb loss method were analyzed.ICBL,IEBL and perioperative calculation of blood loss(PCBL)were compared between the two groups,and single-factor regression analysis was performed.RESULTS There was no statistically significant difference in the preoperative general patient information between the two groups(P>0.05).PD had an ICBL of 743.2(393.0,1173.1)mL and an IEBL of 100.0(50.0,300.0)mL(P<0.001).There was also a certain correlation between the two(r=0.312,P<0.001).Single-factor analysis of ICBL showed that a history of diabetes[95%confidence interval(CI):53.82-549.62;P=0.017]was an independent risk factor for ICBL.In addition,the single-factor analysis of PCBL showed that body mass index(BMI)(95%CI:0.62-76.75;P=0.046)and preoperative total bilirubin>200μmol/L(95%CI:7.09-644.26;P=0.045)were independent risk factors for PCBL.The ICBLs of the LPD group and OPD group were 767.7(435.4,1249.0)mL and 663.8(347.7,1138.2)mL,respectively(P>0.05).The IEBL of the LPD group 200.0(50.0,200.0)mL was slightly greater than that of the OPD group 100.0(50.0,300.0)mL(P>0.05).PCBL was greater in the LPD group than the OPD group[1061.6(612.3,1632.3)mL vs 806.1(375.9,1347.6)mL](P<0.05).CONCLUSION The ICBL in patients who underwent PD was greater than the IEBL,but there is a certain correlation between the two.The Hb loss method can be used to evaluate intraoperative blood loss.A history of diabetes,preoperative bilirubin>200μmol/L and high BMI increase the patient's risk of bleeding. 展开更多
关键词 PANCREATICODUODENECTOMY Hemoglobin loss Calculated blood loss Estimated blood loss
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Numerical study of alpha particle loss with toroidal field ripple based on CFETR steady-state scenario
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作者 李钮琦 徐颖峰 +1 位作者 钟方川 张德兵 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第1期503-510,共8页
Effects of plasma equilibrium parameters on the alpha particle loss with the toroidal field ripple based on the CFETR steady-state scenario have been numerically investigated by the orbit-following code GYCAVA. It is ... Effects of plasma equilibrium parameters on the alpha particle loss with the toroidal field ripple based on the CFETR steady-state scenario have been numerically investigated by the orbit-following code GYCAVA. It is found that alpha particle losses decrease and loss regions become narrower with the plasma current increasing or with the magnetic field decreasing. It is because the ripple stochastic transport and the ripple well loss of alpha particle are reduced with the safety factor decreasing. Decrease of the plasma density and temperature can reduce alpha particle losses due to enhancement of the slowing-down effect. The direction of the toroidal magnetic field can significantly affect heat loads induced by lost alpha particle. The vertical asymmetry of heat loads induced by the clockwise and counter-clockwise toroidal magnetic fields are due to the fact that the ripple distribution is asymmetric about the mid-plane, which can be explained by the typical orbits of alpha particle. The maximal heat load of alpha particle for the clockwise toroidal magnetic field is much smaller than that for the counter-clockwise one. 展开更多
关键词 alpha particle loss RIPPLE orbit-following TOKAMAK
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Genetically modified pigs:Emerging animal models for hereditary hearing loss
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作者 Xiao Wang Tian-Xia Liu +7 位作者 Ying Zhang Liang-Wei Xu Shuo-Long Yuan A-Long Cui Wei-Wei Guo Yan-Fang Wang Shi-Ming Yang Jian-Guo Zhao 《Zoological Research》 SCIE CSCD 2024年第2期284-291,共8页
Hereditary hearing loss(HHL),a genetic disorder that impairs auditory function,significantly affects quality of life and incurs substantial economic losses for society.To investigate the underlying causes of HHL and e... Hereditary hearing loss(HHL),a genetic disorder that impairs auditory function,significantly affects quality of life and incurs substantial economic losses for society.To investigate the underlying causes of HHL and evaluate therapeutic outcomes,appropriate animal models are necessary.Pigs have been extensively used as valuable large animal models in biomedical research.In this review,we highlight the advantages of pig models in terms of ear anatomy,inner ear morphology,and electrophysiological characteristics,as well as recent advancements in the development of distinct genetically modified porcine models of hearing loss.Additionally,we discuss the prospects,challenges,and recommendations regarding the use pig models in HHL research.Overall,this review provides insights and perspectives for future studies on HHL using porcine models. 展开更多
关键词 PIGS Animal models Hereditary hearing loss Genetic modification Inner ear
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An Improved Solov2 Based on Attention Mechanism and Weighted Loss Function for Electrical Equipment Instance Segmentation
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作者 Junpeng Wu Zhenpeng Liu +2 位作者 Xingfan Jiang Xinguang Tao Ye Zhang 《Computers, Materials & Continua》 SCIE EI 2024年第1期677-694,共18页
The current existing problem of deep learning framework for the detection and segmentation of electrical equipment is dominantly related to low precision.Because of the reliable,safe and easy-to-operate technology pro... The current existing problem of deep learning framework for the detection and segmentation of electrical equipment is dominantly related to low precision.Because of the reliable,safe and easy-to-operate technology provided by deep learning-based video surveillance for unmanned inspection of electrical equipment,this paper uses the bottleneck attention module(BAM)attention mechanism to improve the Solov2 model and proposes a new electrical equipment segmentation mode.Firstly,the BAM attention mechanism is integrated into the feature extraction network to adaptively learn the correlation between feature channels,thereby improving the expression ability of the feature map;secondly,the weighted sum of CrossEntropy Loss and Dice loss is designed as the mask loss to improve the segmentation accuracy and robustness of the model;finally,the non-maximal suppression(NMS)algorithm to better handle the overlap problem in instance segmentation.Experimental results show that the proposed method achieves an average segmentation accuracy of mAP of 80.4% on three types of electrical equipment datasets,including transformers,insulators and voltage transformers,which improve the detection accuracy by more than 5.7% compared with the original Solov2 model.The segmentation model proposed can provide a focusing technical means for the intelligent management of power systems. 展开更多
关键词 Deep learning electrical equipment attention mechanism weighted loss function
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Navigating Silence: A Comprehensive Review of Parental Roles in the Rehabilitation of Children with Hearing Loss
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作者 Kondwani Hamanjila Marirajan Thiruppathi Harrison Phiri 《Open Journal of Pediatrics》 2024年第2期364-378,共15页
This narrative literature review delves into the multifaceted realm of parental involvement in the rehabilitation of children with permanent hearing loss. While existing research has made strides in elucidating parent... This narrative literature review delves into the multifaceted realm of parental involvement in the rehabilitation of children with permanent hearing loss. While existing research has made strides in elucidating parental roles in this context, critical gaps persist, necessitating a comprehensive exploration to inform future endeavors. Our review synthesizes a wide array of studies, identifying these gaps and emphasizing the significance of addressing them. Themes emerging from the literature include the varying degrees of parental engagement, the impact of cultural and socio-economic factors, and the challenges faced by families navigating rehabilitation processes. The synthesis of this literature not only highlights the current state of knowledge but also provides a roadmap for future research efforts. By addressing these gaps, we aim to contribute to a more nuanced understanding of parental involvement in the rehabilitation of children with permanent hearing loss, ultimately fostering improved support systems and holistic care for affected families. 展开更多
关键词 Parental Involvement REHABILITATION CHILDREN Permanent Hearing loss Socioeconomic Factors Cultural Influences
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Modified intratympanic steroid therapy for sudden sensorineural hearing loss via tympanic tube and gelfoam as a salvage treatment
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作者 Sichao Liang Yunshuo Li +6 位作者 Zhenping Guo Manlin Lu Xin Li Jia Xu Wenjing Chen Juanjuan Gao Haijin Yi 《Journal of Otology》 CAS CSCD 2024年第1期19-23,共5页
Background: Sudden sensorineural hearing loss(SSNHL) is a prevalent emergency in ear, nose, and throat practice. Previous studies have demonstrated that intratympanic steroid therapy(IST) can serve as a salvage treatm... Background: Sudden sensorineural hearing loss(SSNHL) is a prevalent emergency in ear, nose, and throat practice. Previous studies have demonstrated that intratympanic steroid therapy(IST) can serve as a salvage treatment for SSNHL after the failure of systemic steroid therapy(SST).Objective: This study aimed to analyze the efficacy of modified IST involving the insertion of a tympanic tube and gelfoam as a salvage treatment for patients with SSNHL, and to explore its associated factors.Methods: Totally, 74 patients who were aged 22–81 years with SSNHL were enrolled and allocated to either the control group(n = 25) or the treatment group(n = 49) based on their treatment modalities. All patients received SST lasting for at least 7 days. Subsequently, patients in the treatment group, after SST failure, underwent IST twice a week for 2–6 weeks, while the control group did not. Efficacy was assessed by the improvement in pure tone average at the affected frequency at the beginning and end of IST.Results: Hearing improvement in all patients after IST in the treatment group was 9.71 ± 14.84 dB, with significant improvement at affected frequencies(250-8000 Hz) compared with the control group(P < 0.05). The findings indicated the duration from the onset of SSNHL to the beginning of IST as an independent factor for pure tone average improvement after treatment(P = 0.002), whereas age, duration of SST, and time of IST were not(P > 0.05).Conclusion: The modified IST was demonstrated to be a safe and effective method as a salvage treatment for SSNHL. This study explored the efficacy of a modified IST approach, incorporating the utilization of tympanic tubes and gelfoam as key components. The findings underscore the advantages of gelfoam as a strategic drug carrier placed in the round window niche. By minimizing drug loss, extending action time, and increasing perilymph concentration, gelfoam enhances the therapeutic impact of IST, contributing to improved hearing outcomes in patients with SSNHL. 展开更多
关键词 Modified intratympanic steroid therapy Sudden sensorineural hearing loss GELFOAM Tympanic tube
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Systemic Inflammation Response Index and weight loss as prognostic factors in metastatic pancreatic cancer: A concept study from the PANTHEIA-SEOM trial
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作者 Vilma Pacheco-Barcia Sara Custodio-Cabello +7 位作者 Fatima Carrasco-Valero Magda Palka-Kotlowska Axel Mariño-Mendez Alberto Carmona-Bayonas Javier Gallego A J Muñoz Martín Paula Jimenez-Fonseca Luis Cabezon-Gutierrez 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第2期386-397,共12页
BACKGROUND The prognostic value of the Systemic Inflammation Response Index(SIRI)in advanced pancreatic cancer is recognized,but its correlation with patients´nutritional status and outcomes remains unexplored.AI... BACKGROUND The prognostic value of the Systemic Inflammation Response Index(SIRI)in advanced pancreatic cancer is recognized,but its correlation with patients´nutritional status and outcomes remains unexplored.AIM To study the prognostic significance of SIRI and weight loss in metastatic pancreatic cancer.METHODS The PANTHEIA-Spanish Society of Medical Oncology(SEOM)study is a multicentric(16 Spanish hospitals),observational,longitudinal,non-interventional initiative,promoted by the SEOM Real World-Evidence work group.This pilot study sought to analyze the association between weight loss and inflammatory status as defined by SIRI.The cohort stems from a proof-of-concept pilot study conducted at one of the coordinating centers.Patients with pathologically confirmed metastatic pancreatic adenocarcinoma,treated from January 2020 to January 2023,were included.The index was calculated using the product of neutrophil and monocyte counts,divided by lymphocyte counts,obtained within 15 days before initiation chemotherapy.This study evaluated associations between overall survival(OS),SIRI and weight loss.RESULTS A total of 50 patients were included.66%of these patients were male and the median age was 66 years.Metastasis sites:36%liver,12%peritoneal carcinomatosis,10%lung,and 42%multiple locations.Regarding the first line palliative chemotherapy treatments:50%received gemcitabine plus nab-paclitaxel;28%,modified fluorouracil,leucovorin,irinotecan and oxaliplatin,and 16%were administered gemcitabine.42%had a weight loss>5%in the three months(mo)preceding diagnosis.21 patients with a SIRI≥2.3×10^(3)/L exhibited a trend towards a lower median OS compared to those with a SIRI<2.3×10^(3)/L(4 vs 18 mo;P<0.000).Among 21 patients with>5%weight loss before diagnosis,the median OS was 6 mo,in contrast to 19 mo for those who did not experience such weight loss(P=0.003).Patients with a weight loss>5%showed higher SIRI levels.This difference was statistically significant(P<0.000).For patients with a SIRI<2.3×10^(3)/L,those who did not lose>5%of their weight had an OS of 20 mo,compared to 11 mo for those who did(P<0.001).No association was found between carbohydrate antigen 19-9 levels≥1000 U/mL and weight loss.CONCLUSION A higher SIRI was correlated with decreased survival rates in patients with metastatic pancreatic cancer and associated with weight loss.An elevated SIRI is suggested as a predictor of survival,emphasizing the need for prospective validation in the upcoming PANTHEIA-SEOM study. 展开更多
关键词 Pancreatic cancer NUTRITION Prognostic factor INFLAMMATION Advanced cancer Systemic inflammatory response index Weight loss
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Effect of foot reflexology on an infant with sensorineural hearing loss:A case report
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作者 Yu-Jun Lee Mao-Qing Chen Jie Dong 《World Journal of Clinical Cases》 SCIE 2024年第8期1437-1441,共5页
BACKGROUND Our study contributes to the further understanding of the mechanism of foot reflexology.Foot reflexology has been reported to affect hearing recovery,but no physiological evidence has been provided.This lac... BACKGROUND Our study contributes to the further understanding of the mechanism of foot reflexology.Foot reflexology has been reported to affect hearing recovery,but no physiological evidence has been provided.This lack of evidence hampers the acceptance of the technique in clinical practice.CASE SUMMARY A girl was taken to North Sichuan Medical University Affiliated Hospital for a hearing screen by her parents.Her parents reported that her hearing level was the same as when she was born.The girl was diagnosed with sensorineural hearing loss(SNHL)by a doctor in the otolaryngology department.After we introduced the foot reflexology project,the parents agreed to participate in the experiment.After 6 months of foot reflexology treatment,the hearing threshold of the girl recovered to a normal level,below 30 dB.CONCLUSION Foot reflexology should be encouraged in clinical practice and for families of infants with SNHL. 展开更多
关键词 Infant with sensorineural hearing loss Foot reflexology Functional connectivity Language development Case report
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A Physical Core-Loss Model for Laminated Magnetic Sheet Steels
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作者 Kuofeng Chen 《Journal of Power and Energy Engineering》 2024年第3期115-123,共9页
A full-frequency instant core-loss equation built from the induction physical model of magnetic materials, where the iron loss, eddy loss, and hysteresis loss no longer have an integral term, and this new equation pro... A full-frequency instant core-loss equation built from the induction physical model of magnetic materials, where the iron loss, eddy loss, and hysteresis loss no longer have an integral term, and this new equation provides high simulation accuracy and performs dynamic core loss analysis on non-sinusoidal or pulse magnetic fields. The simulation examples use a high-grade electrical steel sheet 65CS400 by Epstein experimental data covering magnetic field 0.1 - 1.8 T and frequency 50 - 5000 Hz, and the average error of the simulated core loss is less than 4%. Since the simulation is converged by magnetic physical parameters, so the physical relevance of the similar laminated materials can be compared with the coefficient results. . 展开更多
关键词 Core loss Hysteresis loss Electrical Steel Sheet
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Short communication:Extreme glacier mass loss triggered by high temperature and drought during hydrological year 2022/2023 in Qilian Mountains
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作者 JiZu Chen XingYu Xue WenTao Du 《Research in Cold and Arid Regions》 CSCD 2024年第1期1-4,共4页
In the hydrological year 2022/2023,the glaciers in the Qilian Mountains experienced unprecedented mass loss.The glacier-wide mass balance was-1,188 mm w.e.,in contrast to-350 mm of average mass balance since 1990 over... In the hydrological year 2022/2023,the glaciers in the Qilian Mountains experienced unprecedented mass loss.The glacier-wide mass balance was-1,188 mm w.e.,in contrast to-350 mm of average mass balance since 1990 over the Bailanghe Glacier No.12 in the middle of Qilian Mountains.The temperature during 2022–2023 reached the highest value ever recorded,second only to 2022,while at the same time the precipitation amount was less compared to other year since 2000,which together led to the strongest glacier mass loss during 2022–2023.The atmospheric circulation analysis shows that the high temperature in the Qilian Mountains in 2023 was jointly caused by the Arctic air mass and East Asian monsoon. 展开更多
关键词 Bailanghe Glacier No.21 Glacier mass loss Extreme high temperature Atmospheric circulation
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Prevalence of Noise-Induced Hearing Loss Related to the Mills in the Markets of the Municipality of Parakou in 2021
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作者 Fatiou Alabi Bouraïma Cocouvi Bruno Ametonou +5 位作者 Ulrich Bidossèssi Vodouhe François Avakoudjo Jorelle Wafo Marius Claude Flatin Spéro H. R. Hounkpatin Wassi Adjibabi 《International Journal of Otolaryngology and Head & Neck Surgery》 2024年第1期1-10,共10页
Introduction: Noise is the second leading cause of hearing loss in adults after presbycusis. The objective of this work was to study hearing loss induced by the noise of mills in the markets of Parakou. Methods: This ... Introduction: Noise is the second leading cause of hearing loss in adults after presbycusis. The objective of this work was to study hearing loss induced by the noise of mills in the markets of Parakou. Methods: This was a descriptive and analytical cross-sectional study, conducted from February 3 to June 3, 2021 in the markets of Parakou. It concerned millers and sellers located within a 5 meter radius around the mills and among whom pure-tone audiometry was performed to detect a hearing loss. Subjects with no particular medical health history, under 55 years of age and having been working in these markets since more than 12 months, were included. Results: In this study, 103 subjects were selected, including 43 millers and 61 sellers. Their average age was 29 ± 13 years. The sex ratio was 0.49. The average length of service in the profession was 8 years with the extremes of 3 months and 47 years. They were exposed to noise on average 10 hours per day and 6 days a week. The average duration of weekly noise exposure was 23 h 28 min ± 13 h 32 min with the extremes of 5 h 00 min and 52 h 30 min. The average level of noise exposure was 90 dB with the extremes of 72 and 110 dB. 24 subjects reported symptoms related to noise such as headache, tinnitus, and hearing loss, with respective proportions of 22.33%, 20.39% and 06.80%. The prevalence of noise-related hearing loss was 26.21% (n = 27/103). Subjects with a notch at 4000 Hz and normal Average Hearing Loss (AHL) (20.39%) had a seven-time greater risk of developing noise-induced hearing loss (OR = 6.58;95% CI [2.54 - 18.8], p Conclusion: Hearing loss related to the noise of mills affected both millers and sellers near the mills in markets, hence the importance of regulating mills. 展开更多
关键词 Noise-Induced Hearing loss MILLS MARKETS Parakou
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Real-Time Fracture Aperture Identification Using Mud Loss Data and Solution for LCM Combination
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作者 Hongpeng Yang Yong Lin Na Jiang 《Journal of Applied Mathematics and Physics》 2024年第4期1337-1351,共15页
Managing server lost circulation is a major challenge of drilling operation in naturally fractured formations and it causes much nonproductive rig time. When encountered with loss, the fracture aperture intersecting t... Managing server lost circulation is a major challenge of drilling operation in naturally fractured formations and it causes much nonproductive rig time. When encountered with loss, the fracture aperture intersecting the wellbore is not well-identified in time, which has a significant impact on the decision of drilling operation and the undesired result of loss curing. Therefore, the onset of fracture is identified in a timely manner and evaluated comprehensively to formulate an appropriate strategy over time. However, the mud loss date, which is the primary source of information retrieved from the drilling process, was not properly used in real-time prediction of fracture aperture. This article provides a detailed mathematical study to discuss the mechanism of mud invasion in the near-wellbore region and prediction of fracture aperture. The fracture aperture can be calculated from mud-loss data by solving a cubic equation with input parameters given by the well radius, the overpressure ratio, and the maximum mud-loss volume. It permits the proper selection of loss-circulation material (LCM) with respect to particle size distribution and fiber usage. The case study illustrates the applicability of this methodology with a discussion on LCM particle distribution in different scenarios and the result demonstrates the outcome of inappropriate LCM usage and the advantages of the novel fiber-based LCM treatment. 展开更多
关键词 Mud loss Fracture Aperture LCM Selection Particle-Size Distribution
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Loss to Specialized Cardiology Follow-Up in Adults Living with Congenital Heart Disease
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作者 Cheryl Dickson Danielle Osborn +3 位作者 David Baker Judith Fethney David S.Celermajer Rachael Cordina 《Congenital Heart Disease》 SCIE 2024年第1期49-63,共15页
Background:Much has been written about the loss to follow-up in the transition between pediatric and adult Congenital Heart Disease(CHD)care centers.Much less is understood about the loss to follow-up(LTF)after a succ... Background:Much has been written about the loss to follow-up in the transition between pediatric and adult Congenital Heart Disease(CHD)care centers.Much less is understood about the loss to follow-up(LTF)after a successful transition.This is critical too,as patients lost to specialised care are more likely to experience mor-bidity and premature mortality.Aims:To understand the prevalence and reasons for loss to follow-up(LTF)at a large Australian Adult Congenital Heart Disease(ACHD)centre.Methods:Patients with moderate or highly complex CHD and gaps in care of>3 years(defined as LTF)were identified from a comprehensive ACHD data-base.Structured telephone interviews examined current care and barriers to clinic attendance.Results:Overall,407(22%)of ACHD patients(n=1842)were LTF.The mean age at LTF was 31(SD 11.5)years and 54%were male;311(76%)were uncontactable.Compared to adults seen regularly,lost patients were younger,with a greater socio-economic disadvantage,and had less complex CHD(p<0.05 for all).We interviewed 59 patients(14%).The top 3 responses for care absences were“feeling well”(61%),losing track of time(36%),and not needing fol-low-up care(25%).Conclusions:A large proportion of the ACHD population becomes lost to specialised cardiac care,even after a successful transition.This Australian study reports younger age,moderate complexity defects,and socio-economic disadvantage as predictive of loss to follow-up.This study highlights the need for novel approaches to patient-centered service delivery even beyond the age of transition and resources to maintain patient engagement within the ACHD service. 展开更多
关键词 loss to follow-up FOLLOW-UP adult congenital heart disease lapse in care gaps in care care gaps care continuity ACHD predictors
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Dispersed Wind Power Planning Method Considering Network Loss Correction with Cold Weather
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作者 Hanpeng Kou Tianlong Bu +2 位作者 Leer Mao Yihong Jiao Chunming Liu 《Energy Engineering》 EI 2024年第4期1027-1048,共22页
In order to play a positive role of decentralised wind power on-grid for voltage stability improvement and loss reduction of distribution network,a multi-objective two-stage decentralised wind power planning method is... In order to play a positive role of decentralised wind power on-grid for voltage stability improvement and loss reduction of distribution network,a multi-objective two-stage decentralised wind power planning method is proposed in the paper,which takes into account the network loss correction for the extreme cold region.Firstly,an electro-thermal model is introduced to reflect the effect of temperature on conductor resistance and to correct the results of active network loss calculation;secondly,a two-stage multi-objective two-stage decentralised wind power siting and capacity allocation and reactive voltage optimisation control model is constructed to take account of the network loss correction,and the multi-objective multi-planning model is established in the first stage to consider the whole-life cycle investment cost of WTGs,the system operating cost and the voltage quality of power supply,and the multi-objective planning model is established in the second stage.planning model,and the second stage further develops the reactive voltage control strategy of WTGs on this basis,and obtains the distribution network loss reduction method based on WTG siting and capacity allocation and reactive power control strategy.Finally,the optimal configuration scheme is solved by the manta ray foraging optimisation(MRFO)algorithm,and the loss of each branch line and bus loss of the distribution network before and after the adoption of this loss reduction method is calculated by taking the IEEE33 distribution system as an example,which verifies the practicability and validity of the proposed method,and provides a reference introduction for decision-making for the distributed energy planning of the distribution network. 展开更多
关键词 Decentralised wind power network loss correction siting and capacity determination reactive voltage control two-stage model manta ray foraging optimisation algorithm
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Highly Aligned Ternary Nanofiber Matrices Loaded with MXene Expedite Regeneration of Volumetric Muscle Loss
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作者 Moon Sung Kang Yeuni Yu +5 位作者 Rowoon Park Hye Jin Heo Seok Hyun Lee Suck Won Hong Yun Hak Kim Dong‑Wook Han 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第4期269-292,共24页
Current therapeutic approaches for volumetric muscle loss(VML)face challenges due to limited graft availability and insufficient bioactivities.To overcome these limitations,tissue-engineered scaffolds have emerged as ... Current therapeutic approaches for volumetric muscle loss(VML)face challenges due to limited graft availability and insufficient bioactivities.To overcome these limitations,tissue-engineered scaffolds have emerged as a promising alternative.In this study,we developed aligned ternary nanofibrous matrices comprised of poly(lactide-co-ε-caprolactone)integrated with collagen and Ti_(3)C_(2)T_(x)MXene nanoparticles(NPs)(PCM matrices),and explored their myogenic potential for skeletal muscle tissue regeneration.The PCM matrices demonstrated favorable physicochemical properties,including structural uniformity,alignment,microporosity,and hydrophilicity.In vitro assays revealed that the PCM matrices promoted cellular behaviors and myogenic differentiation of C2C12 myoblasts.Moreover,in vivo experiments demonstrated enhanced muscle remodeling and recovery in mice treated with PCM matrices following VML injury.Mechanistic insights from next-generation sequencing revealed that MXene NPs facilitated protein and ion availability within PCM matrices,leading to elevated intracellular Ca^(2+)levels in myoblasts through the activation of inducible nitric oxide synthase(i NOS)and serum/glucocorticoid regulated kinase 1(SGK1),ultimately promoting myogenic differentiation via the m TOR-AKT pathway.Additionally,upregulated i NOS and increased NO–contributed to myoblast proliferation and fiber fusion,thereby facilitating overall myoblast maturation.These findings underscore the potential of MXene NPs loaded within highly aligned matrices as therapeutic agents to promote skeletal muscle tissue recovery. 展开更多
关键词 Ti_(3)C_(2)T_(x)MXene nanoparticle Ternary nanofibrous matrices Myogenesis Regeneration of volumetric muscle loss Next generation sequencing
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Unknown DDoS Attack Detection with Fuzzy C-Means Clustering and Spatial Location Constraint Prototype Loss
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作者 Thanh-Lam Nguyen HaoKao +2 位作者 Thanh-Tuan Nguyen Mong-Fong Horng Chin-Shiuh Shieh 《Computers, Materials & Continua》 SCIE EI 2024年第2期2181-2205,共25页
Since its inception,the Internet has been rapidly evolving.With the advancement of science and technology and the explosive growth of the population,the demand for the Internet has been on the rise.Many applications i... Since its inception,the Internet has been rapidly evolving.With the advancement of science and technology and the explosive growth of the population,the demand for the Internet has been on the rise.Many applications in education,healthcare,entertainment,science,and more are being increasingly deployed based on the internet.Concurrently,malicious threats on the internet are on the rise as well.Distributed Denial of Service(DDoS)attacks are among the most common and dangerous threats on the internet today.The scale and complexity of DDoS attacks are constantly growing.Intrusion Detection Systems(IDS)have been deployed and have demonstrated their effectiveness in defense against those threats.In addition,the research of Machine Learning(ML)and Deep Learning(DL)in IDS has gained effective results and significant attention.However,one of the challenges when applying ML and DL techniques in intrusion detection is the identification of unknown attacks.These attacks,which are not encountered during the system’s training,can lead to misclassification with significant errors.In this research,we focused on addressing the issue of Unknown Attack Detection,combining two methods:Spatial Location Constraint Prototype Loss(SLCPL)and Fuzzy C-Means(FCM).With the proposed method,we achieved promising results compared to traditional methods.The proposed method demonstrates a very high accuracy of up to 99.8%with a low false positive rate for known attacks on the Intrusion Detection Evaluation Dataset(CICIDS2017)dataset.Particularly,the accuracy is also very high,reaching 99.7%,and the precision goes up to 99.9%for unknown DDoS attacks on the DDoS Evaluation Dataset(CICDDoS2019)dataset.The success of the proposed method is due to the combination of SLCPL,an advanced Open-Set Recognition(OSR)technique,and FCM,a traditional yet highly applicable clustering technique.This has yielded a novel method in the field of unknown attack detection.This further expands the trend of applying DL and ML techniques in the development of intrusion detection systems and cybersecurity.Finally,implementing the proposed method in real-world systems can enhance the security capabilities against increasingly complex threats on computer networks. 展开更多
关键词 CYBERSECURITY DDoS unknown attack detection machine learning deep learning incremental learning convolutional neural networks(CNN) open-set recognition(OSR) spatial location constraint prototype loss fuzzy c-means CICIDS2017 CICDDoS2019
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Reading Loss in Arabic Language During COVID-19 in the UAE and Proposed Solutions:The Perspectives of Primary-Grade Arabic Language Teachers
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作者 Karima Almazroui Muhra Albloushi 《Journal of Sociology Study》 2024年第2期107-118,共12页
The COVID-19 pandemic caused significant disruptions in the field of education worldwide,including in the United Arab Emirates.Teachers and students had to adapt to remote learning and virtual classrooms,leading to va... The COVID-19 pandemic caused significant disruptions in the field of education worldwide,including in the United Arab Emirates.Teachers and students had to adapt to remote learning and virtual classrooms,leading to various challenges in maintaining educational standards.The sudden transition to remote teaching could have a negative impact on students’reading abilities,especially in the Arabic language.To gain insight into the unique challenges encountered by Arabic language teachers in the UAE,a survey was conducted to explore their assessment of teaching quality,student-teacher interaction,and learning outcomes amidst the COVID-19 pandemic.The results of the survey revealed a significant decline of student reading abilities and identified several major issues in online Arabic language teaching.These issues included limited interaction between students and teachers,challenges in monitoring students’class participation and performance,and challenges in effectively assessing students’reading skills.The results also demonstrated some other challenges faced by Arabic language teachers,including a lack of preparedness,a lack of subscription to relevant platforms,and a lack of resources for online learning.Several solutions to these challenges are proposed,including reevaluating the balance between depth and breadth in the curriculum,integrating language skills into the curriculum more effectively,providing more comprehensive teacher professional development,implementing student grouping strategies,utilizing retired and expert teachers in specific content areas,allocating time for interventions,and improving support from both teachers and parents to ensure the quality of online learning. 展开更多
关键词 reading loss Arabic language teachers primary grades online learning United Arab Emirates
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Evaluation of Digits-in-Noise Test and Hearing Handicap Inventory for Adults Screening in Patients with Occupational Noise-Induced Hearing Loss
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作者 Zongzhi Shao 《Proceedings of Anticancer Research》 2024年第1期61-65,共5页
Objective:To explore the clinical evaluation role of the Digits-in-Noise(DIN)test and Hearing Handicap Inventory for Adults Screening(HHIA-S)for patients with occupational noise-induced hearing loss and to observe and... Objective:To explore the clinical evaluation role of the Digits-in-Noise(DIN)test and Hearing Handicap Inventory for Adults Screening(HHIA-S)for patients with occupational noise-induced hearing loss and to observe and analyze their application values.Methods:Fifty patients with suspected occupational noise-induced hearing loss were randomly selected from the Department of Otolaryngology at the hospital as the research target.The collection period for the research cases spanned from January 2022 to November 2023,and all patients had a history of noise exposure.The DIN test and HHIA-S were used for hearing examinations,with clinical,comprehensive diagnosis serving as the gold standard to study their diagnostic performance.Results:The compliance rate of the DIN test was 88.00%,the HHIA-S’s compliance rate was 80.00%,and the combined compliance rate was 94.00%.The compliance rate of the DIN test and the combined compliance rates of the patients were statistically significant compared to the clinical gold standard data(P<0.05),while there was no difference between the compliance rate of the HHIA-S and the gold standard(P>0.05).The data shows that the sensitivity of the combined diagnosis is significantly higher than the sensitivity data of the DIN test and HHIA-S examination alone(P<0.05).Its specificity is 100.00%,and the accuracy data of the joint diagnosis in the degree were higher than those of the DIN test alone(P>0.05)and the HHIA-S alone(P<0.05).Conclusion:For patients with occupational noise-induced hearing loss,the joint evaluation of the DIN test and HHIA-S can significantly improve their diagnostic value with high sensitivity and accuracy. 展开更多
关键词 Occupational noise-induced hearing loss Digital speech in noise test Hearing impairment screening scale Application
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基于改进型Softmax Loss损失函数的面部表情识别
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作者 李校林 张鹏飞 +1 位作者 董玉晖 钮海涛 《计算机仿真》 北大核心 2023年第5期234-238,256,共6页
针对面部表情识别中Softmax Loss损失函数类内特征分散、类间特征未分离的问题,提出一种改进型Softmax Loss损失函数ACAM Loss。上述损失函数将优化集中在余弦角度上,在特征与目标权重的余弦夹角加上间隔m,在特征与非目标权重的余弦夹... 针对面部表情识别中Softmax Loss损失函数类内特征分散、类间特征未分离的问题,提出一种改进型Softmax Loss损失函数ACAM Loss。上述损失函数将优化集中在余弦角度上,在特征与目标权重的余弦夹角加上间隔m,在特征与非目标权重的余弦夹角减去间隔m,有效引导网络学习具备类内距离较小、类间距离较大的强区分度特征,同时加大网络训练力度优化输出,以提升分类效果。实验表明,在CK+和JAFFE数据集上,ACAM Loss函数训练模型表情识别准确率分别达到98.87%和98.92%,相比Softmax Loss函数平均增幅分别为1.35%和1.3%,识别准确率处于主流领先水平,验证了改进损失函数的有效性。 展开更多
关键词 面部表情识别 分类 损失函数 加性余弦角度间隔
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Drip fertigation and plant hedgerows significantly reduce nitrogen and phosphorus losses and maintain high fruit yields in intensive orchards 被引量:2
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作者 SONG Ke QIN Qin +5 位作者 YANG Ye-feng SUN Li-juan SUN Ya-fei ZHENG Xian-qing Lü Wei-guang XUE Yong 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2023年第2期598-610,共13页
A field experiment was carried out to evaluate the effects of drip fertigation combined with plant hedgerows on nitrogen and phosphorus runoff losses in intensive pear orchards in the Tai Lake Basin.Nitrogen and phosp... A field experiment was carried out to evaluate the effects of drip fertigation combined with plant hedgerows on nitrogen and phosphorus runoff losses in intensive pear orchards in the Tai Lake Basin.Nitrogen and phosphorus runoff over a whole year were measured by using successional runoff water collection devices.The four experimental treatments were conventional fertilization(CK),drip fertigation(DF),conventional fertilization combined with plant hedgerows(C+H),and drip fertigation combined with plant hedgerows(D+H).The results from one year of continuous monitoring showed a significant positive correlation between precipitation and surface runoff discharge.Surface runoff discharge under the treatments without plant hedgerows totaled 15.86%of precipitation,while surface runoff discharge under the treatments with plant hedgerows totaled 12.82%of precipitation.Plant hedgerows reduced the number of runoff events and the amount of surface runoff.Precipitation is the main driving force for the loss of nitrogen and phosphorus in surface runoff,and fertilization is an important factor affecting the losses of nitrogen and phosphorus.In CK,approximately 7.36%of nitrogen and 2.63%of phosphorus from fertilization entered the surface water through runoff.Drip fertigation reduced the accumulation of nitrogen and phosphorus in the surface soil and lowered the runoff loss concentrations of total nitrogen(TN)and total phosphorus(TP).Drip fertigation combined with plant hedgerows significantly reduced the overall TN and TP losses by 45.38 and 36.81%,respectively,in comparison to the CK totals.Drip fertigation increased the vertical migration depth of nitrogen and phosphorus nutrients and reduced the accumulation of nitrogen and phosphorus in the surface soil,which increased the pear yield.The promotion of drip fertigation combined with plant hedgerows will greatly reduce the losses of nitrogen and phosphorus to runoff and maintain the high fruit yields in the intensive orchards of the Tai Lake Basin. 展开更多
关键词 drip fertigation plant hedgerows surface runoff nitrogen and phosphorus losses fruit yields
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