Several novel highly symmetric carbohydrates bearing a diacylhydrazine framework have been synthesized via a five-step procedure by utilizing D-glucose, D-galactose and D-xylose as the starting materials, respectively...Several novel highly symmetric carbohydrates bearing a diacylhydrazine framework have been synthesized via a five-step procedure by utilizing D-glucose, D-galactose and D-xylose as the starting materials, respectively. The target compounds have been characterized with IR, 1H NMR and elemental analysis.展开更多
Two series of novel anthranilic diamides containing oxime ester and diacylhydrazine moieties were designed and synthesized.Their structures were characterized by melting points,1H NMR,13C NMR and high resolution mass ...Two series of novel anthranilic diamides containing oxime ester and diacylhydrazine moieties were designed and synthesized.Their structures were characterized by melting points,1H NMR,13C NMR and high resolution mass spectrometry（HRMS）.The single crystal structure of compound 7e was determined by X-ray diffraction and their evaluated insecticidal activity against oriental armyworm（Mythimna separata） indicates that some of the compounds exhibited moderate insecticidal activities.Among the 20 compounds,6a and 6b show 100％ larvicidal activity against Mythimna separate Walker at the test concentration of 100 mg/L.展开更多
A variety of novel N-t-butyl-N'-aminocarbonyl-N-(substitute)Benzoylhydrazines containing α-aminoalkylphosphonate groups were synthesized by the addition of N-t-butyl-N- (substituted)benzoylhydrazines to α-isocya...A variety of novel N-t-butyl-N'-aminocarbonyl-N-(substitute)Benzoylhydrazines containing α-aminoalkylphosphonate groups were synthesized by the addition of N-t-butyl-N- (substituted)benzoylhydrazines to α-isocyanatoalkylphosphonates. which were synthesized by the reaction of α-aminoalkylphosphonates with triphosgene in good yields. The structures of products including by-products were confirmed by 1H NMR, 31P NMR. IR, mass spectroscopy- and elemental analysis.展开更多
A series of novel N-tert-butyl-N＇-acyl-5-methyl-1,2,3-thiadiazole-4-carbohydrazides were designed and synthesized. Their structures were characterized by melting points, ^1H NMR, IR, ESI-MS, and elemental analysis. T...A series of novel N-tert-butyl-N＇-acyl-5-methyl-1,2,3-thiadiazole-4-carbohydrazides were designed and synthesized. Their structures were characterized by melting points, ^1H NMR, IR, ESI-MS, and elemental analysis. The bioassay tests indicated that compound 7o exhibited excellent direct anti-TMV activity and induction activity in vivo at 50μg/mL, which was better than that of Ninamycin and tiadinial. Our studies indicated that 1,2,3-thiadiazole was an active substructure for novel pesticide development.展开更多
文摘Several novel highly symmetric carbohydrates bearing a diacylhydrazine framework have been synthesized via a five-step procedure by utilizing D-glucose, D-galactose and D-xylose as the starting materials, respectively. The target compounds have been characterized with IR, 1H NMR and elemental analysis.
基金Supported by the National Natural Science Foundation of China（Nos.21272129,21372133）,the National Basic Research Program of China（No.2010CB126106） and the National Key Technologies R＆D Program of China（No.2011BAE06B05）.
文摘Two series of novel anthranilic diamides containing oxime ester and diacylhydrazine moieties were designed and synthesized.Their structures were characterized by melting points,1H NMR,13C NMR and high resolution mass spectrometry（HRMS）.The single crystal structure of compound 7e was determined by X-ray diffraction and their evaluated insecticidal activity against oriental armyworm（Mythimna separata） indicates that some of the compounds exhibited moderate insecticidal activities.Among the 20 compounds,6a and 6b show 100％ larvicidal activity against Mythimna separate Walker at the test concentration of 100 mg/L.
基金This project was supported by the National Natural Science Foundation of Chinathe Natural Science Foundation of Tianjin.
文摘A variety of novel N-t-butyl-N'-aminocarbonyl-N-(substitute)Benzoylhydrazines containing α-aminoalkylphosphonate groups were synthesized by the addition of N-t-butyl-N- (substituted)benzoylhydrazines to α-isocyanatoalkylphosphonates. which were synthesized by the reaction of α-aminoalkylphosphonates with triphosgene in good yields. The structures of products including by-products were confirmed by 1H NMR, 31P NMR. IR, mass spectroscopy- and elemental analysis.
基金funded in part by the NNSFC(No.20872071)the NSF of Tianjin(No.10JCZDJC17500)+3 种基金the National Key Project for Basic Research(No.2010CB126105)National Key Technology Research and Development Program(Nos.2011BAE06B02 and 2011BAE06B05)the Foundation of Achievements Transformation and Application of Tianjin Agricultural Science and Technology(No.201002250)Tianjin Key Technology Research and Development Program(No.11ZCGYNC00100)
文摘A series of novel N-tert-butyl-N＇-acyl-5-methyl-1,2,3-thiadiazole-4-carbohydrazides were designed and synthesized. Their structures were characterized by melting points, ^1H NMR, IR, ESI-MS, and elemental analysis. The bioassay tests indicated that compound 7o exhibited excellent direct anti-TMV activity and induction activity in vivo at 50μg/mL, which was better than that of Ninamycin and tiadinial. Our studies indicated that 1,2,3-thiadiazole was an active substructure for novel pesticide development.
