The title complex Co（DMSO）2（H2O）2（SCN）2 has been prepared and structurally characterized. It crystallizes in monoclinic, space group P21/n with a= 5.1981（9）, b = 11.944（2）, c = 12.646（2） A,β = 98.686（2）...The title complex Co（DMSO）2（H2O）2（SCN）2 has been prepared and structurally characterized. It crystallizes in monoclinic, space group P21/n with a= 5.1981（9）, b = 11.944（2）, c = 12.646（2） A,β = 98.686（2）°, V = 776.2（2） A^3, C6H16CoN2O4S4, Mr = 367.38, Z = 2, De = 1.572 g/cm^3, F（000） = 378 and μ（MoKa） = 1.646 mm^-1. The structure was refined to R= 0.0232 and wR = 0.0645 for 1241 observed reflections with I 〉 2σ（I）. In the title complex, each Co（II） atom is octahedrally coordinated by four O atoms from two DMSO ligands and two water molecules as well as two N atoms from SCN^- ions. The title molecules are connected to each other through intermolecular hydrogen bonds to form a 1-D structure extended by eight-membered Co2O4H2 rings.展开更多
The brown metallic luster La-Ni alloy powders were prepared by potentiostatic electrolysis technique in dimethylsulfoxide solution at room temperature. The atomic rate of La and Ni in alloy powders are 11∶1 and 10∶1...The brown metallic luster La-Ni alloy powders were prepared by potentiostatic electrolysis technique in dimethylsulfoxide solution at room temperature. The atomic rate of La and Ni in alloy powders are 11∶1 and 10∶1. The size of metal grains is about 0.1 to 100 μm. It shows that the micrometer powders of rare earth alloys can be obtained by controlling electrodeposition conditions. The peak potentials of -2.81 and 1.75 V are attributed to reduction of La 3+ and Ni 3+ ions, respectively. The peak potentials at -2.20 and -0.168 V are the oxidation peaks of lanthanum and nickel, respectively. When potential is more negative than -1.74 V, La(Ⅲ) and Ni(Ⅱ) will codeposit. Increasing cyclic times, the value of peak current is decreasing, and the reduction peak of La(Ⅲ) was finally disappeared.展开更多
Seasonal and spatial distributions of dissolved and particulate dimethylsulfoxide(DMSOd,DMSOp)were measured in the East China Sea and the Yellow Sea during March–April 2011 and October–November 2011.The concentratio...Seasonal and spatial distributions of dissolved and particulate dimethylsulfoxide(DMSOd,DMSOp)were measured in the East China Sea and the Yellow Sea during March–April 2011 and October–November 2011.The concentrations of DMSOd and DMSOp in the surface water were 20.6(5.13–73.8)and 8.90(3.75–29.6)nmol/L in spring,and 13.4(4.17–42.7)and 8.18(3.44–22.6)nmol/L in autumn,respectively.Both DMSOd and DMSOp concentrations revealed similar seasonal changes with higher values occurring in spring,mainly because of the higher phytoplankton biomass observed in spring.Moreover,the ratios of DMSOp/chlorophyll a also exhibited an apparent seasonal change with higher values in autumn(35.7 mmol/g)and lower values in spring(23.4 mmol/g),thereby corresponding with the seasonal variation in the proportion of DMSO producers in the phytoplankton community between spring and autumn.In addition,DMSOd and DMSOp concentrations in the surface seawater revealed obvious diurnal variations with the maxima appearing in the afternoon.展开更多
Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a signifi...Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic effect.Therefore,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was explored.Methods:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood glucose.Triglyceride,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were observed.The 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal flora.Based on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was analyzed.Results:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control group.And SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric acid.Conclusion:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in rats.SDP against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.展开更多
基金This work was supported by the National Natural Science Foundation of China (No. 50572040)
文摘The title complex Co（DMSO）2（H2O）2（SCN）2 has been prepared and structurally characterized. It crystallizes in monoclinic, space group P21/n with a= 5.1981（9）, b = 11.944（2）, c = 12.646（2） A,β = 98.686（2）°, V = 776.2（2） A^3, C6H16CoN2O4S4, Mr = 367.38, Z = 2, De = 1.572 g/cm^3, F（000） = 378 and μ（MoKa） = 1.646 mm^-1. The structure was refined to R= 0.0232 and wR = 0.0645 for 1241 observed reflections with I 〉 2σ（I）. In the title complex, each Co（II） atom is octahedrally coordinated by four O atoms from two DMSO ligands and two water molecules as well as two N atoms from SCN^- ions. The title molecules are connected to each other through intermolecular hydrogen bonds to form a 1-D structure extended by eight-membered Co2O4H2 rings.
文摘The brown metallic luster La-Ni alloy powders were prepared by potentiostatic electrolysis technique in dimethylsulfoxide solution at room temperature. The atomic rate of La and Ni in alloy powders are 11∶1 and 10∶1. The size of metal grains is about 0.1 to 100 μm. It shows that the micrometer powders of rare earth alloys can be obtained by controlling electrodeposition conditions. The peak potentials of -2.81 and 1.75 V are attributed to reduction of La 3+ and Ni 3+ ions, respectively. The peak potentials at -2.20 and -0.168 V are the oxidation peaks of lanthanum and nickel, respectively. When potential is more negative than -1.74 V, La(Ⅲ) and Ni(Ⅱ) will codeposit. Increasing cyclic times, the value of peak current is decreasing, and the reduction peak of La(Ⅲ) was finally disappeared.
基金The National Natural Science Foundation of China under contract Nos 41576073,41306069 and 41320104008the National Key Research and Development Program of China under contract No.2016YFA0601301
文摘Seasonal and spatial distributions of dissolved and particulate dimethylsulfoxide(DMSOd,DMSOp)were measured in the East China Sea and the Yellow Sea during March–April 2011 and October–November 2011.The concentrations of DMSOd and DMSOp in the surface water were 20.6(5.13–73.8)and 8.90(3.75–29.6)nmol/L in spring,and 13.4(4.17–42.7)and 8.18(3.44–22.6)nmol/L in autumn,respectively.Both DMSOd and DMSOp concentrations revealed similar seasonal changes with higher values occurring in spring,mainly because of the higher phytoplankton biomass observed in spring.Moreover,the ratios of DMSOp/chlorophyll a also exhibited an apparent seasonal change with higher values in autumn(35.7 mmol/g)and lower values in spring(23.4 mmol/g),thereby corresponding with the seasonal variation in the proportion of DMSO producers in the phytoplankton community between spring and autumn.In addition,DMSOd and DMSOp concentrations in the surface seawater revealed obvious diurnal variations with the maxima appearing in the afternoon.
基金supported by the Fundamental Research Foundation of the National Natural Science Foundation of China(No.82174111)the State Administration of Traditional Chinese Medicine and the Sci-Tech Innovation Talent System Construction Program of Shaanxi University of Chinese Medicine(No.2023-CXTD-05).
文摘Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic effect.Therefore,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was explored.Methods:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood glucose.Triglyceride,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were observed.The 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal flora.Based on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was analyzed.Results:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control group.And SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric acid.Conclusion:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in rats.SDP against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.
