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肠道细胞中铁、锌吸收与DMT-1相互关系的研究进展
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作者 金融 赵念 +1 位作者 陈莎莎 王恬 《家畜生态学报》 2006年第6期206-209,共4页
铁、锌是动物重要的微量元素,对维持机体正常代谢起着关键的作用,其过量和缺乏都会对机体产生极大危害。本文综述了铁和锌吸收的相互作用、铁和锌吸收与DMT-1的相互关系以及影响铁锌吸收的其它因素,提出肠道细胞对铁、锌吸收的相互竞争... 铁、锌是动物重要的微量元素,对维持机体正常代谢起着关键的作用,其过量和缺乏都会对机体产生极大危害。本文综述了铁和锌吸收的相互作用、铁和锌吸收与DMT-1的相互关系以及影响铁锌吸收的其它因素,提出肠道细胞对铁、锌吸收的相互竞争,而这种竞争并非发生在DMT-1这一位点。 展开更多
关键词 dmt-1
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Water storage variations of the Yangtze,Yellow,and Zhujiang river basins derived from the DEOS Mass Transport (DMT-1) model 被引量:1
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作者 ZHAO QiLe LIU XiangLin +4 位作者 Pavel DITMAR Christian SIEMES Elena REVTOVA Hassan HASHEMI-FARAHANI Roland KLEES 《Science China Earth Sciences》 SCIE EI CAS 2011年第5期667-677,共11页
In general, China is short of water resources and some regions even experience a shortage of daily water supply. This could threaten the stability and economic development of the nation. A study on the water storage v... In general, China is short of water resources and some regions even experience a shortage of daily water supply. This could threaten the stability and economic development of the nation. A study on the water storage variations is especially important for the water management and storage prediction in three largest river basins of China, namely, Yangtze, Yellow, and Zhujiang, where the most dense population and leading economic regions are located. The satellite gravity mission GRACE (Gravity Recovery and Climate Experiment) provides an opportunity to macroseopically identify water (or mass) variations in the Earth's system with a spatial resolution of 300-400 km and a temporal resolution of about one month. We use the first release of the DEOS (Delft Institute of Earth Observation and Space Systems) Mass Transport (DMT-1) model based on GRACE data to analyze water storage changes in the three river basins. The DMT-1 model consists of monthly solutions, which are computed using an innovative methodology. The methodology includes, in particular, the application of a statistically optimal Wiener-type filter based on full varianee-covariance matrices of noise and signal. This results in particularly sharp mass variation maps. Taking one monthly solution as an example, we compare the results derived from the DMT-1 model with ones produced with the standard post-processing scheme based on a combination of the de-striping and Gaussian filtering. The comparison shows that the DMT-1 model outperforms the other models and is suitable for the analysis of the mass changes in river basins. A subset of the DMT-1 solutions in the interval between February 2003 and May 2008 is used to estimate the secular trends and seasonal variations for the three river basins. The estimated trends show that the water storage of the Yellow River basin does not have significant changes, while the Zhujiang and Yangtze river basins have a large and statistically significant water storage increase. The estimation of seasonal variations demonstrates that the water storage variations in Yangtze and Zhujiang river basins are almost in the same phase. The amplitude of variations in the Zhujiang River basin is larger than that in Yangtze. No clear annual variations are observed in the Yellow River basin. The observed water storage variations generally coincide with the observations and conclusions presented in the hydrological reports of the Chinese Ministry of Water Resources 展开更多
关键词 GRACE dmt-1 water storage variation equivalent water layer thickness Yangtze-Yeilow-Zhujiang river basins secular and seasonal variation
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玫瑰茄水提物抗贫血作用的研究 被引量:2
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作者 曾荣 方舒婷 +3 位作者 赵文俊 林淇淇 何锡媛 王嫣如 《现代食品科技》 EI CAS 北大核心 2019年第11期16-24,共9页
初步探究玫瑰茄水提物的抗贫血作用机制。建立IDA大鼠模型,随机分成4组,对IDA大鼠灌胃低、中、高剂量的玫瑰茄水提物。30d后,解剖大鼠,取十二指肠和肝脏。利用Q-PCR和Westernblot技术分别检测试验大鼠十二指肠中二价金属转运体(DMT-1)... 初步探究玫瑰茄水提物的抗贫血作用机制。建立IDA大鼠模型,随机分成4组,对IDA大鼠灌胃低、中、高剂量的玫瑰茄水提物。30d后,解剖大鼠,取十二指肠和肝脏。利用Q-PCR和Westernblot技术分别检测试验大鼠十二指肠中二价金属转运体(DMT-1)、膜铁转运蛋白(FPN-1)、膜铁转运辅助蛋白(Hp)及其mRNA的表达量,肝脏铁调素(Hepcidin)及其mRNA的表达水平。结果表明,与低铁对照组比较,玫瑰茄水提物低、中剂量组对DMT-1、FPN-1、Hp表达量的下调幅度不超过9%,mRNA的表达水平则超过50%,低、中剂量均对Hp mRNA无显著性差异;高剂量组对DMT-1、FPN-1、Hp及其mRNA表达量的下调程度不一。低剂量组Hepcidin-25的表达量是低铁对照组的1.61倍;高剂量组的表达量则下调了65.79%;各剂量组均抑制了相关mRNA的表达。因此,玫瑰茄水提物通过提供有效成分促进机体铁的吸收,从而影响IDA大鼠的DMT-1、FPN-1、Hp、Hepcidin-25及其mRNA的表达,维持机体铁稳态。 展开更多
关键词 玫瑰茄水提物 二价金属转运体 膜铁转运蛋白 膜铁转运辅助蛋白 铁调素
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