A new glycoside, cervicoside, was isolated from the soft coral Sinularia cervicornis Tix Dur ., collected from the bay of Sanya, Hainan Island. Its chemical structure was determined by spectroscopic methods as hexadec...A new glycoside, cervicoside, was isolated from the soft coral Sinularia cervicornis Tix Dur ., collected from the bay of Sanya, Hainan Island. Its chemical structure was determined by spectroscopic methods as hexadecanyl 1 O β D arabinopyranosyloxy (1→4) [ β D arabinopyranosyloxy(1→4)] β D arabinopyranoside. Cervicoside(1) exhibited cytotoxicity against human SKMG 4, Hep G2 and CNE2 cell in vitro.展开更多
In accordance with the timely weather report and routine meteorological resources of the meteorological observatory of Liaoning Province from 1979 to 2009,durative fog occurred in Liaoning and their characteristics we...In accordance with the timely weather report and routine meteorological resources of the meteorological observatory of Liaoning Province from 1979 to 2009,durative fog occurred in Liaoning and their characteristics were counted and analyzed in this paper.The report showed that the continuous hazy days occurred three times in 30 years and they had large chances to take place in winter.After the heavy precipitation in the North China and Northeast China,temperature in every place turned up again.If under such circumstances,expansion and temperature inversion happened in the 925 hPa and the wind speed was slower than 4 to 8 m/s in the 1 000 hPa,continuous hazy days happened.展开更多
By means of Tersoff and Morse potentials, a three-dimensional molecular dynamics simulation is performed to study atomic force microscopy cutting on silicon monocrystal surface. The interatomic forces between the work...By means of Tersoff and Morse potentials, a three-dimensional molecular dynamics simulation is performed to study atomic force microscopy cutting on silicon monocrystal surface. The interatomic forces between the workpiece and the pin tool and the atoms of workpiece themselves are calculated. A screw dislocation is introduced into workpiece Si. It is found that motion of dislocations does not occur during the atomic force microscopy cutting processing. Simulation results show that the shear stress acting on dislocation is far below the yield strength of Si.展开更多
In the study of double pulse ablation of materials (silicon and copper), a dropdown of double pulse to single pulse fluorescence signal enhancement at low fluences is observed. The dropdown is analysed with a simple...In the study of double pulse ablation of materials (silicon and copper), a dropdown of double pulse to single pulse fluorescence signal enhancement at low fluences is observed. The dropdown is analysed with a simple theoretical one-dimensional heat diffusion model and verified by fluorescence time constants change as a function of fluence. The dropdown is explained as a result of liquid-solid mixture layer at the liquid and solid boundary. The effect of the layer becomes important at low fluences.展开更多
Previous literature shows that scholars differ considerably on what zai and-zhe indicate.By making use of an oral speech corpus,we analyzed and tested the data with regard to the functions of "zai" and "...Previous literature shows that scholars differ considerably on what zai and-zhe indicate.By making use of an oral speech corpus,we analyzed and tested the data with regard to the functions of "zai" and "-zhe" and found that zai indicates the action is in progress,and it is narrative,while-zhe expresses the ongoing state of an action and is descriptive;-zhe can be used after the first verb in a serial verbal con struction to indicate the accompanying action,while zai does not have this function;in complex sentences,the zai clause is temporal in na ture while-zhe clause is treated as a manner adverbial.展开更多
Whole rock 40Ar/39Ar age dating has been conducted on a basalt sample from Dur’ngoi ophiolite, Qinghai Province, which was reported to be the northernmost pa-leo-tethyan oceanic basin in Tibet. A high temperature pla...Whole rock 40Ar/39Ar age dating has been conducted on a basalt sample from Dur’ngoi ophiolite, Qinghai Province, which was reported to be the northernmost pa-leo-tethyan oceanic basin in Tibet. A high temperature pla-teau age (345.3±7.9 Ma) with an isochorn age (336.6±7.1 Ma) has been obtained, representing the eruption time of oceanic crust Considering related geological settings, the new age provides constraints on the northernmost pa-leo-tethyan suture zone in Tibet and the tectonic evolution of Paleo-tethys in Northeast Tibet and adjacent areas.展开更多
The A'nyemaqen (阿尼玛卿) ophiolite belt along the southern margin of the East Kunlun (昆仑) Mountains marks the suture formed by the closure of paleo-Tethys. The Dur'ngoi ophiolite in the eastern part of this b...The A'nyemaqen (阿尼玛卿) ophiolite belt along the southern margin of the East Kunlun (昆仑) Mountains marks the suture formed by the closure of paleo-Tethys. The Dur'ngoi ophiolite in the eastern part of this belt consists of meta-peridotite, mafic-ultramafic cumulates, sheeted dikes and basaltic lavas. The meta-peridotites consist of dunite, harzburgite, lherzolite, feldspar-bearing lherzolite and garnet-bearing lherzolite and contain residual spinel with Cr# [100×Cr/(Cr+Al)] ranging from 30 to 57 and Mg# [100×Mg/(Mg+Fe2+)] ranging from 50 to 75, indicating an Al- and Mg-rich series. The meta-peridotites have a relatively narrow range of composition with Mg# of 89.2-92.6, Al2O3 contents of (1-4) wt.% and slightly depleted chondrite normalized REE patterns, indicating that they represent relict mantle material that has undergone intermediate to low degrees of partial melting. Garnets in the lherzolite are andradite, enriched in Ca and Fe and depleted in Mg and AI (And=95-97, Pyr=0.3-5, Gro=0-3), indicating a metamorphic origin. The cumulate rocks mainly consist of dunite, wehrlite, pyroxenite and gabbro. A well-layered gabbro-pyroxenite complex is defined by modal variations in plagioclase and pyroxene. Blocks of garnet-pyroxenite or rodingite are locally present in the meta-peridotites. Garnets in the cumulate rocks are grossular (Gro=69-90, And=9-19, Br=l-12), also metamorphic origin. The diabase dikes are moderately depleted in LREE [(La/Sm)N=0.5-0.8] and HREE resulting in slightly convex chondrite-normalized patterns with slightly positive Eu anomalies (δEu=1.1-1.3). The basaltic lavas have REE patterns similar to those of MORB with (La/Sm)N ratios of 0.5-1 and small negative Eu anomalies. They appear to have been derived from a depleted mantle source and to have undergone little or no differentiation during crystallization. SHRIMP U-Pb dating of zircons from the basalts yields 286pb/238U ages of 276-319 Ma (average 308.0±4.9 Ma). The Dur'ngoi ophiolite is interpreted as a dismembered fragment of paleo-oceanic crust emplaced during closure of the paleo-Tethyan Ocean basin. Three other suites of oceanic lavas are recognized in the area: island arc volcanic (IAV) rocks, possible back arc basin (BAB) basalts and possible post-collisional volcanic (PCV) and plutonic rocks. The distribution of these rocks suggests north-directed subduction. Opening of the A'nyemaqen oceanic basin started at least as early as Late Carboniferous (308 Ma) and the basin probably closed during the Early Triassic. The IAV formed in Late Permian (260 Ma), the BAB in Early-Middle Triassic, and the PCV in Late Triassic. Several large scale, ductile, sinistral strike-slip fault zones, extending hundreds to thousands kilometers, formed along or north of the suture during the Early-Late Triassic, e.g., they are the south margin fault zone of East Kunlun (200-220 Ma), the Altyn Tagh fault (220-230 Ma), and the North Qaidam fault zone (240-250 Ma). These strike-slip faults were probably generated by oblique subduction and closure of the paleo-Tethyan Ocean basin, possibly during exhumation of the subducted plate or uplift of the overriding plate, coincident with post-collisional magmatism.展开更多
药物利用评价(Drug use review,DUR)是指在一定范围内按规定标准对药物的使用进行药学、医疗和管理的评价。药物利用评估(Drug use evaluation,DUE)是系统的、连续的、有组织的、被医院权威部门授权的以保证药品使用正确、安全、有...药物利用评价(Drug use review,DUR)是指在一定范围内按规定标准对药物的使用进行药学、医疗和管理的评价。药物利用评估(Drug use evaluation,DUE)是系统的、连续的、有组织的、被医院权威部门授权的以保证药品使用正确、安全、有效的一种质量保证程序。本文通过采用DUR和DUE方法对我院心内科高血压患者的用药情况进行分析。报告如下。展开更多
目的探讨头孢曲松钠联合苄星青霉素对不同孕周的妊娠期梅毒孕妇免疫功能及母婴结局的影响。方法选取2016年6月至2019年6月衡水市第三人民医院妇产科收治的妊娠期梅毒病人152例,均给予头孢曲松钠联合苄星青霉素治疗,按首次治疗时所在孕...目的探讨头孢曲松钠联合苄星青霉素对不同孕周的妊娠期梅毒孕妇免疫功能及母婴结局的影响。方法选取2016年6月至2019年6月衡水市第三人民医院妇产科收治的妊娠期梅毒病人152例,均给予头孢曲松钠联合苄星青霉素治疗,按首次治疗时所在孕周分为A组(n=52,孕周<13周)、B组(n=61,孕周13~27周)、C组(n=39,孕周>27周),比较三组免疫功能、母婴结局、氧化应激、母婴甲苯胺红不加热血清试验(TRUST)阴性率、滴度情况。结果治疗后三组CD3+(62.85±3.89、57.72±4.03、57.13±4.11)、CD4+/CD8+(1.97±0.44、1.58±0.41、1.46±0.38)均高于治疗前(51.07±4.54、51.35±4.06、50.73±4.45、1.19±0.38、1.14±0.36、1.12±0.34)(P<0.05),CD8+(22.32±6.68、26.68±6.05、28.23±5.74)均低于治疗前(33.01±5.15、32.76±5.34、33.12±4.95)(P<0.05),且治疗后A组CD3+、CD4+/CD8+均高于B组、C组(P<0.05),CD8+均低于B组、C组(P<0.05)。A组孕妇分娩孕周均晚于B组、C组(P<0.05),足月分娩率高于B组、C组(P<0.05),不良结局总发生率低于B组、C组(P<0.05),新生儿1 min阿氏(Apgar)评分均大于B组、C组(P<0.05),5 min Apgar评分均大于B组、C组(P<0.05),新生儿窒息发生率与NCS发生率均低于B组、C组(P<0.05)。治疗后三组晚期氧化蛋白产物(AOPP)、丙二醛均低于治疗前(P<0.05),超氧化物歧化酶(SOD)均高于治疗前(P<0.05),且治疗后A组AOPP、丙二醛均低于B组、C组(P<0.05),SOD均高于B组、C组(P<0.05)。A组新生儿TRUST阴性率高于B组、C组(均P<0.017)。结论对妊娠期梅毒病人来说,孕早期(孕周<13周)给予头孢曲松钠联合苄星青霉素治疗更利于增强病人免疫功能,改善母婴结局,减轻病人氧化应激水平,提高新生儿TRUST阴性率。展开更多
文摘A new glycoside, cervicoside, was isolated from the soft coral Sinularia cervicornis Tix Dur ., collected from the bay of Sanya, Hainan Island. Its chemical structure was determined by spectroscopic methods as hexadecanyl 1 O β D arabinopyranosyloxy (1→4) [ β D arabinopyranosyloxy(1→4)] β D arabinopyranoside. Cervicoside(1) exhibited cytotoxicity against human SKMG 4, Hep G2 and CNE2 cell in vitro.
文摘In accordance with the timely weather report and routine meteorological resources of the meteorological observatory of Liaoning Province from 1979 to 2009,durative fog occurred in Liaoning and their characteristics were counted and analyzed in this paper.The report showed that the continuous hazy days occurred three times in 30 years and they had large chances to take place in winter.After the heavy precipitation in the North China and Northeast China,temperature in every place turned up again.If under such circumstances,expansion and temperature inversion happened in the 925 hPa and the wind speed was slower than 4 to 8 m/s in the 1 000 hPa,continuous hazy days happened.
基金Supported by the National Natural Science Foundation of China under Grant No 10372107 and 10721202, and the Knowledge Innovation Project of Chinese Academy of Sciences under Grant No KJCX2-YW-M04.
文摘By means of Tersoff and Morse potentials, a three-dimensional molecular dynamics simulation is performed to study atomic force microscopy cutting on silicon monocrystal surface. The interatomic forces between the workpiece and the pin tool and the atoms of workpiece themselves are calculated. A screw dislocation is introduced into workpiece Si. It is found that motion of dislocations does not occur during the atomic force microscopy cutting processing. Simulation results show that the shear stress acting on dislocation is far below the yield strength of Si.
基金Supported by the National Natural Science Foundation of China under Grant No 10404008, the National Science Foundation from United States under Grants Nos PHY-0200812, CHE-0120997 and CHE-0640306, and the Motorola Physical Realization Research Center in Schaumburg, IL.
文摘In the study of double pulse ablation of materials (silicon and copper), a dropdown of double pulse to single pulse fluorescence signal enhancement at low fluences is observed. The dropdown is analysed with a simple theoretical one-dimensional heat diffusion model and verified by fluorescence time constants change as a function of fluence. The dropdown is explained as a result of liquid-solid mixture layer at the liquid and solid boundary. The effect of the layer becomes important at low fluences.
文摘Previous literature shows that scholars differ considerably on what zai and-zhe indicate.By making use of an oral speech corpus,we analyzed and tested the data with regard to the functions of "zai" and "-zhe" and found that zai indicates the action is in progress,and it is narrative,while-zhe expresses the ongoing state of an action and is descriptive;-zhe can be used after the first verb in a serial verbal con struction to indicate the accompanying action,while zai does not have this function;in complex sentences,the zai clause is temporal in na ture while-zhe clause is treated as a manner adverbial.
基金This work was supported by the NationalNatural Science Foundation of China (Grant No. 49732080) the State Major Basic Research Development Program (Grant No. G1999075508) and the Natural Science Foundation of Northwest University (Grant No. 99NW28)
文摘Whole rock 40Ar/39Ar age dating has been conducted on a basalt sample from Dur’ngoi ophiolite, Qinghai Province, which was reported to be the northernmost pa-leo-tethyan oceanic basin in Tibet. A high temperature pla-teau age (345.3±7.9 Ma) with an isochorn age (336.6±7.1 Ma) has been obtained, representing the eruption time of oceanic crust Considering related geological settings, the new age provides constraints on the northernmost pa-leo-tethyan suture zone in Tibet and the tectonic evolution of Paleo-tethys in Northeast Tibet and adjacent areas.
基金supported by China Geological Survey (Nos. 1212010918013 and 1212010610105)
文摘The A'nyemaqen (阿尼玛卿) ophiolite belt along the southern margin of the East Kunlun (昆仑) Mountains marks the suture formed by the closure of paleo-Tethys. The Dur'ngoi ophiolite in the eastern part of this belt consists of meta-peridotite, mafic-ultramafic cumulates, sheeted dikes and basaltic lavas. The meta-peridotites consist of dunite, harzburgite, lherzolite, feldspar-bearing lherzolite and garnet-bearing lherzolite and contain residual spinel with Cr# [100×Cr/(Cr+Al)] ranging from 30 to 57 and Mg# [100×Mg/(Mg+Fe2+)] ranging from 50 to 75, indicating an Al- and Mg-rich series. The meta-peridotites have a relatively narrow range of composition with Mg# of 89.2-92.6, Al2O3 contents of (1-4) wt.% and slightly depleted chondrite normalized REE patterns, indicating that they represent relict mantle material that has undergone intermediate to low degrees of partial melting. Garnets in the lherzolite are andradite, enriched in Ca and Fe and depleted in Mg and AI (And=95-97, Pyr=0.3-5, Gro=0-3), indicating a metamorphic origin. The cumulate rocks mainly consist of dunite, wehrlite, pyroxenite and gabbro. A well-layered gabbro-pyroxenite complex is defined by modal variations in plagioclase and pyroxene. Blocks of garnet-pyroxenite or rodingite are locally present in the meta-peridotites. Garnets in the cumulate rocks are grossular (Gro=69-90, And=9-19, Br=l-12), also metamorphic origin. The diabase dikes are moderately depleted in LREE [(La/Sm)N=0.5-0.8] and HREE resulting in slightly convex chondrite-normalized patterns with slightly positive Eu anomalies (δEu=1.1-1.3). The basaltic lavas have REE patterns similar to those of MORB with (La/Sm)N ratios of 0.5-1 and small negative Eu anomalies. They appear to have been derived from a depleted mantle source and to have undergone little or no differentiation during crystallization. SHRIMP U-Pb dating of zircons from the basalts yields 286pb/238U ages of 276-319 Ma (average 308.0±4.9 Ma). The Dur'ngoi ophiolite is interpreted as a dismembered fragment of paleo-oceanic crust emplaced during closure of the paleo-Tethyan Ocean basin. Three other suites of oceanic lavas are recognized in the area: island arc volcanic (IAV) rocks, possible back arc basin (BAB) basalts and possible post-collisional volcanic (PCV) and plutonic rocks. The distribution of these rocks suggests north-directed subduction. Opening of the A'nyemaqen oceanic basin started at least as early as Late Carboniferous (308 Ma) and the basin probably closed during the Early Triassic. The IAV formed in Late Permian (260 Ma), the BAB in Early-Middle Triassic, and the PCV in Late Triassic. Several large scale, ductile, sinistral strike-slip fault zones, extending hundreds to thousands kilometers, formed along or north of the suture during the Early-Late Triassic, e.g., they are the south margin fault zone of East Kunlun (200-220 Ma), the Altyn Tagh fault (220-230 Ma), and the North Qaidam fault zone (240-250 Ma). These strike-slip faults were probably generated by oblique subduction and closure of the paleo-Tethyan Ocean basin, possibly during exhumation of the subducted plate or uplift of the overriding plate, coincident with post-collisional magmatism.
文摘药物利用评价(Drug use review,DUR)是指在一定范围内按规定标准对药物的使用进行药学、医疗和管理的评价。药物利用评估(Drug use evaluation,DUE)是系统的、连续的、有组织的、被医院权威部门授权的以保证药品使用正确、安全、有效的一种质量保证程序。本文通过采用DUR和DUE方法对我院心内科高血压患者的用药情况进行分析。报告如下。
文摘目的探讨头孢曲松钠联合苄星青霉素对不同孕周的妊娠期梅毒孕妇免疫功能及母婴结局的影响。方法选取2016年6月至2019年6月衡水市第三人民医院妇产科收治的妊娠期梅毒病人152例,均给予头孢曲松钠联合苄星青霉素治疗,按首次治疗时所在孕周分为A组(n=52,孕周<13周)、B组(n=61,孕周13~27周)、C组(n=39,孕周>27周),比较三组免疫功能、母婴结局、氧化应激、母婴甲苯胺红不加热血清试验(TRUST)阴性率、滴度情况。结果治疗后三组CD3+(62.85±3.89、57.72±4.03、57.13±4.11)、CD4+/CD8+(1.97±0.44、1.58±0.41、1.46±0.38)均高于治疗前(51.07±4.54、51.35±4.06、50.73±4.45、1.19±0.38、1.14±0.36、1.12±0.34)(P<0.05),CD8+(22.32±6.68、26.68±6.05、28.23±5.74)均低于治疗前(33.01±5.15、32.76±5.34、33.12±4.95)(P<0.05),且治疗后A组CD3+、CD4+/CD8+均高于B组、C组(P<0.05),CD8+均低于B组、C组(P<0.05)。A组孕妇分娩孕周均晚于B组、C组(P<0.05),足月分娩率高于B组、C组(P<0.05),不良结局总发生率低于B组、C组(P<0.05),新生儿1 min阿氏(Apgar)评分均大于B组、C组(P<0.05),5 min Apgar评分均大于B组、C组(P<0.05),新生儿窒息发生率与NCS发生率均低于B组、C组(P<0.05)。治疗后三组晚期氧化蛋白产物(AOPP)、丙二醛均低于治疗前(P<0.05),超氧化物歧化酶(SOD)均高于治疗前(P<0.05),且治疗后A组AOPP、丙二醛均低于B组、C组(P<0.05),SOD均高于B组、C组(P<0.05)。A组新生儿TRUST阴性率高于B组、C组(均P<0.017)。结论对妊娠期梅毒病人来说,孕早期(孕周<13周)给予头孢曲松钠联合苄星青霉素治疗更利于增强病人免疫功能,改善母婴结局,减轻病人氧化应激水平,提高新生儿TRUST阴性率。