The genetic polymorphism across 17 Y-STR loci in a population of Han Chinese in Lanzhou was investigated.Haplotypes and allele frequencies for the 17 Y-chromosomal STRs loci DYS456,DYS389I,DYS390,DYS389Ⅱ,DYS458,DYS19...The genetic polymorphism across 17 Y-STR loci in a population of Han Chinese in Lanzhou was investigated.Haplotypes and allele frequencies for the 17 Y-chromosomal STRs loci DYS456,DYS389I,DYS390,DYS389Ⅱ,DYS458,DYS19,DYS385a/b,DYS393,DYS391,DYS439,DYS635,DYS392,Y GATA H4,DYS437,DYS438 and DYS448 were determined in 500 healthy unrelated autochthonous males from Lanzhou.The results showed that no shared haplotypes were observed.Gene diversity values ranged from 0.3987(DYS391)to 0.9740(DYS385a,b).It was concluded that these loci will be very useful for human identification in forensic cases and paternity tests within the Han Chinese population inhabiting Lanzhou.展开更多
文摘以中国甘肃的3个特有少数民族,天水汉族、天水回族、临夏回族6人群为研究对象,采用 RCR 技术及变性聚丙烯酰胺凝胶电泳法,分析了高变染色体特异的微卫星 DYS19的等位基因分布规律,共检出7种等位基因.甘肃3个特有少数民族 DYS19的等位基因频率存在显著性差异(P<0.05).通过 PCR 方法调查了 Alu 元件插入基因座 DYS287的多态性.结果显示,除保安族没有发现 Alu 插入外,其他人群均发现 Alu 插入,其中临夏回族表现了较高的插入频率(12.9%).MDS 分析表明:裕固族和汉族的遗传关系比较接近,6人群遗传距离和空间距离没有明显的相关性.
基金supported by grants from the Science Technology Foundation of Lanzhou(No.2012-1-22)Youth Science and Technology Foundation of Gansu(No.1208RJYA073)National Natural Science Foundation of China(No.81302622)
文摘The genetic polymorphism across 17 Y-STR loci in a population of Han Chinese in Lanzhou was investigated.Haplotypes and allele frequencies for the 17 Y-chromosomal STRs loci DYS456,DYS389I,DYS390,DYS389Ⅱ,DYS458,DYS19,DYS385a/b,DYS393,DYS391,DYS439,DYS635,DYS392,Y GATA H4,DYS437,DYS438 and DYS448 were determined in 500 healthy unrelated autochthonous males from Lanzhou.The results showed that no shared haplotypes were observed.Gene diversity values ranged from 0.3987(DYS391)to 0.9740(DYS385a,b).It was concluded that these loci will be very useful for human identification in forensic cases and paternity tests within the Han Chinese population inhabiting Lanzhou.