In the present study, 36 cases of irritable bowel syndrome were treated by acupuncturing some acupoints selected according to differentiation of syndromes of traditional Chinese medicine.After 10 - 30 sessions of trea...In the present study, 36 cases of irritable bowel syndrome were treated by acupuncturing some acupoints selected according to differentiation of syndromes of traditional Chinese medicine.After 10 - 30 sessions of treatment, 35 cases were cured and the rest one case had improvement, with the effective rate being 100 %.展开更多
以La_2O_3和Ta_2O_5为原材料,采用固相反应法制备了La_2La Ta O_7粉体。用X射线衍射技术、扫描电子显微镜、EDS电子能谱分析了粉体的相结构,显微形貌和元素组成。用激光颗粒度仪和比表面积分析仪分析了粉体的颗粒度及表面积,用可见光照...以La_2O_3和Ta_2O_5为原材料,采用固相反应法制备了La_2La Ta O_7粉体。用X射线衍射技术、扫描电子显微镜、EDS电子能谱分析了粉体的相结构,显微形貌和元素组成。用激光颗粒度仪和比表面积分析仪分析了粉体的颗粒度及表面积,用可见光照射下亚甲基蓝的降解率分析了该粉体的光催化活性。结果表明,本文成功合成了纯净具有单一氟铝镁钠石结构的La_2La Ta O_7粉体,粉体具有明显的团聚现象,其平均颗粒度约为24μm,比表面积仅为0.463 m^2/g。经过150 min照射后,该粉体对亚甲基蓝的降解率达到68%,其较低的降解率可能与其较低的比表面积有关。展开更多
AIM:To investigate the effect and mechanism of acupuncture at heterotopic acupoints on jejunal motility,particularly in pathological conditions.METHODS:Jejunal motility was assessed using a manometric balloon placed i...AIM:To investigate the effect and mechanism of acupuncture at heterotopic acupoints on jejunal motility,particularly in pathological conditions.METHODS:Jejunal motility was assessed using a manometric balloon placed in the jejunum approximately18-20 cm downstream from the pylorus and filled with approximately 0.1 m L warm water in anesthetized normal rats or rats with diarrhea or constipation.The heterotopic acupoints including LI11(Quchi),ST37(Shangjuxu),BL25(Dachangshu),and the homotopic acupoint ST25(Tianshu),and were stimulated for 60 s by rotating acupuncture needles right and left at a frequency of 2 Hz.To determine the type of afferent fibers mediating the regulation of jejunal motility by manual acupuncture,the ipsilateral sciatic A or C fibers of ST37 were inactivated by local application of the A-fiber selective demyelination agent cobra venom or the C fiber blocker capsaicin.Methoctramine,a selective M2 receptor antagonist,was injected intravenously to identify a specific role for M2 receptors in mediating the effect of acupuncture on jejunal motility.RESULTS:Acupuncture at heterotopic acupoints,such as LI11 and ST37,increased jejunal motility not only in normal rats,but also in rats with constipation or diarrhea.In normal rats,manual acupuncture at LI11 or ST37 enhanced jejunal pressure from 7.34±0.19 cmH2O to 7.93±0.20 cm H2O,an increase of 9.05%±0.82%(P<0.05),and from 6.95±0.14 cm H2O to 8.97±0.22cm H2O,a significant increase of 27.44%±1.96%(P<0.01),respectively.In constipated rats,manual acupuncture at LI11 or ST37 increased intrajejunal pressure from8.17±0.31 cm H2O to 9.86±0.36 cm H2O,an increase of 20.69%±2.10%(P<0.05),and from 8.82±0.28cm H2O to 10.83±0.28 cm H2O,an increase of 22.81%±1.46%(P<0.05),respectively.In rats with diarrhea,MA at LI11 or ST37 increased intrajejunal pressure from 11.95±0.35 cm H2O to 13.96±0.39 cm H2O,an increase of 16.82%±2.35%(P<0.05),and tended to increase intrajejunal pressure(from 12.42±0.38 cm H2O to 13.05±0.38 cm H2O,an increase of 5.07%±1.08%,P>0.05),respectively.In contrast,acupuncture ST25,a homotopic acupoint,decreased not only intrajejunal pressure,but also significantly decreased frequency in normal rats and rats with constipation or diarrhea.Following demyelination of Aδfibers,acupuncture at ST37again augmented intrajejunal pressure to 121.48%±3.06%of baseline.Following capsaicin application for24 h,acupuncture at ipsilateral ST37 increased intrajejunal pressure significantly to 106.63%±1.26%of basallevels when compared to measurements prior to capsaicin treatment(P<0.05).Acupuncture at LI11,ST37,or BL25 significantly rescued methoctramine-mediated inhibition of jejunal motility amplitude from 42.83%±1.65%to 53.43%±1.95%of baseline(P<0.05),from45.15%±2.22%to 70.51%±2.34%of baseline(P<0.01),and from 38.03%±2.34%to 70.12%±2.22%of baseline(P<0.01),respectively.CONCLUSION:Acupuncture at heterotopic acupoints increases the amplitude of jejunal motility in rats.C fibers and M2 receptors predominantly and partially mediate the regulation of jejunal motility by acupuncture,respectively.展开更多
Lumbar three point needling”, meaning puncturing Shenshu (BL 23), Dachangshu (BL 25) and Ciliao(BL 32) at the same time, is a commonly used acupuncture method in the treatment of lumbocrural diseases. Points suppleme...Lumbar three point needling”, meaning puncturing Shenshu (BL 23), Dachangshu (BL 25) and Ciliao(BL 32) at the same time, is a commonly used acupuncture method in the treatment of lumbocrural diseases. Points supplemented according to symptoms: Weizhong(BL 40) is supplemented for lumbar vertebra hypertrophy spondylitis; Weizhong (BL 40) and Kunlun(BL 60) supplemented for acute lumbar muscle sprain; Zhibian (BL 54), Huantiao (GB 30) and Ahshi points supplemented for nervi cluniam superior inflammation, and Sanyinjiao (SP 6) and Mingmen(GV 4) supplemented for impotence. Gauge 28 2 cun long needles are used. The needles are inserted perpendicularly into Shenshu(BL 23), Dachengshu(BL 25) and Ciliao(BL 32) to a depth of about 1.2～1.5 cun. Other supplementary points are needled and stimulated with routine manipulations, generally the reducing method is used for excess syndrome, and the reinforcing method applied to deficiency syndrome. The author, on the basis of many years of clinical practice, considers that “lumbar three point needling” is fairly effective in treating lumbosacral diseases.展开更多
目的:比较针刺天枢、大肠俞为主与口服西药马来酸曲美布汀治疗肠易激综合征的疗效差异。方法:将40例患者随机分针刺组和西药组,每组20例。针刺组针刺天枢、大肠俞为主,采用子午捣臼法,每天1次;西药组口服马来酸曲美布汀胶囊,每次2粒,每...目的:比较针刺天枢、大肠俞为主与口服西药马来酸曲美布汀治疗肠易激综合征的疗效差异。方法:将40例患者随机分针刺组和西药组,每组20例。针刺组针刺天枢、大肠俞为主,采用子午捣臼法,每天1次;西药组口服马来酸曲美布汀胶囊,每次2粒,每日3次,两组均治疗4周后评定疗效。结果:两组患者治疗后腹痛时间、腹痛频率、排便形状异常比率、排便通过异常比率、黏液便比率、排便时腹胀或腹痛积分均较治疗前降低(均P<0.01),且针刺组较西药组降低更显著(总积分:16.70±2.40 vs 15.70±3.01,P<0.01)。针刺组总有效率为95.0%(19/20),优于西药组的70.0%(14/20)(P<0.05)。结论:针刺天枢、大肠俞为主可明显改善肠易激综合征患者的临床症状,其疗效优于口服西药马来酸曲美布汀。展开更多
文摘In the present study, 36 cases of irritable bowel syndrome were treated by acupuncturing some acupoints selected according to differentiation of syndromes of traditional Chinese medicine.After 10 - 30 sessions of treatment, 35 cases were cured and the rest one case had improvement, with the effective rate being 100 %.
文摘以La_2O_3和Ta_2O_5为原材料,采用固相反应法制备了La_2La Ta O_7粉体。用X射线衍射技术、扫描电子显微镜、EDS电子能谱分析了粉体的相结构,显微形貌和元素组成。用激光颗粒度仪和比表面积分析仪分析了粉体的颗粒度及表面积,用可见光照射下亚甲基蓝的降解率分析了该粉体的光催化活性。结果表明,本文成功合成了纯净具有单一氟铝镁钠石结构的La_2La Ta O_7粉体,粉体具有明显的团聚现象,其平均颗粒度约为24μm,比表面积仅为0.463 m^2/g。经过150 min照射后,该粉体对亚甲基蓝的降解率达到68%,其较低的降解率可能与其较低的比表面积有关。
基金Supported by National Basic Research Program of China grant(to Zhu B),No.2011CB505201National Natural Science Foundation of China No.81130063 and No.81173345(to Zhu B and Gao X)
文摘AIM:To investigate the effect and mechanism of acupuncture at heterotopic acupoints on jejunal motility,particularly in pathological conditions.METHODS:Jejunal motility was assessed using a manometric balloon placed in the jejunum approximately18-20 cm downstream from the pylorus and filled with approximately 0.1 m L warm water in anesthetized normal rats or rats with diarrhea or constipation.The heterotopic acupoints including LI11(Quchi),ST37(Shangjuxu),BL25(Dachangshu),and the homotopic acupoint ST25(Tianshu),and were stimulated for 60 s by rotating acupuncture needles right and left at a frequency of 2 Hz.To determine the type of afferent fibers mediating the regulation of jejunal motility by manual acupuncture,the ipsilateral sciatic A or C fibers of ST37 were inactivated by local application of the A-fiber selective demyelination agent cobra venom or the C fiber blocker capsaicin.Methoctramine,a selective M2 receptor antagonist,was injected intravenously to identify a specific role for M2 receptors in mediating the effect of acupuncture on jejunal motility.RESULTS:Acupuncture at heterotopic acupoints,such as LI11 and ST37,increased jejunal motility not only in normal rats,but also in rats with constipation or diarrhea.In normal rats,manual acupuncture at LI11 or ST37 enhanced jejunal pressure from 7.34±0.19 cmH2O to 7.93±0.20 cm H2O,an increase of 9.05%±0.82%(P<0.05),and from 6.95±0.14 cm H2O to 8.97±0.22cm H2O,a significant increase of 27.44%±1.96%(P<0.01),respectively.In constipated rats,manual acupuncture at LI11 or ST37 increased intrajejunal pressure from8.17±0.31 cm H2O to 9.86±0.36 cm H2O,an increase of 20.69%±2.10%(P<0.05),and from 8.82±0.28cm H2O to 10.83±0.28 cm H2O,an increase of 22.81%±1.46%(P<0.05),respectively.In rats with diarrhea,MA at LI11 or ST37 increased intrajejunal pressure from 11.95±0.35 cm H2O to 13.96±0.39 cm H2O,an increase of 16.82%±2.35%(P<0.05),and tended to increase intrajejunal pressure(from 12.42±0.38 cm H2O to 13.05±0.38 cm H2O,an increase of 5.07%±1.08%,P>0.05),respectively.In contrast,acupuncture ST25,a homotopic acupoint,decreased not only intrajejunal pressure,but also significantly decreased frequency in normal rats and rats with constipation or diarrhea.Following demyelination of Aδfibers,acupuncture at ST37again augmented intrajejunal pressure to 121.48%±3.06%of baseline.Following capsaicin application for24 h,acupuncture at ipsilateral ST37 increased intrajejunal pressure significantly to 106.63%±1.26%of basallevels when compared to measurements prior to capsaicin treatment(P<0.05).Acupuncture at LI11,ST37,or BL25 significantly rescued methoctramine-mediated inhibition of jejunal motility amplitude from 42.83%±1.65%to 53.43%±1.95%of baseline(P<0.05),from45.15%±2.22%to 70.51%±2.34%of baseline(P<0.01),and from 38.03%±2.34%to 70.12%±2.22%of baseline(P<0.01),respectively.CONCLUSION:Acupuncture at heterotopic acupoints increases the amplitude of jejunal motility in rats.C fibers and M2 receptors predominantly and partially mediate the regulation of jejunal motility by acupuncture,respectively.
文摘Lumbar three point needling”, meaning puncturing Shenshu (BL 23), Dachangshu (BL 25) and Ciliao(BL 32) at the same time, is a commonly used acupuncture method in the treatment of lumbocrural diseases. Points supplemented according to symptoms: Weizhong(BL 40) is supplemented for lumbar vertebra hypertrophy spondylitis; Weizhong (BL 40) and Kunlun(BL 60) supplemented for acute lumbar muscle sprain; Zhibian (BL 54), Huantiao (GB 30) and Ahshi points supplemented for nervi cluniam superior inflammation, and Sanyinjiao (SP 6) and Mingmen(GV 4) supplemented for impotence. Gauge 28 2 cun long needles are used. The needles are inserted perpendicularly into Shenshu(BL 23), Dachengshu(BL 25) and Ciliao(BL 32) to a depth of about 1.2～1.5 cun. Other supplementary points are needled and stimulated with routine manipulations, generally the reducing method is used for excess syndrome, and the reinforcing method applied to deficiency syndrome. The author, on the basis of many years of clinical practice, considers that “lumbar three point needling” is fairly effective in treating lumbosacral diseases.
文摘目的:比较针刺天枢、大肠俞为主与口服西药马来酸曲美布汀治疗肠易激综合征的疗效差异。方法:将40例患者随机分针刺组和西药组,每组20例。针刺组针刺天枢、大肠俞为主,采用子午捣臼法,每天1次;西药组口服马来酸曲美布汀胶囊,每次2粒,每日3次,两组均治疗4周后评定疗效。结果:两组患者治疗后腹痛时间、腹痛频率、排便形状异常比率、排便通过异常比率、黏液便比率、排便时腹胀或腹痛积分均较治疗前降低(均P<0.01),且针刺组较西药组降低更显著(总积分:16.70±2.40 vs 15.70±3.01,P<0.01)。针刺组总有效率为95.0%(19/20),优于西药组的70.0%(14/20)(P<0.05)。结论:针刺天枢、大肠俞为主可明显改善肠易激综合征患者的临床症状,其疗效优于口服西药马来酸曲美布汀。
