In this paper,we present a simple method by combining surface wrinkling and template replication to create a series of hierarchical structures on polydimethylsiloxane（PDMS） elastomer.The primary stable lined pattern...In this paper,we present a simple method by combining surface wrinkling and template replication to create a series of hierarchical structures on polydimethylsiloxane（PDMS） elastomer.The primary stable lined patterns are formed by duplicating commercialized compact disk and digital versatile disk with PDMS.The secondary microscale patterns are from surface wrinkling,which is elicited by oxygen plasma（OP） treatment of the prestrained PDMS stamp followed with the prestrain release.By systematically varying the OP exposure duration,the prestrain,and the angle（θ） between the primary pattern orientation and the prestrain direction,we obtain highly ordered well-organized composite patterns from different patterning techniques and with different length scales and mechanical stabilities.展开更多
An animal model of epidemic(Japanese)B encephalitis was estabilisged by injecting theJin Wei Yah 1 stain of B encephalitis virus into the peritoneal cavity of mice.The ultrastructuralchanges of the nerve cells in thei...An animal model of epidemic(Japanese)B encephalitis was estabilisged by injecting theJin Wei Yah 1 stain of B encephalitis virus into the peritoneal cavity of mice.The ultrastructuralchanges of the nerve cells in their brains were studied,special attention being paid to some types ofnerve cell in the cerebellar cortex.The infectet Purkinje cells and especially the granular cells showedspecial and inter,sting pathological features.These were compared with the changes found in the in-fected nerve cells in the cerebral cortex,diencephalon and mesencephalon.A radiating structure consisting of a microveside-microtubule aggregation body at the centerand endoplastic reticulum or virus replication multivesicular structures around it was often found in thein fected nerve cells.Its morphological features were described in detail,and its significance and the se-quenoe of events of its development discussed.In the late stage of infection,virus particles were found in the nuclei of part of the necroticcells.It is considered that they entered the nuclei from the cytoplasm during or after the death of theinfected cells.The observation smade in this study have comfimed in the granular cell of the cerebellum theidea of Chert et al.that the encephalitis B virus particle can he formed in the perinudear cistem ofthe infected nerve cell,and have brought forth further information in this respect.The way of releaseof the virus particles from the infected nerve cells observed in this study is fundamentally consistentwith that observed by Chen et al.but most of the virus particles left the nerve cell via the cell pro-展开更多
基金Financial supports from the Natural Science Foundation of China(Nos.21074090 and 21374076)Tianjin Research Program of Application Foundation and Advanced Technology (No.13JCYBJC17100)
文摘In this paper,we present a simple method by combining surface wrinkling and template replication to create a series of hierarchical structures on polydimethylsiloxane（PDMS） elastomer.The primary stable lined patterns are formed by duplicating commercialized compact disk and digital versatile disk with PDMS.The secondary microscale patterns are from surface wrinkling,which is elicited by oxygen plasma（OP） treatment of the prestrained PDMS stamp followed with the prestrain release.By systematically varying the OP exposure duration,the prestrain,and the angle（θ） between the primary pattern orientation and the prestrain direction,we obtain highly ordered well-organized composite patterns from different patterning techniques and with different length scales and mechanical stabilities.
文摘An animal model of epidemic(Japanese)B encephalitis was estabilisged by injecting theJin Wei Yah 1 stain of B encephalitis virus into the peritoneal cavity of mice.The ultrastructuralchanges of the nerve cells in their brains were studied,special attention being paid to some types ofnerve cell in the cerebellar cortex.The infectet Purkinje cells and especially the granular cells showedspecial and inter,sting pathological features.These were compared with the changes found in the in-fected nerve cells in the cerebral cortex,diencephalon and mesencephalon.A radiating structure consisting of a microveside-microtubule aggregation body at the centerand endoplastic reticulum or virus replication multivesicular structures around it was often found in thein fected nerve cells.Its morphological features were described in detail,and its significance and the se-quenoe of events of its development discussed.In the late stage of infection,virus particles were found in the nuclei of part of the necroticcells.It is considered that they entered the nuclei from the cytoplasm during or after the death of theinfected cells.The observation smade in this study have comfimed in the granular cell of the cerebellum theidea of Chert et al.that the encephalitis B virus particle can he formed in the perinudear cistem ofthe infected nerve cell,and have brought forth further information in this respect.The way of releaseof the virus particles from the infected nerve cells observed in this study is fundamentally consistentwith that observed by Chen et al.but most of the virus particles left the nerve cell via the cell pro-
