This paper reviews the recent achievements made by our team in the mitigation of rockburst risk. It includes the development of neural network modeling on rockburst risk assessment for deep gold mines in South Af- ric...This paper reviews the recent achievements made by our team in the mitigation of rockburst risk. It includes the development of neural network modeling on rockburst risk assessment for deep gold mines in South Af- rica, an intelligent microseismicity monitoring system and sensors, an understanding of the rockburst evolution process using laboratory and in situ tests and monitoring, the establishment of a quantitative warning method for the location and intensities of different types of rockburst, and the development of measures for the dynamic control of rockburst. The mitigation of rockburst at the Hongtoushan copper mine is presented as an illustrative example.展开更多
Strata in red bed areas have typical characteristics of soft-hard interbedding and high sensitivity to water. Under the comprehensive action of internal stratigraphic structure and external hydrological factors, red b...Strata in red bed areas have typical characteristics of soft-hard interbedding and high sensitivity to water. Under the comprehensive action of internal stratigraphic structure and external hydrological factors, red bed landslides have highly complex spatiotemporal characteristics, presenting significant challenges to the prevention and control of landslide disasters in red bed areas, especially for slope and tunnel engineering projects. In this study, we applied an interdisciplinary approach combining small baseline subset interferometric synthetic aperture radar(SBAS-InSAR), deep displacement monitoring, and engineering geological surveying to identify the deformation mechanisms and spatiotemporal characteristics of the Abi landslide, an individual landslide that occurred in the red bed area of Western Yunnan, China. Surface deformation time series indicated that a basic deformation range developed by March 2020. Based on In SAR results and engineering geological analysis, the landslide surface could be divided into three zones: an upper sliding zone(US), a lower uplifted zone(LU), and a toe zone(Toe). LU was affected by the structure of the sliding bed with variable inclination. Using deep displacement curves combined with the geological profile, a set of sliding surfaces were identified between different lithology. The groundwater level standardization index(GLSI) and deformation normalization index(DNI) showed different quadratic relationships between US and LU. Verification using the Pearson correlation analysis shows that the correlation coefficients between model calculated results and measured data are 0.7933 and 0.7577, respectively, indicating that the DNI-GLSI models are applicable. A fast and short-lived deformation sub stage(ID-Fast) in the initial deformation stage was observed, and ID-Fast was driven by concentrated rainfall.展开更多
AIM: To characterize the profiles of alveolar hypoventilation during colonoscopies performed under sedoanalgesia with a combination of alfentanil and either midazolam or propofol. METHODS: Consecutive patients undergo...AIM: To characterize the profiles of alveolar hypoventilation during colonoscopies performed under sedoanalgesia with a combination of alfentanil and either midazolam or propofol. METHODS: Consecutive patients undergoing routine colonoscopy were randomly assigned to sedation with either propofol or midazolam in an open-labeled design using a titration scheme. All patients received 4 μg/kg per body weight alfentanil for analgesia and 3 L of supplemental oxygen. Oxygen saturation (SpO 2 ) was measured by pulse oximetry (POX), and capnography (PcCO 2 ) was continuously measured using a combined dedicated sensor at the ear lobe. Instances of apnea resulting in measures such as stimulation of the patient, a chin lift, a mask maneuver, or withholding of sedation were recorded. PcCO 2 values (as a parameter of sedation-induced hypoventilation) were compared between groups at the following distinct time points: baseline, maximal rise, termination of the procedure and 5 min after termination of the procedure. The number of patients in both study groups who regained baseline PcCO 2 values (± 1.5 mmHg) five minutes after the procedure was determined.RESULTS: A total of 97 patients entered this study. The data from 14 patients were subsequently excluded for clinical procedure-related reasons or for technical problems. Therefore, 83 patients (mean age 62 ± 13 years) were successfully randomized to receive propofol (n = 42) or midazolam (n = 41) for sedation. Most of the patients were classified as American Society of Anesthesiologists (ASA) Ⅱ [16 (38%) in the midazolam group and 15 (32%) in the propofol group] and ASA Ⅲ [14 (33%) and 13 (32%) in the midazolam and propofol groups, respectively]. A mean dose of 5 (4-7) mg of Ⅳ midazolam and 131 (70-260) mg of Ⅳ propofol was used during the procedure in the corresponding study arms. The mean SpO 2 at baseline (%) was 99 ± 1 for the midazolam group and 99 ± 1 for the propofol group. No cases of hypoxemia (SpO 2 < 85%) or apnea were recorded. However, an increase in PcCO 2 that indicated alveolar hypoventilation occurred in both groups after administration of the first drug and was not detected with pulse oximetry alone. The mean interval between the initiation of sedation and the time when the PcCO 2 value increased to more than 2 mmHg was 2.8 ± 1.3 min for midazolam and 2.8 ± 1.1 min for propofol. The mean maximal rise was similar for both drugs: 8.6 ± 3.7 mmHg for midazolam and 7.4 ± 3.2 mmHg for propofol. Five minutes after the end of the procedure, the mean difference from the baseline values was significantly lower for the propofol treatment compared with midazolam (0.9 ± 3.0 mmHg vs 4.3 ± 3.7 mmHg, P = 0.0000169), and significantly more patients in the propofol group had regained their baseline value ± 1.5 mmHg (32 of 41vs 12 of 42,P = 0.0004). CONCLUSION: A significantly higher number of patients sedated with propofol had normalized PcCO 2 values five minutes after sedation when compared with patients sedated with midazolam.展开更多
The deep dielectric charging effect monitor(DDCEM)has been designed to study the internal charging effect by measuring the charging currents and potentials inside the spacecraft.It is equipped on three Chinese navigat...The deep dielectric charging effect monitor(DDCEM)has been designed to study the internal charging effect by measuring the charging currents and potentials inside the spacecraft.It is equipped on three Chinese navigation satellites in a circular medium earth orbit(MEO)with 22000 km average height and 55°inclinations.Numerical simulation based on the Geant4-RIC method was used to evaluate the data of DDCEM.The data during May to November 2019 on one of the three satellites show that the charging currents of DDCEM were negatively enhanced when the satellite moved into the outer radiation belt.The currents reached the negative maximum during a significant electron enhancement in September 2019.Positive currents were also detected besides negative currents that were caused by the deposition of electrons in the sensor.The causation of positive currents in the space environment may be that the low-energy electrons cannot penetrate the satellite skin and make it charging to negative potential,the reference ground of DDCEM that is connected to the satellite skin drops below zero by the low-energy electrons so that the output currents turn to positive.Ground experiment was used to simulate the causation of positive currents and the result verified our theory.展开更多
基金The authors gratefully acknowledge financial support from the National Natural Science Foundation of China (51621006, 413200104005, and 11232014).
文摘This paper reviews the recent achievements made by our team in the mitigation of rockburst risk. It includes the development of neural network modeling on rockburst risk assessment for deep gold mines in South Af- rica, an intelligent microseismicity monitoring system and sensors, an understanding of the rockburst evolution process using laboratory and in situ tests and monitoring, the establishment of a quantitative warning method for the location and intensities of different types of rockburst, and the development of measures for the dynamic control of rockburst. The mitigation of rockburst at the Hongtoushan copper mine is presented as an illustrative example.
基金funded by the List of Key Science and Technology Projects in the Transportation Industry of the Ministry of Transport in 2021(Grant No.2021-MS4-105)the Science and Technology Project of Yunnan Traffic Planning Design Institute Co.,Ltd.(Grant No.ZL-2021-03)+7 种基金the Postgraduate Scientific Research Innovation Project of Yunnan University(Grant No.2020192)the National Key Research and Development Program of China(Grant No.2018YFC1504906)the National Natural Science Foundation of China(Grant No.41872251)the Plateau Mountain Ecology and Earth’s Environment Discipline Construction Project(Grant No.C1762101030017)the Joint Foundation Project between Yunnan Science and Technology Department and Yunnan University(Grants No.C176240210019 and 2019FY003017)the Yunnan Postdoctoral Foundation(Grant No.C615300504031)the China Geological Survey Project(Grant No.DD20221824)the science and technology innovation program of the department of transportation,Yunnan province,China(No.2019301)。
文摘Strata in red bed areas have typical characteristics of soft-hard interbedding and high sensitivity to water. Under the comprehensive action of internal stratigraphic structure and external hydrological factors, red bed landslides have highly complex spatiotemporal characteristics, presenting significant challenges to the prevention and control of landslide disasters in red bed areas, especially for slope and tunnel engineering projects. In this study, we applied an interdisciplinary approach combining small baseline subset interferometric synthetic aperture radar(SBAS-InSAR), deep displacement monitoring, and engineering geological surveying to identify the deformation mechanisms and spatiotemporal characteristics of the Abi landslide, an individual landslide that occurred in the red bed area of Western Yunnan, China. Surface deformation time series indicated that a basic deformation range developed by March 2020. Based on In SAR results and engineering geological analysis, the landslide surface could be divided into three zones: an upper sliding zone(US), a lower uplifted zone(LU), and a toe zone(Toe). LU was affected by the structure of the sliding bed with variable inclination. Using deep displacement curves combined with the geological profile, a set of sliding surfaces were identified between different lithology. The groundwater level standardization index(GLSI) and deformation normalization index(DNI) showed different quadratic relationships between US and LU. Verification using the Pearson correlation analysis shows that the correlation coefficients between model calculated results and measured data are 0.7933 and 0.7577, respectively, indicating that the DNI-GLSI models are applicable. A fast and short-lived deformation sub stage(ID-Fast) in the initial deformation stage was observed, and ID-Fast was driven by concentrated rainfall.
文摘AIM: To characterize the profiles of alveolar hypoventilation during colonoscopies performed under sedoanalgesia with a combination of alfentanil and either midazolam or propofol. METHODS: Consecutive patients undergoing routine colonoscopy were randomly assigned to sedation with either propofol or midazolam in an open-labeled design using a titration scheme. All patients received 4 μg/kg per body weight alfentanil for analgesia and 3 L of supplemental oxygen. Oxygen saturation (SpO 2 ) was measured by pulse oximetry (POX), and capnography (PcCO 2 ) was continuously measured using a combined dedicated sensor at the ear lobe. Instances of apnea resulting in measures such as stimulation of the patient, a chin lift, a mask maneuver, or withholding of sedation were recorded. PcCO 2 values (as a parameter of sedation-induced hypoventilation) were compared between groups at the following distinct time points: baseline, maximal rise, termination of the procedure and 5 min after termination of the procedure. The number of patients in both study groups who regained baseline PcCO 2 values (± 1.5 mmHg) five minutes after the procedure was determined.RESULTS: A total of 97 patients entered this study. The data from 14 patients were subsequently excluded for clinical procedure-related reasons or for technical problems. Therefore, 83 patients (mean age 62 ± 13 years) were successfully randomized to receive propofol (n = 42) or midazolam (n = 41) for sedation. Most of the patients were classified as American Society of Anesthesiologists (ASA) Ⅱ [16 (38%) in the midazolam group and 15 (32%) in the propofol group] and ASA Ⅲ [14 (33%) and 13 (32%) in the midazolam and propofol groups, respectively]. A mean dose of 5 (4-7) mg of Ⅳ midazolam and 131 (70-260) mg of Ⅳ propofol was used during the procedure in the corresponding study arms. The mean SpO 2 at baseline (%) was 99 ± 1 for the midazolam group and 99 ± 1 for the propofol group. No cases of hypoxemia (SpO 2 < 85%) or apnea were recorded. However, an increase in PcCO 2 that indicated alveolar hypoventilation occurred in both groups after administration of the first drug and was not detected with pulse oximetry alone. The mean interval between the initiation of sedation and the time when the PcCO 2 value increased to more than 2 mmHg was 2.8 ± 1.3 min for midazolam and 2.8 ± 1.1 min for propofol. The mean maximal rise was similar for both drugs: 8.6 ± 3.7 mmHg for midazolam and 7.4 ± 3.2 mmHg for propofol. Five minutes after the end of the procedure, the mean difference from the baseline values was significantly lower for the propofol treatment compared with midazolam (0.9 ± 3.0 mmHg vs 4.3 ± 3.7 mmHg, P = 0.0000169), and significantly more patients in the propofol group had regained their baseline value ± 1.5 mmHg (32 of 41vs 12 of 42,P = 0.0004). CONCLUSION: A significantly higher number of patients sedated with propofol had normalized PcCO 2 values five minutes after sedation when compared with patients sedated with midazolam.
基金supported by the National Natural Science Foundation of China (Grant No. 41374181)the Beijing Municipal Natural Science Foundation (Grant No. 3184048)
文摘The deep dielectric charging effect monitor(DDCEM)has been designed to study the internal charging effect by measuring the charging currents and potentials inside the spacecraft.It is equipped on three Chinese navigation satellites in a circular medium earth orbit(MEO)with 22000 km average height and 55°inclinations.Numerical simulation based on the Geant4-RIC method was used to evaluate the data of DDCEM.The data during May to November 2019 on one of the three satellites show that the charging currents of DDCEM were negatively enhanced when the satellite moved into the outer radiation belt.The currents reached the negative maximum during a significant electron enhancement in September 2019.Positive currents were also detected besides negative currents that were caused by the deposition of electrons in the sensor.The causation of positive currents in the space environment may be that the low-energy electrons cannot penetrate the satellite skin and make it charging to negative potential,the reference ground of DDCEM that is connected to the satellite skin drops below zero by the low-energy electrons so that the output currents turn to positive.Ground experiment was used to simulate the causation of positive currents and the result verified our theory.