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Devastating complication of negative pressure wound therapy after deep inferior epigastric perforator free flap surgery:A case report 被引量:1
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作者 SooA Lim Dong Yun Lee +3 位作者 BumSik Kim Jung Soo Yoon Yea Sik Han SuRak Eo 《World Journal of Clinical Cases》 SCIE 2023年第1期143-149,共7页
BACKGROUND Thermal injuries on free transferred or replanted tissues resulting from loss of sensibility are an infrequent occurrence.They require immediate and appropriate management before they progress to an irrever... BACKGROUND Thermal injuries on free transferred or replanted tissues resulting from loss of sensibility are an infrequent occurrence.They require immediate and appropriate management before they progress to an irreversible condition.Although negative pressure wound therapy(NPWT)can prevent wound progression by increasing microcirculation,the inappropriate application of NPWT on complicationthreatened transferred and replanted tissues can induce an adverse effect.CASE SUMMARY A 48-year-old woman who underwent immediate breast reconstruction with a deep inferior epigastric artery perforator free flap.While applying a heating pad directly to the flap site,she sustained a deep second to third-degree contact burn over 30%of the transferred flap on postoperative 7 d.As the necrotic changes had progressed,we applied an NPWT dressing over the burned area after en-bloc debridement of the transferred tissues on postoperative 21 d.After 4 d of NPWT application,the exposed fatty tissues of the flap changed to dry and browncolored necrotic tissues.Upon further debridement,we noted that the wound gradually reached total necrosis with a collapsed vascular pedicle of deep inferior epigastric artery.CONCLUSION Although NPWT has been shown to be successful for treating various wound types,the significant risk of NPWT application in short-lasting reconstructed flap wounds after thermal injury should be reminded. 展开更多
关键词 Negative Pressure wound Therapy COMPLICATIONS Breast reconstruction deep inferior epigastric artery perforator Free flap Burn injury Case report
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To investigate the clinical effect of modified closed negative pressure suction technique combined with flap transplantation on the treatment of deep chronic refractory wounds
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作者 Zhihui Hou Mingjuan Gu 《Discussion of Clinical Cases》 2019年第1期11-14,共4页
Objective:To investigate the clinical effect of modified closed negative pressure suction technique combined with flap transplantation on the treatment of deep chronic refractory wounds.Methods:During March of 2015 to... Objective:To investigate the clinical effect of modified closed negative pressure suction technique combined with flap transplantation on the treatment of deep chronic refractory wounds.Methods:During March of 2015 to April of 2018,52 cases of patients with deep chronic refractory wounds were selected as research objects.They were divided into the control group and the treatment group by use of the random number table method,with 26 cases in each group.Among them,the control group was given conventional debridement combined with flap reconstruction,and the treatment group was treated with modified closed negative pressure suction technique combined with flap transplantation to observe the clinical effect.Results:(1)According to the analysis on the effect of flap transplantation,the excellent and good rate of the treatment group was 92.3%,and in the control group,it was 76.9%(p<0.05).(2)According to the statistics,the incidence of complications in the treatment group was lower than that in the control group(p<0.05).Conclusions:Modified closed negative pressure suction technique combined with flap transplantation has a good effect on the treatment of deep chronic refractory wounds with fewer complications. 展开更多
关键词 Modified closed negative pressure suction technique Flap transplantation deep chronic refractory wounds
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Design of axial flaps with color Doppler flow imaging technique for repairing deep wounds of heels
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作者 黎洪棉 《外科研究与新技术》 2005年第3期215-215,共1页
To report the methods and effect of axial pattern flap on lower limb in repairing deep wounds of heels by using color Doppler flow imaging (CDFI) technique so as to solve the ever before problems that the vessel can n... To report the methods and effect of axial pattern flap on lower limb in repairing deep wounds of heels by using color Doppler flow imaging (CDFI) technique so as to solve the ever before problems that the vessel can not be displayed in designing axial flap.Methods Suitable axial flaps on lower limbs were selected according to the character of the wounds.There were 25 flaps including 10 cases of the distal-based sural neurovascular flap,nine medial sole flap and six medial leg flap.All the axial pattern flaps were designed on the basis of traditional design ways before operation;then,CDFI appliance with high resolution was used to examine the starting spot,exterior diameter,trail and length of the flap’s major artery.The flaps were redesigned according to the results of CDFI and transferred to cover the wounds.In the meantime,both the results of operation and examination were compared.Results The major artery’s starting spot,exterior diameter,trail and anatomic layers were displayed clearly,in consistency with the results of operation.The flaps survived completely and recovered well,with perfect appearance,color and arthral function.Conclusion CDFI is a simple,macroscopic and atraumatic method for designing the axial pattern flap on lower limb,can provide more scientific and accurate evidence for preoperative determination of flap transplantation and is worthy of clinical application.10 refs,4 figs,2 tabs. 展开更多
关键词 Design of axial flaps with color Doppler flow imaging technique for repairing deep wounds of heels
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Sternal Reconstruction of Deep Sternal Wound Infections Following Median Sternotomy by Single-stage Muscle Flaps Transposition 被引量:1
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作者 Song Wu Feng Wan +4 位作者 Yong-shun Gao Zhe Zhang Hong Zhao Zhong-qi Cui Ji-yan Xie 《Chinese Medical Sciences Journal》 CAS CSCD 2014年第4期208-213,共6页
Objective To assess clinical effectiveness of using bilateral pectoralis major or plus rectus abdominis muscle flaps in treating deep sternal wound infection(DSWI) following median sternotomy. Methods Between January ... Objective To assess clinical effectiveness of using bilateral pectoralis major or plus rectus abdominis muscle flaps in treating deep sternal wound infection(DSWI) following median sternotomy. Methods Between January 2009 and December 2013, 19 patients with DSWI after median sternotomy for cardiac surgery were admitted to our hospital, including 14 males(73.7%) and 5 females(26.3%), aged 55±13(18-78) years. According to the Pairolero classification of infected median sternotomies, 3(15.8%) patients were type II, and the other 16(84.2%) were type III. Surgical procedure consisted of adequate debridement of infected sternum, costal cartilage, granulation, steel wires, suture residues and other foreign substances. Sternal reconstruction used the bilateral pectoralis major or plus rectus abdominis muscle flaps to obliterate dead space. The drainage tubes were placed and connected to a negative pressure generator for adequate drainage. Results There were no intraoperative deaths. In 15 patients(78.9%), bilateral pectoral muscle flaps were mobilized sufficiently to cover and stabilize the defect created by wound debridement. 4 patients(21.0%) needed bilateral pectoral muscle flaps plus rectus abdominis muscle flaps because their pectoralis major muscle flaps could not reach the lowest portion of the wound. 2 patients(10.5%) presented with subcutaneous infection, and 3 patients(15.8%) had hematoma. They recovered following local debridement and medication. 17 patients(89.5%) were examined at follow-up 12 months later, all healed and having stable sternum. No patients showed infection recurrence during the follow-up period over 12 months. Conclusion DSWI following median sternotomy may be effectively managed with adequate debridement of infected tissues and reconstruction with bilateral pectoralis major muscle or plus rectus abdominis muscle flap transposition. 展开更多
关键词 median STERNOTOMY deep sternal wound infections sternal OSTEOMYELITIS sing-stage pectoralis major MUSCLE FLAP RECTUS abdominis MUSCLE FLAP
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Tailoring Food Biopolymers into Biogels for Regenerative Wound Healing and Versatile Skin Bioelectronics 被引量:1
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作者 Qiankun Zeng Qiwen Peng +3 位作者 Fangbing Wang Guoyue Shi Hossam Haick Min Zhang 《Nano-Micro Letters》 SCIE EI CAS CSCD 2023年第9期461-478,共18页
An increasing utilization of wound-related therapeutic materials and skin bioelectronics urges the development of multifunctional biogels for personal therapy and health management.Nevertheless,conventional dressings ... An increasing utilization of wound-related therapeutic materials and skin bioelectronics urges the development of multifunctional biogels for personal therapy and health management.Nevertheless,conventional dressings and skin bioelectronics with single function,mechanical mismatches,and impracticality severely limit their widespread applications in clinical.Herein,we explore a gelling mechanism,fabrication method,and functionalization for broadly applicable food biopolymers-based biogels that unite the challenging needs of elastic yet injectable wound dressing and skin bioelectronics in a single system.We combine our biogels with functional nanomaterials,such as cuttlefish ink nanoparticles and silver nanowires,to endow the biogels with reactive oxygen species scavenging capacity and electrical conductivity,and finally realized the improvement in diabetic wound microenvironment and the monitoring of electrophysiological signals on skin.This line of research work sheds light on preparing food biopolymers-based biogels with multifunctional integration of wound treatment and smart medical treatment. 展开更多
关键词 Food biopolymers Biogels Skin bioelectronics deep wound Superficial wound
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Deep Sternal Wound Infections after Coronary Artery Bypass Grafting: Analysis of 29 Cases from Iraq
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作者 Raghda Basil Ismael Alkhateeb Asmaa Saleem Esmail Ah-Ghurabi +1 位作者 Laith Saleh Alkaaby Abdulsalam Y. Taha 《World Journal of Cardiovascular Surgery》 2022年第7期153-172,共20页
Background: Deep sternal wound infection (DSWI), or mediastinitis, is a devastating complication of coronary artery bypass grafting (CABG). This prospective study aimed to assess our management of DSWI in view of the ... Background: Deep sternal wound infection (DSWI), or mediastinitis, is a devastating complication of coronary artery bypass grafting (CABG). This prospective study aimed to assess our management of DSWI in view of the published literature. Methods: Over 2-years (ending in January 2016), 29 patients (20 males) developed DSWI amongst 520 patients who underwent standard CABG surgeries (5.6%). Pre-, intra- and postoperative variables were documented. Whenever possible, the infections were culture-verified. Besides antibiotics, patients received one or more of the following therapies: drainage, debridement, closed irrigation, sternal re-wiring, vacuum-assisted closure (VAC), and bone resection. Results: the male to female ratio was 2.2:1. Mean age was 58.1 ± 7.3 years. The mean body mass index (BMI) was 27.9 ± 3.4 kg/m<sup>2</sup>. There were 18, 16 and 11 patients with diabetes mellitus (DM), hypertension and chronic obstructive pulmonary disease (COPD) respectively. Cardiopulmonary bypass (CPB) was utilized in 26 (89.7%) patients with a mean time of 117.5 ± 23.3 minutes. Most surgeries (n = 21, 72.4%) lasted 5 - 6 hrs. According to Pairolero classification, there were 3 (10.3%) Type I, 22 (75.9%) Type II and 4 (13.8%) Type III infections. Four (13.8%) cases were culture-verified. Twenty-three (79.3%) DSWIs were surgically managed. Sternal re-wiring was performed in 14 (48.3%) cases while VAC was added to other therapies in 2 (6.9%) patients. DSWIs completely resolved in 18 (62.0%) patients within 3 - 24 weeks while two (6.9%) patients died within 30 days. Conclusion: We have identified six independent risk factors for DSWI (male gender, obesity, DM, hypertension, COPD and CPB), five of them are modifiable. 展开更多
关键词 deep Sternal wound Infection MEDIASTINITIS Coronary Artery Bypass Grafting Median Sternotomy Vacuum-Assisted Closure wound Debridement
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Intraoperative vs 24-Hour Administration of Cefamandole to Prevent Deep Sternal Wound Infection and Endocarditis after Adult Cardiac Surgery
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作者 Jean-Michel Maillet Stephane Thierry +5 位作者 Gregoire Oghina Paul Le Besnerais Patrick Mesnildrey Nicolas Bonnet Francois Simoneau Denis Brodaty 《Open Journal of Anesthesiology》 2013年第9期383-387,共5页
Background and Objectives: Duration of antibiotic prophylaxis for cardiac surgery is still debated and controversial. International guidelines are vague: French guidelines recommend an intraoperative administration, w... Background and Objectives: Duration of antibiotic prophylaxis for cardiac surgery is still debated and controversial. International guidelines are vague: French guidelines recommend an intraoperative administration, while the Society of Thoracic Surgeons’ guidelines suggest that optimal postoperative prophylactic antibiotics be given for 48 hours or less. Very few studies have compared the same antibiotic with 2 different administration durations. The study was designed to compare the efficacy of 24-hour administration of cefamandole vs intraoperative cefamandole to prevent deep sternal wound infection and endocarditis after cardiac surgery. Methods: This retrospective and observational study compared the rates of severe surgical site infections (deep sternal wound infection, endocarditis) after cardiac surgery between period 1, 01/01/2008-31/08/2008, with 24-hour administration of cefamandole, and period 2, 01/09/2008-30/04/2009 with intraoperative cefamandole. Results: Among 933 patients, 14 patients (1.5%) developed surgical site infection during the 16-month study: 1.3% during the first period and 1.7% during the second (ns). The populations (470 patients in period 1 and 463 in period 2) were homogeneous and comparable for pre-, intra- and postoperative characteristics. Surgical site infection characteristics (pathogens involved, time to diagnosis) and consequences (longer hospital stay, outcomes) were comparable in the 2 groups. Conclusions: Intraoperative cefamandole was as safe as its 24-hour administration to prevent deep sternal wound infection and endocarditis after adult cardiac surgery. 展开更多
关键词 Surgical Site Infection deep Sternal wound Infection ENDOCARDITIS Antibiotic Prophylaxis Cardiac Surgery Cefamandole
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罂粟碱注射液联合重组牛碱性成纤维细胞生长因子治疗深度烧伤残余创面的临床研究
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作者 林冠 王佳坤 +3 位作者 戴立 林淑瑜 欧阳容兰 刘江涛 《临床和实验医学杂志》 2024年第20期2223-2227,共5页
目的观察罂粟碱注射液联合重组牛碱性成纤维细胞生长因子(rb-bFGF)治疗深度烧伤残余创面的临床疗效。方法回顾性选取2019年1月至2023年6月入中国人民解放军联勤保障部队第九一〇医院治疗的深度烧伤患者80例作为研究对象,参考用药不同分... 目的观察罂粟碱注射液联合重组牛碱性成纤维细胞生长因子(rb-bFGF)治疗深度烧伤残余创面的临床疗效。方法回顾性选取2019年1月至2023年6月入中国人民解放军联勤保障部队第九一〇医院治疗的深度烧伤患者80例作为研究对象,参考用药不同分为联合用药组(n=40)与单独用药组(n=40)。联合用药组采用rb-bFGF与罂粟碱注射液联合治疗,于5 cm×5 cm无菌纱布上涂抹300 IU/cm^(2)rb-bFGF之后将其于创面上覆盖,每日换药1次,肌肉注射罂粟碱注射液每日30 mg,每日2次。单独用药组单用rb-bFGF,用法同联合用药组。两组均持续治疗14 d。比较两组患者的治疗前及治疗后14 d的血清炎症因子[肿瘤坏死因子-α(TNF-α)、白细胞介素(IL)-10、IL-6、IL-4、IL-1β]水平,治疗后3、7、10、14 d的创面分泌物评分和创缘反应评分,创面愈合时间,总有效率及不良反应发生率。结果联合用药组患者治疗后14 d的血清TNF-α、IL-6、L-1β水平分别为(65.27±8.77)、(105.21±9.14)、(20.21±1.18)μg/L,均明显低于单独用药组[(89.26±9.32)、(128.32±8.21)、(29.36±1.28)μg/L],IL-10、IL-4水平分别为(537.75±22.92)、(162.42±17.79)μg/L,均明显高于单独用药组[(497.41±22.63)、(137.27±17.41)μg/L],差异均有统计学意义(P<0.05)。联合用药组患者治疗后3、7、10、14 d创面分泌物评分分别为(1.64±0.25)、(0.97±0.24)、(0.78±0.20)、(0.38±0.11)分,均低于单独用药组[(1.82±0.29)、(1.28±0.26)、(1.04±0.24)、(0.65±0.14)分],差异均有统计学意义(P<0.05)。联合用药组患者治疗后3、7、10、14 d创缘反应评分分别为(0.82±0.13)、(0.39±0.09)、(0.20±0.04)、(0.04±0.02)分,均低于单独用药组[(1.19±0.21)、(0.68±0.11)、(0.49±0.10)、(0.21±0.04)分],差异均有统计学意义(P<0.05)。联合用药组患者治疗后创面愈合时间为(22.84±3.02)d,明显短于单独用药组[(27.94±3.14)d],差异有统计学意义(P<0.05)。联合用药组患者的治疗后总有效率为97.50%,明显高于单独用药组(80.00%),差异有统计学意义(P<0.05)。两组均未发生皮肤刺痛及红痒等不良反应。结论深度烧伤残余创面治疗中,与单用rb-bFGF治疗相比,罂粟碱注射液联合rb-bFGF的临床疗效明显提高,可进一步减轻炎症反应,加速创面愈合,且无明显不良反应。 展开更多
关键词 深度烧伤残余创面 罂粟碱注射液 重组牛碱性成纤维细胞生长因子 临床疗效
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自制中草药油对大鼠深度烧伤创面的疗效评价
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作者 杜宪 蔡霞 +2 位作者 任纪祯 苏鲁安 陈振雨 《中国美容医学》 CAS 2024年第9期45-48,共4页
目的:经过建立Wister大鼠深度烧伤模型,探讨自制中草药油机制及促进深度烧伤创面愈合的临床疗效。方法:选取清洁健康雄性Wister大鼠60只为研究对象,将建模成功的大鼠依据治疗方式分为对照组30只和观察组30只。对照组使用生理盐水予以清... 目的:经过建立Wister大鼠深度烧伤模型,探讨自制中草药油机制及促进深度烧伤创面愈合的临床疗效。方法:选取清洁健康雄性Wister大鼠60只为研究对象,将建模成功的大鼠依据治疗方式分为对照组30只和观察组30只。对照组使用生理盐水予以清创后,将凡士林纱布遮盖包裹创面,并用敷贴稳固;观察组采用自制中草药油涂抹,涂抹均匀后予以纱布进行固定,每日进行换药1次。对比两组治疗后第3、7、14、21天创面愈合情况与创面愈合率、HE染色法观察大鼠烧伤创面皮肤成纤维细胞数及毛细血管数,免疫组化染色法检测大鼠烧伤创面皮肤组织表皮生长因子(Epidermal growth factor,EGF)、血管内皮生长因子(Vascular endothelial growth factor,VEGF)水平。结果:治疗后第3、7、14、21天,两组创面愈合率均升高,且观察组明显高于对照组(P<0.05);观察组创面愈合面积和渗出液均小于对照组;两组创面成纤维细胞数和毛细血管数均上升,且观察组明显高于对照组(P<0.05);两组EGF、VEGF水平均上升,且观察组比对照组高(P<0.05)。结论:利用自制中草药油治疗大鼠深度烧伤创面,可有效增加创面成纤维细胞数和毛细血管数,提高创面EGF、VEGF水平,促进了创面愈合情况,为临床深度烧伤创面用药提供有力理论价值。 展开更多
关键词 自制中草药油 大鼠 深度烧伤 创面愈合 疗效评价
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负压创面治疗技术联合削痂植皮术在深度烧伤创面修复中的应用
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作者 付永峰 王嘉欣 +1 位作者 单楠 张馨元 《中国美容医学》 CAS 2024年第10期89-93,共5页
目的:探究负压创面治疗技术(Negative pressure wound therapy,NPWT)联合削痂植皮术修复深度烧伤后创面的疗效。方法:选取2020年1月-2023年1月笔者医院收治的112例深度烧伤患者,按随机数字表法分为实验组(56例)和对照组(56例)。对照组... 目的:探究负压创面治疗技术(Negative pressure wound therapy,NPWT)联合削痂植皮术修复深度烧伤后创面的疗效。方法:选取2020年1月-2023年1月笔者医院收治的112例深度烧伤患者,按随机数字表法分为实验组(56例)和对照组(56例)。对照组采用削痂植皮术治疗,实验组采用NPWT联合削痂植皮术进行治疗。统计比较两组患者临床疗效、创面愈合情况、疼痛评分[视觉模拟评分法(Visual analogue scale,VAS)]、外观满意度评分、炎症因子水平[肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)]、并发症及瘢痕情况[温哥华瘢痕量表(Vancouver scar scale,VSS)]。结果:治疗后,实验组临床疗效优于对照组,创面愈合时间短于对照组,差异均有统计学意义(P<0.05);植皮术后7 d,实验组创面愈合率、皮片成活率、外观满意度评分均高于对照组(P<0.05),疼痛VAS评分、TNF-α和IL-6水平均低于对照组(P<0.05);治疗期间,实验组总并发症发生率低于对照组(P<0.05);植皮术后6个月,实验组VSS各评分及总分均低于对照组(P<0.05)。结论:NPWT联合削痂植皮术修复深度烧伤后创面疗效良好,可有效促进创面愈合,降低疼痛感,减少瘢痕形成,改善患者预后,值得临床应用。 展开更多
关键词 负压创面治疗技术 削痂 植皮 深度烧伤 创面
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Clinical analysis of patients with deep sternal wound infection-induced sepsis:a retrospective cohort study
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作者 Bin Song Zhentian Cui +3 位作者 Hongyan Ju Yue Sun Dandan Liu Guanggang Li 《Emergency and Critical Care Medicine》 2024年第2期67-73,共7页
Background:This study aimed to summarize the clinical characteristics of patients with deep sternal wound infection-induced sepsis after median sternotomy and improve the treatment outcomes of infection-related sepsis... Background:This study aimed to summarize the clinical characteristics of patients with deep sternal wound infection-induced sepsis after median sternotomy and improve the treatment outcomes of infection-related sepsis.Methods:A retrospective cohort study was conducted on 21 patients with deep sternal wound infection-induced sepsis after median sternotomy who were admitted to the Department of Critical Care.The clinical manifestations,laboratory test results,infection control,and organ and nutritional support of the patients were summarized,and the follow-up data were obtained.Results:The primary symptoms of deep sternal wound infection-induced sepsis included dyspnea,high fever,chills,and altered state of consciousness.Laboratory test results revealed increased inflammatory markers and decreased oxygenation index.Renal and liver function injury were observed in 8 and 4 patients,respectively;18 and 12 patients demonstrated elevated D-dimer and N-terminal Pro B type natriuretic peptide levels,respectively.Of the 8 patients whose wound secretions tested positive for bacteria,Acinetobacter baumannii and Staphylococcus aureus infections were present in 6 and 2 patients,respectively.One of the 6 patients whose blood cultures tested positive for bacteria demonstrated Candida albicans infection.Fifteen patients received ventilator-assisted ventilation and 2 patients received renal replacement therapy.Of all the 21 patients,17 were cured,2 died,and 2 were discharged.Conclusion:Postmedian sternotomy sepsis attributed to a deep sternal wound infection usually results from a preexisting condition.The most prominent clinical manifestation is dyspnea,which is sometimes accompanied by the impairment of organ function.Infection prevention,proper nutrition support,and maintenance of healthy organ function are the cornerstones for successful treatment outcomes. 展开更多
关键词 Clinical analysis deep sternal wound infection SEPSIS
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深部胸骨切口感染预防及治疗的研究进展
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作者 林楠 张瑞 肖虎 《新医学》 CAS 2024年第3期193-197,共5页
深部胸骨切口感染(DSWI)是正中胸骨切开术后罕见但严重的一种并发症。DSWI的治疗周期长,预后不理想,对患者的生活质量和心理健康造成了一定影响。该现状的改善需要临床医师的多学科合作,医师术前及时识别危险因素,并采取有效的预防措施... 深部胸骨切口感染(DSWI)是正中胸骨切开术后罕见但严重的一种并发症。DSWI的治疗周期长,预后不理想,对患者的生活质量和心理健康造成了一定影响。该现状的改善需要临床医师的多学科合作,医师术前及时识别危险因素,并采取有效的预防措施,术后一旦发现切口感染及时处理,可避免感染进展到胸骨及纵膈。在明确DSWI的情况下,整形外科医师选择适合患者的治疗方案,及时控制感染实现胸骨重建。目前,DSWI的预防尚未引起足够的重视,治疗多依赖于医师自身的经历与理解,缺乏共识。该文对DSWI的预防和治疗的相关进展作一综述。 展开更多
关键词 深部胸骨切口感染 正中胸骨切开术 心脏手术 预防 治疗
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对冲引流治疗骨科术后深部感染的临床效果及对血清炎症指标的影响
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作者 李泉胜 邵巍 +1 位作者 徐建勇 毕凌峰 《中国医学创新》 CAS 2024年第2期58-62,共5页
目的:探讨对冲引流治疗骨科术后深部感染的临床效果及对血清炎症指标的影响。方法:选取2020年7月—2023年4月贵溪市人民医院收治的骨科术后深部感染患者60例,随机分为对照组和观察组,每组30例。对照组采用常规扩创术治疗,观察组在对照... 目的:探讨对冲引流治疗骨科术后深部感染的临床效果及对血清炎症指标的影响。方法:选取2020年7月—2023年4月贵溪市人民医院收治的骨科术后深部感染患者60例,随机分为对照组和观察组,每组30例。对照组采用常规扩创术治疗,观察组在对照组基础上联合对冲引流治疗。比较两组创口愈合率、疼痛评分、血清炎症指标[白细胞计数(WBC)、C反应蛋白(CRP)、红细胞沉降率(ESR)]及凝血功能指标[活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)、凝血酶时间(TT)、纤维蛋白原(FIB)]水平。结果:观察组创口愈合率(93.33%)高于对照组(73.33%)(P<0.05)。术后3、7、14 d,观察组视觉模拟评分法(VAS)评分均低于对照组(P<0.05)。术后14 d,观察组WBC、CRP、ESR、FIB水平均低于对照组,APTT、PT、TT均短于对照组(P<0.05)。结论:对冲引流治疗骨科术后深部感染能提高创口愈合率,减轻疼痛程度,且能抑制血清炎症因子水平,改善凝血功能。 展开更多
关键词 深部感染 对冲引流 创口愈合 炎症因子
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基于行动研究法的健康管理联合VSD对深度烧伤患者心理状态及创面修复效果的影响
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作者 蔡淼 侯丽名 《中国美容医学》 CAS 2024年第10期116-120,共5页
目的:探究基于行动研究法的健康管理联合负压封闭引流(Vacuum sealing drainage,VSD)技术对深度烧伤患者心理状态及创面修复效果的影响。方法:选取2021年9月-2023年6月笔者科室收治的98例深度烧伤患者,经随机单双号法分为常规组(单号,n=... 目的:探究基于行动研究法的健康管理联合负压封闭引流(Vacuum sealing drainage,VSD)技术对深度烧伤患者心理状态及创面修复效果的影响。方法:选取2021年9月-2023年6月笔者科室收治的98例深度烧伤患者,经随机单双号法分为常规组(单号,n=49)和行动法组(双号,n=49),两组均实施VSD技术治疗,常规组采用常规护理干预,行动法组采用基于行动研究法的健康管理。比较两组患者疾病认知水平、负性情绪[自我感受负担量表(Self-perceived burden scale,SPBS)]、伤残接受度[伤残接受度量表(Acceptance of disability scale,AODS)]、生活质量[中文版精简烧伤健康量表(Burn specific health scale-brief,BSHS-B)]、创面美观度[温哥华瘢痕量表(Vancouver scar scale,VSS)]评分及护理满意度。结果:干预后,行动法组患者对疾病的认知情况评分、AODS、BSHS-B评分及护理满意度均高于常规组,SPBS、VSS评分均低于常规组,差异均有统计学意义(P<0.05)。结论:对行VSD治疗的深度烧伤患者采用基于行动研究法的健康管理,可明显提高患者的疾病认知和伤残接受度,调节其负性情绪,利于创面外观恢复及生活质量提升,患者满意度较高,值得推荐。 展开更多
关键词 深度烧伤 行动研究法 健康管理 负压封闭引流技术 创面修复 美学效果
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银离子敷料联合复方多粘菌素B软膏治疗深Ⅱ度烧伤感染性创面的疗效观察
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作者 马雅宁 赵鹏 +3 位作者 孟素玉 徐文虎 胡荔男 王康 《中国美容医学》 CAS 2024年第4期25-29,共5页
目的:探讨银离子敷料联合复方多粘菌素B软膏治疗深Ⅱ度烧伤感染性创面的疗效。方法:选取149例深Ⅱ度烧伤感染性创面患者,依照乱数表法分为观察组(n=75例)和对照组(n=74例),对照组给予复方多粘菌素B软膏治疗,观察组在对照组基础上加用银... 目的:探讨银离子敷料联合复方多粘菌素B软膏治疗深Ⅱ度烧伤感染性创面的疗效。方法:选取149例深Ⅱ度烧伤感染性创面患者,依照乱数表法分为观察组(n=75例)和对照组(n=74例),对照组给予复方多粘菌素B软膏治疗,观察组在对照组基础上加用银离子敷料治疗。统计比较两组创面恢复相关指标、创面疼痛程度、血清炎性因子和疼痛介质水平、临床疗效及瘢痕情况。结果:治疗后,观察组感染控制时间、住院时间、创面愈合时间均短于对照组(P<0.05),治疗21 d后的创面愈合率高于对照组(P<0.05)。观察组治疗后各时间点疼痛评分均低于对照组(P<0.05);治疗21 d后,观察组血清C反应蛋白、白介素-6、神经肽Y、前列腺素E2水平均低于对照组(P<0.05),创面愈合总有效率高于对照组(P<0.05);创面愈合后6个月,观察组温哥华瘢痕量表各评分及总分均低于对照组(P<0.05)。结论:银离子敷料联合复方多粘菌素B软膏治疗深Ⅱ度烧伤感染性创面能促进创面愈合,减轻创面疼痛程度,并能有效抑制血清炎性因子、疼痛介质水平,减轻创面瘢痕程度,提升创面美学效果。 展开更多
关键词 银离子敷料 复方多粘菌素B软膏 深Ⅱ度烧伤感染性创面 炎性因子 瘢痕
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Consensus on the management of pediatric deep partial-thickness burn wounds(2023 edition)
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作者 Yan Liu Chinese Burn Association 《Burns & Trauma》 SCIE 2023年第1期828-841,共14页
Burns are a main cause of accidental injuries among children in China.Because of the unique wound repair capacity and demand for growth in pediatric patients,the management of pediatric deep partial-thickness burn wou... Burns are a main cause of accidental injuries among children in China.Because of the unique wound repair capacity and demand for growth in pediatric patients,the management of pediatric deep partial-thickness burn wounds involves a broader range of treatment options and controversy.We assembled experts from relevant fields in China to reach a consensus on the key points of thermal-induced pediatric deep partial-thickness burn-wound management,including definition and diagnosis,surgical treatments,nonsurgical treatment,choice of wound dressings,growth factor applications,infectious wound treatment,scar prevention and treatment.The committee members hope that the Expert Consensus will provide help and guiding recommendations for the treatment of pediatric deep partial-thickness burn wounds. 展开更多
关键词 deep partial sickness burns PEDIATRIC wound management Expert consensus
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改良自体中厚皮片对功能部位深度烧伤创面修复效果的影响
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作者 李瑞粦 黄永新 《中国医疗美容》 2024年第8期78-80,共3页
目的探讨功能部位深度烧伤患者采用改良自体中厚皮片对创面修复效果的影响。方法选取2022年1月至2024年1月莆田市第一医院烧伤科收治的功能部位深度烧伤患者共计50例,按照治疗方法的不同分成研究组(n=25)与对照组(n=25),对照组采用常规... 目的探讨功能部位深度烧伤患者采用改良自体中厚皮片对创面修复效果的影响。方法选取2022年1月至2024年1月莆田市第一医院烧伤科收治的功能部位深度烧伤患者共计50例,按照治疗方法的不同分成研究组(n=25)与对照组(n=25),对照组采用常规自体中厚皮片治疗,研究组采用改良自体中厚皮片治疗。比较两组创面愈合质量、创面愈合时间、住院时间、瘢痕情况。结果研究组创面愈合总优良率96.00%,高于对照组72.00%,差异有统计学意义(χ^(2)=5.357,P<0.05);研究组创面愈合(9.65±2.74)d、住院时间(11.47±2.77)d短于对照组(11.52±2.96)d、(13.83±3.12)d,差异有统计学意义(t值分别为2.318、2.828,P<0.05);研究组温哥华瘢痕量表评分(4.62±0.75)分低于对照组(5.41±1.02)分,差异有统计学意义(t=3.100,P<0.05)。结论功能部位深度烧伤患者采用改良自体中厚皮片治疗,能够提高创面愈合质量,缩短创面愈合、住院时间,改善瘢痕情况。 展开更多
关键词 功能部位深度烧伤 改良自体中厚皮片 创面修复
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负压创面治疗术辅助治疗深度烧伤的效果
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作者 王薇茗 陈立发 《医药前沿》 2024年第4期82-84,共3页
目的:探讨负压创面术在深度烧伤治疗中的辅助效果.方法:选取2021年10月—2023年4月在扬州大学附属医院接受治疗的63例深度烧伤患者作为研究对象,根据是否接受负压创面治疗术将患者分为观察组(n=30)和对照组(n=33).两组均行削痂植皮治疗... 目的:探讨负压创面术在深度烧伤治疗中的辅助效果.方法:选取2021年10月—2023年4月在扬州大学附属医院接受治疗的63例深度烧伤患者作为研究对象,根据是否接受负压创面治疗术将患者分为观察组(n=30)和对照组(n=33).两组均行削痂植皮治疗,观察组联用负压创面术,比较两组的治疗效果.结果:治疗后,观察组疼痛评分低于对照组,差异有统计学意义(P<0.05).治疗后,观察组的白细胞介素6、肿瘤坏死因子α和C反应蛋白水平均低于对照组,差异有统计学意义(P<0.05).观察组的创面愈合时间、肉芽生长时间和换药次数均低于对照组,差异有统计学意义(P<0.05).两组并发症发生率比较,差异无统计学意义(P>0.05).结论:在经削痂植皮术治疗深度烧伤的基础上联合采用负压创面术,能够更好改善患者的血清炎症因子水平,从而加快创面愈合. 展开更多
关键词 深度烧伤 负压创面治疗 炎症因子 创面愈合
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负压创面治疗技术配合削痂植皮术治疗深度烧伤的临床效果及安全性分析
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作者 姜吉波 韩晓春 《反射疗法与康复医学》 2024年第7期92-95,共4页
目的探讨负压创面技术联合削痂植皮术治疗深度烧伤患者的临床效果及安全性。方法选择2020年4月—2023年1月青岛市城阳区人民医院收治的70例深度烧伤患者为研究对象,按随机数字表法将其分为对照组与观察组,各35例。对照组采用削痂植皮术... 目的探讨负压创面技术联合削痂植皮术治疗深度烧伤患者的临床效果及安全性。方法选择2020年4月—2023年1月青岛市城阳区人民医院收治的70例深度烧伤患者为研究对象,按随机数字表法将其分为对照组与观察组,各35例。对照组采用削痂植皮术治疗,观察组在对照组基础上联合负压创面技术治疗,两组均连续治疗7 d。比较两组的创面愈合、疼痛程度、血清炎性因子及并发症发生情况。结果观察组创面愈合、肉芽生长时间均短于对照组,换药频次少于对照组,组间差异有统计学意义(P<0.05);治疗前,两组疼痛程度、血清炎性因子比较,组间差异无统计学意义(P<0.05);治疗后,观察组疼痛视觉模拟评分为(3.11±0.62)分,低于对照组的(5.21±0.54)分,差异有统计学意义(P<0.05);观察组肿瘤坏死因子-α、白细胞介素-6、C反应蛋白、白细胞计数水平均低于对照组,组间差异有统计学意义(P<0.05);观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论负压创面技术与削痂植皮术共同治疗浓度烧伤患者的效果更佳,可加快深度烧伤患者创面愈合速度,减轻其疼痛程度,降低炎症因子水平,且并发症较少,安全可靠。 展开更多
关键词 深度烧伤 负压创面 削痂植皮术 临床效果
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聚氨酯泡沫敷料联合磺胺嘧啶银霜对深Ⅱ度烧伤患者创面溶痂的影响 被引量:10
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作者 王之学 肖继州 +1 位作者 于强 杨书培 《长春中医药大学学报》 2023年第9期1043-1046,共4页
目的探究聚氨酯泡沫敷料联合磺胺嘧啶银霜对深Ⅱ度烧伤患者创面溶痂的影响。方法选取2019年5月-2022年5月于聊城市第二人民医院收治的深Ⅱ度烧伤患者80例,随机分为对照组(38例)和研究组(42例)。对照组使用磺胺嘧啶银霜进行治疗,研究组... 目的探究聚氨酯泡沫敷料联合磺胺嘧啶银霜对深Ⅱ度烧伤患者创面溶痂的影响。方法选取2019年5月-2022年5月于聊城市第二人民医院收治的深Ⅱ度烧伤患者80例,随机分为对照组(38例)和研究组(42例)。对照组使用磺胺嘧啶银霜进行治疗,研究组采取在对照组的基础上联合聚氨酯泡沫敷料予以治疗。检测2组完全溶痂的时间以及溶痂率、完全治愈的时间以及治愈率、炎症指标、不同时间段的视觉模拟评分法(VAS)评分、并发症发生情况的变化。结果与对照组相比,研究组完全溶痂的时间、完全治愈的时间、并发症总的发生率下降,T1、T2、T3的溶痂率以及T1、T2、T3的治愈率上升,且研究组较对照组情况改善更明显,差异具有统计学意义(P<0.05);治疗7 d后,2组的白介素-1(IL^(-1))、白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、不同时间段VAS评分有所下降,且研究组低于对照组,差异具有统计学意义(P<0.05)。结论通过聚氨酯泡沫敷料联合磺胺嘧啶银霜对于治疗深Ⅱ度烧伤患者效果明显,可有效提高患者的溶痂及治愈率,加快创面恢复,降低患者创面疼痛的程度。 展开更多
关键词 深Ⅱ度烧伤 聚氨酯泡沫敷料 磺胺嘧啶银霜 创面溶痂
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