Prevention and Treatment of Deep Vein Thrombosis of the Lower Limbs in Patients with Complications after Orthopedic Trauma Surgery

Objective:To explore and analyze on how to prevent and treat deep vein thrombosis of the lower limbs in patients with complications after orthopedic trauma surgery.Methods:The research patients were selected from the cases of surgical treatment of orthopedic trauma in the hospital during the past two years,and a total of 58 patients were selected.The patients were randomly divided into two groups,with 29 patients in the control group treated with conventional clinical methods;and the other 29 patients were assigned to the experimental group,where targeted preventive and therapeutic measures were administered.During the research,the number of complications of postoperative deep vein thrombosis of the lower limbs and the corresponding treatment efficacy were compared between the two groups of patients.Results:According to the results of clinical experiments,the probability of patients in the experimental group suffering from deep vein thrombosis of the lower limbs after surgery was significantly lower than that of the control group(P<0.05);in addition,when complications of deep venous thrombosis of the lower limbs occurred,the treatment efficacy of the patients in the experimental group was 96.55%,and the treatment efficacy of the patients in the control group was 82.76%.There was a significant difference between the two groups(P<0.05).Conclusion:Through clinical experiments to study and analyze the prevention and treatment measures of deep vein thrombosis in patients with complications after orthopedic trauma surgery,this research proves that active and comprehensive preventive and treatment measures can effectively reduce the number of complications and improve surgery treatment efficacy.

Establishment of a nomogram model for predicting therapy complications in patients with polycythemia and deep venous thrombosis

BACKGROUND Patients with deep venous thrombosis(DVT)residing at high altitudes can only rely on anticoagulation therapy,missing the optimal window for surgery or thrombolysis.Concurrently,under these conditions,patient outcomes can be easily complicated by high-altitude polycythemia(HAPC),which increases the difficulty of treatment and the risk of recurrent thrombosis.To prevent reaching this point,effective screening and targeted interventions are crucial.Thus,this study analyzes and provides a reference for the clinical prediction of thrombosis recurrence in patients with lower-extremity DVT combined with HAPC.AIM To apply the nomogram model in the evaluation of complications in patients with HAPC and DVT who underwent anticoagulation therapy.METHODS A total of 123 patients with HAPC complicated by lower-extremity DVT were followed up for 6-12 months and divided into recurrence and non-recurrence groups according to whether they experienced recurrence of lower-extremity DVT.Clinical data and laboratory indices were compared between the groups to determine the influencing factors of thrombosis recurrence in patients with lowerextremity DVT and HAPC.This study aimed to establish and verify the value of a nomogram model for predicting the risk of thrombus recurrence.RESULTS Logistic regression analysis showed that age,immobilization during follow-up,medication compliance,compliance with wearing elastic stockings,and peripheral blood D-dimer and fibrin degradation product levels were indepen-dent risk factors for thrombosis recurrence in patients with HAPC complicated by DVT.A Hosmer-Lemeshow goodness-of-fit test demonstrated that the nomogram model established based on the results of multivariate logistic regression analysis was effective in predicting the risk of thrombosis recurrence in patients with lowerextremity DVT complicated by HAPC(χ^(2)=0.873;P>0.05).The consistency index of the model was 0.802(95%CI:0.799-0.997),indicating its good accuracy and discrimination.CONCLUSION The column chart model for the personalized prediction of thrombotic recurrence risk has good application value in predicting thrombotic recurrence in patients with lower-limb DVT combined with HAPC after discharge.

Deep Venous Thrombosis: Commonly Affected Veins in the Lower Limbs

Aim and Objectives: This study aimed to record the commonly affected veins in the lower limbs, to compare the affected sides and gender and to correlate the Doppler findings and stages of deep venous thrombosis (DVT). Materials and Methods: A descriptive retrospective study of 46 already diagnosed cases of lower limb DVT. Results: Out of 46 cases of DVT, 71.74% were females. The majority of patients (93.47%) were affected in unilateral lower limb with significant predominance (65.22%) to affect the left lower limb (p Conclusion: Lower limb deep venous thrombosis affects left lower limb more than right and females more than males. Superficial femoral vein (SFV) and common femoral vein (CFV) are the most common affected veins. Lower limb DVT predominantly present in acute stage with venous distension and absent blood flow.

Pitfalls and sources of error of color duplex ultrasonography in detecting deep vein thrombosis of proximal lower extremities

Purpose To analyze the sources of errors and discuss the techniques to eliminate pitfalls in detecting deep vein thrombosis (DVT) of the proximal lower extremities with color duplex ultrasonography (CDUS). Methods Sixty-eight cases with initial and repeat venous CDUS of the proximal lower extremities were retrospectively reviewed. The repeat was done within 24 hours after initial CDUS scanning. Comparing repeated images to initial ones, the pitfalls and sources of error in CDUS of the proximal lower extremities were discussed. Results In total 68 repeat studies, there were 62 results as same as initials and 4 cases of false negative DVT and 2 cases of false positive DVT. Conclusion Venous CDUS in detecting DVT is observer dependent. Some pitfalls and errors can be eliminated and corrected with proper scan techniques. CDUS is the most valuable imaging modality for assessing suspected DVT in the proximal lower extremities.

Combined effect of Traditional Chinese Medicine decoction and low-molecular-weight heparin calcium on the postoperative deep venous thrombosis in patients with lower limb fracture

OBJECTIVE: To investigate the combined effect of Traditional Chinese Medicine(TCM) decoction and low-molecular-weight heparin calcium on deep vein thrombosis(DVT) induced by surgery in patients with lower limb fracture.METHODS: Totally 86 hospitalized patients with DVT after surgery of lower limb fracture between September 2012 and January 2015 were recruited and randomly divided into control group and observation group, 43 cases in each group. The patients in the control group were treated with subcutaneous injection of low-molecular-weight heparin calcium, and those in the observation group were additionally given Danshen Injection and TCM decoction. The differences between two groups in occurrence rate, medication time, therapeutic effects,recurrence rate of thrombosis, activated partial thromboplastin time(APTT), and prothrombin time(PT) were compared.RESULTS: The occurrence rate of DVT in observation group(4.65%, 2/43) was lower than that in control group(27.91%,12/43)(P<0.05). The medication time of observation group was(6.15±2.94) d, shorter than(9.76±3.12) d in the control group(P<0.05). In observation group, 2 cases of DVT were cured(2/2); in the control group, 9 cases presented therapeutic effects and the total effective rate was 75.00%(9/12). The improvement of APTT and PT in the observation group was better than that in the control group(P<0.05).CONCLUSION: Integrative TCM decoction plus low-molecularweight heparin calcium is superior to applicaton of low-molecularweight heparin calcium alone in reducing and treating DVT in the postoperative patients with lower limb fracture.

Preventing Lower Extremity Deep Vein Thrombosis After Hip Fracture Surgery in Elderly Patients by Acupoint Application Combined with Pneumatic Compression Therapy

Objective:To investigate and analyze the long-term clinical effects of acupoint application combined with pneumatic compression therapy in the prevention of deep venous thrombosis after hip fracture surgery among the elderly.Methods:Sixty elderly patients who had undergone hip fracture surgery from February 2021 to February 2022 were selected as the research subjects.The patients were divided into two groups via drawing lots.Both the groups received nursing care,but the patients in the observation group were treated with TCM acupoint application combined with pneumatic compression therapy,whereas the control group received pneumatic compression therapy.The evaluation indicators included the patients’quality of life and complications.Results:The incidence of lower extremity deep vein thrombosis in the observation group was more than twice(0.3%),whereas the incidence of lower extremity complications in the control group was more than 6 times(20%).There was a significant difference between the two groups(p<0.05).Conclusion:Traditional Chinese medicine acupoint application combined with pneumatic compression therapy is beneficial for the prevention of postoperative lower extremity deep vein thrombosis among elderly patients.In addition,the patients’overall quality-of-life scores in both physiological and psychological aspects improved significantly,which carries significant clinical reference value.

Deep Vein Thrombosis of the Upper Limb: About 6 Cases Collected in Dakar

Deep vein thrombosis of the upper limb is a rare location of venous thromboembolic disease. Data on this form of thrombosis are limited. We report six cases collected in Dakar. The sex ratio was 0.5 and the average age was 27.6 years with extremes of 17 and 39. Painful limb edema was the most constant sign and involved the non-dominant limb in almost all patients. Thrombosis occurred in a field of peripartum cardiomyopathy in two patients and SS sickle cell disease in one patient taking oral contraception. There was neither cancer nor venous catheter in medical history. The diagnosis was made by venous Doppler ultrasound in all patients. Subclavian involvement was the most common. The thrombophilia assessment, done for two patients, was normal. It was about exertion thrombosis on three (3) patients. All the patients had received antivitamin K treatment relaying a low molecular weight heparin. Venous limb compression was associated with anticoagulation for all patients. The treatment duration was six (6) months. There were no reports of pulmonary embolism or death. One patient presented a post-thrombotic syndrome.

Analysis of curative effect of Bingxiao powder on lower limb deep vein thrombosis

Objective:To investigate the therapeutic effect of Bingxiao powder on edema caused by deep venous thrombosis in lower limb thrombosis.Methods:Selected in our hospital from September 2017 to April 2019 of 122 patients with lower limb deep vein thrombosis caused by edema.The patients were divided into two groups:Bingxio powder(61 cases)and magnesium sulfate(61 cases),the circumference difference of lower leg and thigh,the integral of edema and pain,the effective rate and the satisfaction rate of curative effect were compared between the two groups of patients with edema caused by thrombosis of lower limb.Results:in the observation group,the peripheral diameter difference of calf(1.08±0.21)cm,the peripheral diameter difference of thigh(1.76±0.28),the edema score(1.09±0.22)and the pain score(1.34±0.25)were all lower than those of the control group(P<0.05).The effective rate(95.08%)and satisfaction rate(96.72%)of the observation group were higher than those of the control group(P<0.05).Conclusion:Bingxiao powder can reduce the edema symptoms and pain symptoms of patients with edema caused by deep venous thrombosis of lower limbs,and reduce the circumference difference of the lower leg and thigh,with significant clinical effect.

An Unwonted, Pedagogic Case Report on Effort Thrombosis of Right Brachial Vein

Deep vein thrombosis (DVT) is one or more blood clots formed inside the deep vein in the body resulting in complete or partial blockage of blood flow through the affected vein. Upper Extremity DVT (UEDVT) accounts for 5% - 10% of all cases of DVTs. Previously it was thought to be a rare disorder. However in recent years with the advent of various indwelling intravenous devices, hypercoagulable state like COVID-19, secondary UEDVT did not remain infrequent presentation anymore. Though primary UEDVT, also known as Effort Thrombosis, that takes place without any underlying obvious pathology is a rare form till now. We presented a case of 46 years female who presented to the emergency with complaints of progressively increasing pain (7 days) and swelling (3 days) of her right forearm since last 7 days following strenuous and heavy work by her dominant/ right hand during the period of festival. She initially ignored her condition because of the Durga Puja festival. As her symptoms deteriorated she eventually had to attend the emergency department. Eventually an urgent ultrasonography color Doppler was done on emergency basis which diagnosed underlying DVT of her right brachial vein. She was managed with low molecular weight heparin, urgent fasciotomy owning to her impending compartment syndrome. Other tests ruled out any secondary underlying pathology. She improved and discharged without any complications on oral anticoagulant. Exigent events in her history were trauma followed by fall on her right elbow 2 months back and then presenting signs & symptoms commencing at the same region following strenuous, tedious activities over 7 days and consequential effort thrombosis of her right brachial vein. All of that compelled us to ruminate on rare differentials of her presentation and eventually come to this rare diagnosis. The author hence brought this pedagogic case to the readers, especially emergency & primary care physicians and emphasised the importance of being intuitive about rare but deadly differentials which come from proficiency & experience in the field of medicine.

重症患者下肢深静脉血栓物理治疗的研究进展

重症患者病情较为复杂,治疗期间常出现下肢深静脉血栓(DVT),不利于其病情的恢复,虽常规药物防治效果较好,但极易引起患者出血。物理治疗可弥补药物治疗的不足,基于此,本研究针对重症患者下肢DVT的物理治疗展开综述,旨在为重症患者早期进行物理治疗预防下肢DVT提供参考依据。

多元化健康教育模式在预防下肢骨折患者深静脉血栓中的应用

目的探讨多元化健康教育模式在预防下肢骨折患者深静脉血栓中的应用效果。方法采用便利抽样法,选取2021年1~12月收治的下肢骨折患者300例,按照住院时间将2021年1~6月收治的患者作为对照组,将2021年7~12月收治的患者作为观察组,每组150例。对照组采用常规健康教育模式,观察组采用多元化健康教育模式。比较2组患者对深静脉血栓的认知水平、基本预防措施依从性、深静脉血栓的发生率,以及患者对护理工作满意度。结果观察组患者对深静脉血栓的认知水平、对基本预防措施的依从性、护理满意度显著高于对照组(P<0.05)。观察组患者深静脉血栓发生率为16.00%低于对照组的25.33%,差异有统计学意义(P<0.05)。结论将多元化健康教育模式应用于下肢骨折患者,可提高护理效果,降低深静脉血栓的发生率,值得推广应用。

脑卒中恢复期患者下肢深静脉血栓风险预测模型的构建及应用

目的探究脑卒中恢复期患者下肢深静脉血栓(deep vein thrombosis,DVT)的发生率及其影响因素,构建此类患者DVT风险预测模型。方法采用回顾性研究设计,选取收治的脑卒中恢复期患者431例,通过单因素和多因素logistic回归分析筛选出DVT发生的影响因素,构建风险预测模型并用列线图展示,应用受试者工作特征(ROC)曲线下面积、敏感度、特异度评价模型的预测效果,使用Bootstrap法对模型进行内部验证。结果431例患者中,有36例发生DVT,发生率为8.35%,建模组301例患者有26例发生DVT,发生率为8.64%,验证组130例患者有10例发生DVT,发生率为7.69%。Logistic回归分析显示MBI积分、Caprini血栓风险因素总分、平均血小板体积(MPV)、肌酐(Cr)、凝血酶时间(TT)、D-二聚体(D-Dimer)是脑卒中恢复期患者发生DVT的独立影响因素(OR值分别为0.978、1.186、0.662、0.979、1.043、1.766,均P<0.1)。以该6个因素为自变量构建列线图,建模组AUC为0.842,约登指数最大值为0.525,诊断值为0.115,敏感度为0.833,特异度为0.692;Hosmer-Lemeshow拟合优度检验2=7.458,P=0.589。验证组AUC为0.720,约登指数最大值为0.425,诊断值为0.072,敏感度为0.675,特异度为0.700,Hosmer-Lemeshow拟合优度检验2=11.414,P=0.248。结论脑卒中恢复期患者DVT发生率较高,MBI积分、Caprini血栓风险因素总分、MPV、Cr、TT、D-Dimer是其重要的影响因素,构建的列线图可个性化预测脑卒中恢复期患者DVT发生风险,有助于医护人员制订相应的干预措施。

基于诺莫图构建髋部骨折患者发生下肢深静脉血栓的预测模型

目的探讨髋部骨折患者发生下肢深静脉血栓(DVT)的独立危险因素,并构建和验证列线图模型。方法选择2020年1月至2023年6月佛山市中医院骨科收治的髋部骨折患者227例为研究对象,按照7∶3比例将患者分为建模组(n=159)和验证组(n=68)。收集患者的临床资料,采用LASSO回归和Logistic回归筛选髋部骨折患者发生DVT的独立危险因素,建立风险预测模型和列线图。采用一致性指数(C-index)、校准曲线、受试者工作特征(ROC)曲线进行评价。结果建模组159例髋部骨折中发生DVT 33例,发生率为20.89%。LASSO回归结合多因素Logistic回归分析结果显示,年龄≥70岁、糖尿病、受伤至手术时间≥5 d、低蛋白血症、D-二聚体>0.5是髋部骨折患者发生DVT的独立危险因素。基于上述危险因素绘制列线图模型,将上述5个危险因素构建列线图模型,模型区分度良好(C-index=0.932);Hosmer-Lemeshow检验显示,列线图的拟合优度良好(χ^(2)=57.625,P=0.732)。建模组和验证组发生DVT的ROC曲线下面积分别为0.932、0.821,模型准确度高。结论年龄≥70岁、糖尿病、受伤至手术时间≥5 d、低蛋白血症、D-二聚体>0.5是髋部骨折患者发生DVT的独立危险因素,基于上述因子构建的列线图模型可有效预测髋部骨折患者发生DVT的风险。

基于Caprini量表评估干预措施结合空气波压力治疗仪对乳腺癌术后患者下肢深静脉血栓形成的影响

目的探讨基于Caprini量表评估干预措施结合空气波压力治疗仪对乳腺癌术后患者下肢深静脉血栓(DVT)形成的影响。方法选取2020年3月至2023年9月合肥市第二人民医院收治的80例乳腺癌术后患者,按照入院时间分为两组。入院时间2020年3月至2022年3月为常规组,入院时间2022年4月至2023年9月为干预组,各40例。常规组行基于Caprini量表评估预防护理,干预组在常规组的基础上实施空气波压力治疗仪干预。观察两组DVT发生率,比较两组干预前后世界卫生组织生存质量测定量表简表评分及满意度。结果干预组术后下肢DVT发生率低于常规组,差异有统计学意义(P<0.05)。干预前,两组生理领域、心理领域、环境领域、社会关系领域评分比较,差异无统计学意义(P>0.05);干预后,两组生理领域、心理领域、环境领域、社会关系领域评分高于干预前,且干预组高于常规组,差异有统计学意义(P<0.05)。干预组护理满意度优于常规组,差异有统计学意义(P<0.05)。结论乳腺癌患者术后实施基于Caprini量表评估干预措施结合空气波压力治疗仪干预,可明显提高下肢DVT预防效果,降低下肢DVT发生率,提高生活质量及满意度高。

中医护理预防髋关节置换术后下肢深静脉血栓的Meta分析

目的系统评价髋关节置换术后中医护理预防下肢深静脉血栓形成的临床效果。方法计算机检索PubMed、国家知识基础设施数据库(CNKI)、维普资讯中文期刊服务平台(VIP)、万方学术期刊全文数据库(Wanfang)中关于髋关节置换术后中医护理预防下肢深静脉血栓形成的文献,检索时间为2012—2022年11月。采用Cochrane干预措施系统评价手册(5.1.0版)偏倚风险评估工具对纳入的随机对照研究进行质量评价,运用RevMan5.4软件对纳入文献进行Meta分析。结果纳入11项研究,涉及1087例患者,其中研究组597例,对照组508例。Meta分析结果显示:中医护理下肢深静脉血栓发生率低于常规护理[RR=0.18,95%CI(0.09~0.35),Z=5.03,P<0.00001]。中医护理髋关节置换术后患者纤维蛋白原降低程度较常规护理明显[MD=-0.47,95%CI(-0.77~-0.16),Z=2.96,P=0.003],差异有统计学意义(P<0.05)。中医护理凝血酶原时间[MD=1.86,95%CI(-1.64~5.36),Z=1.04,P=0.30]、活化部分凝血活酶时间[MD=3.77,95%CI(-1.84~9.38),Z=1.32,P=0.19]与常规护理比较差异无统计学意义(P>0.05)。结论研究结果表明,髋关节置换术后,中医护理对预防下肢深静脉血栓形成有一定效果,且能显著降低纤维蛋白原,但在改善凝血酶原时间和活化部分凝血活酶时间方面,其效果与常规护理相比差异无统计学意义,受纳入范围和纳入研究质量的影响,上述结论尚待更多高质量的试验予以证实。

集束化护理对防治脑出血术后下肢深静脉血栓及缓解负性情绪的应用效果分析

目的:探讨集束化护理在预防脑出血术后患者下肢深静脉栓塞及缓解负性情绪方面的应用效果,为临床护理提供依据。方法:选取2018年11月—2020年3月广西医科大学第一附属医院收治的118例脑出血患者作为研究对象,根据入院的先后顺序将其分为对照组和实验组,每组各59例。对照组患者采用常规护理,实验组患者在常规护理基础上实施集束化护理干预。比较两组患者下肢深静脉血栓发生率、心理状态[焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分]、D-二聚体水平及护理满意度情况。结果:实验组患者下肢深静脉血栓发生率明显低于对照组,差异有统计学意义(χ^(2)=4.867,P<0.05)。干预后,实验组患者SAS评分、SDS评分均明显低于对照组,差异有统计学意义(t=4.985、5.012,P<0.05)。干预后,实验组患者D-二聚体水平明显低于对照组,差异有统计学意义(t=4.586,P<0.05)。实验组患者护理满意度明显高于对照组,差异有统计学意义(χ^(2)=8.768,P<0.05)。结论:对脑出血术后患者实施集束化护理干预,可预防患者下肢深静脉血栓,改善患者负性情绪,降低D-二聚体浓度,提高患者护理满意度。

足底静脉泵对肿瘤化疗患者住院期间下肢深静脉血栓的预防价值

目的探讨足底静脉泵对肿瘤化疗患者住院期间下肢深静脉血栓(DVT)的预防价值。方法收集2021年2月至2023年1月于亳州市人民医院住院接受化疗的128例恶性肿瘤患者的临床资料,根据住院期间是否接受了足底静脉泵干预将患者分为干预组(n=67)和对照组(n=61)。比较两组患者住院期间主要治疗信息、住院期间结局指标。结果两组患者各种治疗方案的使用比例比较,差异均无统计学意义(P﹥0.05)。住院期间,干预组患者下肢DVT的发生率和D-二聚体水平均低于对照组患者,差异均有统计学意义(P﹤0.05)。两组患者的凝血酶原时间、活化部分凝血活酶时间、消化道症状及白细胞计数减少的发生率比较,差异均无统计学意义(P﹥0.05)。干预组患者未发生足底静脉泵治疗相关并发症。结论足底静脉泵可有效降低肿瘤化疗患者住院期间发生下肢DVT的风险,且不会出现明显的治疗相关并发症,对患者的凝血功能无明显影响,值得临床推广。

改良冰肌散联合气压疗法预防股骨骨折下肢深静脉血栓临床观察

目的探究改良冰肌散联合气压疗法预防股骨骨折下肢深静脉血栓(LDVT)的临床疗效。方法采用回顾性观察性研究,选取2019年1月—2020年6月江西中医药大学附属医院骨科收治的股骨骨折患者60例。其中对照组30例行冰肌散涂药治疗,研究组30例行冰肌散涂药联合气压治疗。比较两组患者LDVT的发生率、疼痛视觉模拟量表(VAS)评分、下肢肿胀的变化及不良反应发生率。结果与对照组比较,研究组患者LDVT的发生率、下肢肿胀发生率及VAS评分均显著降低(P<0.05)。研究组治疗总有效率为93.33%(28/30),高于对照组的80.00%(24/30)(P<0.05)。两组患者治疗期间均未出现不良反应。结论改良冰肌散联合气压疗法预防股骨骨折LDVT的临床显著。

高龄产妇剖宫产术后住院期间下肢深静脉血栓形成预测模型构建

目的:分析高龄产妇剖宫产术后住院期间下肢深静脉血栓形成(LEDVT)的影响因素,并构建Nomogram。方法:选择2021年1月-2023年10月到本院接受剖宫产术的202例高龄产妇临床资料,依据其术后住院期间有无发生LEDVT分为发生组(n=51)与未发生组(n=151),logistic回归分析筛选高龄产妇剖宫产术后住院期间LEDVT的危险因素;用R软件绘制预测高龄产妇剖宫产术后住院期间LEDVT的Nomogram,且用受试者工作特征(ROC)曲线、校准曲线、Hosmer-Lemeshow拟合优度检验评估。结果:202例发生LEDVT51例,占25.3%。logistic回归分析显示,口服避孕药史(95%CI1.847~9.183,P=0.001)、血栓史(95%CI1.336~5.512,P=0.006)、妊娠高血压疾病(95%CI1.391~7.302,P=0.006)、妊娠期糖尿病(95%CI1.059~5.257,P=0.036)是高龄产妇剖宫产术后住院期间LEDVT的独立危险因素。ROC曲线下面积0.763(95%CI0.693~0.833)。校准曲线斜率接近1,且Hosmer-Lemeshow拟合优度检验χ^(2)=5.911,P=0.315。结论:高龄产妇剖宫产术后住院期间LEDVT发生受口服避孕药史、血栓史、妊娠高血压疾病及妊娠期糖尿病的影响,依此构建的Nomogram可预测高龄产妇剖宫产术后住院期间LEDVT发生风险,为LEDVT的早期预警、及早预防、临床诊疗提供依据。

踝泵运动联合穴位贴敷对长期卧床患者下肢血流动力学的影响

目的探究踝泵运动联合穴位贴敷疗法对长期卧床患者下肢血流动力学的影响。方法选取江西中医药大学附属医院2022年1月—2022年12月收治的120例患者根据时间先后顺序,分成对照组和观察组,各60例。对照组采用常规护理,观察组在对照组基础上给予踝泵运动联合穴位贴敷,观察2组下肢深静脉血栓(DVT)发生率、股静脉血流峰(tVmax)、血流平均速度(Vm)、凝血功能指标及患者预防DVT的知识、态度及行为。结果干预后,观察组DVT发生率低于对照组;观察组tVmax、Vm、凝血功能指标均优于对照组;观察组预防DVT的知识、态度评分、遵医依从率及生活质量评分高于对照组,差异均有统计学意义(P<0.05)。结论踝泵运动联合穴位贴敷能改善长期卧床患者的下肢血流动力学情况,预防DVT,值得应用。