期刊文献+

二次检索

题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息
共找到3,302篇文章
< 1 2 166 >
每页显示 20 50 100
Efficacy of percutaneous mechanical thrombus removal in acute lower extremity deep venous thrombosis
1
作者 Jun-Qiang Xue Ping Yin +3 位作者 Jian-Ping He Hui Wei Cui-Jie Geng Yu-Xian Luo 《World Journal of Clinical Cases》 SCIE 2024年第21期4590-4600,共11页
BACKGROUND Acute lower extremity deep venous thrombosis(LEDVT)is a common vascular emergency with significant morbidity risks,including post-thrombotic syndrome(PTS)and pulmonary embolism.Traditional treatments like c... BACKGROUND Acute lower extremity deep venous thrombosis(LEDVT)is a common vascular emergency with significant morbidity risks,including post-thrombotic syndrome(PTS)and pulmonary embolism.Traditional treatments like catheter-directed thrombolysis(CDT)often result in variable success rates and complications.AIM To investigate the therapeutic efficacy of percutaneous mechanical thrombus removal in acute LEDVT.METHODS A retrospective analysis was performed to examine 58 hospitalised patients with acute LEDVT between August 2019 and August 2022.The patients were categorised into the percutaneous mechanical thrombectomy(PMT)group(n=24)and CDT group(n=32).The follow-up,safety and treatment outcomes were compared between the two groups.The main observational indexes were venous patency score,thrombus removal effect,complications,hospitalisation duration and PTS.RESULTS The venous patency score was 9.04±1.40 in the PMT group and 8.81±1.60 in the CDT group,and the thrombus clearance rate was 100%in both groups.The complication rate was 8.33%in the PMT group and 34.84%in the CDT group,and the difference was statistically significant(P<0.05).The average hospitalisation duration was 6.54±2.48 days in the PMT group and 8.14±3.56 days in the CDT group.The incidence of PTS was lower in the PMT group than in the CDT group;however,the difference was not statistically significant(P<0.05).CONCLUSION Compared with CDT,treatment of LEDVT via PMT was associated with a better thrombus clearance rate,clinical therapeutic effect and PTS prevention function,but the difference was not statistically significant.Moreover,PMT was associated with a reduced urokinase dosage,shortened hospitalisation duration and reduced incidence of complications,such as infections and small haemorrhages.These results indicate that PMT has substantial beneficial effects in the treatment of LEDVT. 展开更多
关键词 Post-thrombotic syndrome Catheter-directed thrombolysis Percutaneous mechanical thrombectomy Acute lower extremity deep venous thrombosis
下载PDF
Clinical Value of Predictive Nursing Intervention on Deep Venous Thrombosis of Lower Extremities after Cesarean Section
2
作者 Xiaole LI 《Medicinal Plant》 2024年第4期73-76,共4页
[Objectives]To explore the clinical nursing value of predictive nursing intervention in patients with deep venous thrombosis of lower extremities after cesarean section.[Methods]From December 2022 to April 2023,105 pr... [Objectives]To explore the clinical nursing value of predictive nursing intervention in patients with deep venous thrombosis of lower extremities after cesarean section.[Methods]From December 2022 to April 2023,105 pregnant and lying-in women who were hospitalized in the Gynecology Department of Pingquan Hospital and underwent cesarean section and met the inclusion criteria were included as the study objects.According to the medical records,they were divided into observation group(n=52 cases)and control group(n=53 cases).The clinical experimental subjects were divided into two groups.One group was the control group with routine nursing,and the other group was the observation group with predictive nursing intervention.The number of cases of deep venous thrombosis of lower extremities in the two groups was recorded to evaluate the clinical value.[Results]The incidence of deep venous thrombosis of lower extremities in the two groups after cesarean section was compared,and it was suggested that the incidence of the observation group was lower than that of the control group(P<0.05).[Conclusions]Special predictive nursing intervention can greatly reduce the incidence of deep venous thrombosis of lower extremities after cesarean section,improve nursing satisfaction,and improve clinical efficacy,which is worthy of recommendation. 展开更多
关键词 Predictive nursing intervention Cesarean section deep venous thrombosis of lower extremities Clinical value
下载PDF
Manual aspiration thrombectomy for acute and subacute inferior vena cava thrombosis and lower extremity deep venous thrombosis 被引量:17
3
作者 Janesya Sutedjo Yan Li Jianping Gu 《Journal of Interventional Medicine》 2018年第4期197-204,共8页
Deep vein thrombosis(DVT), which can lead to pulmonary embolism(PE), is a major contributor to the global disease burden and is the third most common cardiovascular pathology after coronary artery disease and stroke. ... Deep vein thrombosis(DVT), which can lead to pulmonary embolism(PE), is a major contributor to the global disease burden and is the third most common cardiovascular pathology after coronary artery disease and stroke. Venous thromboembolic disease, which encompasses the disease entities of DVT and PE, affects up to 10 million cases every year and represents a serious and potentially life-threatening condition. Standard anticoagulation therapy alone is ineffective at promoting deep venous system thrombus removal. Many patients develop postthrombotic syndrome(PTS) despite being on adequate anticoagulation therapy. Aggressive therapy for rapid thrombus removal is important to prevent the development of PTS. Besides impeding the onset of PTS, rapid clearance of the thrombus is also required in the treatment of phlegmasia cerulea dolens, an uncommon but life-threatening complication of acute DVT that can lead to arterial insufficiency, compartment syndrome, venous gangrene, and limb amputation. Manual aspiration thrombectomy(MAT) can provide rapid and effective therapy that could be compared to the open surgical thrombectomy approach with minimal risk of morbidity, mortality, or recurrence after surgery. Though many devices have been developed to date for pharmacomechanical thrombolysis, the cost of the treatment using these devices is very expensive. MAT is simple to perform, easy to learn, inexpensive, and rapid. This review will outline and dissect several studies and case reports, sourced from the Pub Med database, on the subject of the use of MAT in treating inferior vena cava thrombosis and lower extremity DVT, including in patients with compression of the iliac vein and phlegmasia cerulea dolens. 展开更多
关键词 THROMBECTOMY venous thrombosis lower extremity vena cava INFERIOR
下载PDF
Two-point compression ultrasonography: Enough to rule out lower extremity deep venous thrombosis? 被引量:2
4
作者 Ralphe Bou Chebl Nader El Souki +3 位作者 Mirabelle Geha Imad Majzoub Rima Kaddoura Hady Zgheib 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2021年第4期268-273,共6页
BACKGROUND: Deep venous thrombosis(DVT) is a major cause of morbidity and is a common presenting complaint to the emergency department(ED). Point-of-care two-point compression ultrasonography has evolved as a quick an... BACKGROUND: Deep venous thrombosis(DVT) is a major cause of morbidity and is a common presenting complaint to the emergency department(ED). Point-of-care two-point compression ultrasonography has evolved as a quick and effective way of diagnosing DVT. The purpose of this study is to validate the prevalence and distribution of venous thrombi isolated to proximal lower extremity veins, other than common femoral and popliteal veins in patients with DVT.METHODS: This is a single-center retrospective study that looked at patients presenting to the ED of a tertiary care hospital between January 2014 and August 2018. The clinical presentation and laboratory and imaging results were obtained using the hospital's electronic medical record.RESULTS: A total of 2,507 patients underwent a lower extremity duplex ultrasound during the study period. Among them, 379(15%) were included in the study. The percentages of isolated thrombi to the femoral vein and deep femoral vein were 7.92% and 0.53%, respectively. When the patients were stratified into the two groups of isolated DVT and two-point compression DVT, there were no statistically significant differences in the laboratory results between both groups. However, immobilized patients and patients with recent surgeries were more likely to have an isolated DVT.CONCLUSIONS: Thrombi isolated to proximal lower extremity veins other than the common femoral and popliteal veins make up 8.45% of DVTs. Given this significant number of missed DVTs, the authors recommend the addition of the femoral and deep femoral veins to the two-point compression exam. 展开更多
关键词 lower extremity deep venous thrombosis Emergency department Two-point compression ultrasonography
下载PDF
Clinical Application of Percutaneous Transluminal Angioplasty and Stent Implantation in Acute Lower Extremity Deep Venous Thrombosis
5
作者 Lei Zhang 《Journal of Advances in Medicine Science》 2018年第4期129-132,共4页
Purpose: To analyze the application of percutaneous transluminal angioplasty and stenting in acute deep venous thrombosis of lower extremities. Methods: 70 patients were divided into two groups according to the presen... Purpose: To analyze the application of percutaneous transluminal angioplasty and stenting in acute deep venous thrombosis of lower extremities. Methods: 70 patients were divided into two groups according to the presence or absence of percutaneous transluminal angioplasty and stenting. Results: The mean circumferential diameter difference between the affected limbs and the healthy limbs and the knees at 15 cm was statistically significant. The cure rate and effective rate of the research group were higher than those of the control group (P<0.05). Conclusion: Percutaneous transluminal angioplasty and stenting are of high value in acute lower extremity deep venous thrombosis. 展开更多
关键词 PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY Stent implantation Acute deep venous thrombosis of lower extremity Clinical application
下载PDF
Discussion on Prevention and Treatment of Lower Extremity Deep Venous Thrombosis in Orthopedic Perioperative Period from Spleen and Stomach Meridians
6
作者 Jinlu Wang Qiang Zan Sirui Xie 《Journal of Clinical and Nursing Research》 2021年第1期82-89,共8页
Deep venous thrombosis of lower extremity is one of the common complications in orthopedic perioperative period.It is caused by many factors,such as peripheral vein dilation,slow blood flow;long-term immobilization,be... Deep venous thrombosis of lower extremity is one of the common complications in orthopedic perioperative period.It is caused by many factors,such as peripheral vein dilation,slow blood flow;long-term immobilization,bed rest and so on.On the one hand,it affects the early postoperative functional exercise and functional recovery,on the other hand,it increases the length of hospital stay and economic burden,increases the pain of patients and even endangers their lives.Effective treatment of traditional Chinese medicine combined with western medicine can play a better role in the prevention and treatment of lower extremity deep venous thrombosis.This study expounds the concept of spleen and stomach meridians in the prevention and treatment of lower extremity deep venous thrombosis,and puts forward some opinions on the dialectical treatment and daily conditioning of lower extremity deep venous thrombosis,hoping to provide ideas for the clinical prevention and treatment of lower extremity deep venous thrombosis in traditional Chinese medicine. 展开更多
关键词 lower extremity deep venous thrombosis Stomach meridian Spleen meridian
下载PDF
Establishment of a nomogram model for predicting therapy complications in patients with polycythemia and deep venous thrombosis
7
作者 Ming-Xian Zhao Guo-Jie Li 《World Journal of Clinical Cases》 SCIE 2024年第22期4881-4889,共9页
BACKGROUND Patients with deep venous thrombosis(DVT)residing at high altitudes can only rely on anticoagulation therapy,missing the optimal window for surgery or thrombolysis.Concurrently,under these conditions,patien... BACKGROUND Patients with deep venous thrombosis(DVT)residing at high altitudes can only rely on anticoagulation therapy,missing the optimal window for surgery or thrombolysis.Concurrently,under these conditions,patient outcomes can be easily complicated by high-altitude polycythemia(HAPC),which increases the difficulty of treatment and the risk of recurrent thrombosis.To prevent reaching this point,effective screening and targeted interventions are crucial.Thus,this study analyzes and provides a reference for the clinical prediction of thrombosis recurrence in patients with lower-extremity DVT combined with HAPC.AIM To apply the nomogram model in the evaluation of complications in patients with HAPC and DVT who underwent anticoagulation therapy.METHODS A total of 123 patients with HAPC complicated by lower-extremity DVT were followed up for 6-12 months and divided into recurrence and non-recurrence groups according to whether they experienced recurrence of lower-extremity DVT.Clinical data and laboratory indices were compared between the groups to determine the influencing factors of thrombosis recurrence in patients with lowerextremity DVT and HAPC.This study aimed to establish and verify the value of a nomogram model for predicting the risk of thrombus recurrence.RESULTS Logistic regression analysis showed that age,immobilization during follow-up,medication compliance,compliance with wearing elastic stockings,and peripheral blood D-dimer and fibrin degradation product levels were indepen-dent risk factors for thrombosis recurrence in patients with HAPC complicated by DVT.A Hosmer-Lemeshow goodness-of-fit test demonstrated that the nomogram model established based on the results of multivariate logistic regression analysis was effective in predicting the risk of thrombosis recurrence in patients with lowerextremity DVT complicated by HAPC(χ^(2)=0.873;P>0.05).The consistency index of the model was 0.802(95%CI:0.799-0.997),indicating its good accuracy and discrimination.CONCLUSION The column chart model for the personalized prediction of thrombotic recurrence risk has good application value in predicting thrombotic recurrence in patients with lower-limb DVT combined with HAPC after discharge. 展开更多
关键词 Anticoagulation therapy deep vein thrombosis of the lower extremities High-altitude polycythemia Logistic regression analysis Nomogram model thrombosis recurrence
下载PDF
Deep Venous Thrombosis: Commonly Affected Veins in the Lower Limbs 被引量:1
8
作者 Sultan Abdulwadoud Alshoabi Abdullatif Mothanna 《Journal of Biosciences and Medicines》 2019年第3期12-19,共8页
Aim and Objectives: This study aimed to record the commonly affected veins in the lower limbs, to compare the affected sides and gender and to correlate the Doppler findings and stages of deep venous thrombosis (DVT).... Aim and Objectives: This study aimed to record the commonly affected veins in the lower limbs, to compare the affected sides and gender and to correlate the Doppler findings and stages of deep venous thrombosis (DVT). Materials and Methods: A descriptive retrospective study of 46 already diagnosed cases of lower limb DVT. Results: Out of 46 cases of DVT, 71.74% were females. The majority of patients (93.47%) were affected in unilateral lower limb with significant predominance (65.22%) to affect the left lower limb (p Conclusion: Lower limb deep venous thrombosis affects left lower limb more than right and females more than males. Superficial femoral vein (SFV) and common femoral vein (CFV) are the most common affected veins. Lower limb DVT predominantly present in acute stage with venous distension and absent blood flow. 展开更多
关键词 Common LOCATIONS deep venous thrombosis (dvt) lower LIMBS
下载PDF
Comparison of four clinical scores for the predicting lower limb deep venous thrombosis in Chinese patients 被引量:1
9
作者 Li Zhu Min Liu +5 位作者 Xiaojuan Guo Jianguo Wang Youmin Guo Chen Wang Hongxia Ma Yulin Guo 《Journal of Nanjing Medical University》 2008年第4期230-233,共4页
Objective:To evaluate Wells, Kahn, St.Andr 6 and Constans scores for the prediction of deep venous thrombosis in Chinese patients. Methods:One hundred and seventy-two patients, prospectively, blinded referred for ev... Objective:To evaluate Wells, Kahn, St.Andr 6 and Constans scores for the prediction of deep venous thrombosis in Chinese patients. Methods:One hundred and seventy-two patients, prospectively, blinded referred for evaluation with four clinical-score systems for suspected deep venous thrombosis, were examined by ultrasonography. Sensitivity, specificity, positive predictive value, negative predictive value and receiver operation curves were calculated for four clinical scores. The difference between areas of the ROC curve for each of the scores was compared with others and reference line. Results:Forty-six of 172 patients had deep venous thrombosis proven by sonography. The sensitivity, specificity, positive predictive value and negative predictive value for Wells score was 91.3%, 57.1%, 43.8% and 94.7%, respectively, for Kahn score; 65.2%, 71.4%, 45.5% and 84.9%, respectively, for St.Andr 6 score; 63%, 38.9%, 27.4% and 74.2% respectively, for Constans score; 95.7%, 34.9%, 34.9% and 95.7% respectively. Area under ROV curve of Constans score was 0.814, which was similar to that of Wells score, then followed by Kahn score and that of St.Andr 6 score was no difference with the reference line. Conclusion:Based on the results of our study, the sensitivity, negative prediction value and area under ROC curve are larger for Constans score and Wells score in Chinese hospitalized patients than that of Kahn score or St.Andr 6 score. Considering the aim of the clinical assessment, Constans score and Wells score are more efficient for Chinese hospitalized patients. 展开更多
关键词 deep venous thrombosis clinical assessment lower extremity sonography
下载PDF
Preventing Lower Extremity Deep Vein Thrombosis After Hip Fracture Surgery in Elderly Patients by Acupoint Application Combined with Pneumatic Compression Therapy 被引量:2
10
作者 Xing Fu Yan Cheng 《Proceedings of Anticancer Research》 2022年第2期6-9,共4页
Objective:To investigate and analyze the long-term clinical effects of acupoint application combined with pneumatic compression therapy in the prevention of deep venous thrombosis after hip fracture surgery among the ... Objective:To investigate and analyze the long-term clinical effects of acupoint application combined with pneumatic compression therapy in the prevention of deep venous thrombosis after hip fracture surgery among the elderly.Methods:Sixty elderly patients who had undergone hip fracture surgery from February 2021 to February 2022 were selected as the research subjects.The patients were divided into two groups via drawing lots.Both the groups received nursing care,but the patients in the observation group were treated with TCM acupoint application combined with pneumatic compression therapy,whereas the control group received pneumatic compression therapy.The evaluation indicators included the patients’quality of life and complications.Results:The incidence of lower extremity deep vein thrombosis in the observation group was more than twice(0.3%),whereas the incidence of lower extremity complications in the control group was more than 6 times(20%).There was a significant difference between the two groups(p<0.05).Conclusion:Traditional Chinese medicine acupoint application combined with pneumatic compression therapy is beneficial for the prevention of postoperative lower extremity deep vein thrombosis among elderly patients.In addition,the patients’overall quality-of-life scores in both physiological and psychological aspects improved significantly,which carries significant clinical reference value. 展开更多
关键词 Acupoint application Traditional Chinese medicine Pneumatic compression therapy Minimally invasive surgery for hip fracture in elderly patients lower extremity deep vein thrombosis
下载PDF
Predictive Value of Systemic Immune Inflammation Index, Aggregate Index of Systemic Inflammation, and Systemic Inflammation Response Index in Lower Extremity Deep Venous Thrombosis Following Severe Trauma
11
作者 Peng-Fei Li Xin Lu +4 位作者 Yu-Qian Zhou Ke Wang Peng Yang Xiong-Hui Chen Feng Xu 《Chinese Medical Sciences Journal》 CAS 2024年第4期241-248,共8页
Objective Venous thromboembolism is a highly prevalent condition after polytrauma,and recognized as an important factor contributing to poor prognosis.The aim of this study was to investigate the risk factors for lowe... Objective Venous thromboembolism is a highly prevalent condition after polytrauma,and recognized as an important factor contributing to poor prognosis.The aim of this study was to investigate the risk factors for lower extremity deep venous thrombosis(LEDVT)in a severely traumatized population and to evaluate their predictive value for LEDVT.Methods This was a retrospective,single-center observational study.All subjects were severely traumatized patients who were admitted to the Traumatic Intensive Care Unit from January 2021 to May 2024.Based on Doppler ultrasound findings of both lower extremities from the time of injury to 30 days post-injury,patients who developed LEDVT were enrolled in the LEDVT group,and those who did not develop LEDVT were enrolled in the NLEDVT group.Demographic,clinical,and laboratory data were collected upon admission.Multivariable logistic regression analysis was performed to identify risk factors for LEDVT.Receiver operating characteristic(ROC)curve was used to evaluate the overall fit of the final model.Results There were 56 patients enrolled in the LEDVT group and 81 patients in the NLEDVT group.Age,Aggregate Index of Systemic Inflammation(AISI),Systemic Inflammation Response Index(SIRI),ICU length of stay,and albumin were identified as independent risk factors for LEDVT(all P<0.05).The area under their ROC curves were 0.604,0.657,0.694,0.668,and 0.405,respectively.Combined model for early clinical prediction of LEDVT in severely traumatized patients by age,SIRI,AISI,and albumin resulted in an area under the ROC curve of 0.805(95%CI:0.73-0.88,SE=0.037).Conclusion The combination of age,SIRI,AISI,and albumin has a predictive value for LEDVT in severely traumatized patients. 展开更多
关键词 severe trauma Systemtic Immune Inflammation Index Aggregate Index of Systemic Inflammation Systemic Inflammation Response Index lower extremity deep venous thrombosis
下载PDF
Pitfalls and sources of error of color duplex ultrasonography in detecting deep vein thrombosis of proximal lower extremities 被引量:3
12
作者 GAO Jing YI Lian-hua Auh Yong Ho 《中国医学影像技术》 CSCD 2004年第3期472-476,共5页
Purpose To analyze the sources of errors and discuss the techniques to eliminate pitfalls in detecting deep vein thrombosis (DVT) of the proximal lower extremities with color duplex ultrasonography (CDUS). Methods Six... Purpose To analyze the sources of errors and discuss the techniques to eliminate pitfalls in detecting deep vein thrombosis (DVT) of the proximal lower extremities with color duplex ultrasonography (CDUS). Methods Sixty-eight cases with initial and repeat venous CDUS of the proximal lower extremities were retrospectively reviewed. The repeat was done within 24 hours after initial CDUS scanning. Comparing repeated images to initial ones, the pitfalls and sources of error in CDUS of the proximal lower extremities were discussed. Results In total 68 repeat studies, there were 62 results as same as initials and 4 cases of false negative DVT and 2 cases of false positive DVT. Conclusion Venous CDUS in detecting DVT is observer dependent. Some pitfalls and errors can be eliminated and corrected with proper scan techniques. CDUS is the most valuable imaging modality for assessing suspected DVT in the proximal lower extremities. 展开更多
关键词 深静脉血栓 静脉造影 彩色多普勒 伪影 影像学诊断 质量控制
下载PDF
Analysis thrombolysis with anticoagulation treatment for early stage of deep vein thrombosis in the lower extremities
13
作者 刘心 张梅 +2 位作者 刘陕西 祈光裕 刘亚民 《Journal of Medical Colleges of PLA(China)》 CAS 2003年第2期99-101,共3页
Objective: To explore the effect of thrombolysis with anticoagulation treatment for early stage of deep vein thrombosis of lower extremity. Methods: The clinical data of 106 patients at the early stage of deep vein th... Objective: To explore the effect of thrombolysis with anticoagulation treatment for early stage of deep vein thrombosis of lower extremity. Methods: The clinical data of 106 patients at the early stage of deep vein thrombosis (DVT) in the lower extremities treated by thrombolysis with anticoagulation and dispersion drugs were analyzed retrospectively. Results: The thrombolytic effect was significant. After treatment, the deep veins were recanalized without regurgitation in 75.3% of the patients. The total effective rate was 100%. Only three patients had hemorrhagic complication, but none of the patients died. Conclusion: Thrombolysis with anticoagulation treatment is an effective and safe method for DVT at the early stage. 展开更多
关键词 deep venous thrombosis lower extremity vena anticoagulation treatment
下载PDF
Analysis of curative effect of Bingxiao powder on lower limb deep vein thrombosis
14
作者 Xia Zhai Jing Dong Guo-Rong Deng 《History & Philosophy of Medicine》 2020年第2期28-32,共5页
Objective:To investigate the therapeutic effect of Bingxiao powder on edema caused by deep venous thrombosis in lower limb thrombosis.Methods:Selected in our hospital from September 2017 to April 2019 of 122 patients ... Objective:To investigate the therapeutic effect of Bingxiao powder on edema caused by deep venous thrombosis in lower limb thrombosis.Methods:Selected in our hospital from September 2017 to April 2019 of 122 patients with lower limb deep vein thrombosis caused by edema.The patients were divided into two groups:Bingxio powder(61 cases)and magnesium sulfate(61 cases),the circumference difference of lower leg and thigh,the integral of edema and pain,the effective rate and the satisfaction rate of curative effect were compared between the two groups of patients with edema caused by thrombosis of lower limb.Results:in the observation group,the peripheral diameter difference of calf(1.08±0.21)cm,the peripheral diameter difference of thigh(1.76±0.28),the edema score(1.09±0.22)and the pain score(1.34±0.25)were all lower than those of the control group(P<0.05).The effective rate(95.08%)and satisfaction rate(96.72%)of the observation group were higher than those of the control group(P<0.05).Conclusion:Bingxiao powder can reduce the edema symptoms and pain symptoms of patients with edema caused by deep venous thrombosis of lower limbs,and reduce the circumference difference of the lower leg and thigh,with significant clinical effect. 展开更多
关键词 EDEMA deep venous thrombosis of the lower LIMB Bingxiao POWDER
下载PDF
下肢动脉硬化闭塞病人介入术后并发DVT的风险预测列线图模型构建及验证
15
作者 刘要先 李博 +1 位作者 孟杨海 邓飞 《安徽医药》 CAS 2024年第1期100-104,共5页
目的探讨下肢动脉硬化闭塞病人介入术后并发深静脉血栓(DVT)的风险因素,并构建DVT风险预测列线图模型及进行验证。方法回顾性分析2018年6月至2022年5月在漯河市中心医院进行经皮腔内介入术治疗的374例下肢动脉硬化闭塞病人的临床资料,... 目的探讨下肢动脉硬化闭塞病人介入术后并发深静脉血栓(DVT)的风险因素,并构建DVT风险预测列线图模型及进行验证。方法回顾性分析2018年6月至2022年5月在漯河市中心医院进行经皮腔内介入术治疗的374例下肢动脉硬化闭塞病人的临床资料,根据术后是否并发DVT而将病人分为并发DVT组与未并发DVT组。对比两组一般资料,采用多因素logistic回归分析法分析下肢动脉硬化闭塞介入术后并发DVT的危险因素,并利用R软件与rms程序构建DVT风险预测列线图模型,且应用caret程序包通过Bootstrap法对其进行内部验证,计算模型一致性指数(C-index),并绘制受试者操作特征(ROC)曲线评价该模型的预测效能。结果374例下肢动脉硬化闭塞病人介入术后3个月内,DVT并发率为9.63%(36/374);并发DVT组年龄≥60岁占比、完全闭塞占比、术后卧床时间≥3 d占比及总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDLC)、纤维蛋白原(FIB)、D-二聚体(D-D)、血小板计数(PLT)均高于未并发DVT组[69.44%(25/36)比50.59%(171/338)、41.67%(15/36)比25.44%(86/338)、58.33%(21/36)比22.19%(75/338)、(4.96±1.02)mmol/L比(4.63±0.94)mmol/L、(2.09±0.26)mmol/L比(1.81±0.31)mmol/L、(3.65±0.54)mmol/L比(3.47±0.51)mmol/L、(3.45±0.62)g/L比(3.11±0.54)g/L、(0.67±0.11)mg/L比(0.38±0.06)mg/L、(246.85±42.74)×10^(9)/L比(205.16±39.68)×10^(9)/L](P<0.05),凝血酶时间(TT)低于未并发DVT组[(15.16±3.11)s比(16.33±3.14)s](P<0.05);多因素logistic回归分析结果显示年龄≥60岁、术后卧床时间≥3 d、TG、FIB、D-D、PLT均是下肢动脉硬化闭塞介入术后并发DVT的危险因素(P<0.05);基于多因素logistic回归分析结果而构建下肢动脉硬化闭塞介入术后并发DVT的风险预测列线图模型,其校正曲线结果显示标准曲线与校准预测曲线具有良好的贴合度;该模型C-index为0.88(0.81~0.89),ROC曲线下面积为0.85[95%CI:(0.78,0.91),Z=9.54,P<0.001]。结论基于年龄、术后卧床时间、TG、FIB、D-D、PLT构建的下肢动脉硬化闭塞病人介入术后并发DVT风险预测列线图模型具有较好的预测能力与区分能力,对临床筛选高风险人群具有较高的指导价值。 展开更多
关键词 血管成形术 手术后并发症 静脉血栓形成 闭塞性动脉硬化 下肢 风险因素 列线图模型
下载PDF
椎管内麻醉与全身麻醉下手术的下肢骨折老年患者LDVT发生率比较
16
作者 许哲 李灿 《深圳中西医结合杂志》 2024年第1期26-29,共4页
目的:比较椎管内麻醉与全身麻醉下手术对下肢骨折老年患者下肢深静脉血栓(LDVT)发生率的影响。方法:选取2020年1月至2022年1月在永城市人民医院接受手术治疗的90例下肢骨折老年患者,依据随机数字表将全部患者均分为对照组(全身麻醉)与... 目的:比较椎管内麻醉与全身麻醉下手术对下肢骨折老年患者下肢深静脉血栓(LDVT)发生率的影响。方法:选取2020年1月至2022年1月在永城市人民医院接受手术治疗的90例下肢骨折老年患者,依据随机数字表将全部患者均分为对照组(全身麻醉)与观察组(椎管内麻醉),各45例。比较两组患者手术情况、术后恢复情况、麻醉情况、术中生命体征、术后48 h运动功能状态,统计术后LDVT与麻醉并发症发生率。结果:观察组患者手术时间、术中出血量、术后床旁活动时间及住院时间均少于对照组,差异具有统计学意义(P<0.05);观察组患者麻醉生效时间、术后睁眼时间、语言陈述恢复时间、术中麻醉药物用量均少于对照组,差异具有统计学意义(P<0.05);观察组患者麻醉后10 min(T1)、术毕即刻(T2)时心率、平均动脉压均低于对照组,差异具有统计学意义(P<0.05);观察组患者术后48 h的运动功能分级优于对照组,差异具有统计学意义(Z=2.183,P<0.05);观察组患者术后LDVT发生率与麻醉不良反应总发生率均低于对照组,差异具有统计学意义(P<0.05)。结论:椎管内麻醉与全身麻醉相比,能够有效降低下肢骨折老年患者术后LDVT发生风险。 展开更多
关键词 下肢骨折 椎管内麻醉 全身麻醉 下肢深静脉血栓 老年人
下载PDF
The Use of Low Molecular Weight Heparin for Venous Thromboembolism Prophylaxis in Medical Patients: How Much Are We Adherent to the Guidelines? 被引量:1
17
作者 Lamia AlHajri Nicole Gebran 《Open Journal of Internal Medicine》 2015年第4期81-91,共11页
Background: Venous thromboembolism (VTE) is a common complication seen during or after hospitalization that manifests as deep venous thrombosis (DVT) and/or pulmonary embolism (PE). PE is considered the commonest prev... Background: Venous thromboembolism (VTE) is a common complication seen during or after hospitalization that manifests as deep venous thrombosis (DVT) and/or pulmonary embolism (PE). PE is considered the commonest preventable cause of death during and/or after hospitalization. Thus, pharmacological and mechanical methods are used to prevent VTE in hospitalized patients. Despite the availability of guidelines for VTE prophylaxis, it is crucial to assess the adherence and adaptation of the institution to these guidelines. Purpose: This study aimed to investigate adherence to the American College of Chest Physicians (ACCP) 2012 VTE prophylaxis guidelines in hospitalized medical patients in a tertiary care hospital in the United Arab Emirates. Methods: An observational prospective design was utilized in this study. To achieve the purpose, primary and secondary end points were identified to be the core of the investigation. The primary end points were: the incidence of bleeding, VTE, and cardiovascular events. While the secondary end points were: dose and indication validity for prophylaxis, VTE and bleeding risk assessments, adverse drug events (ADE) other than bleeding, appropriate monitoring when on low molecular weight heparin (LMWH) and the presence of contraindication at the time of prescribing LMWH. Results: 16 patients (20%) out of the total 80 met one or more of the primary end points. The vast majority of patients (81.25%) developed bleeding, while VTE was seen in one case only during hospitalization. 11 patients (13.75%) received LMWH while a contraindication was present. 15 patients (18.75%) who were prescribed LMWH had an International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) bleeding risk score of ≥7. However, 5 out of 13 patients (38.46%) who developed bleeding had a bleeding score of ≥7, and the relationship between bleeding score of ≥7 and the development of bleeding was statistically significant (p = 0.047). When investigating the doses that were utilized, 40% were prescribed an inappropriate dose. Conclusion: Various factors played a role in the inappropriateness of VTE prophylaxis such as;poor adherence to VTE guidelines, inappropriate dosing and monitoring, and not evaluating the bleeding risk. Hence, to be able to achieve effective VTE prophylaxis, these factors need to be addressed through adherence to and adaptation of the ACCP 2012 VTE prophylaxis guidelines. 展开更多
关键词 venous THROMBOEMBOLISM (VTE) deep venous thrombosis (dvt) Pulmonary EMBOLISM (PE) VTE PROPHYLAXIS GUIDELINES International Medical Prevention Registry on venous THROMBOEMBOLISM (IMPROVE) Padua Risk Assessment Score
下载PDF
前置胎盘剖宫产术后下肢DVT风险诺莫图模型的建立与验证
18
作者 张全华 管文莉 +2 位作者 郭芳 徐雪 任艳芳 《海南医学》 CAS 2024年第20期2949-2954,共6页
目的探讨前置胎盘(PP)剖宫产术后下肢深静脉血栓(DVT)的影响因素,基于影响因素构建诺莫图模型并给予验证。方法回顾性分析2018年1月至2023年5月新乡医学院第一附属医院收治的300例PP患者的临床资料,依据术后患者是否出现下肢DVT分为DVT... 目的探讨前置胎盘(PP)剖宫产术后下肢深静脉血栓(DVT)的影响因素,基于影响因素构建诺莫图模型并给予验证。方法回顾性分析2018年1月至2023年5月新乡医学院第一附属医院收治的300例PP患者的临床资料,依据术后患者是否出现下肢DVT分为DVT组50例和无DVT组250例。采用单因素、多因素筛选术后下肢DVT影响因素,采用R语言构建诺莫图模型,绘制受试者工作特征(ROC)曲线及曲线下面积(AUC),采用校准曲线、决策曲线(DCA)对该模型进行内部验证。另选取2023年5~12月50例符合条件的PP患者进行外部验证。结果DVT组和无DVT组患者在PP类型、妊娠期糖尿病、胎盘残留、胎膜早破及可溶性CD40配体(sCD40L)、趋化配体3(CCL3)、D-二聚体(D-D)、纤维蛋白原(FIB)水平方面比较差异均有统计学意义(P<0.05);多因素Logistic分析结果显示,妊娠糖尿病(OR=3.684,95%CI:1.341~10.118)、FIB(OR=1.592,95%CI:1.236~2.051)、D-D(OR=1.409,95%CI:1.001~1.982)、s CD40L(OR=1.626,95%CI:1.115~2.371)、CCL3(OR=1.707,95%CI:1.142~2.553)均是PP剖宫产术后患者下肢DVT发生的影响因素(P<0.05);构建诺莫图模型,该模型预测PP剖宫产术后患者下肢DVT的AUC为0.794(95%CI:0.720~0.868),预测概率与实际概率高度重合,接近1,在0.1~0.9范围内,模型获益率具有临床实用价值;外部验证结果显示,诺莫图模型在外部验证中AUC为0.851(95%CI:0.761~0.940),校准曲线趋于理想曲线,且净获益均高于两条极端曲线。结论妊娠期糖尿病、FIB、D-D、s CD40L、CCL3是PP剖宫产术后下肢DVT发生的独立影响因素,构建诺莫图模型对术后下肢DVT具有良好预测价值及临床正向净获益,临床可加强预测模型应用。 展开更多
关键词 前置胎盘 下肢深静脉血栓 影响因素 诺莫图模型 预测
下载PDF
股骨颈骨折内固定术后并发下肢DVT的风险预测列线图构建及预防护理建议 被引量:2
19
作者 刘芳 侯喜燕 《全科护理》 2024年第5期905-909,共5页
目的:构建股骨颈骨折(FNF)病人内固定术后并发下肢深静脉血栓(DVT)的风险预测列线图,并提出预防护理建议。方法:回顾性分析2018年7月—2022年1月在医院进行内固定术治疗的264例FNF病人的临床资料,按照病人术后住院期间是否并发下肢DVT... 目的:构建股骨颈骨折(FNF)病人内固定术后并发下肢深静脉血栓(DVT)的风险预测列线图,并提出预防护理建议。方法:回顾性分析2018年7月—2022年1月在医院进行内固定术治疗的264例FNF病人的临床资料,按照病人术后住院期间是否并发下肢DVT分为并发组(40例)与未并发组(224例)。采用Logistic回归分析法筛选FNF病人内固定术后并发下肢DVT的独立危险因素,并据此构建风险预测列线图模型。采用Bootstrap自抽样法与一致性指数(C-index)评价预测模型的符合度,通过校准曲线与受试者工作特征(ROC)曲线评价模型的精准度与区分度。结果:并发组的年龄、入院时血小板计数、术中失血量及体质指数(BMI)>24 kg/m^(2)、Garden分型为Ⅲ/Ⅳ型、合并心脑血管疾病、入院时血清白蛋白水平<35 g/L、入院时D-二聚体水平>0.5 mg/L、受伤至手术的时间≥3 d、切开复位、使用止血带、术后隐性失血、术后卧床时间≥5 d的病人占比均高于未并发组(P<0.05)。Logistic回归分析显示,年龄大、入院时血清白蛋白水平<35 g/L、入院时血小板计数高、入院时D-二聚体水平>0.5 mg/L、受伤至手术的时间≥3 d、切开复位、术后卧床时间≥5 d均是FNF病人内固定术后并发下肢DVT的独立危险因素(P<0.05)。FNF病人内固定术后并发下肢DVT的列线图模型的校准曲线与理想曲线贴合良好,C-index为0.825,ROC曲线下面积为0.832[95%CI(0.781,0.875)],列线图具有良好的预测效能。结论:年龄、入院时血清白蛋白水平、血小板计数、D-二聚体水平、受伤至手术的时间、复位方式、术后卧床时间均是FNF病人内固定术后并发下肢DVT的独立影响因素,据此建立的列线图模型对FNF病人内固定术后并发下肢DVT风险的预测效能良好。 展开更多
关键词 股骨颈骨折 内固定术 下肢深静脉血栓 列线图模型 影响因素
下载PDF
血浆D-D、凝血因子、PC变化与乳腺癌根治术后发生DVT的多因素研究 被引量:1
20
作者 罗小克 徐艳平 陈小艳 《湖北民族大学学报(医学版)》 2024年第1期72-75,共4页
目的探讨血浆D-二聚体(D-D)、凝血因子、血浆蛋白C(PC)与乳腺癌根治术后发生下肢深静脉血栓(DVT)的关系。方法选取接受乳腺癌根治术治疗且术后发生DVT的患者45例作为病例组,同期接受乳腺癌根治术未发生DVT的患者90例作为对照组;统计并... 目的探讨血浆D-二聚体(D-D)、凝血因子、血浆蛋白C(PC)与乳腺癌根治术后发生下肢深静脉血栓(DVT)的关系。方法选取接受乳腺癌根治术治疗且术后发生DVT的患者45例作为病例组,同期接受乳腺癌根治术未发生DVT的患者90例作为对照组;统计并分析两组的年龄、体质量指数(BMI)、乳腺癌病理学类型、肿瘤淋巴结转移分期(TNM)、辅助化疗、合并疾病情况、红细胞(RBC)、纤维蛋白原(FIB)、凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、凝血酶时间(TT)、D-D、凝血因子Ⅷ(FⅧ)、血浆PC的水平,并采用向前Logistic回归分析法分析D-D、FⅧ、血浆PC与乳腺癌根治术后发生DVT的关系。结果两组年龄、体质量指数(BMI)、患侧分布、病理学类型、TNM分期、高血压、糖尿病、RBC、TT水平比较,差异无统计学意义(P>0.05),病例组的辅助性化疗患者占比、FIB水平均高于对照组,PT、APTT水平均低于对照组(P<0.05);病例组D-D、FⅧ水平高于对照组(P<0.05);病例组血浆PC水平低于对照组(P<0.05);Logistic回归模型结果显示FIB增高、D-D升高、FⅧ水平升高及APTT水平降低是乳腺癌根治术术后发生DVT的独立危险因素(OR=1.602,2.042,2.134,1.430,P<0.05)。结论引起乳腺癌术后发生DVT的因素众多,D-D、FⅧ水平升高会显著的增高乳腺癌根治术后发生DVT的风险。 展开更多
关键词 D-二聚体 凝血因子 蛋白C 乳腺癌根治术 下肢深静脉血栓
下载PDF
上一页 1 2 166 下一页 到第
使用帮助 返回顶部