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Potential contribution of pedicle screw design to loosening rate in patients with degenerative diseases of the lumbar spine:An observational study 被引量:1
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作者 Andrey Bokov Svetlana Pavlova +2 位作者 Anatoliy Bulkin Alexandr Aleynik Sergey Mlyavykh 《World Journal of Orthopedics》 2021年第5期310-319,共10页
BACKGROUND The majority of published data report the results of biomechanical tests of various design pedicle screw performance.The clinical relevance and relative contribution of screw design to instrumentation stabi... BACKGROUND The majority of published data report the results of biomechanical tests of various design pedicle screw performance.The clinical relevance and relative contribution of screw design to instrumentation stability have been insufficiently studied.AIM To estimate the contribution of screw design to rate of pedicle screw loosening in patients with degenerative diseases of the lumbar spine.METHODS This study is a prospective evaluation of 175 patients with degenerative diseases and instability of the lumbar spine segments.Participants underwent spinal instrumentation employing pedicle screws with posterior only or transforaminal interbody fusion.Follow-up was for 18 mo.Patients with signs of pedicle screw loosening on computed tomography were registered;logistic regression analysis was used to identify the factors that influenced the rate of loosening.RESULTS Parameters included in the analysis were screw geometry,type of thread,external and internal screw diameter and helical pitch,bone density in Hounsfield units,number of levels fused,instrumentation without anterior support,laminectomy,and unilateral and bilateral total facet joint resection.The rate of screw loosening decreased with the increment in outer diameter,decrease in core diameter and helical pitch.The rate of screw loosening correlated positively with the number of fused levels and decreasing bone density.Bilateral facet joint removal significantly favored pedicle screw loosening.The influence of other factors was insignificant.CONCLUSION Screw parameters had a significant impact on the loosening rate along with bone quality characteristics,the number of levels fused and the extensiveness of decompression.The significance of the influence of screw parameters was comparable to those of patient-and surgery-related factors.Pedicle screw loosening was influenced by helical pitch,inner and outer diameter,but screw geometry and thread type were insignificant factors. 展开更多
关键词 degenerative diseases lumbar spine Pedicle screw design Pedicle screw loosening
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Imaging of Degenerative Pathologies of the Lumbar Spine: Professional Habits in Some Hospitals in Cameroon
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作者 Mohamadou Aminou Yannick Onana Richard +4 位作者 Mbozo’o Nvondo Samuel Neossi Nguena Mathurin Aissata Bintou Moctar Ngo Nyemeg Celenaie Claude Mbo Amvene Jeremie 《Journal of Biosciences and Medicines》 2021年第8期143-154,共12页
<strong>Background:</strong> The lumbar spine is the portion most frequently involved in degenerative pathologies. Everyone will suffer one day from “low back pain”. These pathologies are very frequent: ... <strong>Background:</strong> The lumbar spine is the portion most frequently involved in degenerative pathologies. Everyone will suffer one day from “low back pain”. These pathologies are very frequent: epidemiological studies have shown that 65% to 90% of the general population could be affected by low back pain (lumbago) which could become chronic at acertain stage or could be complicated (2% to 4%) of cases could end up affecting nerve roots. Chronic low back pain causes a major public health problem in terms of morbidity and socioeconomic repercussions. <strong>Purpose:</strong> The overall purpose of this study is to evaluate the professional habits of exam applicants in case of degenerative pathologies of the lumbar spine, to Appreciate the knowledge of clinicians on the usefulness of medical imaging techniques in the event of suspicion of a degenerative pathology of the lumbar spine and finally to evaluate if the professional habits of requesting examinations in Cameroon comply with the Recommendations for Clinical Practice. <strong>Methods:</strong> A cross-sectional and descriptive study was used and was based on questionnaires distributed to those practitioners who requested for these diagnostic medical imaging studies and procedures at Yaoundé General Hospital (HGY), Yaoundé Central Hospital, La Cathédrale Medical Center, Yaoundé University Teaching Hospital, the Douala General Hospital, the Laquintinie Hospital of Douala, the Military Hospital of Douala, the Daniel Muna Memorial Clinic of Douala, the International Center for Clinical and Medicine Imaging, the Ngaoundere Regional Hospital and the Protestant Hospital of Ngaoundere (HPN), from April 2020 to March 2021. Data collected was processed and analyzed via Epi Info version 12.0 and the statistical test used for correlation was Chi2. <strong>Results:</strong> 137 practitioners were retained among whom, 90 were male and 47 females, their average age being 46 years with working experience less than 5 years (35.8%). The results obtained show that parameters such as availability and accessibility of the required diagnostic medical imaging modalities could greatly influence the examination prescription. On the contrary, few prescribers were less interested in the costs and secondary effects due to irradiation and the invasiveness of these examinations. Professional habits of those who requested these examinations were in majority closer in line with the recommended clinical practices. However, an average of 43.78% of prescribers never followed recommendations nor applied them. On the other hand, knowledge and the application of these recommendations increased as the prescriber’s working experience too increased. Up to 54.47% of prescribers were not aware of those recommendations about requesting these examinations. Conclusion: Our results indicate that Medical Diagnostic Imaging techniques are not judiciously and optimally exploited in the diagnosis of degenerative pathologies of the lumbar spine and it would be necessary to establish recommendations for clinical practice adapted to Cameroonian realities. 展开更多
关键词 lumbar spine Medical Imaging degenerative Pathologies Professional Habits RECOMMENDATIONS
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Minimally invasive procedures on the lumbar spine 被引量:8
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作者 Branko Skovrlj Jeffrey Gilligan +1 位作者 Holt S Cutler Sheeraz A Qureshi 《World Journal of Clinical Cases》 SCIE 2015年第1期1-9,共9页
Degenerative disease of the lumbar spine is a common and increasingly prevalent condition that is often implicated as the primary reason for chronic low back pain and the leading cause of disability in the western wor... Degenerative disease of the lumbar spine is a common and increasingly prevalent condition that is often implicated as the primary reason for chronic low back pain and the leading cause of disability in the western world. Surgical management of lumbar degenerative disease has historically been approached by way of open surgical procedures aimed at decompressing and/or stabilizing the lumbar spine. Advances in technology andsurgical instrumentation have led to minimally invasive surgical techniques being developed and increasingly used in the treatment of lumbar degenerative disease. Compared to the traditional open spine surgery, minimally invasive techniques require smaller incisions and decrease approach-related morbidity by avoiding muscle crush injury by self-retaining retractors, preventing the disruption of tendon attachment sites of important muscles at the spinous processes, using known anatomic neurovascular and muscle planes, and minimizing collateral soft-tissue injury by limiting the width of the surgical corridor. The theoretical benefits of minimally invasive surgery over traditional open surgery include reduced blood loss, decreased postoperative pain and narcotics use, shorter hospital length of stay, faster recover and quicker return to work and normal activity. This paper describes the different minimally invasive techniques that are currently available for the treatment of degenerative disease of the lumbar spine. 展开更多
关键词 Minimally invasive SURGERY spine SURGERY lumbar spine degenerative disease inTERBODY FUSION POSTEROLATERAL FUSION DECOMPRESSION indirect DECOMPRESSION techniques
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Central plasticity resulting from chronic low back pain in degenerative disorders of the spine 被引量:1
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作者 Michael Luchtmann Raimund Firsching 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第8期1234-1236,共3页
Degenerative disorders of the spine are the most common cause of chronic low back pain(c LBP);in Western Europe alone,billions of euros are spent each year on both conservative and surgical treatments for c LBP.And ... Degenerative disorders of the spine are the most common cause of chronic low back pain(c LBP);in Western Europe alone,billions of euros are spent each year on both conservative and surgical treatments for c LBP.And though only 5%of all patients with low back pain suffer from lumbar disc herniation(LDH), 展开更多
关键词 spine herniation degenerative suffer plasticity lumbar conservative alone alterations cortical
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Application of Finite Element Analysis in Biomechanical Research of Degenerative Diseases of Lumbar Spine
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作者 Shuyu Zhang Tianyi Bai +3 位作者 Xingxu Zhang Chao Feng Zhengpeng Liu Yilong Zhang 《Journal of Biosciences and Medicines》 2022年第3期21-33,共13页
As the elderly population continues to grow, the number of patients with low back pain is gradually increasing. Among them, Lumbar Degenerative Diseases (LDD) is one of the major contributors to low back pain. Biomech... As the elderly population continues to grow, the number of patients with low back pain is gradually increasing. Among them, Lumbar Degenerative Diseases (LDD) is one of the major contributors to low back pain. Biomechanical in vivo studies of the lumbar spine are mainly performed by implants or imaging data to record the real-time changes of form and stress on the intervertebral disc during motion. However, the current developments are slow due to the technological and ethical limitations. In vitro experiments include animal experiments and cadaver experiments, which are difficult to operate or differ greatly from normal human structures, and the results still need to be verified repeatedly to test their accuracy. As for finite element method, it is relatively low cost and can repeat the experimental results. Therefore, we believe that finite element analysis plays an extremely important role in biomechanical research, especially in analyzing the relationship between different surgical models and the degeneration caused by different mechanics. 展开更多
关键词 BIOMECHANICS degenerative Diseases of the lumbar spine Animal Specimens Human Cadaver Models Finite Element Analysis Statics Analysis STRESS Range of Motion (RoM)
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Retrospective Case Series of Porous Titanium Cages in Oblique Lumbar Interbody Fusion Surgery Assessing Subsidence, Fusion and Functional Outcomes
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作者 Joseph Maalouly Raghad Barri John Choi 《Open Journal of Orthopedics》 2023年第4期147-156,共10页
Purpose: Implant subsidence is a possible complication of spinal interbody fusion. We aim to evaluate porous titanium cages subsidence, fusion and functional outcomes in patients subjected to oblique lumbar interbody ... Purpose: Implant subsidence is a possible complication of spinal interbody fusion. We aim to evaluate porous titanium cages subsidence, fusion and functional outcomes in patients subjected to oblique lumbar interbody fusion (OLIF) with these novel devices. Methods: Our institutional review board approved a single-center experience which included 60 patients who underwent OLIF from June 2018 to June 2020 utilizing the porous titanium implants. Data was collected in accordance with the Declaration of Helsinki, and written informed consent was obtained. Imaging studies including radiographs 1, 3, 6 and 12 months and computed tomography (CT) scan at 6 months obtained during routine postoperative follow-up visits, were studied for signs of implant subsidence, fusion and clinical parameters to determine the effectiveness of surgery such as Oswestry disability index (ODI). Results: Radiographic subsidence occurred in 1 out of 89 porous titanium interbody cages (1.1%). No subsidence was observed in the posterior screws and rods fixation group (N = 57). However, one case of subsidence occurred in the lateral plate fixation group (N = 3). The subsidence occurred in an osteoporotic elderly patient operated for adjacent segment disease, and she was later revised with posterior instrumentation using cemented screws and rods. She had an uneventful recovery. Fusion rates were evaluated under CT scan at 6 months with a rate of 88%. In terms of clinical outcomes, ODI decreased significantly from 20.3 preop to 10.7 postop with a P-value Conclusions: In our study, the subsidence rate was lower than previously reported in the literature. Also, we had good fusion rates at 6 months likely due to the porous titanium cages use. We had no subsidence in the posterior instrumented group and one case in the lateral fixation group with improved clinical outcomes. 展开更多
关键词 degenerative Diseases OSTEOARTHRITIS lumbar spine Anterior-to-Psoas Oblique lumbar interbody Fusion
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Spectrum of magnetic resonance imaging findings in congenital lumbar spinal stenosis 被引量:2
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作者 Theodoros Soldatos Majid Chalian +4 位作者 Shrey Thawait Alan J Belzberg John Eng John A Carrino Avneesh Chhabra 《World Journal of Clinical Cases》 SCIE 2014年第12期883-887,共5页
AIM: To investigate whether congenital lumbar spinal stenosis(CLSS) is associated with a specific degenerative changes of the lumbar spine. METHODS: The lumbar spine magnetic resonance imaging studies of 52 subjects w... AIM: To investigate whether congenital lumbar spinal stenosis(CLSS) is associated with a specific degenerative changes of the lumbar spine. METHODS: The lumbar spine magnetic resonance imaging studies of 52 subjects with CLSS and 48 control subjects were retrospectively evaluated. In each examination, the five lumbar levels were assessed for the presence or absence of circumferential or shallow annular bulges, annular tears, anterior or posterior disc herniations, epidural lipomatosis, Schmorl's nodes,spondylolisthesis, pars defects, and stress reactions of the posterior vertebral elements. RESULTS: Compared to control individuals, subjects with CLSS exhibited increased incidence of circumferential and shallow annular bulges, annular tears, discherniations and spondylolisthesis(P < 0.05). CONCLUSION: CLSS is associated with increased incidence of degenerative changes in specific osseous and soft-tissue elements of the lumbar spine. 展开更多
关键词 CONGENITAL lumbar SPinAL STENOSIS Magnetic resonance IMAGinG IMAGinG findings degenerative changes Low back pain
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Quadrant通道下单侧后路腰椎椎体间融合术与传统开放术治疗退行性腰椎疾病的疗效比较
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作者 李剑 《中国医药指南》 2024年第16期19-21,共3页
目的 探讨Quadrant通道下单侧后路腰椎椎体间融合术与传统开放术治疗退行性腰椎疾病的价值。方法 选取2019年1月至2023年6月我院外科治疗的退行性腰椎疾病患者100例,通过随机数字表法分为两组。观察组(50例)实施Quadrant通道下单侧后路... 目的 探讨Quadrant通道下单侧后路腰椎椎体间融合术与传统开放术治疗退行性腰椎疾病的价值。方法 选取2019年1月至2023年6月我院外科治疗的退行性腰椎疾病患者100例,通过随机数字表法分为两组。观察组(50例)实施Quadrant通道下单侧后路腰椎椎体间融合术进行治疗,对照组(50例)实施常规开放手术治疗,比较两组治疗效果。结果 相比较对照组,观察组手术时间长、切口长度短、术中出血量小、术后引流量小、术后下地时间短、术后住院时间短(P <0.05),术后1、2、3d的疼痛评分低(P <0.05),术后2、4、6周的Oswestry功能障碍指数低(P <0.05),末次随访MacNab分级的优良率高(P <0.05)。结论 Quadrant通道下单侧后路腰椎椎体间融合术治疗退行性腰椎疾病效果十分显著,术后疼痛少,恢复快,术后功能障碍改善良好,具有较好的应用价值。 展开更多
关键词 退行性腰椎疾病 微创手术 椎体间融合术 功能障碍
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腰椎Modic改变与终板缺损体积和形态的联系及二者与腰痛相关性的研究
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作者 施能超 宋昊 +3 位作者 曹录民 刘栋 王啸 华俊 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2024年第7期711-718,共8页
目的:分析腰椎Modic改变的体积与终板缺损的体积、形态的相关性,探究相关终板病变与腰痛症状的联系。方法:回顾性分析2020年10月~2023年10月于苏州大学附属第二医院行腰椎MRI检查有终板缺损的401例患者的临床及影像资料,根据是否合并Mo... 目的:分析腰椎Modic改变的体积与终板缺损的体积、形态的相关性,探究相关终板病变与腰痛症状的联系。方法:回顾性分析2020年10月~2023年10月于苏州大学附属第二医院行腰椎MRI检查有终板缺损的401例患者的临床及影像资料,根据是否合并Modic改变分为两组:Modic改变组(204例)和无Modic改变组(197例),测量并计算两组患者终板缺损的体积分数并评估两组患者腰椎终板缺损的形态,分为典型形态组(凹陷形、三角形、圆形)和非典型形态组(矩形、不规则形)。测量Modic改变204例患者Modic改变的长、宽、高,并计算体积分数。分析Modic改变的体积分数与终板缺损的体积分数、形态的相关性。根据所有患者椎间盘退变等级分组,对每组患者分别进行Modic改变的体积分数与终板缺损的体积分数、形态分组的相关性分析。随访患者腰痛情况,对不同终板缺损形态与是否合并Modic改变患者腰痛患病率进行比较。结果:典型形态组共369个椎体,152个椎体合并Modic改变;非典型形态组共191个椎体,149个椎体合并Modic改变。Modic改变组的腰椎终板缺损体积分数为0.017±0.014,无Modic改变组的腰椎终板缺损体积分数为0.008±0.007。非典型形态组终板缺损患者的Modic改变体积分数0.20±0.13,典型形态组终板缺损患者Modic改变体积分数0.11±0.10,差异有统计学意义(P<0.001)。腰椎Modic改变的体积分数与终板缺损体积分数的变化呈线性正相关(P<0.001)。椎间盘轻度与中度退变的患者中,Modic改变的体积与终板缺损的体积与形态有着相关性(P<0.05);在椎间盘重度退变的患者中,Modic改变的体积与终板缺损的体积有着相关性(P<0.001),Modic改变的体积分数与终板缺损的形态之间未见相关性(P>0.05)。共随访65例患者腰痛情况,有30例患者出现腰痛症状(Modic改变组24例,无Modic改变组6例),终板缺损合并Modic改变的患者腰痛患病率高于单纯终板缺损患者(P<0.05),不同终板缺损形态患者腰痛患病率间无明显差异(P>0.05)。结论:腰椎Modic改变的体积分数与终板缺损的体积分数呈现显著的线性正相关性;椎间盘轻度与中度退变的患者中,非典型组形态的终板缺损患者的Modic改变体积分数普遍大于典型形态组;合并Modic改变患者中腰痛的比例更高。 展开更多
关键词 MODIC改变 终板缺损 MRI 腰痛 腰椎退行性变
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后路椎间盘镜下B-Twin椎间融合治疗退变性腰椎不稳 被引量:16
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作者 李春海 叶伟 +4 位作者 黄东生 苏培强 梁安靖 彭焰 刘尚礼 《中国骨与关节损伤杂志》 2008年第4期286-288,共3页
目的探讨椎间盘镜下B-Twin椎间融合治疗退变性腰椎不稳的手术疗效。方法收治退变性腰椎不稳16例16间隙,其中L1、21例,L4、510例,L5S15例。所有患者均辅以X线、CT或MRI检查,手术方式为后路椎间盘镜下B-Twin椎间融合术。结果术前Oswestry... 目的探讨椎间盘镜下B-Twin椎间融合治疗退变性腰椎不稳的手术疗效。方法收治退变性腰椎不稳16例16间隙,其中L1、21例,L4、510例,L5S15例。所有患者均辅以X线、CT或MRI检查,手术方式为后路椎间盘镜下B-Twin椎间融合术。结果术前Oswestry功能障碍指数ODI为(50.06±14.42)分,术后第3天(17.63±6.89)分(P<0.01),术后3个月(10.75±4.68)分(P<0.01),随访期末(9.06±3.38)分(P<0.01)。椎间隙高度保持良好,椎间融合器位置良好;1例融合器塌陷,15例植骨获融合,无感染、血肿、神经功能损伤及融合器脱落等其他并发症。结论后路椎间盘镜下B-Twin椎间融合治疗退变性腰椎不稳是一种创伤小、安全性高、效果好的手术方式,值得推广。 展开更多
关键词 退变性腰椎不稳 治疗 脊柱融合 椎间盘镜
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基于Cox健康行为互动模式的腰椎术后综合征预防管理方案的构建及应用
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作者 王婷婷 李呈慧 +2 位作者 吴春帅 顾海燕 高红 《护理学杂志》 CSCD 北大核心 2024年第18期11-15,23,共6页
目的改善腰椎退行性疾病患者术后腰椎功能,减轻疼痛,促进患者健康结局。方法按照入院时间将行腰椎后路手术的106例腰椎退行性疾病患者分为对照组及观察组各53例,对照组实施术后常规护理,观察组实施基于Cox健康行为互动模式的腰椎术后综... 目的改善腰椎退行性疾病患者术后腰椎功能,减轻疼痛,促进患者健康结局。方法按照入院时间将行腰椎后路手术的106例腰椎退行性疾病患者分为对照组及观察组各53例,对照组实施术后常规护理,观察组实施基于Cox健康行为互动模式的腰椎术后综合征预防管理方案。干预前后不同时间评价两组腰椎功能评分、疼痛评分及躯干偏移角度、骨盆扭转角度、椎体左右旋转最大角度之和。结果干预后1周、1个月、3个月观察组疼痛评分显著低于对照组,两组组间效应、时间效应差异有统计学意义(均P<0.05);干预后3个月、6个月观察组腰椎功能评分显著优于对照组(均P<0.05),两组组间效应、时间效应和交互效应差异有统计学意义(均P<0.05);干预后8周观察组躯干偏移角度、骨盆扭转角度及椎体左右旋转最大角度之和显著低于对照组(均P<0.05)。结论实施基于Cox健康行为互动模式的腰椎术后综合征预防管理方案,有利于缓解腰椎后路手术患者术后疼痛程度,提高腰椎稳定性及腰椎功能,促进患者康复。 展开更多
关键词 腰椎退行性疾病 腰椎后路手术 腰椎术后综合征 健康行为 疼痛 腰椎功能 康复训练
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单侧双通道脊柱内镜治疗退行性腰椎疾病疗效与影响因素的关系
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作者 方申雲 李海东 +4 位作者 张强华 闵继康 杨红航 李恒 张伟 《浙江创伤外科》 2024年第8期1419-1421,1425,共4页
目的探讨单侧双通道脊柱内镜(UBE)治疗退行性腰椎疾病(DLD)术后疗效与影响因素关系。方法对2021年2月至2023年3月收治本科室的61例DLD患者进行回顾性分析,评价其术后疗效。随访时间12~38个月。男35个,女26个,年龄19~81岁,平均年龄54.4... 目的探讨单侧双通道脊柱内镜(UBE)治疗退行性腰椎疾病(DLD)术后疗效与影响因素关系。方法对2021年2月至2023年3月收治本科室的61例DLD患者进行回顾性分析,评价其术后疗效。随访时间12~38个月。男35个,女26个,年龄19~81岁,平均年龄54.4岁。手术节段均为单节段,共61节段。记录患者围手术期及手术并发症情况;随访以末次随访为终止时间。采用疼痛视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)和改良MacNab标准评价临床疗效;手术前后行腰椎CT三维重建检查,观察并测量关节突关节切除内侧角(β角);椎间盘类型按照分类定位系统MSU(Michgan State University)基于MRI横断位分A、B、C区,依据区域定位法FSU(Functional Spine Unit)基于MRI或CT横断位、矢状位分级1~4级;统计采用配对t检验,及方差分析。结果61例患者均顺利完成手术。其中行腰椎间盘突出手术61例,其中合并中央管狭窄29例,合并侧隐窝狭窄54例。术中出现硬膜囊撕裂2例。术后出现短暂性下肢麻木3例,类脊髓综合征1例,感染1例。患者术后随访(12~38)个月。术后随访时,患者腿部VAS、ODI较术前明显下降(P值均<0.05)。术后末次随访时依据改良MacNab标准,优良率为65.6%(40/61)。腰椎三维CT影像学方面,测量β角均小于90°,平均值83.59°,范围(66.72°~89.32°)。基于MSU分区,A区37例,B区15例,C区9例;基于FSU位置分级,分别为1级1例,2级25例,3级2例,合并1和2级26例,2和3级4例,1和2、3级3例。方差分析显示术后满意度与椎间盘分区及分级、β角无关,与术后疼痛及功能障碍指数相关。结论单侧双通道脊柱内镜治疗退行性腰椎疾病术后疗效可能与术后β角及椎间盘分区、分级无关。分级、分区越复杂,手术难度越大,早期开展这项技术遇到的困难可能越多。 展开更多
关键词 单侧双通道脊柱内镜 退行性腰椎疾病 疗效 因素
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Topping-off技术治疗腰椎退变性疾病 被引量:3
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作者 赵成 徐建广 +2 位作者 连小峰 李浩 邱满乐 《国际骨科学杂志》 2013年第4期298-301,共4页
目的评价Toppingoff技术治疗连续双节段腰椎退变性疾病的中期临床疗效及相关影像学改变。方法2009年10月至2012年9月,采用Topping—off技术即后路腰椎椎间融合术(PLIF)联合Coflex棘突间动态固定装置置入术治疗18例连续双节段腰椎退... 目的评价Toppingoff技术治疗连续双节段腰椎退变性疾病的中期临床疗效及相关影像学改变。方法2009年10月至2012年9月,采用Topping—off技术即后路腰椎椎间融合术(PLIF)联合Coflex棘突间动态固定装置置入术治疗18例连续双节段腰椎退变性疾病患者。男6例,女12例;年龄40~63岁,平均5().3岁;L5~S1融合和L4~5Coflex装置置入16例,L4-5融合和L3-4。Coflex装置置入2例。按照Oswestry功能障碍指数(ODI)、疼痛视觉模拟评分(、vrAs)、日本骨科协会(JOA)腰椎功能评分评价术前及术后随访时的临床疗效,计算恢复率。经x线片检测腰椎整体活动度(L2~S1 ROM)、Coflex装置置入节段活动度(R()M)及椎间盘高度指数(DHI),经MRI图像计算Coflex装置置入节段椎间盘髓核相对信号强度(RSI)。结果术后随访6~30个月,平均13.6个月。ODI由术前52.60±5.80降至末次随访时16.90±5.70,VAS由术前8.30±0.85降至末次随访时1.60±0.87,JOA腰椎功能评分由术前11.5±3.70提高至23.80±2.30,差异均有统计学意义(P〈0.001)。18例患者术后恢复率评定均为显效,显效率为100%。L2~Sl ROM由术前20.10°±5.30。降至末次随访时16.30°±5.20°(P〈0.05),Coflex装置置入节段ROM由术前8.80°±1.90°降至末次随访时8.20°±1.80°(P=0.19),DHI由术前0.25±0.03增加至末次随访时0.34±0.03(P〈0.001),RSI由术前0.70l±0.058改善至末次随访时0.867±0.062(P%0.01)。结论Toppingoff技术治疗连续双节段腰椎退变性疾病可取得良好的中期疗效,Coflex装置对置人节段椎间盘修复及防止其退变的作用明显。 展开更多
关键词 腰椎 退行性疾病 腰椎椎间融合 非融合 动态固定
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单纯斜外侧腰椎间融合术后融合器下沉的危险因素及其对临床疗效的影响
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作者 马占兵 张树文 +1 位作者 沙西卡·那孜尔汗 王浩 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2024年第3期297-305,共9页
目的:探讨单纯斜外侧腰椎间融合术(stand-alone-oblique lateral interbody fusion,SA-OLIF)治疗退变性腰椎疾病术后融合器下沉的危险因素及其对临床疗效的影响。方法:回顾性分析2018年1月~2021年10月在我院行SA-OLIF手术治疗的89例腰... 目的:探讨单纯斜外侧腰椎间融合术(stand-alone-oblique lateral interbody fusion,SA-OLIF)治疗退变性腰椎疾病术后融合器下沉的危险因素及其对临床疗效的影响。方法:回顾性分析2018年1月~2021年10月在我院行SA-OLIF手术治疗的89例腰椎退变性疾病患者的临床资料。收集患者的一般资料[年龄、性别、体重指数(body mass index,BMI)、吸烟状况、激素使用情况、疾病类型以及是否合并骨质疏松]和手术相关资料[手术时间、术中出血量、手术节段、融合节段数、融合器高度],在腰椎正侧位及脊柱全长X线片上测量患者术前、术后1周手术融合节段椎间隙高度(disc height,DH)、腰椎前凸角(lumbar lordosis,LL),计算矫正值。术前和术后3个月、6个月、1年时进行Oswestry功能障碍指数(Oswestry disability index,ODI)评定及腰腿痛视觉模拟评分(visual analogue scale,VAS)。根据患者术后1年手术节段椎间隙高度丢失值将患者分为两组:DH丢失值≥2mm为下沉组(17例);DH丢失值<2mm为未下沉组(72例)。对可能影响融合器下沉的因素进行单因素统计分析及多因素logistic回归分析,确定SA-OLIF术后患者融合器下沉的危险因素及对临床疗效的影响。结果:两组患者的年龄、合并骨质疏松、融合器高度、术后1周DH、矫正DH等资料有统计学差异(P<0.05)。Logistic回归分析结果显示年龄(OR=2.889,95%CI:1.807,4.979)、合并骨质疏松(OR=3.753,95%CI:1.926,15.210)、术后1周DH(OR=2.777,95%CI:1.155,3.903)、矫正DH(OR=1.965,95%CI:1.523,4.334)为腰椎退行性变行SA-OLIF手术后融合器下沉的独立危险因素。两组间术前及术后3个月、6个月及1年时VAS评分及ODI的差异均无统计学意义(P>0.05)。结论:年龄大、骨质疏松严重、术中矫正DH大会增加融合器下沉风险;融合器下沉对SA-OLIF术后1年内的临床疗效无明显影响。 展开更多
关键词 退变性腰椎疾病 斜外侧腰椎间融合术 危险因素 融合器下沉
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单侧双通道内镜下腰椎融合术与微创经椎间孔入路椎间融合术治疗腰椎退行性疾病临床疗效比较的Meta分析
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作者 孙浩 李晨 +2 位作者 聂广龙 杨德顺 周建国 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2024年第4期389-401,共13页
目的:系统评价单侧双通道内镜下腰椎融合术(unilateral biportal endoscopic lumbar interbody fusion,ULIF)与微创经椎间孔入路腰椎融合术(minimally invasive transforaminal lumbar interbody fusion,MIS-TLIF)治疗腰椎退行性疾病(lu... 目的:系统评价单侧双通道内镜下腰椎融合术(unilateral biportal endoscopic lumbar interbody fusion,ULIF)与微创经椎间孔入路腰椎融合术(minimally invasive transforaminal lumbar interbody fusion,MIS-TLIF)治疗腰椎退行性疾病(lumbar degenerative disease,LDD)的临床疗效。方法:系统检索中国知网(CNKI)、维普(VIP)、万方数据(WanFang)、中国生物医学文献服务系统(SinoMed)、PubMed、Cochrane Library、Embase、Web of Science等8个中英文数据库中关于ULIF与MIS-TLIF治疗LDD的临床对照研究文献,检索时限为自数据库建库至2023年9月,采用纽卡斯尔-渥太华量表(Newcastle-Ottawa scale,NOS)对纳入的研究进行质量评价。提取手术时间、手术出血量、住院时间、疼痛视觉模拟(visual analog scale,VAS)评分、Oswestry功能障碍指数(Oswestry disability index,ODI)、并发症发生率、椎间盘高度、融合率等指标,应用RevMan 5.4.1软件进行Meta分析。结果:共纳入11篇文献,均为队列研究,NOS评价均为中高质量。共有800例患者,其中ULIF组380例,MIS-TLIF组420例。Meta分析结果显示,ULIF手术组腰部VAS(术后1~3个月)[MD=-0.43,95%CI(-0.70,-0.15)]、腰部VAS(末次随访>一年)[MD=-0.09,95%CI(-0.18,-0.00)]、ODI(术后1~3个月)[MD=-1.37,95%CI(-2.46,-0.28)]、住院时间[WMD=-0.75,95%CI(-1.33,-0.17)]、术中出血[MD=-78.72,95%CI(-113.20,-44.23)]等方面优于MIS-TILF手术组,MIS-TLIF手术组在手术时间[MD=30.28,95%CI(13.86,46.71)]上优于UILF手术组;二者在腿部VAS评分(术后1~3个月)[MD=-0.12,95%CI(-0.30,0.06)]、腿部VAS评分(末次随访>1年)[MD=-0.04,95%CI(-0.15,0.07)]、ODI(末次随访>1年)[MD=-0.46,95%CI(-1.02,0.11)]、腰椎前突角[MD=0.39,95%CI(-1.12,1.90)]、椎间盘高度[MD=0.03,95%CI(-0.24,0.30)]、融合率[MD=0.97,95%CI(0.92,1.03)]及并发症发生率[MD=0.82,95%CI(0.45,1.48)]等方面无明显差异。结论:相较于MIS-TLIF,ULIF在改善腰痛症状和早期恢复功能、减少术中出血、缩短住院时间等方面有优势,具有手术创伤小、恢复快的优势。二者在远期疗效、并发症以及融合率方面无明显差异。 展开更多
关键词 腰椎退行性疾病 单侧双通道内镜下腰椎融合术 微创经椎间孔入路腰椎融合术 META分析
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O型臂导航在微创经椎间孔腰椎椎间融合术治疗退行性腰椎滑脱症中的应用
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作者 陈胤 杨磊 徐峰 《联勤军事医学》 CAS 2024年第4期297-303,共7页
目的 比较O型臂导航辅助微创经椎间孔腰椎椎间融合术(minimally invasive transforaminal lumbar interbody fusion, MIS-TLIF)与C型臂辅助MIS-TLIF治疗退行性腰椎滑脱症的临床疗效。方法 对2022-06/2023-06月42例在作者医院行O型臂辅助... 目的 比较O型臂导航辅助微创经椎间孔腰椎椎间融合术(minimally invasive transforaminal lumbar interbody fusion, MIS-TLIF)与C型臂辅助MIS-TLIF治疗退行性腰椎滑脱症的临床疗效。方法 对2022-06/2023-06月42例在作者医院行O型臂辅助或C型臂辅助MIS-TLIF治疗单节段退行性腰椎滑脱症患者的资料进行分析。依据手术类型将患者分为O型臂辅助MIS-TLIF组(n=20)和C型臂辅助MIS-TLIF组(n=22),O型臂辅助MIS-TLIF组患者接受O型臂辅助MIS-TLIF治疗,C型臂辅助MIS-TLIF组患者接受C型臂辅助MIS-TLIF治疗。比较两组退行性腰椎滑脱症患者人口统计学变量、围手术期指标、背部与腿部疼痛视觉模拟量表(visual analogu scale, VAS)评分、Oswestry残疾指数(Oswestry disability index, ODI)及临床结局。结果 O型臂辅助MIS-TLIF组患者术中出血量、术后引流量显著低于C型臂辅助MIS-TLIF组,差异有统计学意义(P均<0.05)。O型臂辅助MIS-TLIF组退行性腰椎滑脱症患者的置钉准确率明显高于C型臂辅助MIS-TLIF组,差异有统计学意义(P<0.05)。两组退行性腰椎滑脱症患者背痛VAS评分、ODI评分随时间不断降低(P均<0.05)。同一时间点比较,术前两组退行性腰椎滑脱症患者背痛VAS评分、ODI评分比较差异无统计学意义(P>0.05),术后1周与术后3个月,O型臂辅助MIS-TLIF组退行性腰椎滑脱症患者背痛VAS评分、ODI评分低于C型臂辅助MIS-TLIF组(P均<0.05),其余时间点两组退行性腰椎滑脱症患者背痛VAS评分、ODI评分差异无统计学意义(P>0.05)。两组退行性腰椎滑脱症患者腿痛VAS评分随时间不断降低(P均<0.05)。两组退行性腰椎滑脱症患者各时间点腿痛VAS评分比较差异无统计学意义(P>0.05)。O型臂辅助MIS-TLIF组、C型臂辅助MIS-TLIF组退行性腰椎滑脱症Odom标准总体优良率分别为85.00%、 90.91%,二者比较差异无统计学意义(P>0.05)。两组退行性腰椎滑脱症患者在术后12个月复查时均无融合失败病例,均无相关并发症发生。结论 O型臂导航辅助MIS-TLIF治疗单节段Ⅰ~Ⅱ级退行性腰椎滑脱症安全有效,相较于C型臂辅助MIS-TLIF具有置钉的精确度高、手术创伤小、术后疼痛较轻等优势。 展开更多
关键词 O型臂导航 微创经椎间孔腰椎椎间融合术 退行性腰椎滑脱症 脊柱退行性疾病
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基于虚拟现实技术的退行性腰椎疾病患者预康复促进和障碍因素的质性研究
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作者 王小影 高娜娜 +2 位作者 郭敬然 孟小娜 胡惠菊 《中西医结合护理》 2024年第6期62-68,共7页
目的探讨虚拟现实技术在退行性腰椎疾病预康复中应用的促进和障碍因素。方法以实施性研究综合框架(CFIR)为理论基础,采用质性研究方法,通过目的抽样,对唐山市第二医院脊柱科10名应用虚拟现实设备的患者和5名护士进行半结构式访谈,并对... 目的探讨虚拟现实技术在退行性腰椎疾病预康复中应用的促进和障碍因素。方法以实施性研究综合框架(CFIR)为理论基础,采用质性研究方法,通过目的抽样,对唐山市第二医院脊柱科10名应用虚拟现实设备的患者和5名护士进行半结构式访谈,并对访谈内容进行分析。结果基于虚拟现实技术预康复项目在退行性腰椎疾病患者中实施的促进因素包括创新领域中的创新相对优势及内部特征领域中的沟通、变革的迫切性和与现有工作流程相符的兼容性;障碍因素包括创新领域中的创新成本及设计质量和包装,外部特征因素领域的协作关系,内部特征领域中的激励制度及知识和信息的可及性;中性因素包括内部特征领域中的场所,个体特征领域中的实施促进者,实施过程领域中的反馈与评价。结论虚拟现实技术可以促进退性腰椎疾病预康复更好的实施,从而降低患者围手术期恐动程度,减轻疼痛,促进快速康复;但要选择合适舒适的设备提供个性化、多元化、游戏化的康复项目以克服其障碍因素。 展开更多
关键词 实施性研究综合框架 预康复 虚拟现实技术 退行性腰椎疾病
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TLIF与OLIF联合后路内固定治疗腰椎退行性疾病的疗效比较 被引量:1
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作者 罗金伟 徐国康 +5 位作者 屠玉兰 苏棋 沈童 张弘 陈飞 陈子航 《浙江临床医学》 2024年第1期93-95,共3页
目的比较斜外侧腰椎椎间融合术(OLIF)联合后路椎弓根钉棒内固定术与经椎间孔入路腰椎间融合术(TLIF)治疗退行性腰椎疾病的疗效。方法回顾性分析2018年3月至2022年11月65例行手术治疗的退行性腰椎疾病患者的临床资料,其中35例行OLIF联合... 目的比较斜外侧腰椎椎间融合术(OLIF)联合后路椎弓根钉棒内固定术与经椎间孔入路腰椎间融合术(TLIF)治疗退行性腰椎疾病的疗效。方法回顾性分析2018年3月至2022年11月65例行手术治疗的退行性腰椎疾病患者的临床资料,其中35例行OLIF联合后路椎弓根钉棒内固定术治疗(OLIF组),30例行经椎间孔入路腰椎间融合术治疗(TLIF组)。记录两组围术期相关指标、术后并发症发生情况,比较两组术前、术后1个月、术后3个月疼痛视觉模拟评分(VAS)和Oswestry功能障碍指数(ODI),以及术前、术后椎间隙及椎间孔高度。结果与TLIF组比较,OLIF组术中出血量、术后下地行走时间、术后住院时间、术后椎间隙高度、椎间孔高度、术后椎间隙及椎间孔高度、VAS评分、ODI指数及并发症发生率均有优势(P<0.05)。结论两种手术方式均能有效治疗退行性腰椎疾病,OLIF联合后路椎弓根钉棒内固定术对椎间隙及椎间孔恢复更具有优势,术中出血少,术后恢复更快,在单节段退行性腰椎疾病的治疗效果更优。 展开更多
关键词 腰椎退行性疾病 斜外侧腰椎椎间融合术 经椎间孔入路腰椎间融合术 围术期相关指标
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改良经皮经椎间孔腰椎椎体间融合术治疗腰椎退行性疾病的疗效分析
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作者 龚俊峰 汤宇 +4 位作者 常献 张超 郑文杰 周跃 李长青 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2024年第4期348-354,共7页
目的:分析改良经皮经椎间孔腰椎椎体间融合术(modified percutaneous transforaminal lumbar interbody fusion,MPTLIF)治疗腰椎退行性疾病的早期临床疗效。方法:回顾性分析2020年1月~2021年10月在陆军军医大学附属第二医院接受MPTLIF... 目的:分析改良经皮经椎间孔腰椎椎体间融合术(modified percutaneous transforaminal lumbar interbody fusion,MPTLIF)治疗腰椎退行性疾病的早期临床疗效。方法:回顾性分析2020年1月~2021年10月在陆军军医大学附属第二医院接受MPTLIF治疗的26例腰椎退行性疾病患者的临床资料,其中男性12例,女性14例;年龄44~77岁(58.3±8.4岁);腰椎滑脱症16例,腰椎不稳伴神经根管狭窄症10例;L3/43例,L4/523例。统计患者手术时间、术中出血量、术后住院时间和术后引流量,术前、术后3d、术后3个月和末次随访时进行疼痛视觉模拟评分(visual analogue scale,VAS),术前、术后3个月和末次随访时行Oswestry功能障碍指数(Oswestry disability index,ODI)评定,末次随访时采用改良MacNab疗效评定标准评价临床疗效。在术前和末次随访时的X线片和CT片上测量椎间隙前后缘高度、腰椎前凸角和手术节段前凸角。结果:所有患者均顺利完成手术,手术时间98.9±6.6min,术中出血量41.0±12.6mL,术后引流量38.1±9.5mL,术后平均住院时间3.8±0.9d,无硬膜外血肿、感染或肌肉麻痹瘫痪等并发症。随访17.7±4.2个月,术前和术后3d、术后3个月和末次随访时的VAS评分分别为5.85±0.67分、2.15±0.54分、1.12±0.33分、0.54±0.51分,术前、术后3个月和末次随访时的ODI分别为(47.38±6.66)%、(11.73±6.73)%、(6.58±6.51)%,术后各时间点的VAS评分和ODI与术前比较均显著性改善(P<0.05),且随着术后时间推移有进一步改善(P<0.05);末次随访时改良MacNab疗效评定标准评定优24例,良2例。末次随访时椎间隙前后缘高度(前缘10.95±1.24mm、后缘9.45±1.13mm)、腰椎前凸角(47.38°±4.56°)和手术节段前凸角(8.62°±1.92°)均较术前(前缘8.85±1.00mm、后缘6.78±1.07mm、43.81°±4.85°、6.62°±2.02°)有显著性改善(P<0.05)。结论:对严格适应证选择的病例,MPTLIF是一种安全、有效的微创治疗术式,治疗腰椎退行性疾病能够获得良好的早期临床疗效。 展开更多
关键词 腰椎退行性疾病 改良经皮经椎间孔腰椎椎体间融合术 微创脊柱外科
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V形双通道脊柱内镜技术治疗老年退行性腰椎滑脱症疗效观察
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作者 李雷 庞超见 赵新亮 《新乡医学院学报》 CAS 2024年第7期674-679,共6页
目的探讨V形双通道脊柱内镜技术(VBE)治疗老年退行性腰椎滑脱症(DLS)的临床效果。方法选择2017年6月至2023年4月武安市第一人民医院收治的110例DLS患者为研究对象。根据手术方案将患者分为微创经椎间孔椎体间融合术(MIS-TLIF)组和VBE组... 目的探讨V形双通道脊柱内镜技术(VBE)治疗老年退行性腰椎滑脱症(DLS)的临床效果。方法选择2017年6月至2023年4月武安市第一人民医院收治的110例DLS患者为研究对象。根据手术方案将患者分为微创经椎间孔椎体间融合术(MIS-TLIF)组和VBE组,每组55例。记录2组患者手术切口长度、手术时间、X线透视次数、术中出血量、住院时间、卧床时间等术中及术后一般指标;分别于术前及术后3、6个月采用视觉模拟评分法(VAS)评估腰背、腿疼痛程度,采用Oswestry功能障碍指数(ODI)评估患者的腰椎功能;术后3个月采用Brantigan评分评估患者骨粒融合情况;术前及术后3、6个月拍摄X线片,测量患者的手术节段椎体滑移度、椎间隙高度、滑脱角、矢状面Cobb角;术后6个月采用日本整形外科学会(JOA)评分评估患者腰椎功能优良率;记录2组患者术后并发症发生情况。结果VBE组患者的手术切口长度、手术时间、卧床时间、住院时间显著短于MIS-TLIF组,术中出血量、X线透视次数显著少于MIS-TLIF组(P<0.05)。术前,2组患者腰背痛VAS评分、腿痛VAS评分、ODI指数比较差异无统计学意义(P>0.05);2组患者术后3、6个月腰背痛VAS评分、腿痛VAS评分、ODI指数均显著低于术前(P<0.05);术后3、6个月,VBE组与MIS-TLIF组患者腰背痛VAS评分、腿痛VAS评分、ODI指数比较差异无统计学意义(P>0.05)。VBE组与MIS-TLIF组患者Brantigan评分分布比较差异无统计学意义(P>0.05)。术前,2组患者手术节段矢状面Cobb角、椎间隙高度、滑脱角、椎体滑移度比较差异无统计学意义(P>0.05)。2组患者术后3、6个月手术节段矢状面Cobb角、椎间隙高度显著高于术前(P<0.05),滑脱角、椎体滑移度显著低于术前(P<0.05);术后3、6个月,2组患者手术节段矢状面Cobb角、椎间隙高度、滑脱角、椎体滑移度比较差异无统计学意义(P>0.05)。术后6个月,VBE组与MIS-TLIF组患者腰椎功能优良率分别为100.00%(55/55)、98.18%(54/55),2组患者腰椎功能优良率比较差异无统计学意义(P>0.05)。术后,VBE组患者未出现并发症,MIS-TLIF组1例患者出现切口渗出和延迟愈合。结论VBE治疗老年DLS在腰椎形态、功能恢复及安全性方面效果与MIS-TLIF相当,但VBE能减轻组织损伤,使患者及早下床活动,缩短患者术后早期恢复进程。 展开更多
关键词 退行性腰椎滑脱症 微创经椎间孔椎体间融合术 V形双通道脊柱内镜技术 疼痛程度 融合情况 腰椎解剖参数 腰椎功能 并发症
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