AIM:To compare success rates and complications of Densiron 68 and 1000cSt silicone oil (SO) in the management of rhegmatogenous retinal detachment (RRD) with inferior breaks (IBs). METHODS:Totally 61 eyes of 61 consec...AIM:To compare success rates and complications of Densiron 68 and 1000cSt silicone oil (SO) in the management of rhegmatogenous retinal detachment (RRD) with inferior breaks (IBs). METHODS:Totally 61 eyes of 61 consecutive patients with RRD with IBs were assigned to pars plana vitrectomy (PPV) with Densiron (n =31) or PPV with SO (n=30) in order of presentation. SO and Densiron removal was performed 3 months after initial surgery. Follow up visits were terminated 6 months after SO removal. ·RESULTS:With a single operation, the Densiron group showed 84% and SO 74% reattachment. With further surgery, both groups showed 90% reattachment. Complications such as cataract, raised intraocular pressure (IOP), inflammatory reaction, macular epiretinal membranes, and emulsification of SO were seen in both groups. CONCLUSION:Densiron and SO are found to have similar success rates and complications.展开更多
AIM: To assess the efficacy and safety of a heavy silicone oil(Densiron 68) in the management of inferior retinal detachment recurrence.METHODS: A retrospective non-comparative consecutive case series study. Forty-nin...AIM: To assess the efficacy and safety of a heavy silicone oil(Densiron 68) in the management of inferior retinal detachment recurrence.METHODS: A retrospective non-comparative consecutive case series study. Forty-nine cases of complex inferior retinal detachment were treated using Densiron 68 heavy silicone oil(HSO) as the endotamponade. Our main purpose was anatomic reattachment following Densiron 68 removal. Functional outcomes, rate of recurrences, the presence of inflammatory complications and intraocular pressure alterations were evaluated. RESULTS: Forty-nine patients affected by complex retinal re-detachment were recruited. The mean follow-up was 7.6(±1.5) mo. The mean best corrected visual acuity after Densiron 68 removal was 0.95 log MAR, standard error(SE: 0.068). Retinal reattachment was 61.2% after first surgery and 81.6% after second surgery. Nineteen cases(38.8%) had recurrences when intraocular heavy silicon oil was in situ, 26.3%(5 cases) of which involved the inferior retina. CONCLUSION: Densiron 68 efficiently fills the inferior retinal periphery and might lower the risk of inferior proliferative vitreoretinopathy development, in particular after a standard silicon oil tamponade that reduces the proliferative process in the upper quadrants of the retina.展开更多
Background:In this study,we evaluated the anatomic and functional outcome and intraocular adverse effects after a 3-month endotamponade with Densiron 68,a mixture of F6H8 with silicone oil,in complex inferior redetach...Background:In this study,we evaluated the anatomic and functional outcome and intraocular adverse effects after a 3-month endotamponade with Densiron 68,a mixture of F6H8 with silicone oil,in complex inferior redetachments.Methods:Forty-eight eyes of 48 patients aged 27-82 years with retinal redetachment due to proliferative vitreoretinopathy(PVR)grades CP1 to CA7 were included.Mean duration of the Densiron endotamponade was 108.7± 66.9 days,with a mean followup after removal of 102.8± 31.9 days.Results:Twenty-two patients(45.8%)showed stable retinal reattachment after Densiron removal.Fourteen patients(29.2%)developed retinal re-detachment after removal,generally within 1 month and in the upper circumference(n=8).In 11 patients(22.9%)recurrent re-detachment(inferior n=8)appeared during Densiron endotamponade.In one eye(2.1%)treatment was primarily unsuccessful.Visual acuity improved from mean logMAR 1.66± 1.03 to 1.47± 0.97(not statistically significant,P=0.257).Side effects included temporary inflammatory reaction(n=10),fibrin accumulation(n=6),sterile hypopyon(n=2),vitreous hemorrhage(n=6),elevated IOP(n=5),emulsification(n=4)and chronic hypotony(n=4).Conclusion:The anatomical success rate without further interventions of 45.8%(22 of 48 patients)seems unsatisfactory.However,in evaluating the potential of Densiron,it should be considered that all patients in this study had previous surgery with standard procedures,including silicone oil,which had already failed.Intraoperative laser photocoagulation of the periphery of the upper quadrants might reduce the risk of retinal re-detachments.展开更多
文摘AIM:To compare success rates and complications of Densiron 68 and 1000cSt silicone oil (SO) in the management of rhegmatogenous retinal detachment (RRD) with inferior breaks (IBs). METHODS:Totally 61 eyes of 61 consecutive patients with RRD with IBs were assigned to pars plana vitrectomy (PPV) with Densiron (n =31) or PPV with SO (n=30) in order of presentation. SO and Densiron removal was performed 3 months after initial surgery. Follow up visits were terminated 6 months after SO removal. ·RESULTS:With a single operation, the Densiron group showed 84% and SO 74% reattachment. With further surgery, both groups showed 90% reattachment. Complications such as cataract, raised intraocular pressure (IOP), inflammatory reaction, macular epiretinal membranes, and emulsification of SO were seen in both groups. CONCLUSION:Densiron and SO are found to have similar success rates and complications.
文摘AIM: To assess the efficacy and safety of a heavy silicone oil(Densiron 68) in the management of inferior retinal detachment recurrence.METHODS: A retrospective non-comparative consecutive case series study. Forty-nine cases of complex inferior retinal detachment were treated using Densiron 68 heavy silicone oil(HSO) as the endotamponade. Our main purpose was anatomic reattachment following Densiron 68 removal. Functional outcomes, rate of recurrences, the presence of inflammatory complications and intraocular pressure alterations were evaluated. RESULTS: Forty-nine patients affected by complex retinal re-detachment were recruited. The mean follow-up was 7.6(±1.5) mo. The mean best corrected visual acuity after Densiron 68 removal was 0.95 log MAR, standard error(SE: 0.068). Retinal reattachment was 61.2% after first surgery and 81.6% after second surgery. Nineteen cases(38.8%) had recurrences when intraocular heavy silicon oil was in situ, 26.3%(5 cases) of which involved the inferior retina. CONCLUSION: Densiron 68 efficiently fills the inferior retinal periphery and might lower the risk of inferior proliferative vitreoretinopathy development, in particular after a standard silicon oil tamponade that reduces the proliferative process in the upper quadrants of the retina.
文摘Background:In this study,we evaluated the anatomic and functional outcome and intraocular adverse effects after a 3-month endotamponade with Densiron 68,a mixture of F6H8 with silicone oil,in complex inferior redetachments.Methods:Forty-eight eyes of 48 patients aged 27-82 years with retinal redetachment due to proliferative vitreoretinopathy(PVR)grades CP1 to CA7 were included.Mean duration of the Densiron endotamponade was 108.7± 66.9 days,with a mean followup after removal of 102.8± 31.9 days.Results:Twenty-two patients(45.8%)showed stable retinal reattachment after Densiron removal.Fourteen patients(29.2%)developed retinal re-detachment after removal,generally within 1 month and in the upper circumference(n=8).In 11 patients(22.9%)recurrent re-detachment(inferior n=8)appeared during Densiron endotamponade.In one eye(2.1%)treatment was primarily unsuccessful.Visual acuity improved from mean logMAR 1.66± 1.03 to 1.47± 0.97(not statistically significant,P=0.257).Side effects included temporary inflammatory reaction(n=10),fibrin accumulation(n=6),sterile hypopyon(n=2),vitreous hemorrhage(n=6),elevated IOP(n=5),emulsification(n=4)and chronic hypotony(n=4).Conclusion:The anatomical success rate without further interventions of 45.8%(22 of 48 patients)seems unsatisfactory.However,in evaluating the potential of Densiron,it should be considered that all patients in this study had previous surgery with standard procedures,including silicone oil,which had already failed.Intraoperative laser photocoagulation of the periphery of the upper quadrants might reduce the risk of retinal re-detachments.
