Seismic data with high signal-to-noise ratios(SNRs) are useful in reservoir exploration. To obtain high SNR seismic data, significant effort is required to achieve noise attenuation in seismic data processing, which i...Seismic data with high signal-to-noise ratios(SNRs) are useful in reservoir exploration. To obtain high SNR seismic data, significant effort is required to achieve noise attenuation in seismic data processing, which is costly in materials, and human and financial resources. We introduce a method for improving the SNR of seismic data. The SNR is calculated by using the frequency domain method. Furthermore, we optimize and discuss the critical parameters and calculation procedure. We applied the proposed method on real data and found that the SNR is high in the seismic marker and low in the fracture zone. Consequently, this can be used to extract detailed information about fracture zones that are inferred by structural analysis but not observed in conventional seismic data.展开更多
Based on chaotic oscillator system, this paper proposes a novel method on high frequency low signal- to-noise ratio BPSK( Binary Phase Shift Keying) signal detection. Chaotic oscillator system is a typical non-lin- ...Based on chaotic oscillator system, this paper proposes a novel method on high frequency low signal- to-noise ratio BPSK( Binary Phase Shift Keying) signal detection. Chaotic oscillator system is a typical non-lin- ear system which is sensitive to periodic signals and immune to noise at the same time. Those properties make it possible to detect low signal-to-noise ratio signals. The BPSK signal is a common signal type which is widely used in modern communication. Starting from the analysis of advantages of chaotic, os~.illator system and signal features of the BPSK signal, we put forward a unique method that can detect low signar-to-noise ratio BPSK sig- nals with high frequency. The simulation results show that the novel method can dclct.t low signal-to-noise ratio BPSK signals with frequency in an order of magnitude of l0s Hz, and the input Signal-to-Noise Ratio threshold can be -20 dB.展开更多
Template matching is a useful method to detect seismic events through waveform similarity between two signals.The traditional template matching method works well in detecting small tectonic earthquakes.However,the met...Template matching is a useful method to detect seismic events through waveform similarity between two signals.The traditional template matching method works well in detecting small tectonic earthquakes.However,the method has some difficulty when the signals have relatively low signal-to-noise ratios(SNRs)and simple shapes,e.g.a sinusoidal function.In this study,we modify the traditional template matching approach for this situation.We first construct a virtual three-component seismic station using vertical-component waveforms recorded by three stations.Next,we select a template event from the virtual station,and apply the traditional template matching.We then verify this method by detecting icequakes with simple waveforms on the Urumqi Glacier No.1 and compare the results with those from the short-term-averages over long-term-average(STA/LTA),the REST method,and traditional template matching method.It can be concluded that the modified template matching method using virtual stations has some advantages for seismic data with low SNRs.展开更多
Background: The signal-to-noise ratio (SNR) is recognized as an index of measurements reproducibility. We derive the maximum likelihood estimators of SNR and discuss confidence interval construction on the difference ...Background: The signal-to-noise ratio (SNR) is recognized as an index of measurements reproducibility. We derive the maximum likelihood estimators of SNR and discuss confidence interval construction on the difference between two correlated SNRs when the readings are from bivariate normal and bivariate lognormal distribution. We use the Pearsons system of curves to approximate the difference between the two estimates and use the bootstrap methods to validate the approximate distributions of the statistic of interest. Methods: The paper uses the delta method to find the first four central moments, and hence the skewness and kurtosis which are important in the determination of the parameters of the Pearsons distribution. Results: The approach is illustrated in two examples;one from veterinary microbiology and food safety data and the other on data from clinical medicine. We derived the four central moments of the target statistics, together with the bootstrap method to evaluate the parameters of Pearsons distribution. The fitted Pearsons curves of Types I and II were recommended based on the available data. The R-codes are also provided to be readily used by the readers.展开更多
Food safety problems caused by excessive nitrite addition have been frequently reported and the detection of nitrite in food is particularly important. The standing time during the pretreatment of primary sample has a...Food safety problems caused by excessive nitrite addition have been frequently reported and the detection of nitrite in food is particularly important. The standing time during the pretreatment of primary sample has a great influence on the concentration of nitrite tested by spectrophotometric method. In this context, three kinds of food samples are prepared, including canned mustard, canned fish and home-made pickled water. A series of standing times are placed during the sample pretreatments and the corresponding nitrite contents in these samples are detected by spectrophotometric method based on N-ethylenediamine dihydrochloride. This study aims to find out a reasonable standing time during the pretreatment of food sample, providing influence factor for precise detection of nitrite.展开更多
We report a method of high-sensitively detecting the weak signal in photoassociation (PA) spectra of ultracold NaCs molecules by phase sensitive-demodulated trap-loss spectra of Na atoms from a photomultiplier tube....We report a method of high-sensitively detecting the weak signal in photoassociation (PA) spectra of ultracold NaCs molecules by phase sensitive-demodulated trap-loss spectra of Na atoms from a photomultiplier tube. We find that the signal-to-noise ratio (SNR) of the PA spectra is strongly dependent on the integration time and the sensitivity of the lock-in amplifier, and our results show reasonable agreement with the theoretical analyses of the SNR with the demodulation parameters. Meanwhile, we investigate the effect of the interaction time of the PA laser with the colliding Na-Cs atom pairs on the SNR of the PA spectra. The atom loss rate is dependent on both the PA-induced atom loss and the loading of the MOT. The high-sensitive detection of the excited ultracold NaCs molecules lays a solid foundation for further study of the formation and application of ultracold NaCs molecules.展开更多
Raman spectroscopy has been widely used to characterize the physical properties of two-dimensional materials(2DMs).The signal-to-noise ratio(SNR or S/N ratio)of Raman signal usually serves as an important indicator to...Raman spectroscopy has been widely used to characterize the physical properties of two-dimensional materials(2DMs).The signal-to-noise ratio(SNR or S/N ratio)of Raman signal usually serves as an important indicator to evaluate the instrumental performance rather than Raman intensity itself.Multichannel detectors with outstanding sensitivity,rapid acquisition speed and low noise level have been widely equipped in Raman instruments for the measurement of Raman signal.In this mini-review,we first introduce the recent advances of Raman spectroscopy of 2DMs.Then we take the most commonly used CCD detector and IGA array detector as examples to overview the various noise sources in Raman measurements and analyze their potential influences on SNR of Raman signal in experiments.This overview can contribute to a better understanding on the SNR of Raman signal and the performance of multichannel detector for numerous researchers and instrumental design for industry,as well as offer practical strategies for improving spectral quality in routine measurement.展开更多
Lung cancer continues to be a leading cause of cancer-related deaths worldwide,emphasizing the critical need for improved diagnostic techniques.Early detection of lung tumors significantly increases the chances of suc...Lung cancer continues to be a leading cause of cancer-related deaths worldwide,emphasizing the critical need for improved diagnostic techniques.Early detection of lung tumors significantly increases the chances of successful treatment and survival.However,current diagnostic methods often fail to detect tumors at an early stage or to accurately pinpoint their location within the lung tissue.Single-model deep learning technologies for lung cancer detection,while beneficial,cannot capture the full range of features present in medical imaging data,leading to incomplete or inaccurate detection.Furthermore,it may not be robust enough to handle the wide variability in medical images due to different imaging conditions,patient anatomy,and tumor characteristics.To overcome these disadvantages,dual-model or multi-model approaches can be employed.This research focuses on enhancing the detection of lung cancer by utilizing a combination of two learning models:a Convolutional Neural Network(CNN)for categorization and the You Only Look Once(YOLOv8)architecture for real-time identification and pinpointing of tumors.CNNs automatically learn to extract hierarchical features from raw image data,capturing patterns such as edges,textures,and complex structures that are crucial for identifying lung cancer.YOLOv8 incorporates multiscale feature extraction,enabling the detection of tumors of varying sizes and scales within a single image.This is particularly beneficial for identifying small or irregularly shaped tumors that may be challenging to detect.Furthermore,through the utilization of cutting-edge data augmentation methods,such as Deep Convolutional Generative Adversarial Networks(DCGAN),the suggested approach can handle the issue of limited data and boost the models’ability to learn from diverse and comprehensive datasets.The combined method not only improved accuracy and localization but also ensured efficient real-time processing,which is crucial for practical clinical applications.The CNN achieved an accuracy of 97.67%in classifying lung tissues into healthy and cancerous categories.The YOLOv8 model achieved an Intersection over Union(IoU)score of 0.85 for tumor localization,reflecting high precision in detecting and marking tumor boundaries within the images.Finally,the incorporation of synthetic images generated by DCGAN led to a 10%improvement in both the CNN classification accuracy and YOLOv8 detection performance.展开更多
Security and safety remain paramount concerns for both governments and individuals worldwide.In today’s context,the frequency of crimes and terrorist attacks is alarmingly increasing,becoming increasingly intolerable...Security and safety remain paramount concerns for both governments and individuals worldwide.In today’s context,the frequency of crimes and terrorist attacks is alarmingly increasing,becoming increasingly intolerable to society.Consequently,there is a pressing need for swift identification of potential threats to preemptively alert law enforcement and security forces,thereby preventing potential attacks or violent incidents.Recent advancements in big data analytics and deep learning have significantly enhanced the capabilities of computer vision in object detection,particularly in identifying firearms.This paper introduces a novel automatic firearm detection surveillance system,utilizing a one-stage detection approach named MARIE(Mechanism for Realtime Identification of Firearms).MARIE incorporates the Single Shot Multibox Detector(SSD)model,which has been specifically optimized to balance the speed-accuracy trade-off critical in firearm detection applications.The SSD model was further refined by integrating MobileNetV2 and InceptionV2 architectures for superior feature extraction capabilities.The experimental results demonstrate that this modified SSD configuration provides highly satisfactory performance,surpassing existing methods trained on the same dataset in terms of the critical speedaccuracy trade-off.Through these innovations,MARIE sets a new standard in surveillance technology,offering a robust solution to enhance public safety effectively.展开更多
Liver cancer remains a leading cause of mortality worldwide,and precise diagnostic tools are essential for effective treatment planning.Liver Tumors(LTs)vary significantly in size,shape,and location,and can present wi...Liver cancer remains a leading cause of mortality worldwide,and precise diagnostic tools are essential for effective treatment planning.Liver Tumors(LTs)vary significantly in size,shape,and location,and can present with tissues of similar intensities,making automatically segmenting and classifying LTs from abdominal tomography images crucial and challenging.This review examines recent advancements in Liver Segmentation(LS)and Tumor Segmentation(TS)algorithms,highlighting their strengths and limitations regarding precision,automation,and resilience.Performance metrics are utilized to assess key detection algorithms and analytical methods,emphasizing their effectiveness and relevance in clinical contexts.The review also addresses ongoing challenges in liver tumor segmentation and identification,such as managing high variability in patient data and ensuring robustness across different imaging conditions.It suggests directions for future research,with insights into technological advancements that can enhance surgical planning and diagnostic accuracy by comparing popular methods.This paper contributes to a comprehensive understanding of current liver tumor detection techniques,provides a roadmap for future innovations,and improves diagnostic and therapeutic outcomes for liver cancer by integrating recent progress with remaining challenges.展开更多
A measurement system for the scattering characteristics of warhead fragments based on high-speed imaging systems offers advantages such as simple deployment,flexible maneuverability,and high spatiotemporal resolution,...A measurement system for the scattering characteristics of warhead fragments based on high-speed imaging systems offers advantages such as simple deployment,flexible maneuverability,and high spatiotemporal resolution,enabling the acquisition of full-process data of the fragment scattering process.However,mismatches between camera frame rates and target velocities can lead to long motion blur tails of high-speed fragment targets,resulting in low signal-to-noise ratios and rendering conventional detection algorithms ineffective in dynamic strong interference testing environments.In this study,we propose a detection framework centered on dynamic strong interference disturbance signal separation and suppression.We introduce a mixture Gaussian model constrained under a joint spatialtemporal-transform domain Dirichlet process,combined with total variation regularization to achieve disturbance signal suppression.Experimental results demonstrate that the proposed disturbance suppression method can be integrated with certain conventional motion target detection tasks,enabling adaptation to real-world data to a certain extent.Moreover,we provide a specific implementation of this process,which achieves a detection rate close to 100%with an approximate 0%false alarm rate in multiple sets of real target field test data.This research effectively advances the development of the field of damage parameter testing.展开更多
BACKGROUND Diagnosing bacterial infections(BI)in patients with cirrhosis can be challenging because of unclear symptoms,low diagnostic accuracy,and lengthy culture testing times.Various biomarkers have been studied,in...BACKGROUND Diagnosing bacterial infections(BI)in patients with cirrhosis can be challenging because of unclear symptoms,low diagnostic accuracy,and lengthy culture testing times.Various biomarkers have been studied,including serum procal-citonin(PCT)and presepsin.However,the diagnostic performance of these markers remains unclear,requiring further informative studies to ascertain their diagnostic value.AIM To evaluate the pooled diagnostic performance of PCT and presepsin in detecting BI among patients with cirrhosis.INTRODUCTION Bacterial infections(BI)commonly occur in patients with cirrhosis,resulting in poor outcomes,including the development of cirrhotic complications,septic shock,acute-on-chronic liver failure(ACLF),multiple organ failures,and mortality[1,2].BI is observed in 20%-30%of hospitalized patients,with and without ACLF[3].Patients with cirrhosis are susceptible to BI because of internal and external factors.The major internal factors are changes in gut microbial composition and function,bacterial translocation,and cirrhosis-associated immune dysfunction syndrome[4,5].External factors include alcohol use,proton-pump inhibitor use,frailty,readmission,and invasive procedures.Spontaneous bacterial peritonitis(SBP),urinary tract infection,pneumonia,and primary bacteremia are the common BIs in hospit-alized patients with cirrhosis[6].Early diagnosis and adequate empirical antibiotic therapy are two critical factors that improve the prognosis of BI in patients with cirrhosis.However,early detection of BI in cirrhosis is challenging due to subtle clinical signs and symptoms,low sensitivity and specificity of systemic inflammatory response syndrome criteria,and low sensitivity of bacterial cultures.Thus,effective biomarkers need to be identified for the early detection of BI.Several biomarkers have been evaluated,but their efficacy in detecting BI is unclear.Procalcitonin(PCT)is a precursor of the hormone calcitonin,which is secreted by parafollicular cells of the thyroid gland[7].In the presence of BI,PCT gene expression increases in extrathyroidal tissues,causing a subsequent increase in serum PCT level[8].Changes in serum PCT are detectable as early as 4 hours after infection onset and peaks between 8 and 24 hours,making it a valuable diagnostic biomarker for BI.Several studies have demonstrated the favorable diagnostic accuracy of PCT in the diagnosis of BI in individuals with cirrhosis[9-13]and without cirrhosis[14-16].Since 2014,two meta-analyses have been published on the diagnostic value of PCT for SBP and BI in patients with cirrhosis[17,18].Other related studies have been conducted since then[10-12,19-33].Serum presepsin has recently emerged as a promising biomarker for diagnosing BI.This biomarker is the N-terminal fraction protein of the soluble CD14 g-negative bacterial lipopolysaccharide–lipopolysaccharide binding protein(sCD14-LPS-LBP)complex,which is cleaved by inflammatory serum protease in response to BI[34].Presepsin levels increase within 2 hours and peaks in 3 hours[35].This is useful for detecting BI since presepsin levels increase earlier than serum Our systematic review and meta-analysis was performed with adherence to PRISMA guidelines[37].展开更多
In this review,we explore the application of next-generation sequencing in liver cancer research,highlighting its potential in modern oncology.Liver cancer,particularly hepatocellular carcinoma,is driven by a complex ...In this review,we explore the application of next-generation sequencing in liver cancer research,highlighting its potential in modern oncology.Liver cancer,particularly hepatocellular carcinoma,is driven by a complex interplay of genetic,epigenetic,and environmental factors.Key genetic alterations,such as mutations in TERT,TP53,and CTNNB1,alongside epigenetic modifications such as DNA methylation and histone remodeling,disrupt regulatory pathways and promote tumorigenesis.Environmental factors,including viral infections,alcohol consum-ption,and metabolic disorders such as nonalcoholic fatty liver disease,enhance hepatocarcinogenesis.The tumor microenvironment plays a pivotal role in liver cancer progression and therapy resistance,with immune cell infiltration,fibrosis,and angiogenesis supporting cancer cell survival.Advances in immune check-point inhibitors and chimeric antigen receptor T-cell therapies have shown po-tential,but the unique immunosuppressive milieu in liver cancer presents challenges.Dysregulation in pathways such as Wnt/β-catenin underscores the need for targeted therapeutic strategies.Next-generation sequencing is accele-rating the identification of genetic and epigenetic alterations,enabling more precise diagnosis and personalized treatment plans.A deeper understanding of these molecular mechanisms is essential for advancing early detection and developing effective therapies against liver cancer.展开更多
Semantic communication(SemCom)aims to achieve high-fidelity information delivery under low communication consumption by only guaranteeing semantic accuracy.Nevertheless,semantic communication still suffers from unexpe...Semantic communication(SemCom)aims to achieve high-fidelity information delivery under low communication consumption by only guaranteeing semantic accuracy.Nevertheless,semantic communication still suffers from unexpected channel volatility and thus developing a re-transmission mechanism(e.g.,hybrid automatic repeat request[HARQ])becomes indispensable.In that regard,instead of discarding previously transmitted information,the incremental knowledge-based HARQ(IK-HARQ)is deemed as a more effective mechanism that could sufficiently utilize the information semantics.However,considering the possible existence of semantic ambiguity in image transmission,a simple bit-level cyclic redundancy check(CRC)might compromise the performance of IK-HARQ.Therefore,there emerges a strong incentive to revolutionize the CRC mechanism,thus more effectively reaping the benefits of both SemCom and HARQ.In this paper,built on top of swin transformer-based joint source-channel coding(JSCC)and IK-HARQ,we propose a semantic image transmission framework SC-TDA-HARQ.In particular,different from the conventional CRC,we introduce a topological data analysis(TDA)-based error detection method,which capably digs out the inner topological and geometric information of images,to capture semantic information and determine the necessity for re-transmission.Extensive numerical results validate the effectiveness and efficiency of the proposed SC-TDA-HARQ framework,especially under the limited bandwidth condition,and manifest the superiority of TDA-based error detection method in image transmission.展开更多
The results of comparative theoretical analyzes of the behavior of internal low-frequency noises, signal-to-noise ratio and sensitivity to DNA molecules for EIS and ISFET based nanosize biosensors are presented. It is...The results of comparative theoretical analyzes of the behavior of internal low-frequency noises, signal-to-noise ratio and sensitivity to DNA molecules for EIS and ISFET based nanosize biosensors are presented. It is shown that EIS biosensor is more sensitive to the presence of DNA molecules in aqueous solution than ISFET sensor. Internal electrical noises level decreases with the increase of concentration of DNA molecules in aqueous solution. In the frequency range 10−3 - 103 Hz noises level for EIS sensor about in three orders is higher than for ISFET sensor. In the other hand, signal-to-noise ratio for capacitive EIS biosensor is much higher than for ISFET sensor.展开更多
Factors influencing the signal-to-noise ratio (SNR) of lensless ghost interference with thermal incoherent light are investigated. Our result shows that the SNR of lensless ghost interference is related to the trans...Factors influencing the signal-to-noise ratio (SNR) of lensless ghost interference with thermal incoherent light are investigated. Our result shows that the SNR of lensless ghost interference is related to the transverse length of the object, the position of the object in the imaging system and the transverse size of the light source. Furthermore, the effects of these factors on the SNR are discussed in detail by numerical simulations.展开更多
Efficiently performing high-resolution direction of arrival(DOA)estimation under low signal-to-noise ratio(SNR)conditions has always been a challenge task in the literatures.Obvi-ously,in order to address this problem...Efficiently performing high-resolution direction of arrival(DOA)estimation under low signal-to-noise ratio(SNR)conditions has always been a challenge task in the literatures.Obvi-ously,in order to address this problem,the key is how to mine or reveal as much DOA related in-formation as possible from the degraded array outputs.However,it is certain that there is no per-fect solution for low SNR DOA estimation designed in the way of winner-takes-all.Therefore,this paper proposes to explore in depth the complementary DOA related information that exists in spa-tial spectrums acquired by different basic DOA estimators.Specifically,these basic spatial spec-trums are employed as the input of multi-source information fusion model.And the multi-source in-formation fusion model is composed of three heterogeneous meta learning machines,namely neural networks(NN),support vector machine(SVM),and random forests(RF).The final meta-spec-trum can be obtained by performing a final decision-making method.Experimental results illus-trate that the proposed information fusion based DOA estimation method can really make full use of the complementary information in the spatial spectrums obtained by different basic DOA estim-ators.Even under low SNR conditions,promising DOA estimation performance can be achieved.展开更多
基金This work was supported by the National Natural Science Foundation of China (No. 41074104) and Open Fund of Key Laboratory of Exploration Technologies for Oil and Gas Resources (Yangtze University), Ministry of Education (No. K2013-05).
文摘Seismic data with high signal-to-noise ratios(SNRs) are useful in reservoir exploration. To obtain high SNR seismic data, significant effort is required to achieve noise attenuation in seismic data processing, which is costly in materials, and human and financial resources. We introduce a method for improving the SNR of seismic data. The SNR is calculated by using the frequency domain method. Furthermore, we optimize and discuss the critical parameters and calculation procedure. We applied the proposed method on real data and found that the SNR is high in the seismic marker and low in the fracture zone. Consequently, this can be used to extract detailed information about fracture zones that are inferred by structural analysis but not observed in conventional seismic data.
文摘Based on chaotic oscillator system, this paper proposes a novel method on high frequency low signal- to-noise ratio BPSK( Binary Phase Shift Keying) signal detection. Chaotic oscillator system is a typical non-lin- ear system which is sensitive to periodic signals and immune to noise at the same time. Those properties make it possible to detect low signal-to-noise ratio signals. The BPSK signal is a common signal type which is widely used in modern communication. Starting from the analysis of advantages of chaotic, os~.illator system and signal features of the BPSK signal, we put forward a unique method that can detect low signar-to-noise ratio BPSK sig- nals with high frequency. The simulation results show that the novel method can dclct.t low signal-to-noise ratio BPSK signals with frequency in an order of magnitude of l0s Hz, and the input Signal-to-Noise Ratio threshold can be -20 dB.
基金financially supported by the National Key R&D Program of China(No.2018YFC1504200)the LU JIAXI International Team Program from the KC Wong Education Foundation and CAS(No.GJTD-2018-12)National Natural Science Foundation of China(Nos.41661164035 and 41704066).
文摘Template matching is a useful method to detect seismic events through waveform similarity between two signals.The traditional template matching method works well in detecting small tectonic earthquakes.However,the method has some difficulty when the signals have relatively low signal-to-noise ratios(SNRs)and simple shapes,e.g.a sinusoidal function.In this study,we modify the traditional template matching approach for this situation.We first construct a virtual three-component seismic station using vertical-component waveforms recorded by three stations.Next,we select a template event from the virtual station,and apply the traditional template matching.We then verify this method by detecting icequakes with simple waveforms on the Urumqi Glacier No.1 and compare the results with those from the short-term-averages over long-term-average(STA/LTA),the REST method,and traditional template matching method.It can be concluded that the modified template matching method using virtual stations has some advantages for seismic data with low SNRs.
文摘Background: The signal-to-noise ratio (SNR) is recognized as an index of measurements reproducibility. We derive the maximum likelihood estimators of SNR and discuss confidence interval construction on the difference between two correlated SNRs when the readings are from bivariate normal and bivariate lognormal distribution. We use the Pearsons system of curves to approximate the difference between the two estimates and use the bootstrap methods to validate the approximate distributions of the statistic of interest. Methods: The paper uses the delta method to find the first four central moments, and hence the skewness and kurtosis which are important in the determination of the parameters of the Pearsons distribution. Results: The approach is illustrated in two examples;one from veterinary microbiology and food safety data and the other on data from clinical medicine. We derived the four central moments of the target statistics, together with the bootstrap method to evaluate the parameters of Pearsons distribution. The fitted Pearsons curves of Types I and II were recommended based on the available data. The R-codes are also provided to be readily used by the readers.
文摘Food safety problems caused by excessive nitrite addition have been frequently reported and the detection of nitrite in food is particularly important. The standing time during the pretreatment of primary sample has a great influence on the concentration of nitrite tested by spectrophotometric method. In this context, three kinds of food samples are prepared, including canned mustard, canned fish and home-made pickled water. A series of standing times are placed during the sample pretreatments and the corresponding nitrite contents in these samples are detected by spectrophotometric method based on N-ethylenediamine dihydrochloride. This study aims to find out a reasonable standing time during the pretreatment of food sample, providing influence factor for precise detection of nitrite.
基金Project supported by the National Key Research and Development Program of China(Grant No.2017YFA0304203)the Chang Jiang Scholars and Innovative Research Team in the University of the Ministry of Education of China(Grant No.IRT13076)+2 种基金the National Natural Science Foundation of China(Grant Nos.91436108,61378014,61675121,61705123,and 61722507)the Fund for Shanxi“1331 Project”Key Subjects Construction,Chinathe Foundation for Outstanding Young Scholars of Shanxi Province,China(Grant No.201601D021001)
文摘We report a method of high-sensitively detecting the weak signal in photoassociation (PA) spectra of ultracold NaCs molecules by phase sensitive-demodulated trap-loss spectra of Na atoms from a photomultiplier tube. We find that the signal-to-noise ratio (SNR) of the PA spectra is strongly dependent on the integration time and the sensitivity of the lock-in amplifier, and our results show reasonable agreement with the theoretical analyses of the SNR with the demodulation parameters. Meanwhile, we investigate the effect of the interaction time of the PA laser with the colliding Na-Cs atom pairs on the SNR of the PA spectra. The atom loss rate is dependent on both the PA-induced atom loss and the loading of the MOT. The high-sensitive detection of the excited ultracold NaCs molecules lays a solid foundation for further study of the formation and application of ultracold NaCs molecules.
基金Project supported by the National Key Research and Development Program of China(Grant No.2016YFA0301204)the National Natural Science Foundation of China(Grant No.11874350)Key Research Program of the Chinese Academy of Sciences(Grant Nos.XDPB22 and ZDBS-LY-SLH004).
文摘Raman spectroscopy has been widely used to characterize the physical properties of two-dimensional materials(2DMs).The signal-to-noise ratio(SNR or S/N ratio)of Raman signal usually serves as an important indicator to evaluate the instrumental performance rather than Raman intensity itself.Multichannel detectors with outstanding sensitivity,rapid acquisition speed and low noise level have been widely equipped in Raman instruments for the measurement of Raman signal.In this mini-review,we first introduce the recent advances of Raman spectroscopy of 2DMs.Then we take the most commonly used CCD detector and IGA array detector as examples to overview the various noise sources in Raman measurements and analyze their potential influences on SNR of Raman signal in experiments.This overview can contribute to a better understanding on the SNR of Raman signal and the performance of multichannel detector for numerous researchers and instrumental design for industry,as well as offer practical strategies for improving spectral quality in routine measurement.
文摘Lung cancer continues to be a leading cause of cancer-related deaths worldwide,emphasizing the critical need for improved diagnostic techniques.Early detection of lung tumors significantly increases the chances of successful treatment and survival.However,current diagnostic methods often fail to detect tumors at an early stage or to accurately pinpoint their location within the lung tissue.Single-model deep learning technologies for lung cancer detection,while beneficial,cannot capture the full range of features present in medical imaging data,leading to incomplete or inaccurate detection.Furthermore,it may not be robust enough to handle the wide variability in medical images due to different imaging conditions,patient anatomy,and tumor characteristics.To overcome these disadvantages,dual-model or multi-model approaches can be employed.This research focuses on enhancing the detection of lung cancer by utilizing a combination of two learning models:a Convolutional Neural Network(CNN)for categorization and the You Only Look Once(YOLOv8)architecture for real-time identification and pinpointing of tumors.CNNs automatically learn to extract hierarchical features from raw image data,capturing patterns such as edges,textures,and complex structures that are crucial for identifying lung cancer.YOLOv8 incorporates multiscale feature extraction,enabling the detection of tumors of varying sizes and scales within a single image.This is particularly beneficial for identifying small or irregularly shaped tumors that may be challenging to detect.Furthermore,through the utilization of cutting-edge data augmentation methods,such as Deep Convolutional Generative Adversarial Networks(DCGAN),the suggested approach can handle the issue of limited data and boost the models’ability to learn from diverse and comprehensive datasets.The combined method not only improved accuracy and localization but also ensured efficient real-time processing,which is crucial for practical clinical applications.The CNN achieved an accuracy of 97.67%in classifying lung tissues into healthy and cancerous categories.The YOLOv8 model achieved an Intersection over Union(IoU)score of 0.85 for tumor localization,reflecting high precision in detecting and marking tumor boundaries within the images.Finally,the incorporation of synthetic images generated by DCGAN led to a 10%improvement in both the CNN classification accuracy and YOLOv8 detection performance.
文摘Security and safety remain paramount concerns for both governments and individuals worldwide.In today’s context,the frequency of crimes and terrorist attacks is alarmingly increasing,becoming increasingly intolerable to society.Consequently,there is a pressing need for swift identification of potential threats to preemptively alert law enforcement and security forces,thereby preventing potential attacks or violent incidents.Recent advancements in big data analytics and deep learning have significantly enhanced the capabilities of computer vision in object detection,particularly in identifying firearms.This paper introduces a novel automatic firearm detection surveillance system,utilizing a one-stage detection approach named MARIE(Mechanism for Realtime Identification of Firearms).MARIE incorporates the Single Shot Multibox Detector(SSD)model,which has been specifically optimized to balance the speed-accuracy trade-off critical in firearm detection applications.The SSD model was further refined by integrating MobileNetV2 and InceptionV2 architectures for superior feature extraction capabilities.The experimental results demonstrate that this modified SSD configuration provides highly satisfactory performance,surpassing existing methods trained on the same dataset in terms of the critical speedaccuracy trade-off.Through these innovations,MARIE sets a new standard in surveillance technology,offering a robust solution to enhance public safety effectively.
基金the“Intelligent Recognition Industry Service Center”as part of the Featured Areas Research Center Program under the Higher Education Sprout Project by the Ministry of Education(MOE)in Taiwan,and the National Science and Technology Council,Taiwan,under grants 113-2221-E-224-041 and 113-2622-E-224-002.Additionally,partial support was provided by Isuzu Optics Corporation.
文摘Liver cancer remains a leading cause of mortality worldwide,and precise diagnostic tools are essential for effective treatment planning.Liver Tumors(LTs)vary significantly in size,shape,and location,and can present with tissues of similar intensities,making automatically segmenting and classifying LTs from abdominal tomography images crucial and challenging.This review examines recent advancements in Liver Segmentation(LS)and Tumor Segmentation(TS)algorithms,highlighting their strengths and limitations regarding precision,automation,and resilience.Performance metrics are utilized to assess key detection algorithms and analytical methods,emphasizing their effectiveness and relevance in clinical contexts.The review also addresses ongoing challenges in liver tumor segmentation and identification,such as managing high variability in patient data and ensuring robustness across different imaging conditions.It suggests directions for future research,with insights into technological advancements that can enhance surgical planning and diagnostic accuracy by comparing popular methods.This paper contributes to a comprehensive understanding of current liver tumor detection techniques,provides a roadmap for future innovations,and improves diagnostic and therapeutic outcomes for liver cancer by integrating recent progress with remaining challenges.
文摘A measurement system for the scattering characteristics of warhead fragments based on high-speed imaging systems offers advantages such as simple deployment,flexible maneuverability,and high spatiotemporal resolution,enabling the acquisition of full-process data of the fragment scattering process.However,mismatches between camera frame rates and target velocities can lead to long motion blur tails of high-speed fragment targets,resulting in low signal-to-noise ratios and rendering conventional detection algorithms ineffective in dynamic strong interference testing environments.In this study,we propose a detection framework centered on dynamic strong interference disturbance signal separation and suppression.We introduce a mixture Gaussian model constrained under a joint spatialtemporal-transform domain Dirichlet process,combined with total variation regularization to achieve disturbance signal suppression.Experimental results demonstrate that the proposed disturbance suppression method can be integrated with certain conventional motion target detection tasks,enabling adaptation to real-world data to a certain extent.Moreover,we provide a specific implementation of this process,which achieves a detection rate close to 100%with an approximate 0%false alarm rate in multiple sets of real target field test data.This research effectively advances the development of the field of damage parameter testing.
文摘BACKGROUND Diagnosing bacterial infections(BI)in patients with cirrhosis can be challenging because of unclear symptoms,low diagnostic accuracy,and lengthy culture testing times.Various biomarkers have been studied,including serum procal-citonin(PCT)and presepsin.However,the diagnostic performance of these markers remains unclear,requiring further informative studies to ascertain their diagnostic value.AIM To evaluate the pooled diagnostic performance of PCT and presepsin in detecting BI among patients with cirrhosis.INTRODUCTION Bacterial infections(BI)commonly occur in patients with cirrhosis,resulting in poor outcomes,including the development of cirrhotic complications,septic shock,acute-on-chronic liver failure(ACLF),multiple organ failures,and mortality[1,2].BI is observed in 20%-30%of hospitalized patients,with and without ACLF[3].Patients with cirrhosis are susceptible to BI because of internal and external factors.The major internal factors are changes in gut microbial composition and function,bacterial translocation,and cirrhosis-associated immune dysfunction syndrome[4,5].External factors include alcohol use,proton-pump inhibitor use,frailty,readmission,and invasive procedures.Spontaneous bacterial peritonitis(SBP),urinary tract infection,pneumonia,and primary bacteremia are the common BIs in hospit-alized patients with cirrhosis[6].Early diagnosis and adequate empirical antibiotic therapy are two critical factors that improve the prognosis of BI in patients with cirrhosis.However,early detection of BI in cirrhosis is challenging due to subtle clinical signs and symptoms,low sensitivity and specificity of systemic inflammatory response syndrome criteria,and low sensitivity of bacterial cultures.Thus,effective biomarkers need to be identified for the early detection of BI.Several biomarkers have been evaluated,but their efficacy in detecting BI is unclear.Procalcitonin(PCT)is a precursor of the hormone calcitonin,which is secreted by parafollicular cells of the thyroid gland[7].In the presence of BI,PCT gene expression increases in extrathyroidal tissues,causing a subsequent increase in serum PCT level[8].Changes in serum PCT are detectable as early as 4 hours after infection onset and peaks between 8 and 24 hours,making it a valuable diagnostic biomarker for BI.Several studies have demonstrated the favorable diagnostic accuracy of PCT in the diagnosis of BI in individuals with cirrhosis[9-13]and without cirrhosis[14-16].Since 2014,two meta-analyses have been published on the diagnostic value of PCT for SBP and BI in patients with cirrhosis[17,18].Other related studies have been conducted since then[10-12,19-33].Serum presepsin has recently emerged as a promising biomarker for diagnosing BI.This biomarker is the N-terminal fraction protein of the soluble CD14 g-negative bacterial lipopolysaccharide–lipopolysaccharide binding protein(sCD14-LPS-LBP)complex,which is cleaved by inflammatory serum protease in response to BI[34].Presepsin levels increase within 2 hours and peaks in 3 hours[35].This is useful for detecting BI since presepsin levels increase earlier than serum Our systematic review and meta-analysis was performed with adherence to PRISMA guidelines[37].
文摘In this review,we explore the application of next-generation sequencing in liver cancer research,highlighting its potential in modern oncology.Liver cancer,particularly hepatocellular carcinoma,is driven by a complex interplay of genetic,epigenetic,and environmental factors.Key genetic alterations,such as mutations in TERT,TP53,and CTNNB1,alongside epigenetic modifications such as DNA methylation and histone remodeling,disrupt regulatory pathways and promote tumorigenesis.Environmental factors,including viral infections,alcohol consum-ption,and metabolic disorders such as nonalcoholic fatty liver disease,enhance hepatocarcinogenesis.The tumor microenvironment plays a pivotal role in liver cancer progression and therapy resistance,with immune cell infiltration,fibrosis,and angiogenesis supporting cancer cell survival.Advances in immune check-point inhibitors and chimeric antigen receptor T-cell therapies have shown po-tential,but the unique immunosuppressive milieu in liver cancer presents challenges.Dysregulation in pathways such as Wnt/β-catenin underscores the need for targeted therapeutic strategies.Next-generation sequencing is accele-rating the identification of genetic and epigenetic alterations,enabling more precise diagnosis and personalized treatment plans.A deeper understanding of these molecular mechanisms is essential for advancing early detection and developing effective therapies against liver cancer.
基金supported in part by the National Key Research and Development Program of China under Grant 2024YFE0200600in part by the National Natural Science Foundation of China under Grant 62071425+3 种基金in part by the Zhejiang Key Research and Development Plan under Grant 2022C01093in part by the Zhejiang Provincial Natural Science Foundation of China under Grant LR23F010005in part by the National Key Laboratory of Wireless Communications Foundation under Grant 2023KP01601in part by the Big Data and Intelligent Computing Key Lab of CQUPT under Grant BDIC-2023-B-001.
文摘Semantic communication(SemCom)aims to achieve high-fidelity information delivery under low communication consumption by only guaranteeing semantic accuracy.Nevertheless,semantic communication still suffers from unexpected channel volatility and thus developing a re-transmission mechanism(e.g.,hybrid automatic repeat request[HARQ])becomes indispensable.In that regard,instead of discarding previously transmitted information,the incremental knowledge-based HARQ(IK-HARQ)is deemed as a more effective mechanism that could sufficiently utilize the information semantics.However,considering the possible existence of semantic ambiguity in image transmission,a simple bit-level cyclic redundancy check(CRC)might compromise the performance of IK-HARQ.Therefore,there emerges a strong incentive to revolutionize the CRC mechanism,thus more effectively reaping the benefits of both SemCom and HARQ.In this paper,built on top of swin transformer-based joint source-channel coding(JSCC)and IK-HARQ,we propose a semantic image transmission framework SC-TDA-HARQ.In particular,different from the conventional CRC,we introduce a topological data analysis(TDA)-based error detection method,which capably digs out the inner topological and geometric information of images,to capture semantic information and determine the necessity for re-transmission.Extensive numerical results validate the effectiveness and efficiency of the proposed SC-TDA-HARQ framework,especially under the limited bandwidth condition,and manifest the superiority of TDA-based error detection method in image transmission.
文摘The results of comparative theoretical analyzes of the behavior of internal low-frequency noises, signal-to-noise ratio and sensitivity to DNA molecules for EIS and ISFET based nanosize biosensors are presented. It is shown that EIS biosensor is more sensitive to the presence of DNA molecules in aqueous solution than ISFET sensor. Internal electrical noises level decreases with the increase of concentration of DNA molecules in aqueous solution. In the frequency range 10−3 - 103 Hz noises level for EIS sensor about in three orders is higher than for ISFET sensor. In the other hand, signal-to-noise ratio for capacitive EIS biosensor is much higher than for ISFET sensor.
基金supported by the National Natural Science Foundation of China (Grant Nos. 11074307 and 10774192)the Opening Research Foundation of State Key Laboratory of Precision Spectroscopy,ECNU
文摘Factors influencing the signal-to-noise ratio (SNR) of lensless ghost interference with thermal incoherent light are investigated. Our result shows that the SNR of lensless ghost interference is related to the transverse length of the object, the position of the object in the imaging system and the transverse size of the light source. Furthermore, the effects of these factors on the SNR are discussed in detail by numerical simulations.
基金the National Natural Science Foundation of China(Nos.11774073 and 51279033).
文摘Efficiently performing high-resolution direction of arrival(DOA)estimation under low signal-to-noise ratio(SNR)conditions has always been a challenge task in the literatures.Obvi-ously,in order to address this problem,the key is how to mine or reveal as much DOA related in-formation as possible from the degraded array outputs.However,it is certain that there is no per-fect solution for low SNR DOA estimation designed in the way of winner-takes-all.Therefore,this paper proposes to explore in depth the complementary DOA related information that exists in spa-tial spectrums acquired by different basic DOA estimators.Specifically,these basic spatial spec-trums are employed as the input of multi-source information fusion model.And the multi-source in-formation fusion model is composed of three heterogeneous meta learning machines,namely neural networks(NN),support vector machine(SVM),and random forests(RF).The final meta-spec-trum can be obtained by performing a final decision-making method.Experimental results illus-trate that the proposed information fusion based DOA estimation method can really make full use of the complementary information in the spatial spectrums obtained by different basic DOA estim-ators.Even under low SNR conditions,promising DOA estimation performance can be achieved.