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题名一种定氧加铝模型控制系统
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作者
刘星
方康玲
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机构
武汉科技大学
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出处
《微计算机信息》
北大核心
2006年第06S期76-78,共3页
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基金
湖北省自然科学基金(2004ABA044)资助
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文摘
本文介绍了一种定氧加铝自动控制系统。本系统采用光电传感器作为反馈信号,改变了以往采用变频器调节电机速度的开环控制方式,并通过算法软件建立模型,自动控制加铝量,达到减少钢水中的杂质,提高钢产品质量的目的。系统结构已申请实用新型专利。
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关键词
定氧加铝
喂线控制
模型
MCGS
自动控制系统
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Keywords
determination of oxygen by feeding aluminium
Cored-Wire Injection Technology
Model
MCGS
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分类号
TP273
[自动化与计算机技术—检测技术与自动化装置]
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题名脉冲色谱法测定铝钼合金中的氧
被引量：3
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作者
宋忠训
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机构
天津冶金材料研究所
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出处
《分析试验室》
CAS
CSCD
北大核心
1993年第6期80-82,共3页
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文摘
本文提出了用脉冲色谱法测定铝钼合金中的氧,对取样和氧的提取条件进行了详细的研究,获得满意结果,方法精度为5.1%。
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关键词
脉冲色谱法
铝钼合金
氧
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Keywords
Impulse heating-gas chromatography
aluminium molybdenum alloys
oxygen determination
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分类号
TG146.21
[金属学及工艺—金属材料]
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题名基质金属蛋白酶-9抑制剂对犬体外循环肺损伤的影响
被引量：4
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作者
龚文辉
葛圣林
张成鑫
张胜权
冯俊波
张雷
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机构
安徽医科大学第二附属医院心胸外科
安徽医科大学第一附属医院心血管外科
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出处
《中国胸心血管外科临床杂志》
CAS
2010年第1期36-40,共5页
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基金
安徽省自然科学基金资助项目(070413070)~~
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文摘
目的研究外源性基质金属蛋白酶-9(matrix metalloproteinases-9,MMP-9)抑制剂多西环素(Doxycycline)对体外循环(CPB)引起肺损伤的保护作用。方法将20只健康杂种幼犬(体重10～12kg),采用随机数字表法随机分为对照组(n=10)和实验组(n=10);对照组:CPB前后不采取任何肺保护措施;实验组:CPB术前3d每天饲料拌食多西环素(30mg/kg体重)。采用酶联免疫吸附(ELISA)法检测血浆MMP-9浓度;监测两组犬血流动力学和呼吸参数,计算术前和术后肺泡-动脉氧分压差(A-aDO2)和呼吸指数(RI);比色法测定支气管肺泡灌洗液(BALF)髓过氧化物酶(MPO)活性;考马斯亮蓝G-250法测定BALF总蛋白。CPB后,在光学显微镜和电子显微镜下观察肺组织形态学改变;计算肺组织干湿重系数(W/D)。结果两组犬血浆MMP-9浓度随CPB时间延长而显著增高,CBP150min和270min时实验组血浆中MMP-9含量较对照组显著下降(9.45±5.29ng/mlvs.18.66±5.90ng/ml,t=3.664,P=0.005;16.63±2.90ng/mlvs.26.17±5.96ng/ml,t=5.216,P=0.001)。实验组MPO活性,BALF中总蛋白浓度,肺组织W/D,术后A-aDO2和RI均较对照组均明显减低,差异有统计学意义(t=5.622,P=0.000;t=5.081,P=0.001;t=2.266,P=0.050;t=4.927,P=0.001;t=6.679,P=0.000)。肺组织病理和电子显微镜显示实验组损伤明显减轻。结论多西环素通过抑制MMP-9的分泌,降低细胞基底膜的降解,减轻肺泡白细胞浸润和肺水肿,可起到对肺的保护作用。
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关键词
体外循环
急性肺损伤
基质金属蛋白酶
多西环素
肺保护
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Keywords
Objective To study the protective effect of exogenous matrix metalloproteinases-9（MMP-9） inhibitor Doxycycline against lung injury during cardiopulmonary bypass（CPB） in dogs. Methods Twenty healthy mongrel puppies（weighed 10 -12 kg） were divided into control group （n=10） and experimental group（n=10） with random number table. In control group, no measure was taken to protect lung before and after CPB. In experimental group, the feeding food was mixed with Doxycycline （30 mg/kg, body weight） daily for three days before operation. Enzyme-linked immunosorbent assay（ELISA） was used to measure the plasma concentration of MMP-9. Hemodynamic and respiratory parameters in two groups were monitored. The preoperative and postoperative alveolar-arterial oxygen partial pressure difference （A-aDO2） and respiratory index（RI） were calculated. The myeloperoxidase（MPO）activity of bronchoalveolar lavage fluid（BALF）was determined by colorimetry. The total protein of BALF was measured by Coomassie Brillian...更多t Blue G-250. After CPB, light microscope and electronic microscope were used to observe the morphological changes of lung tissue. The dry to wet weight index（W/D） was calculated. Results In both groups, the plasma concentrations of MMP-9 increased significantly as the time of CPB prolonged. The plasma MMP-9 at 150 min and 270 min after CPB in experimental group decreased significantly than those in control group （9.45±5.29 ng/ml vs. 18.66±5.90 ng/ml, t=3.664, P=0.005
16.63±2.90 ng/ml vs. 26.17±5.96 ng/ml, t=5.216, P= 0.001）. MPO activity, total protein of BALF, W/D, postoperative A-aDO2 and RI in experimental group decreased significantly than those in control group. There were significant differences between two groups（t=5.622, P=0.000
t=5.081, P=0.001
t=2.266, P=0.050
t=4.927, P=0.001
t=6.679,P=0.000）. The lung histopathology and electronic microscope showed that the lung injury reduced significantly. Conclusion Doxycycline plays a role in lung protection by inhibiting the secretion of MMP-9, reducing the degradation of cell basement membrane, pulmonary neutrophil infiltration and pulmonary edema. 还原 Objective To study the protective effect of exogenous matrix metalloproteinases-9（MMP-9） inhibitor Doxycycline against lung injury during cardiopulmonary bypass（CPB） in dogs. Methods Twenty healthy mongrel puppies（weighed 10 -12 kg） were divided into control group （n=10） and experimental group（n=10） with random number table. In control group, no measure was taken to protect lung before and after CPB. In experimental group, the feeding food was mixed with Doxycycline （30 mg/kg, body weight） daily for three days before operation. Enzyme-linked immunosorbent assay（ELISA） was used to measure the plasma concentration of MMP-9. Hemodynamic and respiratory parameters in two groups were monitored. The preoperative and postoperative alveolar-arterial oxygen partial pressure difference （A-aDO2） and respiratory index（RI） were calculated. The myeloperoxidase（MPO）activity of bronchoalveolar lavage fluid（BALF）was determined by colorimetry. The total protein of BALF was measured by Coomassie Brillian...更多t Blue G-250. After CPB, light microscope and electronic microscope were used to observe the morphological changes of lung tissue. The dry to wet weight index（W/D） was calculated. Results In both groups, the plasma concentrations of MMP-9 increased significantly as the time of CPB prolonged. The plasma MMP-9 at 150 min and 270 min after CPB in experimental group decreased significantly than those in control group （9.45±5.29 ng/ml vs. 18.66±5.90 ng/ml, t=3.664, P=0.005
16.63±2.90 ng/ml vs. 26.17±5.96 ng/ml, t=5.216, P= 0.001）. MPO activity, total protein of BALF, W/D, postoperative A-aDO2 and RI in experimental group decreased significantly than those in control group. There were significant differences between two groups（t=5.622, P=0.000
t=5.081, P=0.001
t=2.266, P=0.050
t=4.927, P=0.001
t=6.679,P=0.000）. The lung histopathology and electronic microscope showed that the lung injury reduced significantly. Conclusion Doxycycline plays a role in lung protection by inhibiting the secretion of MMP-9, reducing the degradation of cell basement membrane, pulmonary neutrophil infiltration and pulmonary edema. 还原Cardiopulmonary bypass
Acute lung injury
Matrix metalloproteinase
Doxycycline
Lung protection
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分类号
R654.1
[医药卫生—外科学]
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