In order to improve the fire resistance,water resistance and wear resistance of ordinary plywood products in the wood processing industry,three composite structures of plywood products S1,S2 and S3 were designed in th...In order to improve the fire resistance,water resistance and wear resistance of ordinary plywood products in the wood processing industry,three composite structures of plywood products S1,S2 and S3 were designed in this paper,and a reasonable production process was proposed.Through the physical and mechanical properties and fire resistance testing and technical and economic analysis,the applicability of composite plywood was evaluated.The results of the study showed that the physical mechanics of the three kinds of composite structure plywood met the standard requirements,and their fire resistance was far better than that of ordinary plywood.Among them,the S1 structural board had the best overall physical and mechanical properties.The S3 structural board showed the best fire resistance,which was about 1.9 times more than that of ordinary plywood,and the added cost was the lowest.The thin cork board added to the S2 structural board had poor fire performance since the air in the cork board cavities had a certain combustion-supporting effect,which inhibited the fire resistance of high-pressure laminate(HPL)layer.Moreover,the additional cost of the S2 board was the highest,and its comprehensive performance was the worst.The S3 structural plywood product composed of HPL fireproof board with a thickness of about 1 mm in the surface layer and ordinary plywood with a thickness of about 12 mm in the core layer was the most cost-effective product,which could meet the needs of various fields such as construction,home furnishing,decoration and transportation.展开更多
This paper presents a methodology driven by database constraints for designing and developing(database)software applications.Much needed and with excellent results,this paradigm guarantees the highest possible quality...This paper presents a methodology driven by database constraints for designing and developing(database)software applications.Much needed and with excellent results,this paradigm guarantees the highest possible quality of the managed data.The proposed methodology is illustrated with an easy to understand,yet complex medium-sized genealogy software application driven by more than 200 database constraints,which fully meets such expectations.展开更多
The Three Gorges Project (TGP for short) is the key project to train and develop the Yangtze River of China,with multi-objects of flood defence,electricity generation,shipping,etc.However,sediment plays an important r...The Three Gorges Project (TGP for short) is the key project to train and develop the Yangtze River of China,with multi-objects of flood defence,electricity generation,shipping,etc.However,sediment plays an important role in beth constructing of engineering and exerting efficiency of TGP.Special attention,there- fore,has been paid to sediment problem of TGP since the very beginning of this engineering's pregnancy.Up to now,much observed data and fruitful researches about TGP have come into being,and a sci...展开更多
A newly emerging design pattern, named as adaptable design (AD), which aims at developing products that are adaptable from design to post-life cycle, is discussed. AD consists of four main phases: product modeling,...A newly emerging design pattern, named as adaptable design (AD), which aims at developing products that are adaptable from design to post-life cycle, is discussed. AD consists of four main phases: product modeling, design platform, specific design and product redesign. A new process-based design data model (PDDM) is presented which is organized according to the principles of convenient knowledge extraction, data representation, layout, sharing and reuse. Based on the PDDM, a universal design platform for product family development is established, which has characters of modularity, parameter-driven, variant design, etc. The framework of the platform is also proposed as a conceptual structure and overall logical organization for generating a family of products. AD methodology is successfully applied to develop a family of tunnel boring machine (TBM) for different engineering projects, with the efficiency of our developing team being greatly increased.展开更多
In this paper we have developed a data logging and monitoring system, we validated the system by comparing the result from it with the existing one and found that the system performs slightly better than the existing ...In this paper we have developed a data logging and monitoring system, we validated the system by comparing the result from it with the existing one and found that the system performs slightly better than the existing work in the same area. This implies that the data logger and monitoring system is good and can be used to monitor solar energy variables even at the comfort of our homes. We fitted a model to the generated data and found that the meteorological variables considered accounted for 99.88% of the power output in the rainy seasons while 0.12% of the variation was not explained due to other factors. Solar panels inclined at an angle of 5° (Tilt) and facing South Pole perform optimally.展开更多
Since it takes a long time to design an aircraft, the succession to or the acquirement of knowledges and technologies is a key to provide to aircraft design high quality and productivity. This paper describes a comput...Since it takes a long time to design an aircraft, the succession to or the acquirement of knowledges and technologies is a key to provide to aircraft design high quality and productivity. This paper describes a computer support system for wing design using a new tool based on an object-oriented approach. The system is programmed in a module of objects which represent design tasks or design knowledges. The modulated program gives advantages to maintain and extend the system easily. The system provides to users a flexible support with excellent user interface which consists of mouse, menu-driven system, and window system.展开更多
This paper firstly analyzes the culture of Marquis of Haihun site and explores the cultural and creative derivatives,followed by the value of these cultural and creative derivatives of Marquis of Haihun site and the d...This paper firstly analyzes the culture of Marquis of Haihun site and explores the cultural and creative derivatives,followed by the value of these cultural and creative derivatives of Marquis of Haihun site and the design and development path of the cultural and creative derivatives of Marquis of Haihun site for the reference of relevant scholars.展开更多
Despite the global decline in the severity of the coronavirus disease 2019 (COVID-19) cases, the disease stillrepresents a major concern to the relevant scientific and medical communities. The primary concern of drug ...Despite the global decline in the severity of the coronavirus disease 2019 (COVID-19) cases, the disease stillrepresents a major concern to the relevant scientific and medical communities. The primary concern of drug scientists,virologists, and other concerned specialists in this respect is to find ready-to-use suitable and potent anticoronaviraltherapies that are broadly effective against the different species/strains of the coronaviruses in general, not only againstthe current and previous coronaviruses (e.g., the recently-appeared severe acute respiratory syndrome coronavirus 2“SARS-CoV-2”), i.e., effective antiviral agents for treatment and/or prophylaxis of any coronaviral infections, includingthose of the coming ones from the next species and strains (if any). As an expert in this field, I tried, in this up-to-dateperspective “viewpoint” article, to evaluate the suitability and applicability of using the currently-availableanticoronaviral agents for the next coronavirus diseases (COVIDs) and coronaviral pandemics, highlighting the mostimportant general guidelines that should be considered in the next pandemics from the therapeutic points of view.展开更多
Historically viewed as a niche economic sector, gaming is now projected to exceed a global annual revenue of $218.7 billion in 2024, taking advantage of recent Artificial Intelligence (AI) advances. In recent ...Historically viewed as a niche economic sector, gaming is now projected to exceed a global annual revenue of $218.7 billion in 2024, taking advantage of recent Artificial Intelligence (AI) advances. In recent years, specific AI techniques namely;Machine Learning (ML) and Reinforcement Learning (RL), have seen impressive progress and popularity. Techniques developed within these two fields are now able to analyze and learn from gameplay experiences enabling more interactive, immersive, and engaging games. While the number of ML and RL algorithms is growing, their implementations through frameworks and toolkits are also extensive too. Moreover, the game design and development community lacks a framework for informed evaluation of available RL toolkits. In this paper, we present a comprehensive survey of RL toolkits for games using a qualitative evaluation methodology.展开更多
This paper analyzes the design and implementation of a normal writing test in a senior high school. In line with theories of test evaluation, an effective writing test should try to meet the balance of the six usefuln...This paper analyzes the design and implementation of a normal writing test in a senior high school. In line with theories of test evaluation, an effective writing test should try to meet the balance of the six usefulness, which will be discussed in this paper; thereafter, pedagogical implications will be mentioned with an emphasis on how a test affects the teachers in changing their teaching approaches and motivates the learners in achieving higher goals in their writing proficiency.展开更多
Australia has developed extensive policies and guidelines for the management of its water. The City of Salisbury, located within metropolitan Adelaide, South Australia, developed rapidly through urbanisation from the ...Australia has developed extensive policies and guidelines for the management of its water. The City of Salisbury, located within metropolitan Adelaide, South Australia, developed rapidly through urbanisation from the 1970s. Water sensitive urban design principles were adopted to maximise the use of the increased rim-off generated by urbanisation and ameliorate flood risk. Managed aquifer recharge was introduced for storing remediated low-salinity stormwater by aquifer storage and recovery (ASR) in a brackish aquiter for subsequent lrngatlon. Ibis paper outlines now a municipal government has progressively adopted principles of Water Sensitive Urban Design during its development within a framework of evolving national water policies. Salisbury's success with stormwater harvesting led to the formation of a pioneering w aterbusiness that includes linking projects from nine sites to provide a non-potable supply of 5 ×10^6 m^3 year. These installations hosted a number of applied research projects addressing well configuration, water quality, reliability and economics and facilitated the evaluation of its system as a potential potable water source. The evaluation showed that while untreated stonnwater contained contaminants, subsurface storage and end-use controls were sufficient to make recovered water sale for public open space irrigation, and with chlorination acceptable lbr third pipe supplies. Drinking water quality could be achieved by adding microfiltration, disinfection with UV and chlorination. The costs that would need to be expended to achieve drinking water safety standards were found to be considerably less than the cost of establishing dual pipe distribution systems. The full cost of supply was determined to be AUD$1.57 m " for non-potable water for pubhc open space lrngatlon much cheaper than mares water, AUD $3.45 m at that time. Producing and storing potable water was found to cost AUDS1.96 to $2.24 m .展开更多
This paper compares ongoing research results on hydrologic performance to common design and crediting criteria, and recommends a change in direction from a static to a dynamic perspective to fully credit the performan...This paper compares ongoing research results on hydrologic performance to common design and crediting criteria, and recommends a change in direction from a static to a dynamic perspective to fully credit the performance of green infrastructure. Examples used in this article are primarily stormwater control measures built for research on the campus of Villanova University [1,2]. Evidence is presented demonstrating that the common practice of crediting water volume based on soil and surface storage underestimates the performance potential, and suggests that the profession move to a more dynamic approach that incorporates exfiltration and evapotranspiration. The framework for a dynamic approach is discussed, with a view to broaden our design focus by including climate, configuration and the soil surroundings. The substance of this work was presented as a keynote speech at the 2016 international Low Impact Development Conference in Beijing China [3].展开更多
ⅠKeeping step with the economic re-structuring and the policy of opening tothe outside world,marked progress hasbeen made in China’s urban constructionand great strides have been taken in cityplanning during the ten...ⅠKeeping step with the economic re-structuring and the policy of opening tothe outside world,marked progress hasbeen made in China’s urban constructionand great strides have been taken in cityplanning during the ten years and more re-cently.This is manifested in the following5 respects.A.Thanks to the展开更多
Nine new fluorine-containing drugs have been approved by the US Food and Drug Administration(FDA)in 2021,which are presented in this review article.These small molecular drugs feature aromatic fluorine,trifluoromethyl...Nine new fluorine-containing drugs have been approved by the US Food and Drug Administration(FDA)in 2021,which are presented in this review article.These small molecular drugs feature aromatic fluorine,trifluoromethyl and chlorodifluoro groups.The therapeutic areas of these fluorine-containing drugs include multiple myeloma,lymphoma,HIV,chronic heart failure,chronic myeloid leukemia,(ANCA)-associated vasculitis,migraines,von Hippel-Lindau disease,and non-small cell lung cancer.The brief biological activities and the synthetic methods have been discussed in this review for each of these nine drugs.展开更多
Thirteen new fluorine-containing drugs,which have been granted approval by the US Food and Drug Administration(FDA)in 2020,are profiled in this review.Therapeutic areas of these new fluorinated pharmaceuticals include...Thirteen new fluorine-containing drugs,which have been granted approval by the US Food and Drug Administration(FDA)in 2020,are profiled in this review.Therapeutic areas of these new fluorinated pharmaceuticals include medicines and diagnostic agents for Cushing's disease,neurofibromatosis,migraine,Alzheimer's disease,myelodysplastic syndromes,hereditary angioedema attacks,and various cancers.Molecules of these approved drugs feature aromatic fluorine(Ar-F)(11 compounds),aromatic Ar-CF_(3)(1),aliphatic CHF(1)and CF_(2)(1)groups.For each compound,we provide a spectrum of biological activity,medicinal chemistry discovery,and synthetic approaches.展开更多
For urban land development, some or all natural land uses (primarily pervious) are converted into impervious areas which lead to increases of runoff volume and peak discharge. Most of the developed countries require...For urban land development, some or all natural land uses (primarily pervious) are converted into impervious areas which lead to increases of runoff volume and peak discharge. Most of the developed countries require a zero increase in peak discharge for any land development, and the policy has been implemented for several decades. The policy of zero increase in peak discharge can be considered as historical and early stage for the low impact development (LID) and sustainable development, which is to maintain natural hydrological conditions by storing a part or all of additional runoff due to the development on site. The paper will discuss the policy, the policy implementation for individual projects and their impact on regional hydrology. The design rainfalls for sizing LID facilities that are determined in 206 weather stations in USA are smaller than design rainfalls for sizing detention basins.The zero-increase policy links to financial responsibility and sustainability for construction of urban stormwater infrastructures and for reducing urban flooding. The policy was compared with current practices of urban development in China to shine the light for solving urban stormwater problems. The connections and differences among LID practices, the zero-increase policy, and the flood control infrastructure were discussed. We promote and advocate the zero-increase policy on peak discharge for comprehensive stormwater management in China in addition to LID.展开更多
基金This work was supported by the 2020 Jiangsu Provincial Department of Science and Technology Policy Guidance Category(North Jiangsu Science and Technology Special SZ-L YG202014).
文摘In order to improve the fire resistance,water resistance and wear resistance of ordinary plywood products in the wood processing industry,three composite structures of plywood products S1,S2 and S3 were designed in this paper,and a reasonable production process was proposed.Through the physical and mechanical properties and fire resistance testing and technical and economic analysis,the applicability of composite plywood was evaluated.The results of the study showed that the physical mechanics of the three kinds of composite structure plywood met the standard requirements,and their fire resistance was far better than that of ordinary plywood.Among them,the S1 structural board had the best overall physical and mechanical properties.The S3 structural board showed the best fire resistance,which was about 1.9 times more than that of ordinary plywood,and the added cost was the lowest.The thin cork board added to the S2 structural board had poor fire performance since the air in the cork board cavities had a certain combustion-supporting effect,which inhibited the fire resistance of high-pressure laminate(HPL)layer.Moreover,the additional cost of the S2 board was the highest,and its comprehensive performance was the worst.The S3 structural plywood product composed of HPL fireproof board with a thickness of about 1 mm in the surface layer and ordinary plywood with a thickness of about 12 mm in the core layer was the most cost-effective product,which could meet the needs of various fields such as construction,home furnishing,decoration and transportation.
文摘This paper presents a methodology driven by database constraints for designing and developing(database)software applications.Much needed and with excellent results,this paradigm guarantees the highest possible quality of the managed data.The proposed methodology is illustrated with an easy to understand,yet complex medium-sized genealogy software application driven by more than 200 database constraints,which fully meets such expectations.
文摘The Three Gorges Project (TGP for short) is the key project to train and develop the Yangtze River of China,with multi-objects of flood defence,electricity generation,shipping,etc.However,sediment plays an important role in beth constructing of engineering and exerting efficiency of TGP.Special attention,there- fore,has been paid to sediment problem of TGP since the very beginning of this engineering's pregnancy.Up to now,much observed data and fruitful researches about TGP have come into being,and a sci...
文摘A newly emerging design pattern, named as adaptable design (AD), which aims at developing products that are adaptable from design to post-life cycle, is discussed. AD consists of four main phases: product modeling, design platform, specific design and product redesign. A new process-based design data model (PDDM) is presented which is organized according to the principles of convenient knowledge extraction, data representation, layout, sharing and reuse. Based on the PDDM, a universal design platform for product family development is established, which has characters of modularity, parameter-driven, variant design, etc. The framework of the platform is also proposed as a conceptual structure and overall logical organization for generating a family of products. AD methodology is successfully applied to develop a family of tunnel boring machine (TBM) for different engineering projects, with the efficiency of our developing team being greatly increased.
文摘In this paper we have developed a data logging and monitoring system, we validated the system by comparing the result from it with the existing one and found that the system performs slightly better than the existing work in the same area. This implies that the data logger and monitoring system is good and can be used to monitor solar energy variables even at the comfort of our homes. We fitted a model to the generated data and found that the meteorological variables considered accounted for 99.88% of the power output in the rainy seasons while 0.12% of the variation was not explained due to other factors. Solar panels inclined at an angle of 5° (Tilt) and facing South Pole perform optimally.
文摘Since it takes a long time to design an aircraft, the succession to or the acquirement of knowledges and technologies is a key to provide to aircraft design high quality and productivity. This paper describes a computer support system for wing design using a new tool based on an object-oriented approach. The system is programmed in a module of objects which represent design tasks or design knowledges. The modulated program gives advantages to maintain and extend the system easily. The system provides to users a flexible support with excellent user interface which consists of mouse, menu-driven system, and window system.
文摘This paper firstly analyzes the culture of Marquis of Haihun site and explores the cultural and creative derivatives,followed by the value of these cultural and creative derivatives of Marquis of Haihun site and the design and development path of the cultural and creative derivatives of Marquis of Haihun site for the reference of relevant scholars.
文摘Despite the global decline in the severity of the coronavirus disease 2019 (COVID-19) cases, the disease stillrepresents a major concern to the relevant scientific and medical communities. The primary concern of drug scientists,virologists, and other concerned specialists in this respect is to find ready-to-use suitable and potent anticoronaviraltherapies that are broadly effective against the different species/strains of the coronaviruses in general, not only againstthe current and previous coronaviruses (e.g., the recently-appeared severe acute respiratory syndrome coronavirus 2“SARS-CoV-2”), i.e., effective antiviral agents for treatment and/or prophylaxis of any coronaviral infections, includingthose of the coming ones from the next species and strains (if any). As an expert in this field, I tried, in this up-to-dateperspective “viewpoint” article, to evaluate the suitability and applicability of using the currently-availableanticoronaviral agents for the next coronavirus diseases (COVIDs) and coronaviral pandemics, highlighting the mostimportant general guidelines that should be considered in the next pandemics from the therapeutic points of view.
文摘Historically viewed as a niche economic sector, gaming is now projected to exceed a global annual revenue of $218.7 billion in 2024, taking advantage of recent Artificial Intelligence (AI) advances. In recent years, specific AI techniques namely;Machine Learning (ML) and Reinforcement Learning (RL), have seen impressive progress and popularity. Techniques developed within these two fields are now able to analyze and learn from gameplay experiences enabling more interactive, immersive, and engaging games. While the number of ML and RL algorithms is growing, their implementations through frameworks and toolkits are also extensive too. Moreover, the game design and development community lacks a framework for informed evaluation of available RL toolkits. In this paper, we present a comprehensive survey of RL toolkits for games using a qualitative evaluation methodology.
文摘This paper analyzes the design and implementation of a normal writing test in a senior high school. In line with theories of test evaluation, an effective writing test should try to meet the balance of the six usefulness, which will be discussed in this paper; thereafter, pedagogical implications will be mentioned with an emphasis on how a test affects the teachers in changing their teaching approaches and motivates the learners in achieving higher goals in their writing proficiency.
文摘Australia has developed extensive policies and guidelines for the management of its water. The City of Salisbury, located within metropolitan Adelaide, South Australia, developed rapidly through urbanisation from the 1970s. Water sensitive urban design principles were adopted to maximise the use of the increased rim-off generated by urbanisation and ameliorate flood risk. Managed aquifer recharge was introduced for storing remediated low-salinity stormwater by aquifer storage and recovery (ASR) in a brackish aquiter for subsequent lrngatlon. Ibis paper outlines now a municipal government has progressively adopted principles of Water Sensitive Urban Design during its development within a framework of evolving national water policies. Salisbury's success with stormwater harvesting led to the formation of a pioneering w aterbusiness that includes linking projects from nine sites to provide a non-potable supply of 5 ×10^6 m^3 year. These installations hosted a number of applied research projects addressing well configuration, water quality, reliability and economics and facilitated the evaluation of its system as a potential potable water source. The evaluation showed that while untreated stonnwater contained contaminants, subsurface storage and end-use controls were sufficient to make recovered water sale for public open space irrigation, and with chlorination acceptable lbr third pipe supplies. Drinking water quality could be achieved by adding microfiltration, disinfection with UV and chlorination. The costs that would need to be expended to achieve drinking water safety standards were found to be considerably less than the cost of establishing dual pipe distribution systems. The full cost of supply was determined to be AUD$1.57 m " for non-potable water for pubhc open space lrngatlon much cheaper than mares water, AUD $3.45 m at that time. Producing and storing potable water was found to cost AUDS1.96 to $2.24 m .
文摘This paper compares ongoing research results on hydrologic performance to common design and crediting criteria, and recommends a change in direction from a static to a dynamic perspective to fully credit the performance of green infrastructure. Examples used in this article are primarily stormwater control measures built for research on the campus of Villanova University [1,2]. Evidence is presented demonstrating that the common practice of crediting water volume based on soil and surface storage underestimates the performance potential, and suggests that the profession move to a more dynamic approach that incorporates exfiltration and evapotranspiration. The framework for a dynamic approach is discussed, with a view to broaden our design focus by including climate, configuration and the soil surroundings. The substance of this work was presented as a keynote speech at the 2016 international Low Impact Development Conference in Beijing China [3].
文摘ⅠKeeping step with the economic re-structuring and the policy of opening tothe outside world,marked progress hasbeen made in China’s urban constructionand great strides have been taken in cityplanning during the ten years and more re-cently.This is manifested in the following5 respects.A.Thanks to the
基金the financial support from the National Natural Science Foundation of China(No.21761132021)the Qing-Lan Project of Jiangsu Province(for Han)IKERBASQUE,Basque Foundation for Science(for Soloshonok)。
文摘Nine new fluorine-containing drugs have been approved by the US Food and Drug Administration(FDA)in 2021,which are presented in this review article.These small molecular drugs feature aromatic fluorine,trifluoromethyl and chlorodifluoro groups.The therapeutic areas of these fluorine-containing drugs include multiple myeloma,lymphoma,HIV,chronic heart failure,chronic myeloid leukemia,(ANCA)-associated vasculitis,migraines,von Hippel-Lindau disease,and non-small cell lung cancer.The brief biological activities and the synthetic methods have been discussed in this review for each of these nine drugs.
基金the financial support from the National Natural Science Foundation of China(No.21761132021)IKERBASQUE,Basque Foundation for Science.
文摘Thirteen new fluorine-containing drugs,which have been granted approval by the US Food and Drug Administration(FDA)in 2020,are profiled in this review.Therapeutic areas of these new fluorinated pharmaceuticals include medicines and diagnostic agents for Cushing's disease,neurofibromatosis,migraine,Alzheimer's disease,myelodysplastic syndromes,hereditary angioedema attacks,and various cancers.Molecules of these approved drugs feature aromatic fluorine(Ar-F)(11 compounds),aromatic Ar-CF_(3)(1),aliphatic CHF(1)and CF_(2)(1)groups.For each compound,we provide a spectrum of biological activity,medicinal chemistry discovery,and synthetic approaches.
基金The study is partially supported by the National Natural Science Foundation of China (Grant No. 51478026).
文摘For urban land development, some or all natural land uses (primarily pervious) are converted into impervious areas which lead to increases of runoff volume and peak discharge. Most of the developed countries require a zero increase in peak discharge for any land development, and the policy has been implemented for several decades. The policy of zero increase in peak discharge can be considered as historical and early stage for the low impact development (LID) and sustainable development, which is to maintain natural hydrological conditions by storing a part or all of additional runoff due to the development on site. The paper will discuss the policy, the policy implementation for individual projects and their impact on regional hydrology. The design rainfalls for sizing LID facilities that are determined in 206 weather stations in USA are smaller than design rainfalls for sizing detention basins.The zero-increase policy links to financial responsibility and sustainability for construction of urban stormwater infrastructures and for reducing urban flooding. The policy was compared with current practices of urban development in China to shine the light for solving urban stormwater problems. The connections and differences among LID practices, the zero-increase policy, and the flood control infrastructure were discussed. We promote and advocate the zero-increase policy on peak discharge for comprehensive stormwater management in China in addition to LID.