Solasodine rhamnosyl glycosides (SRGs) are chemotherapeutic agents for the treatment of cancer. SRGs in a cream formulation, CuradermBEC5, is very effective for the treatment of nonmelanoma skin cancers with excellent...Solasodine rhamnosyl glycosides (SRGs) are chemotherapeutic agents for the treatment of cancer. SRGs in a cream formulation, CuradermBEC5, is very effective for the treatment of nonmelanoma skin cancers with excellent cosmetic end results. Intralesion injection of SRGs successfully dispose of very large tumours in animals without any clinical adverse effects. The mode of action of SRGs is by apoptosis. In this study, it is shown that small to large basal cell carcinomas are effectively treated only with topical application of CuradermBEC5. Here it is reported for the first time that combination of intralesion SRG injection and topical application with CuradermBEC5 in humans reduces the treatment time period by more than half when compared with topical application as the sole treatment regime. Two intralesion injections of very low doses of SRGs rapidly and effectively remove a large melanoma on a horse. If rapid removal of large troublesome skin cancers is required then this can be achieved by intralesion and topical treatments. Intralesion or combination therapy with SRGs may have some applications for melanomas in situ such as lentigo maligna.展开更多
As one of the most popular English learning tools, the 7th edition of Oxford Advanced Learner's English-Chinese Dictionary aims to provide adequate information to satisfy learners' needs. In this article, this...As one of the most popular English learning tools, the 7th edition of Oxford Advanced Learner's English-Chinese Dictionary aims to provide adequate information to satisfy learners' needs. In this article, this latest edition is examined with re spect to two primary aspects: syntactic and semantic information based on Chan, A.C. and Y. Loong's evaluating criteria of learn er's dictionary. The focus falls on grammatical properties of nouns, verbs and adjectives, valency requirement, definitions, syn onyms and antonyms, collocations, etc. Conclusion suggests that the overall standard of this new dictionary is admirably high in terms of applicability and user-friendliness.展开更多
自Oxford Advanced Learner's Dictionary of Current English(以下简称《牛津》)和Zongman Dictionary of Contem porary English(以下简称《朗曼》)问世以来,它们在上世纪下半叶中一直风行全世界。这两本英语学习者词典的目的在...自Oxford Advanced Learner's Dictionary of Current English(以下简称《牛津》)和Zongman Dictionary of Contem porary English(以下简称《朗曼》)问世以来,它们在上世纪下半叶中一直风行全世界。这两本英语学习者词典的目的在于解决外国研习英语者所面临的特殊困难。展开更多
As a major resource and tool of language learning, learner’s dictionaries have provided sufficient information forL2 writing, which serves as a good guide of peer feedback. Hence, learner’s dictionaries are an indis...As a major resource and tool of language learning, learner’s dictionaries have provided sufficient information forL2 writing, which serves as a good guide of peer feedback. Hence, learner’s dictionaries are an indispensable partof scaffolding in the L2 writing feedback system. However, the effects of dictionary use in L2 writing have longbeen ignored either in L2 writing pedagogy or in learner lexicography. By applying the concept of “scaffolding” topeer feedback as the theoretical framework, this study first clarifies three distinct types of scaffolding informationpresented in current English learner’s dictionaries, and then makes an investigation into EFL learners’ perceptionand practical use of scaffolding information in their English writing. Results show that most EFL learners havepositive attitudes towards scaffolding information and its role in motivating effective feedback in English writing.But their practical use of such information is not satisfactory owing to their inadequate skills and knowledge ofdictionary use. This reflects a high demand of a dictionary use course in universities, which will help to raise EFLlearners’ dictionary use efficiency as well as improve English teachers’ lexicographical expertise in English writingpedagogy.展开更多
Competence in academic writing in college is a challenging as well as an engaging task for many college students. Argumentative writing and acknowledging the counterargument is one of modes that is introduced in fresh...Competence in academic writing in college is a challenging as well as an engaging task for many college students. Argumentative writing and acknowledging the counterargument is one of modes that is introduced in freshman classes; however, college students approach writing with a certain mindset. Learning to write in different modes could be exciting when taught utilizing a film or a documentary. Using a documentary, such as Devil's Playground, writing professors not only initiate interest in culture learning and cultural understanding but also motivate students to use argumentation to foster critical thinking as well as cultural understanding.展开更多
According to Cowie(2002), choosing which type of dictionary depends on"several factors, including the year of study, the level of linguistic proficiency of the users, and the nature of the study activity"(p....According to Cowie(2002), choosing which type of dictionary depends on"several factors, including the year of study, the level of linguistic proficiency of the users, and the nature of the study activity"(p. 195). After comparing the features of monolingual and bilingual learner's dictionaries, and examining the definitions and examples of three entry words(‘owe',‘deadlock'and‘pertinent') in six popular learner's dictionaries in China, we make a tentative conclusion that bilingualised dictionary is the better choice in vocabulary learning of Chinese college students as non-English majors. Some further investigations have to be conducted about the status quo of dictionary use among Chinese college students as non-English majors and their vocabulary learning strategies.展开更多
Background: Psoriasis is a chronic disease that can have significant effects on quality of life. Aim: To test whether the antineoplastic, antipathogenic plant derived secondary metabolites, solasodine glycosides, can ...Background: Psoriasis is a chronic disease that can have significant effects on quality of life. Aim: To test whether the antineoplastic, antipathogenic plant derived secondary metabolites, solasodine glycosides, can treat psoriasis. Case Presentation: We report a case of a 54-year-old French-Vietnamese male who presented with diagnosed erythematous scaly annular recalcitrant psoriasis scattered throughout his body. Method: After failing conventional treatment regimens for over 10 years the patient received a trial with a topical cream formulation PsorendBEC, containing solasodine glycosides, for his psoriasis. Result: Topical applications of PsorendBEC twice daily resulted in complete resolution of cutaneous lesions after 4 weeks of treatment with no recurrence post 1 year after therapy. Conclusion: Topical PsorendBEC therapy rapidly removes recalcitrant psoriasis with no apparent side effects.展开更多
文摘Solasodine rhamnosyl glycosides (SRGs) are chemotherapeutic agents for the treatment of cancer. SRGs in a cream formulation, CuradermBEC5, is very effective for the treatment of nonmelanoma skin cancers with excellent cosmetic end results. Intralesion injection of SRGs successfully dispose of very large tumours in animals without any clinical adverse effects. The mode of action of SRGs is by apoptosis. In this study, it is shown that small to large basal cell carcinomas are effectively treated only with topical application of CuradermBEC5. Here it is reported for the first time that combination of intralesion SRG injection and topical application with CuradermBEC5 in humans reduces the treatment time period by more than half when compared with topical application as the sole treatment regime. Two intralesion injections of very low doses of SRGs rapidly and effectively remove a large melanoma on a horse. If rapid removal of large troublesome skin cancers is required then this can be achieved by intralesion and topical treatments. Intralesion or combination therapy with SRGs may have some applications for melanomas in situ such as lentigo maligna.
文摘As one of the most popular English learning tools, the 7th edition of Oxford Advanced Learner's English-Chinese Dictionary aims to provide adequate information to satisfy learners' needs. In this article, this latest edition is examined with re spect to two primary aspects: syntactic and semantic information based on Chan, A.C. and Y. Loong's evaluating criteria of learn er's dictionary. The focus falls on grammatical properties of nouns, verbs and adjectives, valency requirement, definitions, syn onyms and antonyms, collocations, etc. Conclusion suggests that the overall standard of this new dictionary is admirably high in terms of applicability and user-friendliness.
文摘自Oxford Advanced Learner's Dictionary of Current English(以下简称《牛津》)和Zongman Dictionary of Contem porary English(以下简称《朗曼》)问世以来,它们在上世纪下半叶中一直风行全世界。这两本英语学习者词典的目的在于解决外国研习英语者所面临的特殊困难。
文摘As a major resource and tool of language learning, learner’s dictionaries have provided sufficient information forL2 writing, which serves as a good guide of peer feedback. Hence, learner’s dictionaries are an indispensable partof scaffolding in the L2 writing feedback system. However, the effects of dictionary use in L2 writing have longbeen ignored either in L2 writing pedagogy or in learner lexicography. By applying the concept of “scaffolding” topeer feedback as the theoretical framework, this study first clarifies three distinct types of scaffolding informationpresented in current English learner’s dictionaries, and then makes an investigation into EFL learners’ perceptionand practical use of scaffolding information in their English writing. Results show that most EFL learners havepositive attitudes towards scaffolding information and its role in motivating effective feedback in English writing.But their practical use of such information is not satisfactory owing to their inadequate skills and knowledge ofdictionary use. This reflects a high demand of a dictionary use course in universities, which will help to raise EFLlearners’ dictionary use efficiency as well as improve English teachers’ lexicographical expertise in English writingpedagogy.
文摘Competence in academic writing in college is a challenging as well as an engaging task for many college students. Argumentative writing and acknowledging the counterargument is one of modes that is introduced in freshman classes; however, college students approach writing with a certain mindset. Learning to write in different modes could be exciting when taught utilizing a film or a documentary. Using a documentary, such as Devil's Playground, writing professors not only initiate interest in culture learning and cultural understanding but also motivate students to use argumentation to foster critical thinking as well as cultural understanding.
文摘According to Cowie(2002), choosing which type of dictionary depends on"several factors, including the year of study, the level of linguistic proficiency of the users, and the nature of the study activity"(p. 195). After comparing the features of monolingual and bilingual learner's dictionaries, and examining the definitions and examples of three entry words(‘owe',‘deadlock'and‘pertinent') in six popular learner's dictionaries in China, we make a tentative conclusion that bilingualised dictionary is the better choice in vocabulary learning of Chinese college students as non-English majors. Some further investigations have to be conducted about the status quo of dictionary use among Chinese college students as non-English majors and their vocabulary learning strategies.
文摘Background: Psoriasis is a chronic disease that can have significant effects on quality of life. Aim: To test whether the antineoplastic, antipathogenic plant derived secondary metabolites, solasodine glycosides, can treat psoriasis. Case Presentation: We report a case of a 54-year-old French-Vietnamese male who presented with diagnosed erythematous scaly annular recalcitrant psoriasis scattered throughout his body. Method: After failing conventional treatment regimens for over 10 years the patient received a trial with a topical cream formulation PsorendBEC, containing solasodine glycosides, for his psoriasis. Result: Topical applications of PsorendBEC twice daily resulted in complete resolution of cutaneous lesions after 4 weeks of treatment with no recurrence post 1 year after therapy. Conclusion: Topical PsorendBEC therapy rapidly removes recalcitrant psoriasis with no apparent side effects.