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Clinical efficacy and significance of serum fibroblast growth factor-21 and ghrelin in the treatment of type 2 diabetes complicated with coronary heart disease with integrated traditional Chinese and western medicine
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作者 Su Gao Xue Tian +1 位作者 Wei-Na Jiang Yao Ma 《Journal of Hainan Medical University》 2018年第22期13-17,共5页
Objective: To treat the patients with type 2 diabetes mellitus complicated with coronary heart disease, to explore the clinical efficacy and mechanism of conventional western medicine combined with Yiqi Yangyin Huoxue... Objective: To treat the patients with type 2 diabetes mellitus complicated with coronary heart disease, to explore the clinical efficacy and mechanism of conventional western medicine combined with Yiqi Yangyin Huoxue herbs, and to detect the level of serum fibroblast growth factor-21 (FGF-21) and Ghrelin. Changes and significance. Methods: A randomized control method was used to collect 100 patients with type 2 diabetes mellitus complicated with coronary heart disease who were diagnosed and treated in our hospital from March 2015 to March 2018.They were randomly divided into two groups according to the random number table method: 50 patients separately. The patients in the control group were treated with conventional western medicine and basic treatment;the observation group was treated with the addition and subtraction of traditional Chinese medicine formulas on the basis of the control group;the clinical curative effect was evaluated after two months of treatment, and the treatment efficiency and scores of traditional Chinese medicine symptoms were observed in the two groups. Basic laboratory indicators were improved, and serum levels of FGF-21 and Ghrelin in patients were measured and the difference between the results of the tests was compared with the condition and efficacy. Results: After treatment, the total effective rate of the observation group (86.0%) was significantly higher than that of the control group (68.0%) (P<0.05), suggesting that the combination of Chinese and Western medicine treatment can significantly improve the clinical efficacy;before treatment,there is no difference between the two groups of Chinese medicine symptom scores (P>0.05). After treatment, the symptom scores of the two groups were significantly improved after treatment (P<0.05). The observation group was better among the two groups (P<0.05).After treatment, the basic biochemical indicators were improved. The observation group was better than the control group (P<0.05);Serum FGF-21 levels were significantly lower in both groups after treatment (P<0.05), and Ghrelin levels were significantly increased. There was a statistically significant difference between the two groups (P<0.05). Conclusion: The use of conventional western medicine in combination with Yiqi Yangyin Huoxue Chinese medicine for the treatment of type 2 diabetes mellitus patients with coronary heart disease can significantly improve the clinical efficacy, effectively promote the improvement of symptoms, and can be used in clinical work through serum FGF-21, Ghrelin levels combined detection of the value of Abnormal changes to predict the severity of type 2 diabetes mellitus with coronary heart disease severity and treatment effect should be widely used in clinical diagnosis and treatment. 展开更多
关键词 Type 2 diabetes mellitus COMPLICATED coronary heart disease integrated traditional chinese and western medicine FGF-21 GHRELIN
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A Survey on Treatment of Dry Eye by Traditional Chinese Medicine and Integrative Chinese and Western Medicine 被引量:2
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作者 周婉瑜 李越虹 《Chinese Journal of Integrated Traditional and Western Medicine》 2006年第2期154-159,共6页
Dry eye is now one of the most common superficial disorders in ophthalmology at home and abroad, and more and more people attach importance to the study. The ideal approach for treatment of dry eye is to normalize the... Dry eye is now one of the most common superficial disorders in ophthalmology at home and abroad, and more and more people attach importance to the study. The ideal approach for treatment of dry eye is to normalize the condition by rebuilding the superficial circumstance of the eye, and to make tear film work as well as possible so as to relieve the irritating symptoms in the eye. The authors are making a comprehensive discussion on the methods and curative effects of treating dry eye by traditional Chinese medicine and by integrative Chinese and Western medicine in recent years, so as to introduce the distinctive features of the traditional Chinese medicine and integrative Chinese and Western medicine in this field. 展开更多
关键词 dry eye traditional chinese medicine therapy integrative chinese and western medicine therapy
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Current Status of Traditional Chinese and Western Medicine Treatment of Diabetic Peripheral Vascular Disease 被引量:2
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作者 Rong Li Zongliang Song Qingxiao You 《Proceedings of Anticancer Research》 2021年第4期43-45,共3页
Diabetic peripheral vascular disease(PVD)is one of the common chronic complications of diabetes.The main clinical manifestations of PVD are numbness and coldness of the limbs,resting pain,intermittent claudication,and... Diabetic peripheral vascular disease(PVD)is one of the common chronic complications of diabetes.The main clinical manifestations of PVD are numbness and coldness of the limbs,resting pain,intermittent claudication,and other symptoms.The combined treatment involving Chinese and Western medicine for PVD has various clinical methods and definite curative effects.It is worthy of in-depth clinical research and application. 展开更多
关键词 diabetic peripheral vascular disease traditional chinese medicine treatment western medicine treatment integrated traditional chinese and western medicine treatment
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Guidelines for diagnosis and treatment of hepatic fibrosis with integrated traditional Chinese and Western medicine(2019 edition) 被引量:11
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作者 Lie-ming Xu Ping Liu 《Journal of Integrative Medicine》 SCIE CAS CSCD 2020年第3期203-213,共11页
In 2006, the Hepatology Committee of Chinese Association of Integrative Medicine issued the "Guidelines for the Prevention and Treatment of Liver Fibrosis with Integrated Traditional Chinese and Western Medicine.... In 2006, the Hepatology Committee of Chinese Association of Integrative Medicine issued the "Guidelines for the Prevention and Treatment of Liver Fibrosis with Integrated Traditional Chinese and Western Medicine." In recent years, the fields of Chinese medicine, Western medicine, and integrative medicine have made rapid advances in basic and clinical research into chronic liver disease, and accumulated new evidence for the prevention and treatment of hepatic fibrosis. Therefore, in order to meet clinical needs, liver disease experts of integrated traditional Chinese and Western medicine were united to revise the previous guidelines in order to help physicians make correct and reasonable decisions in the diagnosis and treatment of hepatic fibrosis. 展开更多
关键词 Hepatic FIBROSIS integrated traditional chinese and western medicine medicine chinese traditional Diagnosis therapy Practice GUIDELINE
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Progress of Integrative Chinese and Western Medicine in Treating Polycystic Ovarian Syndrome Caused Infertilit 被引量:4
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作者 宋娟娟 闫妙娥 +1 位作者 吴效科 侯丽辉 《Chinese Journal of Integrative Medicine》 SCIE CAS 2006年第4期312-316,共5页
Polycystic ovarian syndrome (PCOS) is one of the most popular diseases that cause menstrual dysfunction and infertility in women. The present paper is a brief retrospection on the progress in treatment of PCOS cause... Polycystic ovarian syndrome (PCOS) is one of the most popular diseases that cause menstrual dysfunction and infertility in women. The present paper is a brief retrospection on the progress in treatment of PCOS caused infertility with integrative Chinese and Western medicine (ICWM). It can be seen from these materials that using traditional Chinese medicine (TCM) recipes formulated by Shen-replenishing herbs or acupuncture to reinforce Gan-Shen, regulate Chong-Ren Channels in treating PCOS, stable clinical efficacy could be obtained, with less adverse reaction, though the effect initiated somewhat late. Whereas, when Shen-replenishing recipe and acupuncture are combined with hormone or ovulation promoting drugs of Western medicine, the above-mentioned shortcomings would be overcome. So, this combined therapy is frequently used in clinical practice. 展开更多
关键词 polycystic ovarian syndrome integrative chinese and western medicine therapy traditional chinese medicinal treatment drug therapy
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糖尿病前期中西医结合早期诊断的国内外进展与挑战
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作者 彭红叶 荆雅楠 +3 位作者 留典淳 王莹 薛雪 鲁春丽 《中国全科医学》 CAS 北大核心 2025年第3期262-272,共11页
糖尿病前期是一种表现为空腹血糖受损、糖耐量异常或两者的混合状态的疾病,属于中医“脾瘅”范畴。随着现代生活模式的改变,糖尿病前期的患病率不断升高,具有和糖尿病相当的预后风险,及时诊断并早期干预至关重要。本文从中医学和现代医... 糖尿病前期是一种表现为空腹血糖受损、糖耐量异常或两者的混合状态的疾病,属于中医“脾瘅”范畴。随着现代生活模式的改变,糖尿病前期的患病率不断升高,具有和糖尿病相当的预后风险,及时诊断并早期干预至关重要。本文从中医学和现代医学两个角度梳理了糖尿病前期的起源与定义,发现早在《素问》成书时,中医学便已对“脾瘅”形成了一定的认识。随着循证医学的发展和规范化临床研究的实施,我国逐步构建了具有中医特色的规范化糖尿病前期临床实践指南。在诊断方面,血糖检测指标类型和阈值、中医证候诊断、中西医结合诊断模型、疾病风险评分模型、生物标志物、可穿戴设备等多种无创中西医结合诊断方法不断完善,但多针对糖尿病患者的预防而非糖尿病前期的早期诊断和筛查;餐后1 h血糖可能是未来诊断糖尿病前期或糖尿病高危人群的新指标,但需进一步研究证实以推广使用。针对糖尿病前期中西医结合早期诊断面临的诊断标准的动态性、筛查流程的复杂性、临床症状的不典型性、疾病的低知晓性等挑战,未来需不断更新和完善诊断标准,融合数字化健康管理和可穿戴设备,充分发挥中医优势,构建针对糖尿病前期人群的基于中医宏观表征与组学微观数据相结合的疾病诊断模型,开发更简便、快捷的中西医结合筛查方法,实现糖尿病前期的“早筛查、早诊断、早干预、早康复”。 展开更多
关键词 糖尿病前期 脾瘅 早期诊断 中西医结合 糖尿病预防
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Effect of moxibustion combined with five‑element music therapy on postoperative pain relief after mixed hemorrhoid operation 被引量:8
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作者 Li‑Yuan WANG Hai‑Yun GAI +1 位作者 Yu WEN Ming‑Hui MA 《Journal of Integrative Nursing》 2020年第1期22-26,共5页
Objective:To investigate the effect of moxibustion combined with five‑element music therapy on the postoperative pain relief of patients undergoing surgical operation for mixed hemorrhoid with damp‑heat syndrome.Metho... Objective:To investigate the effect of moxibustion combined with five‑element music therapy on the postoperative pain relief of patients undergoing surgical operation for mixed hemorrhoid with damp‑heat syndrome.Methods:Totally,159 patients meeting the inclusion criteria were assigned to the control group,study group 1,and study group 2,with 53 cases in each group.All patients received routine care after surgical treatment,including acupoint application and Chinese herbal fumigation.In addition,patients in the study group 1 received moxibustion,and those in the study group 2 were given moxibustion combined with five‑element music therapy.The degree of postoperative pain was evaluated using visual analog scale(VAS).Results:There was no significant difference in VAS score on pain during dressing changes among three groups(P>0.05).After 3,5,and 7 days of intervention,there was a significant difference in VAS score on pain at rest among three groups(P<0.001),and VAS score in the study group 2 was lower than that in the study group 1 and the control group after 3 and 5 days of intervention,respectively(P<0.05).Conclusion:Moxibustion combined with five‑element music therapy is effective to relieve the postoperative pain of patients undergoing a surgical operation for mixed hemorrhoids with damp‑heat syndrome. 展开更多
关键词 Five‑element music therapy five‑tone therapy mixed hemorrhoid MOXIBUSTION nursing of integrated traditional chinese and western medicine pain
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Nursing Based on Syndrome Differentiation Combined with Auricular Plaster Therapy in Alleviating Insomnia 被引量:4
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作者 Ning WANG Shu-Li MA +1 位作者 Xi LI Li-Xia YANG 《Journal of Integrative Nursing》 2019年第1期27-34,共8页
Objective:To observe the effect of auricular point pressing combined with nursing based on syndrome differentiation in the treatment of insomnia patients.Methods:Totally 92 patients with insomnia were randomly divided... Objective:To observe the effect of auricular point pressing combined with nursing based on syndrome differentiation in the treatment of insomnia patients.Methods:Totally 92 patients with insomnia were randomly divided into the observation groupgiven auricular point pressing combined with nursing care based on syndrome differentiation and the control group treated with auricular point pressing alone.The improvement of Pittsburgh Sleep Quality Index(PSQI),TCM Syndrome Score and nursing satisfaction were compared between the 2 groups.Results:The time effect of PSQI total score and 6 factors in both groups were statistically significant(P<0.05).The time effect,interaction effect and inter-group effect of subjective sleep quality,PSQI total score were statistically significant(P<0.05);the 4 inter-group factors of sleep quality,sleep latency,sleep duration and daytime function were statistically significant(P<0.05).The total score of TCM syndromes in the observation group was lower than that in the control group(P<0.05),and the satisfaction rate in the observation group higher than that in the control group(80.43%vs.60.86%,P<0.05).Conclusion:Auricular point pressing combined withnursing based on syndrome differentiation can effectively improve the sleep quality of insomnia patients,and has significant advantages in improving TCM syndromes,as well as gained higher nursing satisfaction from patients. 展开更多
关键词 INSOMNIA Auricular-plaster therapy/Auricular point pressing Nursing based on syndrome differentiation/Syndrome differentiation and nursing Sleep quality Nursing of integrated traditional chinese and western medicine
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异位妊娠中西医结合保守治疗的现状和展望 被引量:1
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作者 纪诚 陈雪 +1 位作者 叶聪 杨依玲 《长春中医药大学学报》 2024年第3期340-344,共5页
异位妊娠作为一种常见的妇科急症,其治疗策略的优化对于提升育龄女性生殖健康具有重要意义。该文综合分析了中西医结合在异位妊娠保守治疗中的应用现状,并探讨了其未来发展趋势。通过对甲氨蝶呤单药治疗和腹腔镜手术等西医传统方法的评... 异位妊娠作为一种常见的妇科急症,其治疗策略的优化对于提升育龄女性生殖健康具有重要意义。该文综合分析了中西医结合在异位妊娠保守治疗中的应用现状,并探讨了其未来发展趋势。通过对甲氨蝶呤单药治疗和腹腔镜手术等西医传统方法的评估,与中医药治疗如中药、针灸和推拿等方法的综合疗效进行对比,揭示了中西医结合治疗在提高治疗效果和降低副作用方面的潜力。展望未来,个体化治疗方案、微创技术的进步和中药新药的开发,预计将为异位妊娠的保守治疗提供更广阔的视野。本综述强调了中西医结合治疗异位妊娠的优势,并为其在临床实践中的深入应用提供了科学依据。 展开更多
关键词 异位妊娠 中西医结合 保守治疗 药物治疗 针灸疗法 手术治疗
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半夏泻心汤加减联合艾司奥美拉唑镁肠溶片治疗非糜烂性胃食管反流病肝胃郁热证疗效及安全性 被引量:1
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作者 陈丽 张江春 +1 位作者 郭洁 万媛 《河北中医》 2024年第9期1455-1459,共5页
目的观察半夏泻心汤加减联合艾司奥美拉唑镁肠溶片治疗非糜烂性胃食管反流病(NERD)肝胃郁热证的疗效及安全性。方法选择NERD肝胃郁热证患者98例,按随机数字表法分为2组,对照组(n=49)予艾司奥美拉唑镁肠溶片,治疗组(n=49)在对照组基础上... 目的观察半夏泻心汤加减联合艾司奥美拉唑镁肠溶片治疗非糜烂性胃食管反流病(NERD)肝胃郁热证的疗效及安全性。方法选择NERD肝胃郁热证患者98例,按随机数字表法分为2组,对照组(n=49)予艾司奥美拉唑镁肠溶片,治疗组(n=49)在对照组基础上辅以半夏泻心汤加减,连续治疗8周。比较2组疗效及治疗前后中医证候总积分、食管动力[下食管括约肌静息压(LESP)、上食管括约肌静息压(UESP)]、胃肠激素[胃动素、胃泌素、胃促生长素(Ghrelin)、血管活性肠肽(VIP)]、汉密尔顿抑郁量表-17(HAMD-17)评分变化,并观察2组治疗期间不良反应发生情况。结果治疗组总有效率为95.92%(47/49),对照组为73.47%(36/49),治疗组临床疗效优于对照组(P<0.05)。2组治疗后中医证候总积分、HAMD-17评分均较本组治疗前降低(P<0.05),且治疗组均低于对照组(P<0.05)。2组治疗后LESP均较本组治疗前升高(P<0.05),UESP均较本组治疗前降低(P<0.05);治疗后治疗组LESP高于对照组(P<0.05),UESP低于对照组(P<0.05)。2组治疗后胃动素、胃泌素、Ghrelin均较本组治疗前升高(P<0.05),VIP均较本组治疗前降低(P<0.05);治疗后治疗组胃动素、胃泌素、Ghrelin高于对照组(P<0.05),VIP低于对照组(P<0.05)。2组治疗期间均未发生不良反应。结论半夏泻心汤加减联合艾司奥美拉唑镁肠溶片治疗NERD肝胃郁热证疗效肯定,能改善食管动力及抑郁状态,调节胃肠激素,且安全性高。 展开更多
关键词 胃食管反流 中西医结合疗法
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身痛逐瘀汤加味联合盐酸普拉克索片治疗痰瘀痹阻型不宁腿综合征的临床观察 被引量:1
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作者 杜青 宁倩 +5 位作者 徐栋 李鑫 顾宝东 王英超 马先军 赵晓慧 《河北中医》 2024年第1期25-28,共4页
目的观察身痛逐瘀汤加味联合盐酸普拉克索片治疗痰瘀痹阻型不宁腿综合征(RLS)患者的临床疗效。方法将50名痰瘀痹阻型RLS患者按照随机数字表法分为2组,对照组25例予盐酸普拉克索片治疗,治疗组25例在对照组基础上联合身痛逐瘀汤加味治疗。... 目的观察身痛逐瘀汤加味联合盐酸普拉克索片治疗痰瘀痹阻型不宁腿综合征(RLS)患者的临床疗效。方法将50名痰瘀痹阻型RLS患者按照随机数字表法分为2组,对照组25例予盐酸普拉克索片治疗,治疗组25例在对照组基础上联合身痛逐瘀汤加味治疗。2组均治疗1周为1个疗程,治疗2个疗程后统计疗效,比较2组治疗前后国际RLS严重程度评分量表(IRLS)评分、匹兹堡睡眠质量指数量表(PSQI)评分及中医症状评分变化情况。结果治疗组总有效率92.00%(23/25),对照组总有效率60.00%(15/25),治疗组总有效率高于对照组(P<0.05)。与本组治疗前比较,2组治疗后IRLS评分、PSQI评分及中医症状评分均降低(P<0.05),且治疗组治疗后IRLS评分、PSQI评分及中医症状评分均低于对照组(P<0.05)。结论身痛逐瘀汤加味联合盐酸普拉克索片治疗痰瘀痹阻型RLS疗效确切,可有效改善患者临床症状及中医症状,改善患者睡眠质量,操作简便,临床疗效显著,安全性良好。 展开更多
关键词 不宁腿综合征 普拉克索 身痛逐瘀汤 痰瘀痹阻 中西医结合疗法
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扶正通淋散治疗脾肾两虚湿热内蕴型复发性尿路感染的临床研究 被引量:1
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作者 刘兴国 聂晨 +3 位作者 付明洁 曹繁华 杜冬琛 冯定华 《河北中医》 2024年第1期51-55,共5页
目的观察扶正通淋散治疗脾肾两虚湿热内蕴型复发性尿路感染的临床疗效。方法将108例复发性尿路感染患者按照随机数字表方法分为3组,中药组36例予扶正通淋散治疗,西药组36例予临床常规西医治疗,联合组36例予扶正通淋散联合临床常规西医... 目的观察扶正通淋散治疗脾肾两虚湿热内蕴型复发性尿路感染的临床疗效。方法将108例复发性尿路感染患者按照随机数字表方法分为3组,中药组36例予扶正通淋散治疗,西药组36例予临床常规西医治疗,联合组36例予扶正通淋散联合临床常规西医治疗。3组均治疗3个月,随访6个月。比较3组治疗前后尿常规[白细胞计数(WBC)、红细胞计数(RBC)]、尿细菌培养结果、血清炎症相关指标[肿瘤坏死因子α(TNF-α)、降钙素原(PCT)、白细胞介素6(IL-6)],治疗前及治疗结束后1个月健康调查简表(SF-36)评分,并统计临床疗效及复发率。结果联合组总有效率91.67%(33/36),中药组总有效率72.22%(26/36),西药组总有效率66.67%(24/36),联合组疗效优于中药组、西药组(P<0.05)。3组治疗后尿常规WBC、RBC均较本组治疗前降低(P<0.05),且联合组治疗后均低于中药组、西药组(P<0.05),中药组均低于西药组(P<0.05)。3组治疗后血清TNF-α、PCT、IL-6水平均较本组治疗前降低(P<0.05),且联合组治疗后均低于中药组、西药组(P<0.05),中药组均低于西药组(P<0.05)。3组治疗后SF-36量表各维度评分均较本组治疗前升高(P<0.05),且联合组均高于中药组、西药组(P<0.05)。联合组尿路感染复发率显著低于中药组、西药组(P<0.05)。结论扶正通淋散治疗脾肾两虚湿热内蕴型复发性尿路感染有较好疗效,可以显著改善患者炎症水平和生活质量,降低复发率。 展开更多
关键词 复发性尿路感染 中西医结合疗法
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耳穴疗法联合普瑞巴林胶囊治疗气滞血瘀型带状疱疹后遗神经痛临床观察 被引量:2
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作者 于涓 《中国中医药现代远程教育》 2024年第12期136-138,共3页
目的分析耳穴疗法联合普瑞巴林胶囊治疗气滞血瘀型带状疱疹后遗神经痛(PHN)的临床效果。方法经随机方式把80例带状疱疹(HZ)住院患者归入对照组、治疗组,分别实施常规治护+普瑞巴林胶囊口服止痛疗法、常规治护+中医耳穴压豆+普瑞巴林胶... 目的分析耳穴疗法联合普瑞巴林胶囊治疗气滞血瘀型带状疱疹后遗神经痛(PHN)的临床效果。方法经随机方式把80例带状疱疹(HZ)住院患者归入对照组、治疗组,分别实施常规治护+普瑞巴林胶囊口服止痛疗法、常规治护+中医耳穴压豆+普瑞巴林胶囊口服止痛疗法,对比两组神经痛改善状况。结果在疼痛缓解方面,相较对照组,治疗组具有显著优势(P<0.05)。治疗组总有效率为90.00%(36/40),高于对照组的77.50%(31/40);治疗组的复发率为10.00%(4/40),低于对照组的22.50%(9/40)(P<0.05)。结论耳穴压豆+普瑞巴林胶囊疗法对于气滞血瘀型PHN的缓解有着积极作用,同时止痛效果相较单用普瑞巴林胶囊更具优势。 展开更多
关键词 蛇串疮 带状疱疹后遗神经痛 气滞血瘀证 耳穴压豆疗法 普瑞巴林 中西医结合疗法
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清热利湿方联合美沙拉嗪治疗湿热内蕴证糖尿病肠病临床疗效观察
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作者 李明哲 柳越冬 +2 位作者 陈萌 张威 石岩 《中华中医药学刊》 CAS 北大核心 2024年第8期50-53,共4页
目的探讨清热利湿方治疗糖尿病肠病疗效及对患者生活质量的影响。方法将48例湿热内蕴证糖尿病肠病患者按随机数字表法分观察组和对照组,每组24例;两组均口服美沙拉嗪肠溶片,观察组加予清热利湿方日2次口服治疗,统计肠炎疾病量表(inflamm... 目的探讨清热利湿方治疗糖尿病肠病疗效及对患者生活质量的影响。方法将48例湿热内蕴证糖尿病肠病患者按随机数字表法分观察组和对照组,每组24例;两组均口服美沙拉嗪肠溶片,观察组加予清热利湿方日2次口服治疗,统计肠炎疾病量表(inflammatory bowel disease questionnaire,IBDQ)评分及相关症状体征。结果观察组与对照组IBDQ评分各分项得分治疗后均高于治疗前,但观察组分数增加较为明显,且观察组在全身症状、肠道症状、情感功能、社会功能、总分等方面得分增加均高于对照组,在全身症状改善方面尤为显著。两组在生活质量量表(the MOS item short from health survey,SF-36)量表中生理机能(physical functioning,PF)、生理职能(role physical,RP)、活力(vitality,VT)、精神健康(mental health,MH)、整体健康(general health,GH)等方面治疗前与治疗后差异有统计学意义(均P<0.05)。观察组总有效率91.67%(22/24),两组间疗效比较差异有统计学意义(P<0.05)。两组病例均耐受良好,未见明显不良反应,1年内复发率观察组低于对照组(均P<0.05)。结论清热利湿方可以有效清热利湿,改善患者病情,是针对糖尿病肠病的一种有效治疗方案,可以提高湿热内蕴证糖尿病肠病患者的治疗有效率,明显提高患者的生活质量,值得临床进一步研究及推广。 展开更多
关键词 糖尿病肠病 清热利湿方 湿热内蕴 生活质量 中西医结合
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清咳平喘颗粒对COPD急性加重期的临床疗效
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作者 李冬生 秦艺榕 +3 位作者 乔曼 迟航 崔青敏 李晓秋 《天津医药》 CAS 2024年第8期854-857,共4页
目的探讨清咳平喘颗粒对慢性阻塞性肺疾病急性加重期(AECOPD)患者临床疗效的影响。方法选取80例呼吸科住院治疗的AECOPD患者,其中常规组和联合组各40例,分别于治疗前、治疗第2周末、治疗1个月后观察2组患者自我评估测试(CAT)评分、疗效... 目的探讨清咳平喘颗粒对慢性阻塞性肺疾病急性加重期(AECOPD)患者临床疗效的影响。方法选取80例呼吸科住院治疗的AECOPD患者,其中常规组和联合组各40例,分别于治疗前、治疗第2周末、治疗1个月后观察2组患者自我评估测试(CAT)评分、疗效指数、白细胞介素(IL)-6水平、C-反应蛋白(CRP)水平、第1秒用力呼气容积(FEV1)/用力肺活量(FVC)、FEV1占预计值百分比(FEV1%pred)的差异。结果联合组总有效率高于常规组(92.5%vs.75.0%,P<0.05)。治疗第2周末,2组FEV1%pred、FEV1/FVC、IL-6水平、CRP水平与治疗前比较均有所改善,且联合组改善程度优于常规组(P<0.05),2组患者呼吸衰竭比例均较治疗前明显好转;随访1个月,联合组CAT评分回弹率低于常规组(P<0.05);2组不良反应发生率差异无统计学意义(12.5%vs.2.5%,P>0.05)。结论清咳平喘颗粒能有效改善AECOPD患者的临床症状及肺功能,提高生活质量。 展开更多
关键词 肺疾病 慢性阻塞性 痰浊阻肺 中西医结合疗法 清咳平喘颗粒
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复方丹参滴丸联合雷米普利片对糖尿病肾病患者肾功能、P选择素水平及糖脂代谢的影响
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作者 黄秀丽 吴艳 +2 位作者 付彩雯 喻荷淋 周艳君 《河北中医》 2024年第5期713-716,721,共5页
目的观察复方丹参滴丸联合雷米普利片对糖尿病肾病(DN)患者肾功能、P选择素水平及糖脂代谢的影响。方法将88例DN患者按照随机数字表法分为2组,对照组44例予雷米普利片治疗,治疗组44例在对照组治疗基础上予复方丹参滴丸治疗。2组均治疗4... 目的观察复方丹参滴丸联合雷米普利片对糖尿病肾病(DN)患者肾功能、P选择素水平及糖脂代谢的影响。方法将88例DN患者按照随机数字表法分为2组,对照组44例予雷米普利片治疗,治疗组44例在对照组治疗基础上予复方丹参滴丸治疗。2组均治疗4周。比较2组治疗前后中医证候评分、肾功能[血尿素氮(BUN)、血肌酐(SCr)及尿蛋白排泄率]、糖脂代谢[餐后2 h血糖(2 hPG)、空腹血糖(FPG)、甘油三酯(TG)、总胆固醇(TC)]、炎症因子[超敏C反应蛋白(hs-CRP)、P选择素、肿瘤坏死因子α(TNF-α)]水平及不良反应发生率。结果2组治疗后中医证候各项评分均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。2组治疗后BUN、SCr、尿蛋白排泄率均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。2组治疗后FPG、2 hPG、TG、TC水平均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。2组治疗后血清hs-CRP、P选择素、TNF-α水平均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。治疗组不良反应发生率11.36%(5/44),对照组不良反应发生率4.55%(2/44),2组比较差异无统计学意义(P>0.05)。结论复方丹参滴丸联合雷米普利片治疗DN可有效提高肾功能,改善糖脂代谢,减轻炎症反应,降低P选择素水平,安全有效。 展开更多
关键词 糖尿病肾病 中西医结合疗法
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二天养胎汤联合低分子量肝素治疗复发性自然流产血栓前状态的临床研究
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作者 向丽娟 戴海青 +2 位作者 戴小萍 曾根 周意 《河北中医》 2024年第10期1617-1622,共6页
目的观察二天养胎汤联合低分子量肝素对复发性自然流产(RSA)血栓前状态的治疗效果。方法选取2021年10月至2022年11月海南省中医院妇产科门诊就诊及住院的RSA血栓前状态早期妊娠,中医辨证为肾虚血瘀患者80例,采用随机数字法将符合纳入标... 目的观察二天养胎汤联合低分子量肝素对复发性自然流产(RSA)血栓前状态的治疗效果。方法选取2021年10月至2022年11月海南省中医院妇产科门诊就诊及住院的RSA血栓前状态早期妊娠,中医辨证为肾虚血瘀患者80例,采用随机数字法将符合纳入标准患者分为2组,二天养胎汤联合低分子量肝素治疗组(联合治疗组)和低分子量肝素治疗组(肝素治疗组)。其中肝素治疗组入院后给予患者脐周皮下注射低分子量肝素4100 U,每日1次,用药至孕12周。联合治疗组同期予中药二天养胎汤口服。观察各组患者用药前后的治疗效果、中医证候评分改善情况、凝血指标及生长因子和Rho相关卷曲螺旋形成蛋白激酶/LIM激酶1/丝切蛋白(ROCK/LIMK1/Cofilin)通路相关基因表达情况。结果联合治疗组与肝素治疗组相比,其总有效率及活产率均较高,差异有统计学意义(P<0.05)。2组患者治疗前,中医证候积分无明显差别(P>0.05);2组患者治疗后与治疗前相比中医证候积分均有改善(P<0.05),但联合治疗组与肝素治疗组相比,其中医证候评分较低,差异有统计学意义(P<0.05)。2组患者治疗前,各凝血指标无明显差别(P>0.05);联合治疗组治疗后与治疗前相比各凝血指标均有改善(P<0.05);肝素治疗组治疗后与治疗前相比,其纤维蛋白原(FIB)、D-二聚体(D-D)、抗凝血酶Ⅲ(ATⅢ)、活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)有改善(P<0.05)。联合治疗组与肝素治疗组相比,其凝血功能指标均有不同程度的改善,差异有统计学意义(P<0.05)。2组患者治疗前,孕激素及血清相关因子无明显差别(P>0.05);联合治疗组治疗后与治疗前相比各凝血指标均有改善(P<0.05);肝素治疗组治疗后与治疗前相比,其孕酮(P)、人绒毛膜促性腺激素(β-HCG)、一氧化氮(NO)、透明质酸(HA)、血管内皮生长因子A(VEGFA)、胰岛素样生长因子-1(IGF-1)、转化生长因子β1(TGF-β1)有改善(P<0.05)。联合治疗组与肝素治疗组相比,孕激素及血清相关因子均有不同程度的改善,差异有统计学意义(P<0.05)。联合治疗组与肝素治疗组相比,其ROCK、LIMK1表达有所升高(P<0.05),其中LIMK1升高最明显。结论二天养胎汤能够有效改善RSA血栓前状态患者的活产率,维持凝血功能的正常;除此作用外,还可以通过改善血清生长因子VEGFA、IGF-1、TGF-β1以及血管功能保护因子NO、HA调节血栓前状态RSA患者的血管生长及维持血管正常功能,而这些作用可能与二天养胎汤能够通过促进Cofilin的磷酸化激酶ROCK、LIMK1的表达相关。 展开更多
关键词 复发性流产 低分子量肝素 中西医结合疗法
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1例肾阳虚型高血压患者的“双心护理”体会
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作者 崔淑节 胡瑶瑶 +2 位作者 章玲群 徐蒙 任鹏娜 《中西医结合护理》 2024年第2期83-86,共4页
本文总结了1例肾阳虚型高血压患者的“双心护理”体会。护理要点包括病情观察、血压监测、用药护理、中医特色护理等,并在此基础上给予心理评估、“双心”教育等干预措施。基于“双心护理”模式开展中西医结合护理,有助于改善患者症状,... 本文总结了1例肾阳虚型高血压患者的“双心护理”体会。护理要点包括病情观察、血压监测、用药护理、中医特色护理等,并在此基础上给予心理评估、“双心”教育等干预措施。基于“双心护理”模式开展中西医结合护理,有助于改善患者症状,缓解心理压力,提高治疗依从性,促进患者康复。 展开更多
关键词 高血压 中西医结合护理 刮痧 艾灸 认知行为干预 双心护理
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参芪补肺汤联合孟鲁司特钠片治疗非小细胞肺癌术后慢性咳嗽的临床研究
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作者 李晓娣 谢佳佳 +3 位作者 王明选 杨双 易超 文琪 《河北中医》 2024年第8期1292-1296,共5页
目的观察参芪补肺汤联合孟鲁司特钠片治疗非小细胞肺癌(NSCLC)术后慢性咳嗽的临床疗效。方法将100例NSCLC术后慢性咳嗽患者按照随机数字表法分为2组,对照组50例予孟鲁司特钠片治疗,治疗组50例在对照组治疗基础上联合参芪补肺汤治疗。2... 目的观察参芪补肺汤联合孟鲁司特钠片治疗非小细胞肺癌(NSCLC)术后慢性咳嗽的临床疗效。方法将100例NSCLC术后慢性咳嗽患者按照随机数字表法分为2组,对照组50例予孟鲁司特钠片治疗,治疗组50例在对照组治疗基础上联合参芪补肺汤治疗。2组均治疗4周。比较2组治疗前后咳嗽症状、莱彻斯特咳嗽生命质量问卷(LCQ-MC)评分、肺功能指标[用力肺活量(FVC)、第1 s用力呼气容积(FEV_(1))、FEV_(1)/FVC、呼气峰流量(PEF)]、炎症指标[白细胞介素8(IL-8)、肿瘤坏死因子α(TNF-α)、降钙素原(PCT)、白细胞介素6(IL-6)]、中医证候评分,并统计2组不良反应发生率、复发率和疗效。结果治疗组总有效率98.00%(49/50),对照组总有效率82.00%(41/50),治疗组临床疗效优于对照组(P<0.05)。2组治疗后日间与夜间咳嗽症状评分均较本组治疗降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05),2组治疗后LCQ-MC评分均升高(P<0.05),且治疗组治疗后高于对照组(P<0.05)。2组治疗后FVC、FEV_(1)、FEV_(1)/FVC、PEF均较本组治疗前升高(P<0.05),且治疗组治疗后均高于对照组(P<0.05)。2组治疗后IL-8、TNF-α、PCT、IL-6均较本组治疗降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。2组治疗后中医证候各项评分均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。治疗组不良反应发生率4.00%(2/50),对照组不良反应发生率18.00%(9/50),治疗组不良反应发生率低于对照组(P<0.05)。治疗组复发率4.08%(2/49),对照组24.39%(10/41),治疗组复发率低于对照组(P<0.05)。结论参芪补肺汤联合孟鲁司特钠片治疗NSCLC术后慢性咳嗽患者疗效显著,能够有效缓解咳嗽症状,改善患者肺功能,提升LCQ-MC评分,且不良反应发生率与复发率降低,具有临床应用价值。 展开更多
关键词 肺癌 非小细胞型 术后 慢性咳嗽 中西医结合疗法
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柴胡加龙骨牡蛎汤联合艾司西酞普兰对卒中后抑郁患者神经功能、抑郁状态和血清脑源性神经营养因子、5-羟色胺水平的影响
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作者 凌志香 张兰坤 刘元月 《河北中医》 2024年第9期1472-1474,1479,共4页
目的观察柴胡加龙骨牡蛎汤联合艾司西酞普兰对卒中后抑郁(PSD)患者神经功能、抑郁状态及血清脑源性神经营养因子(BDNF)、5-羟色胺(5-HT)水平的影响。方法将98例PSD患者按照随机数字表法分为治疗组和对照组,各49例。对照组予草酸艾司西... 目的观察柴胡加龙骨牡蛎汤联合艾司西酞普兰对卒中后抑郁(PSD)患者神经功能、抑郁状态及血清脑源性神经营养因子(BDNF)、5-羟色胺(5-HT)水平的影响。方法将98例PSD患者按照随机数字表法分为治疗组和对照组,各49例。对照组予草酸艾司西酞普兰片治疗6周,治疗组在对照组治疗基础上加柴胡加龙骨牡蛎汤治疗6周。比较2组疗效及治疗前、治疗3周和治疗6周美国国立卫生研究院卒中量表(NIHSS)评分和血清5-HT、BDNF水平。结果治疗组总有效率87.76%(43/49),对照组总有效率69.39%(34/49),治疗组总有效率高于对照组(P<0.05)。2组治疗3、6周NIHSS、HAMD评分均显著低于本组治疗前(P<0.05),治疗6周NIHSS和HAMD评分均显著低于本组治疗3周(P<0.05);治疗3、6周治疗组NIHSS和HAMD评分均显著低于对照组同期(P<0.05)。2组治疗3、6周5-HT、BDN水平均显著高于本组治疗前(P<0.05),治疗6周5-HT、BDNF水平均显著高于本组治疗3周(P<0.05);治疗3、6周治疗组5-HT和BDNF水平显著高于对照组同期(P<0.05)。结论柴胡加龙骨牡蛎汤联合艾司西酞普兰能改善PSD抑郁状态、神经功能及血清BDNF、5-HT水平。 展开更多
关键词 卒中 抑郁 中西医结合疗法
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