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Research progress on biodosimeters of ionizing radiation damage 被引量:1
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作者 Changyan Xiao Ningning He +2 位作者 Yang Liu Yan Wang Qiang Liu 《Radiation Medicine and Protection》 2020年第3期127-132,共6页
Ionizing radiation can cause radiation injury to the human body under certain circumstances,such as unexpected radiation accidents and nuclear terrorist attacks.Methods that can accurately and rapidly measure the biol... Ionizing radiation can cause radiation injury to the human body under certain circumstances,such as unexpected radiation accidents and nuclear terrorist attacks.Methods that can accurately and rapidly measure the biological effects are necessary for rational triage and treatment of affected patients.In recent decades,significant researches attention has been focused on the development of accurate and efficient biodosimeters.In this review,we summarize recent developments in biological dosimeters,with a primary focus on cell-based and molecular markers,including comet assay,dicentric chromosome aberration,γ-H2AX,micronuclei,microRNA,lncRNA,and 8-Oxo-dG. 展开更多
关键词 Ionizing radiation Radiation injury Biodosimeter Comet assay dicentric chromosome aberration Γ-H2AX Micronuclei MICRORNA lncRNA 8-Oxo-dG
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