A one-pot reaction sequence of sequential phosphine-promoted tandem annulations of aryl trifluoromethyl ketones and MBH（Morita-Baylis-Hillman） carbonates and DBU-mediated aminolysis was developed. This method provid...A one-pot reaction sequence of sequential phosphine-promoted tandem annulations of aryl trifluoromethyl ketones and MBH（Morita-Baylis-Hillman） carbonates and DBU-mediated aminolysis was developed. This method provides a step-economical approach to trifluoromethylated dienamides with diverse structural complexity from readily available starting materials in moderate yields.展开更多
基金supported by the National Natural Science Foundation of China (No. 21302034)the Fundamental Research Funds for the Central Universities (No. 2013HGQC0028)
文摘A one-pot reaction sequence of sequential phosphine-promoted tandem annulations of aryl trifluoromethyl ketones and MBH（Morita-Baylis-Hillman） carbonates and DBU-mediated aminolysis was developed. This method provides a step-economical approach to trifluoromethylated dienamides with diverse structural complexity from readily available starting materials in moderate yields.
