The difference-ratio relations are introduced to separate tidal constituents that are aliaseddue to the sampling interval and sampling span of the TOPEX/POSEIDON altimeter. It is found that some tidal constituents suc...The difference-ratio relations are introduced to separate tidal constituents that are aliaseddue to the sampling interval and sampling span of the TOPEX/POSEIDON altimeter. It is found that some tidal constituents such as K_1 and SSA, though aliased at along track points, are not aliased at crossover points beeause the data at crossover points are double those at along track points. So the harmonic analysis method can be employed directly for the analysis of time series at crossover points. Then the difference-ratio relations from crossover points are introduced to analyze the time series at along track points. The TOPEX/POSEIDON data in the Northwest Pacific are analyzed with this method. The results from this method agree well with tidal constants from tidal gauges.展开更多
In this paper,a compact difference scheme is established for the heat equations with multi-point boundary value conditions.The truncation error of the difference scheme is O(τ2+h^4),where t and h are the temporal ste...In this paper,a compact difference scheme is established for the heat equations with multi-point boundary value conditions.The truncation error of the difference scheme is O(τ2+h^4),where t and h are the temporal step size and the spatial step size.A prior estimate of the difference solution in a weighted norm is obtained.The unique solvability,stability and convergence of the difference scheme are proved by the energy method.The theoretical statements for the solution of the difference scheme are supported by numerical examples.展开更多
The main harmonic components in nonlinear differential equations can be solved by using the harmonic balance principle. The nonlinear coupling relation among various harmonics can be found by balance theorem of freque...The main harmonic components in nonlinear differential equations can be solved by using the harmonic balance principle. The nonlinear coupling relation among various harmonics can be found by balance theorem of frequency domain. The superhet receiver circuits which are described by nonlinear differential equation of comprising even degree terms include three main harmonic components: the difference frequency and two signal frequencies. Based on the nonlinear coupling relation, taking superhet circuit as an example, this paper demonstrates that the every one of three main harmonics in networks must individually observe conservation of complex power. The power of difference frequency is from variable-frequency device. And total dissipative power of each harmonic is equal to zero. These conclusions can also be verified by the traditional harmonic analysis. The oscillation solutions which consist of the mixture of three main harmonics possess very long oscillation period, the spectral distribution are very tight, similar to evolution from doubling period leading to chaos. It can be illustrated that the chaos is sufficient or infinite extension of the oscillation period. In fact, the oscillation solutions plotted by numerical simulation all are certainly a periodic function of discrete spectrum. When phase portrait plotted hasn’t finished one cycle, it is shown as aperiodic chaos.展开更多
Kizmaz [13] studied the difference sequence spaces ∞(A), c(A), and co(A). Several article dealt with the sets of sequences of m-th order difference of which are bounded, convergent, or convergent to zero. Alta...Kizmaz [13] studied the difference sequence spaces ∞(A), c(A), and co(A). Several article dealt with the sets of sequences of m-th order difference of which are bounded, convergent, or convergent to zero. Altay and Basar [5] and Altay, Basar, and Mursaleen [7] introduced the Euler sequence spaces e0^r, ec^r, and e∞^r, respectively. The main purpose of this article is to introduce the spaces e0^r△^(m)), ec^r△^(m)), and e∞^r△^(m))consisting of all sequences whose mth order differences are in the Euler spaces e0^r, ec^r, and e∞^r, respectively. Moreover, the authors give some topological properties and inclusion relations, and determine the α-, β-, and γ-duals of the spaces e0^r△^(m)), ec^r△^(m)), and e∞^r△^(m)), and the Schauder basis of the spaces e0^r△^(m)), ec^r△^(m)). The last section of the article is devoted to the characterization of some matrix mappings on the sequence space ec^r△^(m)).展开更多
In this article, using generalized weighted mean and difference matrix of order m, we introduce the paranormed sequence space l(u, v, p; △(m)), which consist of the sequences whose generalized weighted △(m)-di...In this article, using generalized weighted mean and difference matrix of order m, we introduce the paranormed sequence space l(u, v, p; △(m)), which consist of the sequences whose generalized weighted △(m)-difference means are in the linear space l(p) defined by I.J.Maddox. Also, we determine the basis of this space and compute its α-, β- and γ-duals. Further, we give the characterization of the classes of matrix mappings from l(u, v, p, △(m)) to l∞, c, and co. Finally, we apply the Hausdorff measure of noncompacness to characterize some classes of compact operators given by matrices on the space lp(U, v, △(m)) (1 ≤ p 〈 ∞).展开更多
It is theoretically investigated the generation of higher harmonics of two-dimensional and three-dimensional terahertz electromagnetic beams in nonlinear crystals. The attention is paid to crystalline paraelectrics li...It is theoretically investigated the generation of higher harmonics of two-dimensional and three-dimensional terahertz electromagnetic beams in nonlinear crystals. The attention is paid to crystalline paraelectrics like SrTiO<sub>3</sub> under the temperatures 60 - 200 K, these crystals possess the cubic nonlinearity. The bias electric field is applied to provide the dominating quadratic nonlinearity. The initial focusing of the beams not only increases the efficiency of generation of higher harmonics, but alto makes possible to select maxima of different higher harmonics at some distances from the input. At lower temperatures the nonlinearity behaves at smaller input amplitudes, whereas at higher temperatures the harmonic generation can be observed at higher frequencies up to 1.5 THz. In three-dimensional beams the peak amplitudes of higher harmonics can be bigger than in two-dimensional beams, but the ratios of these peak values to the maximum values of the focused first harmonic are smaller than in two-dimensional beams.展开更多
The quantization of the forced harmonic oscillator is studied with the quantum variable (<em>x</em>, <span style="white-space:nowrap;"><em><sub>v</sub><sup style="...The quantization of the forced harmonic oscillator is studied with the quantum variable (<em>x</em>, <span style="white-space:nowrap;"><em><sub>v</sub><sup style="margin-left:-8px;">∧</sup></em></span>), with the commutation relation <img src="Edit_28f5b839-7de4-41e5-9ed8-69dc1bf72c2c.bmp" alt="" />, and using a Schr<span style="white-space:nowrap;"><span style="white-space:nowrap;"><span style="white-space:nowrap;">ö</span></span></span>dinger’s like equation on these variable, and associating a linear operator to a constant of motion <em>K</em> (<em>x, v, t</em>) of the classical system, The comparison with the quantization in the space (<em>x, p</em>) is done with the usual Schr<span style="white-space:nowrap;"><span style="white-space:nowrap;"><span style="white-space:nowrap;">ö</span></span></span>dinger’s equation for the Hamiltonian <em>H</em><span style="white-space:normal;">(</span><em style="white-space:normal;">x, p, t</em><span style="white-space:normal;">)</span>, and with the commutation relation <img src="Edit_cca7e318-5b35-4c55-8f09-6089970ce9a2.bmp" alt="" />. It is found that for the non-resonant case, both forms of quantization bring about the same result. However, for the resonant case, both forms of quantization are different, and the probability for the system to be in the exited state for the (<em style="white-space:normal;">x</em><span style="white-space:normal;">, </span><em><sub>v</sub><sup style="margin-left:-8px;">∧</sup></em>) quantization has fewer oscillations than the (<em style="white-space:normal;">x</em><span style="white-space:normal;">, </span><em style="white-space:normal;"><sub>p</sub><sup style="margin-left:-8px;">∧</sup></em>) quantization, the average energy of the system is higher in (<em style="white-space:normal;">x</em><span style="white-space:normal;">, </span><em style="white-space:normal;"><sub>p</sub><sup style="margin-left:-8px;">∧</sup></em>) quantization than on the (<em style="white-space:normal;">x</em><span style="white-space:normal;">, </span><em style="white-space:normal;"><sub>v</sub><sup style="margin-left:-8px;">∧</sup></em>) quantization, and the Boltzmann-Shannon entropy on the (<em style="white-space:normal;">x</em><span style="white-space:normal;">, </span><em style="white-space:normal;"><sub>p</sub><sup style="margin-left:-8px;">∧</sup></em>) quantization is higher than on the (<em style="white-space:normal;">x</em><span style="white-space:normal;">, </span><em style="white-space:normal;"><sub>v</sub><sup style="margin-left:-8px;">∧</sup></em>) quantization.展开更多
A semi-implicit and Eulerian - Lagrangian finite difference method for three-dimensionalshallow flow has been extended to a more complete system of equations incorporating second-moment turbulence closure model and tr...A semi-implicit and Eulerian - Lagrangian finite difference method for three-dimensionalshallow flow has been extended to a more complete system of equations incorporating second-moment turbulence closure model and transport equations of salinity and temperature. The simulation for flooding and drying of mudflats has been improved. The model is applied to Xiamen waters. Based on extensive survey data, water level elevation, temperature and salinity field along the eastern open boundary and at the Jiulong River inlets and runoffs are analyzed, specified and calibrated. The computed results show good agreement with the measured data, reproduce flooding, emergence of large and complex mudflat region.展开更多
BACKGROUND Gastric adenocarcinoma(GAC)mortality rates have remained relatively changed over the past 30 years,and it continues to be one of the leading causes of cancerrelated death.AIM To search for novel miRNAs rela...BACKGROUND Gastric adenocarcinoma(GAC)mortality rates have remained relatively changed over the past 30 years,and it continues to be one of the leading causes of cancerrelated death.AIM To search for novel miRNAs related to GAC prognosis and further investigate the effect of miR-96-5p on MGC-803 cells.METHODS The miRNA expression profile data of GAC based on The Cancer Genome Atlas were obtained and used to screen differently expressed miRNAs(DEMs)and DEMs related to GAC prognosis.Then,the expression of DEMs related to GAC prognosis was identified in GAC tumor samples and adjacent normal samples by qRT-PCR.The target gene,ZDHHC5,of miR-96-5p was predicted using TargetScan,miRTarBase,and miRDB databases and confirmed by luciferase reporter assay.Furthermore,MGC-803 cells were transfected with inhibitor NC,miR-96-5p inhibitor,si-ZDHHC5,or miR-96-5p inhibitor+si-ZDHHC5,and then cell apoptosis was detected by flow cytometry.The expression of ZDHHC5,Bcl-2,and COX-2 was detected using western blotting.RESULTS A total of 299 DEMs and 35 DEMs related to GAC prognosis were screened based on The Cancer Genome Atlas.Then compared with adjacent normal samples,the levels of miR-96-5p,miR-222-5p,and miR-652-5p were remarkably increased,while miR-125-5p,miR-145-3p,and miR-379-3p levels were reduced in GAC tumor samples(P<0.01),which were consistent with bioinformatics analysis.Furthermore,ZDHHC5 was defined as a direct target gene of miR-96-5p.miR-96-5p inhibition increased the number of apoptotic cells as well as promoted the expression of ZDHHC5,Bcl-2,and COX-2 in MGC-803 cells(P<0.01).After ZDHHC5 inhibition,the number of apoptotic cells and the expression of ZDHHC5,Bcl-2,and COX-2 were reduced.The addition of an miR-96-5p inhibitor partly reversed these effects(P<0.01).CONCLUSION Our findings identified six miRNAs related to GAC prognosis and suggested that downregulated miR-96-5p might induce cell apoptosis via upregulating ZDHHC5 expression in MGC-803 cells.展开更多
This paper revisits the Space-Time Gradient(STG) method which was developed for efficient analysis of unsteady flows due to rotor–stator interaction and presents the method from an alternative time-clocking perspecti...This paper revisits the Space-Time Gradient(STG) method which was developed for efficient analysis of unsteady flows due to rotor–stator interaction and presents the method from an alternative time-clocking perspective. The STG method requires reordering of blade passages according to their relative clocking positions with respect to blades of an adjacent blade row. As the space-clocking is linked to an equivalent time-clocking, the passage reordering can be performed according to the alternative time-clocking. With the time-clocking perspective, unsteady flow solutions from different passages of the same blade row are mapped to flow solutions of the same passage at different time instants or phase angles. Accordingly, the time derivative of the unsteady flow equation is discretized in time directly, which is more natural than transforming the time derivative to a spatial one as with the original STG method. To improve the solution accuracy, a ninth order difference scheme has been investigated for discretizing the time derivative. To achieve a stable solution for the high order scheme, the implicit solution method of Lower-Upper Symmetric GaussSeidel/Gauss-Seidel(LU-SGS/GS) has been employed. The NASA Stage 35 and its blade-countreduced variant are used to demonstrate the validity of the time-clocking based passage reordering and the advantages of the high order difference scheme for the STG method. Results from an existing harmonic balance flow solver are also provided to contrast the two methods in terms of solution stability and computational cost.展开更多
基金his study was supported by the National Natural Science Foundation of China under contract No.40006001.
文摘The difference-ratio relations are introduced to separate tidal constituents that are aliaseddue to the sampling interval and sampling span of the TOPEX/POSEIDON altimeter. It is found that some tidal constituents such as K_1 and SSA, though aliased at along track points, are not aliased at crossover points beeause the data at crossover points are double those at along track points. So the harmonic analysis method can be employed directly for the analysis of time series at crossover points. Then the difference-ratio relations from crossover points are introduced to analyze the time series at along track points. The TOPEX/POSEIDON data in the Northwest Pacific are analyzed with this method. The results from this method agree well with tidal constants from tidal gauges.
基金The research is supported by the National Natural Science Foundation of China(No.11671081)the Fundamental Research Funds for the Central Universities(No.242017K41044).
文摘In this paper,a compact difference scheme is established for the heat equations with multi-point boundary value conditions.The truncation error of the difference scheme is O(τ2+h^4),where t and h are the temporal step size and the spatial step size.A prior estimate of the difference solution in a weighted norm is obtained.The unique solvability,stability and convergence of the difference scheme are proved by the energy method.The theoretical statements for the solution of the difference scheme are supported by numerical examples.
文摘The main harmonic components in nonlinear differential equations can be solved by using the harmonic balance principle. The nonlinear coupling relation among various harmonics can be found by balance theorem of frequency domain. The superhet receiver circuits which are described by nonlinear differential equation of comprising even degree terms include three main harmonic components: the difference frequency and two signal frequencies. Based on the nonlinear coupling relation, taking superhet circuit as an example, this paper demonstrates that the every one of three main harmonics in networks must individually observe conservation of complex power. The power of difference frequency is from variable-frequency device. And total dissipative power of each harmonic is equal to zero. These conclusions can also be verified by the traditional harmonic analysis. The oscillation solutions which consist of the mixture of three main harmonics possess very long oscillation period, the spectral distribution are very tight, similar to evolution from doubling period leading to chaos. It can be illustrated that the chaos is sufficient or infinite extension of the oscillation period. In fact, the oscillation solutions plotted by numerical simulation all are certainly a periodic function of discrete spectrum. When phase portrait plotted hasn’t finished one cycle, it is shown as aperiodic chaos.
文摘Kizmaz [13] studied the difference sequence spaces ∞(A), c(A), and co(A). Several article dealt with the sets of sequences of m-th order difference of which are bounded, convergent, or convergent to zero. Altay and Basar [5] and Altay, Basar, and Mursaleen [7] introduced the Euler sequence spaces e0^r, ec^r, and e∞^r, respectively. The main purpose of this article is to introduce the spaces e0^r△^(m)), ec^r△^(m)), and e∞^r△^(m))consisting of all sequences whose mth order differences are in the Euler spaces e0^r, ec^r, and e∞^r, respectively. Moreover, the authors give some topological properties and inclusion relations, and determine the α-, β-, and γ-duals of the spaces e0^r△^(m)), ec^r△^(m)), and e∞^r△^(m)), and the Schauder basis of the spaces e0^r△^(m)), ec^r△^(m)). The last section of the article is devoted to the characterization of some matrix mappings on the sequence space ec^r△^(m)).
文摘In this article, using generalized weighted mean and difference matrix of order m, we introduce the paranormed sequence space l(u, v, p; △(m)), which consist of the sequences whose generalized weighted △(m)-difference means are in the linear space l(p) defined by I.J.Maddox. Also, we determine the basis of this space and compute its α-, β- and γ-duals. Further, we give the characterization of the classes of matrix mappings from l(u, v, p, △(m)) to l∞, c, and co. Finally, we apply the Hausdorff measure of noncompacness to characterize some classes of compact operators given by matrices on the space lp(U, v, △(m)) (1 ≤ p 〈 ∞).
文摘It is theoretically investigated the generation of higher harmonics of two-dimensional and three-dimensional terahertz electromagnetic beams in nonlinear crystals. The attention is paid to crystalline paraelectrics like SrTiO<sub>3</sub> under the temperatures 60 - 200 K, these crystals possess the cubic nonlinearity. The bias electric field is applied to provide the dominating quadratic nonlinearity. The initial focusing of the beams not only increases the efficiency of generation of higher harmonics, but alto makes possible to select maxima of different higher harmonics at some distances from the input. At lower temperatures the nonlinearity behaves at smaller input amplitudes, whereas at higher temperatures the harmonic generation can be observed at higher frequencies up to 1.5 THz. In three-dimensional beams the peak amplitudes of higher harmonics can be bigger than in two-dimensional beams, but the ratios of these peak values to the maximum values of the focused first harmonic are smaller than in two-dimensional beams.
文摘The quantization of the forced harmonic oscillator is studied with the quantum variable (<em>x</em>, <span style="white-space:nowrap;"><em><sub>v</sub><sup style="margin-left:-8px;">∧</sup></em></span>), with the commutation relation <img src="Edit_28f5b839-7de4-41e5-9ed8-69dc1bf72c2c.bmp" alt="" />, and using a Schr<span style="white-space:nowrap;"><span style="white-space:nowrap;"><span style="white-space:nowrap;">ö</span></span></span>dinger’s like equation on these variable, and associating a linear operator to a constant of motion <em>K</em> (<em>x, v, t</em>) of the classical system, The comparison with the quantization in the space (<em>x, p</em>) is done with the usual Schr<span style="white-space:nowrap;"><span style="white-space:nowrap;"><span style="white-space:nowrap;">ö</span></span></span>dinger’s equation for the Hamiltonian <em>H</em><span style="white-space:normal;">(</span><em style="white-space:normal;">x, p, t</em><span style="white-space:normal;">)</span>, and with the commutation relation <img src="Edit_cca7e318-5b35-4c55-8f09-6089970ce9a2.bmp" alt="" />. It is found that for the non-resonant case, both forms of quantization bring about the same result. However, for the resonant case, both forms of quantization are different, and the probability for the system to be in the exited state for the (<em style="white-space:normal;">x</em><span style="white-space:normal;">, </span><em><sub>v</sub><sup style="margin-left:-8px;">∧</sup></em>) quantization has fewer oscillations than the (<em style="white-space:normal;">x</em><span style="white-space:normal;">, </span><em style="white-space:normal;"><sub>p</sub><sup style="margin-left:-8px;">∧</sup></em>) quantization, the average energy of the system is higher in (<em style="white-space:normal;">x</em><span style="white-space:normal;">, </span><em style="white-space:normal;"><sub>p</sub><sup style="margin-left:-8px;">∧</sup></em>) quantization than on the (<em style="white-space:normal;">x</em><span style="white-space:normal;">, </span><em style="white-space:normal;"><sub>v</sub><sup style="margin-left:-8px;">∧</sup></em>) quantization, and the Boltzmann-Shannon entropy on the (<em style="white-space:normal;">x</em><span style="white-space:normal;">, </span><em style="white-space:normal;"><sub>p</sub><sup style="margin-left:-8px;">∧</sup></em>) quantization is higher than on the (<em style="white-space:normal;">x</em><span style="white-space:normal;">, </span><em style="white-space:normal;"><sub>v</sub><sup style="margin-left:-8px;">∧</sup></em>) quantization.
文摘A semi-implicit and Eulerian - Lagrangian finite difference method for three-dimensionalshallow flow has been extended to a more complete system of equations incorporating second-moment turbulence closure model and transport equations of salinity and temperature. The simulation for flooding and drying of mudflats has been improved. The model is applied to Xiamen waters. Based on extensive survey data, water level elevation, temperature and salinity field along the eastern open boundary and at the Jiulong River inlets and runoffs are analyzed, specified and calibrated. The computed results show good agreement with the measured data, reproduce flooding, emergence of large and complex mudflat region.
文摘BACKGROUND Gastric adenocarcinoma(GAC)mortality rates have remained relatively changed over the past 30 years,and it continues to be one of the leading causes of cancerrelated death.AIM To search for novel miRNAs related to GAC prognosis and further investigate the effect of miR-96-5p on MGC-803 cells.METHODS The miRNA expression profile data of GAC based on The Cancer Genome Atlas were obtained and used to screen differently expressed miRNAs(DEMs)and DEMs related to GAC prognosis.Then,the expression of DEMs related to GAC prognosis was identified in GAC tumor samples and adjacent normal samples by qRT-PCR.The target gene,ZDHHC5,of miR-96-5p was predicted using TargetScan,miRTarBase,and miRDB databases and confirmed by luciferase reporter assay.Furthermore,MGC-803 cells were transfected with inhibitor NC,miR-96-5p inhibitor,si-ZDHHC5,or miR-96-5p inhibitor+si-ZDHHC5,and then cell apoptosis was detected by flow cytometry.The expression of ZDHHC5,Bcl-2,and COX-2 was detected using western blotting.RESULTS A total of 299 DEMs and 35 DEMs related to GAC prognosis were screened based on The Cancer Genome Atlas.Then compared with adjacent normal samples,the levels of miR-96-5p,miR-222-5p,and miR-652-5p were remarkably increased,while miR-125-5p,miR-145-3p,and miR-379-3p levels were reduced in GAC tumor samples(P<0.01),which were consistent with bioinformatics analysis.Furthermore,ZDHHC5 was defined as a direct target gene of miR-96-5p.miR-96-5p inhibition increased the number of apoptotic cells as well as promoted the expression of ZDHHC5,Bcl-2,and COX-2 in MGC-803 cells(P<0.01).After ZDHHC5 inhibition,the number of apoptotic cells and the expression of ZDHHC5,Bcl-2,and COX-2 were reduced.The addition of an miR-96-5p inhibitor partly reversed these effects(P<0.01).CONCLUSION Our findings identified six miRNAs related to GAC prognosis and suggested that downregulated miR-96-5p might induce cell apoptosis via upregulating ZDHHC5 expression in MGC-803 cells.
基金co-supported by the National Natural Science Foundation of China(No.51976172)the National Science and Technology Major Project of China(No.2017-Ⅱ-0009-0023)。
文摘This paper revisits the Space-Time Gradient(STG) method which was developed for efficient analysis of unsteady flows due to rotor–stator interaction and presents the method from an alternative time-clocking perspective. The STG method requires reordering of blade passages according to their relative clocking positions with respect to blades of an adjacent blade row. As the space-clocking is linked to an equivalent time-clocking, the passage reordering can be performed according to the alternative time-clocking. With the time-clocking perspective, unsteady flow solutions from different passages of the same blade row are mapped to flow solutions of the same passage at different time instants or phase angles. Accordingly, the time derivative of the unsteady flow equation is discretized in time directly, which is more natural than transforming the time derivative to a spatial one as with the original STG method. To improve the solution accuracy, a ninth order difference scheme has been investigated for discretizing the time derivative. To achieve a stable solution for the high order scheme, the implicit solution method of Lower-Upper Symmetric GaussSeidel/Gauss-Seidel(LU-SGS/GS) has been employed. The NASA Stage 35 and its blade-countreduced variant are used to demonstrate the validity of the time-clocking based passage reordering and the advantages of the high order difference scheme for the STG method. Results from an existing harmonic balance flow solver are also provided to contrast the two methods in terms of solution stability and computational cost.