Effect of Different Treatment Rapeseeds on Activity of Cellulose Enzyme in Sheep

The purpose of the experiment is to research the effect of different rapeseed treatments feeding on activity of cellulose enzyme in sheep. Eight male adults of semi-fine wool sheep breeds with the same weight and permanent rurnen cannulas were selected according to 4×4 Latin square design to determine the effect of different rapeseed treatment groups including crushed rapeseed, whole rapeseed, extruded rapeseed （dietary lipid content of =67 g·kg^-1） and control group （dietary lipid content of =30 g·kg^-1） on activity dynamic variation of ruminal celluolytic enzyme in sheep. The results showed that ruminal fluid pH matched up to the condition of fiber degradation and growth of cellulolytic bacterium when fed four diets; but there was significant difference （P〈0.05） for the activity of microcrystalline cellulose, glucanase, salicin enzyme involved in ruminal fiber degradation after fed 2, 4, 6 h.

Mutagenicity and Genotoxicity of Organic Extracts from Finished Water with Different Treatment Process

Purification of surface water is widely practiced with conventional water treatment processes like coagulation-flocculation, sedimentation, filtration,and disinfection. Some reports have specified that conventional wastewater purification processes do not effectively remove many chemical contaminants,

Analysis of the Effect of Different Treatment Schemes on Helicobacter Pylori Infection on Improving the Quality of Life of Patients

Objective:To analyze the effect of different treatment schemes on the quality of life of patients with Helicobacter pylori infection.Methods:From June 2019 to November 2020,96 patients with Helicobacter pylori infection were selected and randomly assigned Combined treatment with omeprazole,amoxicillin and clarithromycin was named group A;Group B was treated with omeprazole,amoxicillin,clarithromycin and colloidal bismuth pectin;Group C was given omeprazole,amoxicillin,clarithromycin and metronidazole.Results:The symptom score and gastroscope score of group B or C were lower than those of group A(P<0.05);The incidence of adverse reactions and HP eradication rate in group C were lower than those in group B,and those in group B were lower than those in group A(P<0.05);The quality of life score of group C was higher than that of group B,and that of group B was higher than that of group A,P<0.05.Conclusions:The sequential therapy of omeprazole,amoxicillin,clarithromycin and metronidazole in patients with Helicobacter pylori infection can improve the HP eradication rate,improve the quality of life of patients,which is safe and efficient.

Methane emissions during storage of different treatments from cattle manure in Tianjin

Many studies on methane emissions from animal manure have revealed that animal manure is a major source of methane emissions to the atmosphere that can have negative consequences for people, animals and environment. In general, the release of methane can be influenced by the type of feed taken by animals, temperature, manure characteristics and so on. This study aimed at quantifying and comparing methane release from dairy manure with different piling treatments. Four treatments were designed including manure piling height 30, 45, 60 cm and adding 6 cm manure every day until the piling height was 60 cm. Static chamber method and gas chromatography were adopted to measure the methane emissions from April to June in 2009. Methane emission rates of all four manure treatments were low in the first week and then increased sharply until reaching the peak values. Subsequently, all the methane emission rates decreased and fluctuated within the steady range till the end of the experiment. Wilcoxon nonparametfic tests analysis indicated that methane emission rate was greatly influenced by manure piling height and manner. There were no significant relationships between methane emission rates and the temperatures of ambience and heap. However, regression analysis showed that the quadratic equations were found between emission rates of all treatments and the gas temperature in the barrels.

Effect of intervention treatment from different stages on prognosis in children with central coordination disturbance

BACKGROUND： Central coordination disturbance is regarded as the early-stage symptom of brain injury-induced cerebral palsy. This disease manifests itself as motor disorder, abnormal attitudinal reflex and muscular tension. Early intervention may improve its prognosis. OBJECTIVE： To observe the effects of intervention treatment from different stages on the prognosis of central coordination disturbance following brain injury in children patients. DESIGN： A contrast observation experiment SETTING： Department of Neurology and Rehabilitation, Urumqi Children＇s Hospital PARTICIPANTS ： Totally 151 children who were diagnosed as central coordination disturbance from January 2002 to December 2003 in the Department of Neurology and Rehabilitation of Urumqi Children＇s Hospital were recruited. All the children patients, including 101 male and 50 female, aged from 3 months to 1 year old, met the diagnosis criteria of central coordination disturbance from Vojta. They were divided into slight, moderate and severe abnormity according to Vojta attitudinal reflex. All 151 patients were divided into 2 groups according to their age at diagnosis： 3-6 months old group （n=74）, 62 severe, 10 moderate and 2 slight; 7-12 months old group （n=77）, 66 severe, 7 moderate and 4 slight. All the relatives of children patients were informed of the experiment. METHODS： ① Both groups received physical training （PT） as the main treatment; Hand training was given if necessary. All of the patients received additional hyperbaric oxygen therapy, bioelectric therapy, scalp acupuncture, drug treatment and family training. The importance of integration of hospital and family based rehabilitation was stressed. Those who did not catch up with the normal development or had abnormal reflexes continued to receive treatment. ② Around the age of 2 years old, all children did a final evaluation using Bayley Scales of Infant Development （BSID）. Mental development index （MDI） and physical development index （PDI） were taken as evaluative criteria. Children with scores 80 and above on MDI and PDI were considered to have normal motor and mental development; 79 and below were considered delayers. The Diagnostic Criteria of Cerebral Palsy and Infantecondary School Social Adaptation Scale were used in the final evaluation[scores ≤5 was extremely severe （extremely severe cerebral palsy）, 6 was severe（severe cerebral palsy）, 7 was moderate（moderate cerebral palsy）, 8 was slight（slight cerebral palsy）, 9 was borderline（slight cerebral palsy）, 10 was normal, 11 was above average, 12 was excellent and ≥13 was extremely excellent]. ③ Final evaluative results of 2 groups were compared. And u test was used for the comparison of Bayley development index and Chi-square test for the comparison of normalization rate. MAIN OUTCOME MEASURES： BSID MDI and PDI as well as the normalization rate of motor function and mental behavior of children patients at 2 years old. RESULTS： Totally 151 children patients entered the stage of result analysis. ①Two groups of children patients were given integrated rehabilitation therapy , and evaluated at 2 years old . The 3-6 months old group had higher MDI and PDI than the 7-12 months old group （91.81＋19.99 vs 71.93＋18.98;91.55＋23.61 vs 68.95＋23.51, u=6.265,5.894,P 〈 0.01 ）.②After being given integrated rehabilitation therapy, children patients of 3-6 months old group had significantly higher normalization rate of motor function and mental behavior than 7-12 months old group （73% ,27%,X2=29.723 9,P 〈 0.01 ）. ③Six slight and 17 moderate central coordination disturbance children of 2 groups all completely recovered; After intervention treatment, among 128 severe central coordination disturbance children, 52 recovered and 76 were still abnormal, in which, 43 slight cerebral palsy, 18 moderate cerebral palsy, 5 severe cerebral palsy and 10 extremely severe cerebral palsy. CONCLUSION： To perform integrated intervention treatment before 6 months old can better improve and promote mental and physical development levels of children patients with central coordination disturbance after brain injury than 6 months later.

Cone beam computed tomography-guided differences among registration methods for lung cancer and the effects of tumor position,treatment model,and tumor size on positioning errors

Objective To explore the differences in three different registration methods of cone beam computed tomography(CBCT)-guided down-regulated intense radiation therapy for lung cancer as well as the effects of tumor location,treatment mode,and tumor size on registration.Methods This retrospective analysis included 80 lung cancer patients undergoing radiotherapy in our hospital from November 2017 to October 2019 and compared automatic bone registration,automatic grayscale(t+r)registration,and automatic grayscale(t)positioning error on the X-,Y-,and Z-axes under three types of registration methods.The patients were also grouped according to tumor position,treatment mode,and tumor size to compare positioning errors.Results On the X-,Y-,and Z-axes,automatic grayscale(t+r)and automatic grayscale(t)registration showed a better trend.Analysis of the different treatment modes showed differences in the three registration methods;however,these were not statistically significant.Analysis according to tumor sizes showed significant differences between the three registration methods(P<0.05).Analysis according to tumor positions showed differences in the X-and Y-axes that were not significant(P>0.05),while the autopsy registration in the Z-axis showed the largest difference in the mediastinal and hilar lymph nodes(P<0.05).Conclusion The treatment mode was not the main factor affecting registration error in lung cancer.Three registration methods are available for tumors in the upper and lower lungs measuring<3 cm;among these,automatic gray registration is recommended,while any gray registration method is recommended for tumors located in the mediastinal hilar site measuring<3 cm and in the upper and lower lungs≥3 cm.

浅析喻嘉言《医门法律》燥证辨治之贡献

从秋伤于燥、燥先伤上焦华盖、气血津液脏腑定位、燥病必渴、辨治燥证多从肝肺二脏入手等五个方面对喻嘉言辨治燥证的特点进行梳理,并探索其论治规律,感悟其论燥的独特之处与贡献,以期对现今燥证的预防和治疗有所启迪。

从内伤致痹论治痛风

该文系统总结了治疗痛风的临床经验。笔者认为痛风相当于中医的痹症,其多由内生湿邪致病,以内因论治本病,并根据痛风不同分期对应痹证不同分类加以辨证论治。为中医药治疗痛风提供相应的诊疗方法。

马大正老师治疗经行头痛经验介绍

[目的]探讨马大正老师治疗各型经行头痛的经验。[方法]通过分析马大正老师对经行头痛病因病机的认识、总结马老的临证思路和典型案例,来阐述马大正老师治疗妇科经行头痛的临床经验。[结果]经过马大正老师的中医辨证方法拟方,分别以外感风邪、肝火上逆、血虚生风、痰浊内阻、肝胃不和、气滞血瘀等治疗各型经行头痛,临床取得良好的效果。[结论]引起经行头痛的病因很多,但马老根据患者的特点辨证论治选方用药精准能取得很好的疗效,对临床治疗经行头痛有很好的指导作用。

保守治疗单纯性胸腰椎压缩性骨折的辨证施护

目的:为了研究保守治疗护理单纯性胸腰椎压缩性骨折的临床疗效。方法:选取我院2000年3月～2009年11月120例单纯性胸腰椎压缩性骨折患者,对其进行手法牵引、垫枕、口服中药及功能锻炼等保守治疗和护理。结果:经过保守治疗护理后,有效率100%,功能恢复快,未出现并发症。结论:保守治疗单纯性胸腰椎压缩性骨折效果满意,值得推广应用。

五更泄辨治概述

五更泄,作为一个病名最早见于明代医学家龚廷贤的《寿世宝元》,每于黎明前腹痛作泄,大便稀溏,完谷不化。多由肾虚命门火衰,火不暖土,阴寒湿浊内积所致。其病形成,除责之于肾阳虚,尚与肺金之宣肃、脾之转输、肝之疏泄有密切关系。现从五脏入手,详细地论述病机,并结合7种病因提出了治疗的方法。

老年痴呆症辨治浅识

老年痴呆症是指老年期慢性进行性智能全面衰退性疾病。中医辨证论治,病程较短者,多以实证为主,重在祛痰化瘀,可改善症状,疗效较好;久病,病程长者,常以虚证为主,重在补虚,疗效相对较差。不论是实证或虚证,只要坚持治疗,即可出现逆转佳象,达到一定程度智能恢复的目标。

李士懋教授治疗不寐经验

不寐是以不易入睡、睡后易醒等为主要表现的一种病症,临床主要用安神方药治疗,却多有症状不见好转,使医者倍感无奈。李士懋教授熟谙经典,临证发挥,以脉为辨证中心,首分虚实,治疗不寐有其独到见解。

电针加中药辨证治疗面神经炎临床疗效观察

目的:比较电针加中药、电针和辨证应用中药治疗面神经炎的临床疗效。方法:将120例面神经炎患者随机分成治疗组、电针组及中药组,各40例,各组患者均辨证分型分为风寒袭络、风热灼络、风痰阻络、瘀血阻络4型,治疗组采用电针配合中药治疗;电针组只用电针治疗;中药组只用中药治疗。结果:治疗组、电针组、中药组总有效率经秩和检验,差异有统计学意义(P<0.01)治疗组与电针组比较(P<0.005),治疗组与中药组比较(P<0.001),电针组与中药组比较(P<0.05)。结论:针灸配合中药辨证治疗面神经炎,疗效优于单纯用电针或中药治疗,电针治疗组疗效优于中药组,提示电针加中药治疗面神炎,值得临床推广。

马大正教授治疗闭经新法探析

[目的]探讨马大正教授治疗闭经的独特临床经验。[方法]分析马大正教授对闭经病因病机的认识、治疗闭经独特的辨证论治和精准的选方用药以及典型案例,阐述马大正教授治疗闭经的独特临床经验。[结果]马大正教授治疗闭经方法不同寻常,针对冲任不足、瘀血阻滞、冲气上逆、寒凝瘀滞、湿阻胞脉、痰瘀凝滞、血热煎熬导致的闭经,分别采用补益冲任、磨积导滞、降气导冲、温经散寒、渗利湿浊、软坚散结、清热化瘀等方法,临床取得良好的效果。[结论]马大正教授治疗闭经方法独特,为临床治疗闭经提供了新的思路和方法,值得临床应用推广。

分型辨治震颤麻痹浅述

震颤麻痹又称帕金森病,是一种发生于中老年人常见的锥体外系疾病。临床主要症状为静止性震颤、僵直、运动徐缓及姿势反射丧失等,并有面具脸,头部前倾,躯干俯屈,行走时上肢无摆动及慌张步态等特殊姿态。中医辨证论治可以延缓其病程进展,减轻症状,减少相关西药用量,可提高患者的生活质量。

Network pharmacology unveils spleen-fortifying effect of Codonopsis Radix on different gastric diseases based on theory of “same treatment for different diseases” in traditional Chinese medicine

Objective: "Same treatment for different diseases" is a unique treatment strategy under the guidance of traditional Chinese medicine(TCM) theory.Codonopsis Radix(Codonopsis pilosula,Dangshen in Chinese)with spleen-fortifying effect was employed to understand the strategy of "Same treatment for different diseases",based on its common mechanism in the treatment of gastric diseases including gastric ulcer,gastritis and gastric cancer via network pharmacology research.Methods:Network pharmacology research methods were used to analyze the interaction network and potential mechanisms of Dangshen in treating gastric ulcer,gastritis and gastric cancer.The active components and their target proteins of Dangshen were integrated from TCMSP,BATMAN-TCM databases.The targets of gastric ulcer,gastritis and gastric cancer were collected through GeneCards,PubMed,TDD and DisGeNET Database.Through screening,the key components and the key targets of Dangshen in treating gastric ulcer,gastritis and gastric cancer were obtained.After KEGG pathway analysis and GO analysis,the important pathways and biological processes were analyzed.Results:Through data and literature mining,the common and specific pharmaceutical effects and mechanism of Dangshen were summarized in these three gastric lesions.It was shown that Dangshen mainly acted on gastric ulcer,gastritis and gastric cancer through the overall regulation of the PI3K-AkT signaling pathway.With the development of the disease,it will gradually increase the control of inflammation through TNF,NF-κB and other inflammation-related signaling pathways to reduce inflammatory damage.For tumorigenesis,it pays more attention to inhibiting the ErbB signaling pathways to reduce the proliferation and migration of tumor cells.In addition,Dangshen's regulation of HIF-1 signaling pathway may also be beneficial for the treatment of gastric ulcer,gastritis and gastric cancer.Conclusion:Dangshen achieves spleen-fortifying effect on gastric diseases including gastric ulcer,gastritis and gastric cancer through multiple targets in multiple pathways,especially PI3K-AKT pathway and HIF-1 pathway.It could provide a scientific basis for understanding the strategy of "Same treatment for different diseases" in traditional Chinese medicine.

Text Mining of Rheumatoid Arthritis and Diabetes Mellitus to Understand the Mechanisms of Chinese Medicine in Different Diseases with Same Treatment

Objective： To identify the commonalities between rheumatoid arthritis （RA） and diabetes mellitus （DM） to understand the mechanisms of Chinese medicine （CM） in different diseases with the same treatment. Methods： A text mining approach was adopted to analyze the commonalities between RA and DM according to CM and biological elements. The major commonalities were subsequently verified in RA and DM rat models, in which herbal formula for the treatment of both RA and DM identified via text mining was used as the intervention. Results： Similarities were identified between RA and DM regarding the CM approach used for diagnosis and treatment, as well as the networks of biological activities affected by each disease, including the involvement of adhesion molecules, oxidative stress, cytokines, T-lymphocytes, apoptosis, and inflammation. The Ramulus Cinnamomi-Radix Paeoniae Alba-Rhizoma Anemarrhenae is an herbal combination used to treat RA and DM. This formula demonstrated similar effects on oxidative stress and inflammation in rats with collagen-induced arthritis, which supports the text mining results regarding the commonalities between RA and DM. Conclusion： Commonalities between the biological activities involved in RA and DM were identified through text mining, and both RA and DM might be responsive to the same intervention at a specific stage.