As digital technologies have advanced more rapidly,the number of paper documents recently converted into a digital format has exponentially increased.To respond to the urgent need to categorize the growing number of d...As digital technologies have advanced more rapidly,the number of paper documents recently converted into a digital format has exponentially increased.To respond to the urgent need to categorize the growing number of digitized documents,the classification of digitized documents in real time has been identified as the primary goal of our study.A paper classification is the first stage in automating document control and efficient knowledge discovery with no or little human involvement.Artificial intelligence methods such as Deep Learning are now combined with segmentation to study and interpret those traits,which were not conceivable ten years ago.Deep learning aids in comprehending input patterns so that object classes may be predicted.The segmentation process divides the input image into separate segments for a more thorough image study.This study proposes a deep learning-enabled framework for automated document classification,which can be implemented in higher education.To further this goal,a dataset was developed that includes seven categories:Diplomas,Personal documents,Journal of Accounting of higher education diplomas,Service letters,Orders,Production orders,and Student orders.Subsequently,a deep learning model based on Conv2D layers is proposed for the document classification process.In the final part of this research,the proposed model is evaluated and compared with other machine-learning techniques.The results demonstrate that the proposed deep learning model shows high results in document categorization overtaking the other machine learning models by reaching 94.84%,94.79%,94.62%,94.43%,94.07%in accuracy,precision,recall,F-score,and AUC-ROC,respectively.The achieved results prove that the proposed deep model is acceptable to use in practice as an assistant to an office worker.展开更多
Numerous hydrocarbon accumulations are found in ramp crest shoals worldwide and therefore this depositional setting has a high potential of being the hydrocarbon reservoir. In this paper, we combined digital outcrop g...Numerous hydrocarbon accumulations are found in ramp crest shoals worldwide and therefore this depositional setting has a high potential of being the hydrocarbon reservoir. In this paper, we combined digital outcrop geology and traditional geological mapping to build an outcrop-based geocellular model of the ramp-crest shoal complex of the Lower Triassic Feixianguan Formation in the Eastern Sichuan Basin. The outcrop model serves as an analogue for the subsurface reservoir of the Feixianguan Formation and illustrates the complexity of the lithofacies types, stratigraphic architecture, and reservoir heterogeneities at a scale below conventional subsurface data resolution. The studied ramp -crest shoal complex consists of thirteen types of lithofacies that can be grouped into three facies-groups corresponding to subtidal intraclastic shoal, sub- to inter-tidal oolitic shoal, and tidal flat depositional environments respectively. The stratigraphic architecture of the shoal complex shows mostly a strong progradation of the high energy facies associated with an overall decrease of accommodation space associated with relative sea level still stand. Two reservoir facies associations have been recognized. The first one consists of supratidai dolomudstone and upper intertidal partially dolomitized oolitic packstone with anhydrite or nodules. These facies were deposited above the high energy oolitic grainstones and occurs as thin-bedded and laterally continuous layers, characterized by high porosity and low permeability. The second reservoir facies association is composed of intertidal crystalline dolomite and subtidal intraclastic bindstone that occurs stratigraphically below the oolitic grainstones. These deposits consist of massive laterally discontinuously beds, and are characterized by high porosity and high permeability. Both types of reservoir facies tend to be stacked vertically and migrated laterally with the progradation of the shoal complex. The construction of the outcrop-based 3D geological model provide a description and quantification of the facies distribution within a robust stratigraphic framework and the style and amount of reservoir heterogeneities associated with a ramp-crest shoal complex reservoir such as the one found in Lower Triassic Feixianguan Formation and Cambrian Longwangmiao Formation in Sichuan Basin or other ramp-crest reservoir worldwide.展开更多
According to the principle of meshing engagement and the theory of the digitized conjugate surface, this paper applies the software Conjugater-1.0 that is developed by ourselves to compute, respectively, the digitized...According to the principle of meshing engagement and the theory of the digitized conjugate surface, this paper applies the software Conjugater-1.0 that is developed by ourselves to compute, respectively, the digitized conjugate curved surfaces of the straight-tooth surface and drum-tooth surface, which will establish the theoretical and technical foundation for digitized engaging analysis, simulation, and digitized manufacturing technology of the diversified gears.展开更多
In this paper, we present an ultrafast digitizer utilizing the DRS4 switched capacitor array applicationspecific integrated circuit to achieve an ultrafast sampling speed of at most 5 GS/s. We cascaded all eight chann...In this paper, we present an ultrafast digitizer utilizing the DRS4 switched capacitor array applicationspecific integrated circuit to achieve an ultrafast sampling speed of at most 5 GS/s. We cascaded all eight channels(sub-channels) of a single DRS4 chip for increased storage depth. The digitizer contains four DRS4 chips, a quadchannel analog-to-digital converter,a controlling fieldprogrammable gate array, a PXI interface, and an SFP+connector. Consequently, each DRS4 channel has a depth of 8192 points and a vertical resolution of 14 bits. The readout sequences should be broken into several segments and then reordered to obtain the correct sequential data sets, and this offline procedure varies in different readout modes. This paper describes the design and implementation of the hardware;in particular, the respective processing procedures are described in detail. Furthermore, the offset error is calibrated and corrected to improve the precision of the captured waveform in both single-channel and highresolution modes.展开更多
In order to meet the needs of designing and processing digitized surfaces, the method to spreading digitized surface has been proposed. The key technique is to solve the problem of digitized conjugate surface. In the ...In order to meet the needs of designing and processing digitized surfaces, the method to spreading digitized surface has been proposed. The key technique is to solve the problem of digitized conjugate surface. In the paper, the digitized conjugate surface was theoretically investigated, and the solution of conjugate surface based on digitized surface was also studied. The digitized conjugate surface theory was then proposed, and applied to build the model of solving conjugate surface based on digitized surface. A corresponding algorithm was developed. This paper applies the software Conjugater-1.0 that is developed by ourselves to compute the digitized conjugate surfaces of the drum-tooth surface. This study provides theoretical and technical bases for analyzing engagement of digitized surface, simulation and numerical processing technique. Key words digitized conjugate surface - generating method - simulation CLC number O 186.1 - TH 122 Foundation item: Supported by the National Natural Science Foundation of China (50075031)Biography: Xiao Lai-yuan (1957-), male, Professor, Ph. D candidate, research direction: machanical design & theory, digital technology展开更多
The global description uses composition, transition and distribution to describe an amino acid sequence and has been widely adopted in various fields. Here we integrate it with properties of nucleic acid and form a ne...The global description uses composition, transition and distribution to describe an amino acid sequence and has been widely adopted in various fields. Here we integrate it with properties of nucleic acid and form a new method to digitize DNA sequence. Through this method we can use a 39-dimession vector to represent a DNA sequence. We use the exon-1 of β-Globin genes of eight species to verify this method and compare with other methods. A similar result with other method proves that this method is persuading. This method provides a new strategy to digitize DNA sequence and generates DNA sequence descriptor vector. It is different from other methods and this method only produces a 39-dimession vector and not depends on the length of DNA sequence.展开更多
Reverse engineering in the manufacturing field is a process in which the digitized data are obtained from an existing object model or a part of it, and then the CAD model is reconstructed. This paper presents an RBF n...Reverse engineering in the manufacturing field is a process in which the digitized data are obtained from an existing object model or a part of it, and then the CAD model is reconstructed. This paper presents an RBF neural network approach to modify and fit the digitized data. The centers for the RBF are selected by using the orthogonal least squares learning algorithm. A mathematically known surface is used for generating a number of samples for training the networks. The trained networks then generated a number of new points which were compared with the calculating points from the equations. Moreover, a series of practice digitizing curves are used to test the approach. The results showed that this approach is effective in modifying and fitting digitized data and generating data points to reconstruct the surface model.展开更多
Metric measurement of digitized shapes is commonly applied in optical measuring systems.In this letter,three shape-related factors defined by the authors are used in the construction of amultiple linear regression mod...Metric measurement of digitized shapes is commonly applied in optical measuring systems.In this letter,three shape-related factors defined by the authors are used in the construction of amultiple linear regression model which is utilized to compute the circumference of the convex shapes inmillimeter unit.The model is first built upon the relationship hypothesis and then its adequacy ismathematically validated.The results of applying the developed model to the given number of convexshapes in a finite circumferential length range suggest that,in terms of percent error,the model pre-cision is to satisfaction by being within±4%.The test also shows the model’s robustness against theshape’s orientation anisotropy.展开更多
Archaeological excavation involves disintegration, removal, and reassembly of the archaeological record;as such it is considered by many to be an unrepeatable, destructive activity. This perception has contributed to ...Archaeological excavation involves disintegration, removal, and reassembly of the archaeological record;as such it is considered by many to be an unrepeatable, destructive activity. This perception has contributed to an advancement in archaeological practice, namely, the development of computerized recording systems that digitally record archaeological excavations spatially and volumetrically during fieldwork. This paper is concerned with those archaeological sites where digital field recording has not been done. These sites, recorded by traditional methods, should not be excluded from attempts to restructure the spatial, volumetric, and stratigraphic archaeological data. A thorough methodology for the conversion of traditional records into digitized data is presented, including the detailed procedures required for three-dimensional plotting of recorded data—both the excavated material and the drawn site maps and cross-sections. Finally, the use of these methods is demonstrated on a complex Early to Middle Pleistocene site, illustrating the benefits of digitization and three-dimensional reconstruction in resolving stratigraphic and spatial questions.展开更多
Antibiotic abuse now poses a grave threat to global ecology and bestirs public concerns about the residue issue in daily necessities.The traceability measurements along supply chain or logistic circulation have become...Antibiotic abuse now poses a grave threat to global ecology and bestirs public concerns about the residue issue in daily necessities.The traceability measurements along supply chain or logistic circulation have become increasingly essential given the labile nature of diverse synthetic residuals on site.In an attempt to answer this urgency,here a miniaturized fluorometric aptasensor prototype was contrived that catered to the point-of-care screening norm for two typical additives:chloramphenicol and enrofloxacin.The key target-indicating module worked in vitro based on the competitive binding-induced fluorescence recovery of fluorescein-labeled aptamers,which were photobleached beforehand in the format of double helix on burlike nanogold carriers.The“prickly”geometry of the latter not just enriched the capture probes at preferentially substrate-accessible spires;but also contributed to a tip-enhanced surface plasmon effect,sensitizing the signal-on during the duplex dissociation even at nanomolar threshold of the analytes.On the other hand,to encompass a full portable,a set of optical devices were mounted within a 3D-printed cartridge(adaptor)to converge the light beam and route it towards the detector,for which the smartphone camera came up in handy with a home-developed App for calibrating the emissive brightness.Enlightened by the high-dynamic-range compression,an imaging diagnostic algorithm was built in to grid and digitize each slide in the album for augmented detection performance.Thus,a novel bio-to-silico integration was invented that capable of in situ rapid reporting on the antibiotic presence with high sensitivity and selectivity.Further field practices in spiked milk on sales proved the precision and rudimentary feasibility of the well-assembled model of appliance,thus holding nice prospects in nonexpert(e.g.,family and local community)utilities for foodborne antibiotic identification.展开更多
This paper described the principle of digitized chromatographic fingerprint spectrum and established digitized chromatographic fingerprint spectra of ten brands of Chinese famous tea by the micellar electrokinetic chr...This paper described the principle of digitized chromatographic fingerprint spectrum and established digitized chromatographic fingerprint spectra of ten brands of Chinese famous tea by the micellar electrokinetic chromatography. This work was done using a 25 mmol·L -1 sodium dodecylsulfate in a 20 mmol·L -1 borate (pH 7 0) solution as running buffer, 20 kV applied potential and detection at 280 nm. The chromatographic fingerprint spectra were digitized by the relative retention value ( α ) and the relative area ( S r), and were analyzed to identify the tea samples. In the absence of the standard samples, the present method was easy setup and inexpensive, and provided the applicable information for the quality assessment of teas.展开更多
The photoneutron source (PNS, phase 1), an electron linear accelerator (linac)-based pulsed neutron facility that uses the time-of-flight (TOF) technique, was constructed for the acquisition of nuclear data from...The photoneutron source (PNS, phase 1), an electron linear accelerator (linac)-based pulsed neutron facility that uses the time-of-flight (TOF) technique, was constructed for the acquisition of nuclear data from the Thorium Molten Salt Reactor (TMSR) at the Shanghai Institute of Applied Physics (SINAP). The neutron detector signal used for TOF calculation, with information on the pulse arrival time, pulse shape, and pulse height, was recorded by using a waveform digitizer (WFD). By using the pulse height and pulse-shape discrimination (PSD) analysis to identify neutrons and "y-rays, the neutron TOF spectrum was obtained by employing a simple electronic design, and a new WFD-based DAQ system was developed and tested in this commissioning experiment. The DAQ system developed is characterized by a very high efficiency with respect to millisecond neutron TOF spectroscopy.展开更多
Guo Wei, President and CEO of Digital China, answers questions about the company's operating strategies and prospects for China's IT service sector in a written interview with Beijing Review. Beijing Review: D...Guo Wei, President and CEO of Digital China, answers questions about the company's operating strategies and prospects for China's IT service sector in a written interview with Beijing Review. Beijing Review: Digital China has detailed its strategies as "IT Serves China" and "IT Service on Demand." What is the operating objective for 2006?展开更多
Background High-voltage analog X-ray examination is a main tool for pneumoconiosis,which is challenged by digital radiography (DR).The tube voltage of DR chest films required for diagnosis and staging of pneumoconio...Background High-voltage analog X-ray examination is a main tool for pneumoconiosis,which is challenged by digital radiography (DR).The tube voltage of DR chest films required for diagnosis and staging of pneumoconiosis is concerned technically.We investigated the influence of the tube voltage on chest X-ray DR image quality of patients exposed to occupational dust.Methods DR images of the CDRAD2.0model,an anatomical chest phantom,and 136 exposed workers were analyzed at different tube voltages by threereaders.Image quality factors (IQF) were calculated and compared using the CDRAD2.0 model.DR images of ten anatomic positions were scored against those of the high-kilovolt chest films in anatomical phantom and clinical cases,and differences in scores were analyzed.Results In the CDRAD2.0 model,all three readers had a minimal IQF at 120 kV (mean:22.25 kV).The differences in the mean IQF of DR images at different tube voltages was significant (F=13.78,P〈0.001).The IQF of DR imaging at 120 kV was similar to high kilovolt analog imaging (t=-0.58,P〉0.05).In the anatomic phantom and clinical cases,the DR images at 120 kV were closest in anatomical detail to the high W analog images,and the means were similar (P〉0.05).Conclusions Among different tube voltages,DR image quality is closest to the high kilovolt analog images at 120 kV in patients exposed to occupational dust.展开更多
The technology of drilling tests makes it possible to obtain the strength parameter of rock accurately in situ. In this paper, a new rock cutting analysis model that considers the influence of the rock crushing zone(R...The technology of drilling tests makes it possible to obtain the strength parameter of rock accurately in situ. In this paper, a new rock cutting analysis model that considers the influence of the rock crushing zone(RCZ) is built. The formula for an ultimate cutting force is established based on the limit equilibrium principle. The relationship between digital drilling parameters(DDP) and the c-φ parameter(DDP-cφ formula, where c refers to the cohesion and φ refers to the internal friction angle) is derived, and the response of drilling parameters and cutting ratio to the strength parameters is analyzed. The drillingbased measuring method for the c-φ parameter of rock is constructed. The laboratory verification test is then completed, and the difference in results between the drilling test and the compression test is less than 6%. On this basis, in-situ rock drilling tests in a traffic tunnel and a coal mine roadway are carried out, and the strength parameters of the surrounding rock are effectively tested. The average difference ratio of the results is less than 11%, which verifies the effectiveness of the proposed method for obtaining the strength parameters based on digital drilling. This study provides methodological support for field testing of rock strength parameters.展开更多
A digital data-acquisition system based on XIA LLC products was used in a complex nuclear reaction experiment using radioactive ion beams.A flexible trigger system based on a field-programmable gate array(FPGA)paramet...A digital data-acquisition system based on XIA LLC products was used in a complex nuclear reaction experiment using radioactive ion beams.A flexible trigger system based on a field-programmable gate array(FPGA)parametrization was developed to adapt to different experimental sizes.A user-friendly interface was implemented,which allows converting script language expressions into FPGA internal control parameters.The proposed digital system can be combined with a conventional analog data acquisition system to provide more flexibility.The performance of the combined system was veri-fied using experimental data.展开更多
文摘As digital technologies have advanced more rapidly,the number of paper documents recently converted into a digital format has exponentially increased.To respond to the urgent need to categorize the growing number of digitized documents,the classification of digitized documents in real time has been identified as the primary goal of our study.A paper classification is the first stage in automating document control and efficient knowledge discovery with no or little human involvement.Artificial intelligence methods such as Deep Learning are now combined with segmentation to study and interpret those traits,which were not conceivable ten years ago.Deep learning aids in comprehending input patterns so that object classes may be predicted.The segmentation process divides the input image into separate segments for a more thorough image study.This study proposes a deep learning-enabled framework for automated document classification,which can be implemented in higher education.To further this goal,a dataset was developed that includes seven categories:Diplomas,Personal documents,Journal of Accounting of higher education diplomas,Service letters,Orders,Production orders,and Student orders.Subsequently,a deep learning model based on Conv2D layers is proposed for the document classification process.In the final part of this research,the proposed model is evaluated and compared with other machine-learning techniques.The results demonstrate that the proposed deep learning model shows high results in document categorization overtaking the other machine learning models by reaching 94.84%,94.79%,94.62%,94.43%,94.07%in accuracy,precision,recall,F-score,and AUC-ROC,respectively.The achieved results prove that the proposed deep model is acceptable to use in practice as an assistant to an office worker.
基金supported by grants from the National Key Oil and Gas Program of China(No.2016ZX05004002)from Special Program of PetroChina(No.2014E-32-02)
文摘Numerous hydrocarbon accumulations are found in ramp crest shoals worldwide and therefore this depositional setting has a high potential of being the hydrocarbon reservoir. In this paper, we combined digital outcrop geology and traditional geological mapping to build an outcrop-based geocellular model of the ramp-crest shoal complex of the Lower Triassic Feixianguan Formation in the Eastern Sichuan Basin. The outcrop model serves as an analogue for the subsurface reservoir of the Feixianguan Formation and illustrates the complexity of the lithofacies types, stratigraphic architecture, and reservoir heterogeneities at a scale below conventional subsurface data resolution. The studied ramp -crest shoal complex consists of thirteen types of lithofacies that can be grouped into three facies-groups corresponding to subtidal intraclastic shoal, sub- to inter-tidal oolitic shoal, and tidal flat depositional environments respectively. The stratigraphic architecture of the shoal complex shows mostly a strong progradation of the high energy facies associated with an overall decrease of accommodation space associated with relative sea level still stand. Two reservoir facies associations have been recognized. The first one consists of supratidai dolomudstone and upper intertidal partially dolomitized oolitic packstone with anhydrite or nodules. These facies were deposited above the high energy oolitic grainstones and occurs as thin-bedded and laterally continuous layers, characterized by high porosity and low permeability. The second reservoir facies association is composed of intertidal crystalline dolomite and subtidal intraclastic bindstone that occurs stratigraphically below the oolitic grainstones. These deposits consist of massive laterally discontinuously beds, and are characterized by high porosity and high permeability. Both types of reservoir facies tend to be stacked vertically and migrated laterally with the progradation of the shoal complex. The construction of the outcrop-based 3D geological model provide a description and quantification of the facies distribution within a robust stratigraphic framework and the style and amount of reservoir heterogeneities associated with a ramp-crest shoal complex reservoir such as the one found in Lower Triassic Feixianguan Formation and Cambrian Longwangmiao Formation in Sichuan Basin or other ramp-crest reservoir worldwide.
文摘According to the principle of meshing engagement and the theory of the digitized conjugate surface, this paper applies the software Conjugater-1.0 that is developed by ourselves to compute, respectively, the digitized conjugate curved surfaces of the straight-tooth surface and drum-tooth surface, which will establish the theoretical and technical foundation for digitized engaging analysis, simulation, and digitized manufacturing technology of the diversified gears.
文摘In this paper, we present an ultrafast digitizer utilizing the DRS4 switched capacitor array applicationspecific integrated circuit to achieve an ultrafast sampling speed of at most 5 GS/s. We cascaded all eight channels(sub-channels) of a single DRS4 chip for increased storage depth. The digitizer contains four DRS4 chips, a quadchannel analog-to-digital converter,a controlling fieldprogrammable gate array, a PXI interface, and an SFP+connector. Consequently, each DRS4 channel has a depth of 8192 points and a vertical resolution of 14 bits. The readout sequences should be broken into several segments and then reordered to obtain the correct sequential data sets, and this offline procedure varies in different readout modes. This paper describes the design and implementation of the hardware;in particular, the respective processing procedures are described in detail. Furthermore, the offset error is calibrated and corrected to improve the precision of the captured waveform in both single-channel and highresolution modes.
文摘In order to meet the needs of designing and processing digitized surfaces, the method to spreading digitized surface has been proposed. The key technique is to solve the problem of digitized conjugate surface. In the paper, the digitized conjugate surface was theoretically investigated, and the solution of conjugate surface based on digitized surface was also studied. The digitized conjugate surface theory was then proposed, and applied to build the model of solving conjugate surface based on digitized surface. A corresponding algorithm was developed. This paper applies the software Conjugater-1.0 that is developed by ourselves to compute the digitized conjugate surfaces of the drum-tooth surface. This study provides theoretical and technical bases for analyzing engagement of digitized surface, simulation and numerical processing technique. Key words digitized conjugate surface - generating method - simulation CLC number O 186.1 - TH 122 Foundation item: Supported by the National Natural Science Foundation of China (50075031)Biography: Xiao Lai-yuan (1957-), male, Professor, Ph. D candidate, research direction: machanical design & theory, digital technology
文摘The global description uses composition, transition and distribution to describe an amino acid sequence and has been widely adopted in various fields. Here we integrate it with properties of nucleic acid and form a new method to digitize DNA sequence. Through this method we can use a 39-dimession vector to represent a DNA sequence. We use the exon-1 of β-Globin genes of eight species to verify this method and compare with other methods. A similar result with other method proves that this method is persuading. This method provides a new strategy to digitize DNA sequence and generates DNA sequence descriptor vector. It is different from other methods and this method only produces a 39-dimession vector and not depends on the length of DNA sequence.
文摘Reverse engineering in the manufacturing field is a process in which the digitized data are obtained from an existing object model or a part of it, and then the CAD model is reconstructed. This paper presents an RBF neural network approach to modify and fit the digitized data. The centers for the RBF are selected by using the orthogonal least squares learning algorithm. A mathematically known surface is used for generating a number of samples for training the networks. The trained networks then generated a number of new points which were compared with the calculating points from the equations. Moreover, a series of practice digitizing curves are used to test the approach. The results showed that this approach is effective in modifying and fitting digitized data and generating data points to reconstruct the surface model.
基金the Ningbo Natural Science Foundation(No.2006A610016)the Foundation of National EducationMinistry for Returned Overseas Students&Scholars(SRFfor ROCS,SEM.No.2006699).
文摘Metric measurement of digitized shapes is commonly applied in optical measuring systems.In this letter,three shape-related factors defined by the authors are used in the construction of amultiple linear regression model which is utilized to compute the circumference of the convex shapes inmillimeter unit.The model is first built upon the relationship hypothesis and then its adequacy ismathematically validated.The results of applying the developed model to the given number of convexshapes in a finite circumferential length range suggest that,in terms of percent error,the model pre-cision is to satisfaction by being within±4%.The test also shows the model’s robustness against theshape’s orientation anisotropy.
文摘Archaeological excavation involves disintegration, removal, and reassembly of the archaeological record;as such it is considered by many to be an unrepeatable, destructive activity. This perception has contributed to an advancement in archaeological practice, namely, the development of computerized recording systems that digitally record archaeological excavations spatially and volumetrically during fieldwork. This paper is concerned with those archaeological sites where digital field recording has not been done. These sites, recorded by traditional methods, should not be excluded from attempts to restructure the spatial, volumetric, and stratigraphic archaeological data. A thorough methodology for the conversion of traditional records into digitized data is presented, including the detailed procedures required for three-dimensional plotting of recorded data—both the excavated material and the drawn site maps and cross-sections. Finally, the use of these methods is demonstrated on a complex Early to Middle Pleistocene site, illustrating the benefits of digitization and three-dimensional reconstruction in resolving stratigraphic and spatial questions.
基金supported by National Natural Science Foundation of China(Nos.21874071 and 22204077)China Postdoctoral Science Foundation(No.2021M701722)Fundamental Research Funds for the Central Universities(Nos.30921013112 and 30922010501)。
文摘Antibiotic abuse now poses a grave threat to global ecology and bestirs public concerns about the residue issue in daily necessities.The traceability measurements along supply chain or logistic circulation have become increasingly essential given the labile nature of diverse synthetic residuals on site.In an attempt to answer this urgency,here a miniaturized fluorometric aptasensor prototype was contrived that catered to the point-of-care screening norm for two typical additives:chloramphenicol and enrofloxacin.The key target-indicating module worked in vitro based on the competitive binding-induced fluorescence recovery of fluorescein-labeled aptamers,which were photobleached beforehand in the format of double helix on burlike nanogold carriers.The“prickly”geometry of the latter not just enriched the capture probes at preferentially substrate-accessible spires;but also contributed to a tip-enhanced surface plasmon effect,sensitizing the signal-on during the duplex dissociation even at nanomolar threshold of the analytes.On the other hand,to encompass a full portable,a set of optical devices were mounted within a 3D-printed cartridge(adaptor)to converge the light beam and route it towards the detector,for which the smartphone camera came up in handy with a home-developed App for calibrating the emissive brightness.Enlightened by the high-dynamic-range compression,an imaging diagnostic algorithm was built in to grid and digitize each slide in the album for augmented detection performance.Thus,a novel bio-to-silico integration was invented that capable of in situ rapid reporting on the antibiotic presence with high sensitivity and selectivity.Further field practices in spiked milk on sales proved the precision and rudimentary feasibility of the well-assembled model of appliance,thus holding nice prospects in nonexpert(e.g.,family and local community)utilities for foodborne antibiotic identification.
文摘This paper described the principle of digitized chromatographic fingerprint spectrum and established digitized chromatographic fingerprint spectra of ten brands of Chinese famous tea by the micellar electrokinetic chromatography. This work was done using a 25 mmol·L -1 sodium dodecylsulfate in a 20 mmol·L -1 borate (pH 7 0) solution as running buffer, 20 kV applied potential and detection at 280 nm. The chromatographic fingerprint spectra were digitized by the relative retention value ( α ) and the relative area ( S r), and were analyzed to identify the tea samples. In the absence of the standard samples, the present method was easy setup and inexpensive, and provided the applicable information for the quality assessment of teas.
基金Supported by Strategic Priority Research Program of the Chinese Academy of Science(TMSR)(XDA02010100)National Natural Science Foundation of China(NSFC)(11475245,No.11305239)Shanghai Key Laboratory of Particle Physics and Cosmology(11DZ2260700)
文摘The photoneutron source (PNS, phase 1), an electron linear accelerator (linac)-based pulsed neutron facility that uses the time-of-flight (TOF) technique, was constructed for the acquisition of nuclear data from the Thorium Molten Salt Reactor (TMSR) at the Shanghai Institute of Applied Physics (SINAP). The neutron detector signal used for TOF calculation, with information on the pulse arrival time, pulse shape, and pulse height, was recorded by using a waveform digitizer (WFD). By using the pulse height and pulse-shape discrimination (PSD) analysis to identify neutrons and "y-rays, the neutron TOF spectrum was obtained by employing a simple electronic design, and a new WFD-based DAQ system was developed and tested in this commissioning experiment. The DAQ system developed is characterized by a very high efficiency with respect to millisecond neutron TOF spectroscopy.
文摘Guo Wei, President and CEO of Digital China, answers questions about the company's operating strategies and prospects for China's IT service sector in a written interview with Beijing Review. Beijing Review: Digital China has detailed its strategies as "IT Serves China" and "IT Service on Demand." What is the operating objective for 2006?
文摘Background High-voltage analog X-ray examination is a main tool for pneumoconiosis,which is challenged by digital radiography (DR).The tube voltage of DR chest films required for diagnosis and staging of pneumoconiosis is concerned technically.We investigated the influence of the tube voltage on chest X-ray DR image quality of patients exposed to occupational dust.Methods DR images of the CDRAD2.0model,an anatomical chest phantom,and 136 exposed workers were analyzed at different tube voltages by threereaders.Image quality factors (IQF) were calculated and compared using the CDRAD2.0 model.DR images of ten anatomic positions were scored against those of the high-kilovolt chest films in anatomical phantom and clinical cases,and differences in scores were analyzed.Results In the CDRAD2.0 model,all three readers had a minimal IQF at 120 kV (mean:22.25 kV).The differences in the mean IQF of DR images at different tube voltages was significant (F=13.78,P〈0.001).The IQF of DR imaging at 120 kV was similar to high kilovolt analog imaging (t=-0.58,P〉0.05).In the anatomic phantom and clinical cases,the DR images at 120 kV were closest in anatomical detail to the high W analog images,and the means were similar (P〉0.05).Conclusions Among different tube voltages,DR image quality is closest to the high kilovolt analog images at 120 kV in patients exposed to occupational dust.
基金supported by the National Key Research and Development Program of China(No.2023YFC2907600)the National Natural Science Foundation of China(Nos.42077267,42277174 and 52074164)+2 种基金the Natural Science Foundation of Shandong Province,China(No.ZR2020JQ23)the Opening Project of State Key Laboratory of Explosion Science and Technology,Beijing Institute of Technology(No.KFJJ21-02Z)the Fundamental Research Funds for the Central Universities,China(No.2022JCCXSB03).
文摘The technology of drilling tests makes it possible to obtain the strength parameter of rock accurately in situ. In this paper, a new rock cutting analysis model that considers the influence of the rock crushing zone(RCZ) is built. The formula for an ultimate cutting force is established based on the limit equilibrium principle. The relationship between digital drilling parameters(DDP) and the c-φ parameter(DDP-cφ formula, where c refers to the cohesion and φ refers to the internal friction angle) is derived, and the response of drilling parameters and cutting ratio to the strength parameters is analyzed. The drillingbased measuring method for the c-φ parameter of rock is constructed. The laboratory verification test is then completed, and the difference in results between the drilling test and the compression test is less than 6%. On this basis, in-situ rock drilling tests in a traffic tunnel and a coal mine roadway are carried out, and the strength parameters of the surrounding rock are effectively tested. The average difference ratio of the results is less than 11%, which verifies the effectiveness of the proposed method for obtaining the strength parameters based on digital drilling. This study provides methodological support for field testing of rock strength parameters.
基金This work was supported by the National Key R&D Program of China(Nos.2023YFA1606403 and 2023YFE0101600)the National Natural Science Foundation of China(Nos.12027809,11961141003,U1967201,11875073 and 11875074).
文摘A digital data-acquisition system based on XIA LLC products was used in a complex nuclear reaction experiment using radioactive ion beams.A flexible trigger system based on a field-programmable gate array(FPGA)parametrization was developed to adapt to different experimental sizes.A user-friendly interface was implemented,which allows converting script language expressions into FPGA internal control parameters.The proposed digital system can be combined with a conventional analog data acquisition system to provide more flexibility.The performance of the combined system was veri-fied using experimental data.