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Correction:Nanomaterial-Based Repurposing of Macrophage Metabolism and Its Applications 被引量:1
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作者 Tingting Meng Danfeng He +7 位作者 Zhuolei Han Rong Shi Yuhan Wang Bibo Ren Cheng Zhang Zhengwei Mao Gaoxing Luo Jun Deng 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第12期357-357,共1页
Following publication of the original article[1],the authors reported an error in the last author’s name,it was mistakenly written as“Jun Den”.The correct author’s name“Jun Deng”has been updated in this Correction.
关键词 MISTAKE correct correction
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The application of the strip-shaped cymba conchae orthosis in the nonsurgical correction of complex auricular deformity 被引量:1
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作者 Huijuan Xu Shaoguang Ding +6 位作者 Fei Zhang Zhifeng Zhang Xiangyu Chen Mingyang Li Haitao Yang Fugen Han Hongjian Liu 《Journal of Otology》 CAS CSCD 2024年第1期24-29,共6页
Objective: This study aims to evaluate the efficacy and safety of using a strip-shaped cymba conchae orthosis for the nonsurgical correction of complex auricular deformities. Methods: Clinical data were collected from... Objective: This study aims to evaluate the efficacy and safety of using a strip-shaped cymba conchae orthosis for the nonsurgical correction of complex auricular deformities. Methods: Clinical data were collected from 2020 to 2021 for 6 patients who underwent correction using a stripshaped cymba conchae orthosis. The indications, corrective effects, and complications associated with use of the orthosis were analyzed. Results: There were four indications for treatment: cryptotia with helix adhesion;cryptotia with grade I microtia;cryptotia with excessive helix thickness;and auricular deformity beyond the treatment time window(≥6 months). Excellent corrective effects were observed in all 6 patients. Complications occurred in one patient, who recovered after symptomatic treatment. Conclusion: The use of a strip-shaped cymba conchae orthosis alone or combined with a U-shaped helix orthosis presents a feasible approach for correcting complex auricular deformities or deformities beyond the treatment time window in pediatric patients. 展开更多
关键词 Cymba conchae Auricular deformity Cryptotia Nonsurgical correction ORTHOSIS
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Adaptation analysis and fusion correction method of CMIP6 precipitation simulation data on the Qinghai-Tibetan Plateau
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作者 PENG Hao QIN Dahui +3 位作者 WANG Zegen ZHANG Menghan YANG Yanmei YONG Zhiwei 《Journal of Mountain Science》 SCIE CSCD 2024年第2期555-573,共19页
In order to obtain more accurate precipitation data and better simulate the precipitation on the Tibetan Plateau,the simulation capability of 14 Coupled Model Intercomparison Project Phase 6(CMIP6)models of historical... In order to obtain more accurate precipitation data and better simulate the precipitation on the Tibetan Plateau,the simulation capability of 14 Coupled Model Intercomparison Project Phase 6(CMIP6)models of historical precipitation(1982-2014)on the Qinghai-Tibetan Plateau was evaluated in this study.Results indicate that all models exhibit an overestimation of precipitation through the analysis of the Taylor index,temporal and spatial statistical parameters.To correct the overestimation,a fusion correction method combining the Backpropagation Neural Network Correction(BP)and Quantum Mapping(QM)correction,named BQ method,was proposed.With this method,the historical precipitation of each model was corrected in space and time,respectively.The correction results were then analyzed in time,space,and analysis of variance(ANOVA)with those corrected by the BP and QM methods,respectively.Finally,the fusion correction method results for each model were compared with the Climatic Research Unit(CRU)data for significance analysis to obtain the trends of precipitation increase and decrease for each model.The results show that the IPSL-CM6A-LR model is relatively good in simulating historical precipitation on the Qinghai-Tibetan Plateau(R=0.7,RSME=0.15)among the uncorrected data.In terms of time,the total precipitation corrected by the fusion method has the same interannual trend and the closest precipitation values to the CRU data;In terms of space,the annual average precipitation corrected by the fusion method has the smallest difference with the CRU data,and the total historical annual average precipitation is not significantly different from the CRU data,which is better than BP and QM.Therefore,the correction effect of the fusion method on the historical precipitation of each model is better than that of the QM and BP methods.The precipitation in the central and northeastern parts of the plateau shows a significant increasing trend.The correlation coefficients between monthly precipitation and site-detected precipitation for all models after BQ correction exceed 0.8. 展开更多
关键词 GCM CMIP6 Precipitation correction BP-QM fusion correction Spatio-temporal characteristics
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Correction: Surface Patterning of Metal ZincElectrode with an In-Region Zincophilic Interfacefor High-Rate and Long-Cycle-Life Zinc MetalAnode
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作者 Tian Wang Qiao Xi +8 位作者 Kai Yao Yuhang Liu Hao Fu Venkata Siva Kavarthapu Jun Kyu Lee Shaocong Tang Dina Fattakhova-Rohlfing Wei Ai Jae Su Yu 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第7期456-457,共2页
Correction to:Nano-Micro Letters(2024)16:112 https://doi.org/10.1007/s40820-024-01327-2 In the supplementary information the following corrections have been carried out:1.Institute of Energy and Climate Research,Mater... Correction to:Nano-Micro Letters(2024)16:112 https://doi.org/10.1007/s40820-024-01327-2 In the supplementary information the following corrections have been carried out:1.Institute of Energy and Climate Research,Materials Synthesis and Processing,Forschungszentrum Jülich GmbH,52425 Jülich,Germany.Corrected:Institute of Energy and Climate Research:Materials Synthesis and Processing(IEK-1),Forschungszentrum Jülich GmbH,52425 Jülich,Germany. 展开更多
关键词 correction ZINC ELECTRODE
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Author Correction:Recent Progress in Interfacial Dipole Engineering for Perovskite Solar Cells
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作者 Yinyi Ma Jue Gong +1 位作者 Peng Zeng Mingzhen Liu 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第9期500-500,共1页
In the version of this Article originally published online,there was an error in the schematics of Figures 2b and 2c.These errors have now been corrected in the original article.
关键词 corrected ERROR Solar
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Author Correction to “Enhanced Property of Thin Cuprous Oxide Film Prepared through Green Synthetic Route”
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作者 Achraf El Kasmi Henning Vieker +3 位作者 Ling-nan Wu AndréBeyer Tarik Chafik Zhenyu Tian 《Chinese Journal of Chemical Physics》 SCIE EI CAS CSCD 2024年第4期571-571,共1页
This correction adds some information to our publication[Chin.J.Chem.Phys.32,365–372(2019)]that we previously missed to include.Our previous work published in[Appl.Catal.B Env-iron.186,10(2016)]was based on the same ... This correction adds some information to our publication[Chin.J.Chem.Phys.32,365–372(2019)]that we previously missed to include.Our previous work published in[Appl.Catal.B Env-iron.186,10(2016)]was based on the same sample series but with the focus of explaining the interplay between the catalytic behavior and properties of the cuprous thin films.A superior catalytic performance was demonstrated when water was added in the deposition process[1](see Ref.[47]in our publication corrected here). 展开更多
关键词 films. CATALYTIC correction
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Correction to:Error Calculation of Large-Amplitude Internal Solitary Waves Within the Pycnocline Introduced by the Strong Stratification Approximation
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作者 Cunguo Xu Zhan Wang Masoud Hayatdavoodi 《哈尔滨工程大学学报(英文版)》 CSCD 2024年第1期247-247,共1页
In the original publication the third author name is published incorrectly as“Hayatdavoodi Masoud”.The correct author name should be read as“Masoud Hayatdavoodi”.The correct author name is available in this correc... In the original publication the third author name is published incorrectly as“Hayatdavoodi Masoud”.The correct author name should be read as“Masoud Hayatdavoodi”.The correct author name is available in this correction. 展开更多
关键词 STRONG Internal correction
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Correction: MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1
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作者 HUI SUN MASANORI KAWANO +4 位作者 TATSUYA IWASAKI ICHIRO ITONAGA YUTA KUBOTA HIROSHI TSUMURA KAZUHIRO TANAKA 《Oncology Research》 SCIE 2024年第8期1369-1370,共2页
In the article‘MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1’(Oncology Research,2024,Vol.32,No.3,pp.463−476.doi:10.32604/or.20... In the article‘MicroRNA-329-3p inhibits the Wnt/β-catenin pathway and proliferation of osteosarcoma cells by targeting transcription factor 7-like 1’(Oncology Research,2024,Vol.32,No.3,pp.463−476.doi:10.32604/or.2023.044085),there was an error in the compilation of Fig.8D.We have revised Fig.8D to correct this error.A corrected version of Fig.8 is provided.This correction does not change any results or conclusions of the article.We apologize for any inconvenience caused. 展开更多
关键词 OSTEOSARCOMA correction revised
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Real-time model correction using Kalman filter for Raman-controlled cell culture processes
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作者 Xiaoxiao Dong Zhuohong He +5 位作者 Xu Yan Dong Gao Jingyu Jiao Yan Sun Haibin Wang Haibin Qu 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第6期251-260,共10页
Raman spectroscopy has found extensive use in monitoring and controlling cell culture processes.In this context,the prediction accuracy of Raman-based models is of paramount importance.However,models established with ... Raman spectroscopy has found extensive use in monitoring and controlling cell culture processes.In this context,the prediction accuracy of Raman-based models is of paramount importance.However,models established with data from manually fed-batch cultures often exhibit poor performance in Raman-controlled cultures.Thus,there is a need for effective methods to rectify these models.The objective of this paper is to investigate the efficacy of Kalman filter(KF)algorithm in correcting Raman-based models during cell culture.Initially,partial least squares(PLS)models for different components were constructed using data from manually fed-batch cultures,and the predictive performance of these models was compared.Subsequently,various correction methods including the PLS-KF-KF method proposed in this study were employed to refine the PLS models.Finally,a case study involving the auto-control of glucose concentration demonstrated the application of optimal model correction method.The results indicated that the original PLS models exhibited differential performance between manually fed-batch cultures and Raman-controlled cultures.For glucose,the root mean square error of prediction(RMSEP)of manually fed-batch culture and Raman-controlled culture was 0.23 and 0.40 g·L^(-1).With the implementation of model correction methods,there was a significant improvement in model performance within Raman-controlled cultures.The RMSEP for glucose from updating-PLS,KF-PLS,and PLS-KF-KF was 0.38,0.36 and 0.17 g·L^(-1),respectively.Notably,the proposed PLS-KF-KF model correction method was found to be more effective and stable,playing a vital role in the automated nutrient feeding of cell cultures. 展开更多
关键词 Raman spectroscopy Model correction Algorithm Model-predictive control BIOPROCESS
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Iterative Subregion Correction Preconditioners with Adaptive Tolerance for Problems with Geometrically Localized Stiffness
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作者 Michael Franco Per-Olof Persson Will Pazner 《Communications on Applied Mathematics and Computation》 EI 2024年第2期811-836,共26页
We present a class of preconditioners for the linear systems resulting from a finite element or discontinuous Galerkin discretizations of advection-dominated problems.These preconditioners are designed to treat the ca... We present a class of preconditioners for the linear systems resulting from a finite element or discontinuous Galerkin discretizations of advection-dominated problems.These preconditioners are designed to treat the case of geometrically localized stiffness,where the convergence rates of iterative methods are degraded in a localized subregion of the mesh.Slower convergence may be caused by a number of factors,including the mesh size,anisotropy,highly variable coefficients,and more challenging physics.The approach taken in this work is to correct well-known preconditioners such as the block Jacobi and the block incomplete LU(ILU)with an adaptive inner subregion iteration.The goal of these preconditioners is to reduce the number of costly global iterations by accelerating the convergence in the stiff region by iterating on the less expensive reduced problem.The tolerance for the inner iteration is adaptively chosen to minimize subregion-local work while guaranteeing global convergence rates.We present analysis showing that the convergence of these preconditioners,even when combined with an adaptively selected tolerance,is independent of discretization parameters(e.g.,the mesh size and diffusion coefficient)in the subregion.We demonstrate significant performance improvements over black-box preconditioners when applied to several model convection-diffusion problems.Finally,we present performance results of several variations of iterative subregion correction preconditioners applied to the Reynolds number 2.25×10^(6)fluid flow over the NACA 0012 airfoil,as well as massively separated flow at 30°angle of attack. 展开更多
关键词 Subregion correction Nested Krylov Geometrically localized stiffness
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Thermodynamics in a quantum corrected Reissner-Nordstr?m-AdS black hole and its GUP-corrections
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作者 宋建君 刘成周 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第4期345-353,共9页
We calculate the thermodynamic quantities in the quantum corrected Reissner-Nordstr?m-AdS(RN-AdS)black hole,and examine their quantum corrections.By analyzing the mass and heat capacity,we give the critical state and ... We calculate the thermodynamic quantities in the quantum corrected Reissner-Nordstr?m-AdS(RN-AdS)black hole,and examine their quantum corrections.By analyzing the mass and heat capacity,we give the critical state and the remnant state,respectively,and discuss their consistency.Then,we investigate the quantum tunneling from the event horizon of massless scalar particle by using the null geodesic method,and charged massive boson W^(±)and fermions by using the Hamilton-Jacob method.It is shown that the same Hawking temperature can be obtained from these tunneling processes of different particles and methods.Next,by using the generalized uncertainty principle(GUP),we study the quantum corrections to the tunneling and the temperature.Then the logarithmic correction to the black hole entropy is obtained. 展开更多
关键词 black hole thermodynamics quantum corrections quantum tunneling generalized uncertainty principle
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Methodology for local correction of the heights of global geoid models to improve the accuracy of GNSS leveling
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作者 Stepan Savchuk Alina Fedorchuk 《Geodesy and Geodynamics》 EI CSCD 2024年第1期42-49,共8页
At present,one of the methods used to determine the height of points on the Earth’s surface is Global Navigation Satellite System(GNSS)leveling.It is possible to determine the orthometric or normal height by this met... At present,one of the methods used to determine the height of points on the Earth’s surface is Global Navigation Satellite System(GNSS)leveling.It is possible to determine the orthometric or normal height by this method only if there is a geoid or quasi-geoid height model available.This paper proposes the methodology for local correction of the heights of high-order global geoid models such as EGM08,EIGEN-6C4,GECO,and XGM2019e_2159.This methodology was tested in different areas of the research field,covering various relief forms.The dependence of the change in corrected height accuracy on the input data was analyzed,and the correction was also conducted for model heights in three tidal systems:"tide free","mean tide",and"zero tide".The results show that the heights of EIGEN-6C4 model can be corrected with an accuracy of up to 1 cm for flat and foothill terrains with the dimensionality of 1°×1°,2°×2°,and 3°×3°.The EGM08 model presents an almost identical result.The EIGEN-6C4 model is best suited for mountainous relief and provides an accuracy of 1.5 cm on the 1°×1°area.The height correction accuracy of GECO and XGM2019e_2159 models is slightly poor,which has fuzziness in terms of numerical fluctuation. 展开更多
关键词 GNSS leveling Global geoid model Gravity anomaly Weight data correcting data
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Automatic Miscalibration Detection and Correction of LiDAR and Camera Using Motion Cues
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作者 Pai Peng Dawei Pi +3 位作者 Guodong Yin Yan Wang Liwei Xu Jiwei Feng 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第2期318-329,共12页
This paper aims to develop an automatic miscalibration detection and correction framework to maintain accurate calibration of LiDAR and camera for autonomous vehicle after the sensor drift.First,a monitoring algorithm... This paper aims to develop an automatic miscalibration detection and correction framework to maintain accurate calibration of LiDAR and camera for autonomous vehicle after the sensor drift.First,a monitoring algorithm that can continuously detect the miscalibration in each frame is designed,leveraging the rotational motion each individual sensor observes.Then,as sensor drift occurs,the projection constraints between visual feature points and LiDAR 3-D points are used to compute the scaled camera motion,which is further utilized to align the drifted LiDAR scan with the camera image.Finally,the proposed method is sufficiently compared with two representative approaches in the online experiments with varying levels of random drift,then the method is further extended to the offline calibration experiment and is demonstrated by a comparison with two existing benchmark methods. 展开更多
关键词 Autonomous vehicle LiDAR and camera Miscalibration detection and correction Sensor drift
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Balancing act:The dilemma of rapid hyperglycemia correction in diabetes management
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作者 Ke-Xin Zhang Cheng-Xia Kan Xiao-Dong Sun 《World Journal of Diabetes》 SCIE 2024年第2期129-132,共4页
The global diabetes surge poses a critical public health challenge,emphasizing the need for effective glycemic control.However,rapid correction of chronic hyperglycemia can unexpectedly trigger microvascular complicat... The global diabetes surge poses a critical public health challenge,emphasizing the need for effective glycemic control.However,rapid correction of chronic hyperglycemia can unexpectedly trigger microvascular complications,necessitating a reevaluation of the speed and intensity of glycemic correction.Theories suggest swift blood sugar reductions may cause inflammation,oxidative stress,and neurovascular changes,resulting in complications.Healthcare providers should cautiously approach aggressive glycemic control,especially in long-standing,poorly controlled diabetes.Preventing and managing these complications requires a personalized,comprehensive approach with education,monitoring,and interdisciplinary care.Diabetes management must balance short and longterm goals,prioritizing overall well-being.This editorial underscores the need for a personalized,nuanced approach,focusing on equilibrium between glycemic control and avoiding overcorrection. 展开更多
关键词 DIABETES Hyperglycemia correction Management Microvascular complications Glucose control
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Chord length sampling correction analysis for dispersion fuel in Monte Carlo simulation
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作者 Zhao-Yu Liang Ding She +1 位作者 Yu-Tong Wen Lei Shi 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第4期57-64,共8页
Dispersion fuels,knowned for their excellent safety performance,are widely used in advanced reactors,such as hightemperature gas-cooled reactors.Compared with deterministic methods,the Monte Carlo method has more adva... Dispersion fuels,knowned for their excellent safety performance,are widely used in advanced reactors,such as hightemperature gas-cooled reactors.Compared with deterministic methods,the Monte Carlo method has more advantages in the geometric modeling of stochastic media.The explicit modeling method has high computational accuracy and high computational cost.The chord length sampling(CLS)method can improve computational efficiency by sampling the chord length during neutron transport using the matrix chord length?s probability density function.This study shows that the excluded-volume effect in realistic stochastic media can introduce certain deviations into the CLS.A chord length correction approach is proposed to obtain the chord length correction factor by developing the Particle code based on equivalent transmission probability.Through numerical analysis against reference solutions from explicit modeling in the RMC code,it was demonstrated that CLS with the proposed correction method provides good accuracy for addressing the excludedvolume effect in realistic infinite stochastic media. 展开更多
关键词 Stochastic media Monte Carlo Chord length sampling Excluded-volume effect Chord length correction
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Correction to“Research progress of ferroptosis regulating lipid peroxidation and metabolism in occurrence of primary liver cancer”
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作者 Yu-Jie Shu Bo Lao Ying-Yang Qiu 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第10期4298-4299,共2页
Correction to“Research progress of ferroptosis regulating lipid peroxidation and metabolism in occurrence and development of primary liver cancer”in World J Gastrointest Oncol 2024;16:2335-2349,published by Shu YJ,L... Correction to“Research progress of ferroptosis regulating lipid peroxidation and metabolism in occurrence and development of primary liver cancer”in World J Gastrointest Oncol 2024;16:2335-2349,published by Shu YJ,Lao B,and Qiu YY.In this article,we added the correct citations of images. 展开更多
关键词 correction Ferroptosis Lipid peroxidation Primary liver cancer Lipid metabolism
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Delta Compression Correction Method for Covert Communication in IoT
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作者 Hu Zhijuan Liu Shuangyu +2 位作者 Xu Fei Liu Liqiang Li Guiping 《China Communications》 SCIE CSCD 2024年第9期60-74,共15页
Covert communication can conceal the existence of wireless transmission and thus has the ability to address information security transfer issue in many applications of the booming Internet of Things(IoT).However,the p... Covert communication can conceal the existence of wireless transmission and thus has the ability to address information security transfer issue in many applications of the booming Internet of Things(IoT).However,the proliferation of sensing devices has generated massive amounts of data,which has increased the burden of covert communication.Considering the spatiotemporal correlation of data collection causing redundancy between data,eliminating duplicate data before transmission is beneficial for shortening transmission time,reducing the average received signal power of warden,and ultimately realizing covert communication.In this paper,we propose to apply delta compression technology in the gateway to reduce the amount of data generated by IoT devices,and then sent it to the cloud server.To this end,a cost model and evaluation method that is closer to the actual storage mode of computer systems is been constructed.Based on which,the delta version sequence obtained by existing delta compression algorithms is no longer compact,manifested by the still high cost.In this situation,we designed the correction scheme based on instructions merging(CSIM)correction to save costs by merging instructions.Firstly,the delta version sequence is divided into five categories and corresponding merge rules were derived.Then,for any COPY/ADD class delta compression algorithm,merge according to strict to relaxed to selection rules while generating instructions.Finally,a more cost-effective delta version sequence can be gained.The experimental results on random data show that the delta version sequences output by the CSIM corrected 1.5-pass and greedy algorithms have better performance in cost reducing. 展开更多
关键词 correction method covert communica-tion delta compression Internet of Things(IoT)
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Single Photon Detection Technology in Underwater Wireless Optical Communication:Modulation Modes and Error Correction Coding Analysis
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作者 GAI Lei LI Wendong WANG Guoyu 《Journal of Ocean University of China》 CAS CSCD 2024年第2期405-414,共10页
This study explores the application of single photon detection(SPD)technology in underwater wireless optical communication(UWOC)and analyzes the influence of different modulation modes and error correction coding type... This study explores the application of single photon detection(SPD)technology in underwater wireless optical communication(UWOC)and analyzes the influence of different modulation modes and error correction coding types on communication performance.The study investigates the impact of on-off keying(OOK)and 2-pulse-position modulation(2-PPM)on the bit error rate(BER)in single-channel intensity and polarization multiplexing.Furthermore,it compares the error correction performance of low-density parity check(LDPC)and Reed-Solomon(RS)codes across different error correction coding types.The effects of unscattered photon ratio and depolarization ratio on BER are also verified.Finally,a UWOC system based on SPD is constructed,achieving 14.58 Mbps with polarization OOK multiplexing modulation and 4.37 Mbps with polarization 2-PPM multiplexing modulation using LDPC code error correction. 展开更多
关键词 error correction coding modulation mode single photon detection underwater communication wireless optical communication
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Atmospheric transmission algorithm for pulsed X-rays from high-altitude nuclear detonations based on scattering correction
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作者 Ding-Han Zhu Xiong Zhang +3 位作者 Xiao-Qiang Li Peng Li Yan-Bin Wang Shuang Zhang 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第3期40-52,共13页
In high-altitude nuclear detonations,the proportion of pulsed X-ray energy can exceed 70%,making it a specific monitoring signal for such events.These pulsed X-rays can be captured using a satellite-borne X-ray detect... In high-altitude nuclear detonations,the proportion of pulsed X-ray energy can exceed 70%,making it a specific monitoring signal for such events.These pulsed X-rays can be captured using a satellite-borne X-ray detector following atmospheric transmission.To quantitatively analyze the effects of different satellite detection altitudes,burst heights,and transmission angles on the physical processes of X-ray transport and energy fluence,we developed an atmospheric transmission algorithm for pulsed X-rays from high-altitude nuclear detonations based on scattering correction.The proposed method is an improvement over the traditional analytical method that only computes direct-transmission X-rays.The traditional analytical method exhibits a maximum relative error of 67.79% compared with the Monte Carlo method.Our improved method reduces this error to within 10% under the same conditions,even reaching 1% in certain scenarios.Moreover,its computation time is 48,000 times faster than that of the Monte Carlo method.These results have important theoretical significance and engineering application value for designing satellite-borne nuclear detonation pulsed X-ray detectors,inverting nuclear detonation source terms,and assessing ionospheric effects. 展开更多
关键词 High-altitude nuclear detonation Atmospheric transmission Pulsed X-rays Scattering correction Analytical method Monte Carlo method
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Stimulated Raman scattering microscopy with phase-controlled light focusing and aberration correction for rapid and label-free, volumetric deep tissue imaging
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作者 Weiqi Wang Zhiwei Huang 《Opto-Electronic Advances》 SCIE EI CAS CSCD 2024年第9期40-52,共13页
We report a novel stimulated Raman scattering(SRS)microscopy technique featuring phase-controlled light focusing and aberration corrections for rapid,deep tissue 3D chemical imaging with subcellular resolution.To acco... We report a novel stimulated Raman scattering(SRS)microscopy technique featuring phase-controlled light focusing and aberration corrections for rapid,deep tissue 3D chemical imaging with subcellular resolution.To accomplish phasecontrolled SRS(PC-SRS),we utilize a single spatial light modulator to electronically tune the axial positioning of both the shortened-length Bessel pump and the focused Gaussian Stokes beams,enabling z-scanning-free optical sectioning in the sample.By incorporating Zernike polynomials into the phase patterns,we simultaneously correct the system aberrations at two separate wavelengths(~240 nm difference),achieving a~3-fold enhancement in signal-to-noise ratio over the uncorrected imaging system.PC-SRS provides>2-fold improvement in imaging depth in various samples(e.g.,polystyrene bead phantoms,porcine brain tissue)as well as achieves SRS 3D imaging speed of~13 Hz per volume for real-time monitoring of Brownian motion of polymer beads in water,superior to conventional point-scanning SRS 3D imaging.We further utilize PC-SRS to observe the metabolic activities of the entire tumor liver in living zebrafish in cellsilent region,unraveling the upregulated metabolism in liver tumor compared to normal liver.This work shows that PCSRS provides unprecedented insights into morpho-chemistry,metabolic and dynamic functioning of live cells and tissue in real-time at the subcellular level. 展开更多
关键词 SRS 3D imaging phase-controlled light focusing image aberration corrections deep tissue imaging
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