In this paper, we study the anti-periodic solutions for 2n-th order differential equations. By using the Schauder＇s fixed point theorem, we present some new results about the existence and uniqueness of anti-periodic...In this paper, we study the anti-periodic solutions for 2n-th order differential equations. By using the Schauder＇s fixed point theorem, we present some new results about the existence and uniqueness of anti-periodic solutions for 2n-th order differential equations.展开更多
In this work, we introduce a few versions of Caristi’s fixed point theorems in G-cone metric spaces which extend Caristi’s fixed point theorems in metric spaces. Analogues of such fixed point theorems are proved in ...In this work, we introduce a few versions of Caristi’s fixed point theorems in G-cone metric spaces which extend Caristi’s fixed point theorems in metric spaces. Analogues of such fixed point theorems are proved in this space. Our work extends a good number of results in this area of research.展开更多
Objective To observe the clinical effect of blood-letting puncture and cupping at Chōngxiāo（冲霄 Extra） point of Dong＇s unique Extra-ordinary points in the treatment of neck type of cervical spondylosis.Methods S...Objective To observe the clinical effect of blood-letting puncture and cupping at Chōngxiāo（冲霄 Extra） point of Dong＇s unique Extra-ordinary points in the treatment of neck type of cervical spondylosis.Methods Sixty-five patients of neck type of cervical spondylosis were selected and treated with blood-letting puncture and cupping at Chōngxiāo（冲霄 Extra） point once every two or three days,three times constituted one course and two successive courses were given,then the clinical effect was evaluated.Results The curative rate was 69.2%（45/65）,and the total effective rate was 92.3%（60/65）.Conclusion Blood-letting puncture and cupping at Dong＇s Chōngxiāo（冲霄 Extra） point can be used to treat neck type of cervical spondylosis with simple manipulation and obvious efficacy.展开更多
目的:观察针刺董氏奇穴联合内服中药治疗混合性焦虑抑郁障碍(Mixed Anxiety and Depressive Disorder,MADD)痰气郁结证的疗效。方法:选择2020年4月至2021年10月江海区中西医结合医院治疗的MADD患者90例,随机分为对照组、观察A组、观察B...目的:观察针刺董氏奇穴联合内服中药治疗混合性焦虑抑郁障碍(Mixed Anxiety and Depressive Disorder,MADD)痰气郁结证的疗效。方法:选择2020年4月至2021年10月江海区中西医结合医院治疗的MADD患者90例,随机分为对照组、观察A组、观察B组各30例。对照组予口服氟哌噻吨美利曲辛片,观察A组予内服温胆汤合丹栀逍遥散加减,观察B组在观察A组治疗的基础上予针刺董氏奇穴,均治疗12周,治疗后对比三组患者的医院焦虑抑郁量表(Hospital Anxiety and Depression Scale,HADS)评分、中医证候评分、临床疗效及不良反应。结果:治疗前,三组患者的HADS评分、痰气郁结证评分对比,差异无统计学意义(P>0.05);治疗后,三组患者的HADS评分、痰气郁结证评分均较治疗前下降(P<0.05),其中观察A组、观察B组的HADS评分、痰气郁结证评分均明显低于对照组(P<0.05),观察B组的HADS评分、痰气郁结证评分均明显低于观察A组(P<0.05)。观察B组的总有效率(93.33%)高于观察A组(86.67%)、对照组(73.33%)(P<0.05)。治疗期间,对照组不良反应发生率为13.33%,观察A组为6.67%,观察B组为10.00%,差异无统计学意义(P>0.05)。结论:针刺董氏奇穴联合内服中药具有行气开郁、化痰散结、清肝泻火之功效,治疗MADD痰气郁结证安全有效,值得在临床中推广应用。展开更多
目的:通过环芳香烃受体(cyclic aromatic hydrocarbon receptor,AhR)/白细胞介素22(interleukin-22,IL-22)/信号转导和转录激活因子3(signal transducer and activator of transcription3,STAT3)通路探讨董氏奇穴联合丁沉扶正汤对胃癌...目的:通过环芳香烃受体(cyclic aromatic hydrocarbon receptor,AhR)/白细胞介素22(interleukin-22,IL-22)/信号转导和转录激活因子3(signal transducer and activator of transcription3,STAT3)通路探讨董氏奇穴联合丁沉扶正汤对胃癌患者术后肠道菌群紊乱的影响,并探讨其具体作用机制。方法:选择接受腹腔镜下胃癌根治术的患者120例,随机分为对照组和针药联合组,每组60例。对照组接受董氏奇穴针灸治疗,针药联合组在对照组的基础上给予丁沉扶正汤治疗。比较两组术中指标、T淋巴细胞亚群、D-乳酸(D-Lactic acid,D-LA)、炎性因子、肠道细菌以及肠黏膜组织AhR/IL-22/STAT3通路转录和翻译水平。结果:两组干预前指标比较,差异无统计学意义(P>0.05)。干预后两组乳酸杆菌、双歧杆菌含量、CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)比值均升高(P<0.05),且上述指标针药联合组均高于对照组(P<0.05)。干预后两组肠道中大肠杆菌、梭菌、拟杆菌、柔嫩梭菌水平及血清中D-乳酸、降钙素原、C反应蛋白(C-reactive protein,CRP)和白细胞介素-6(interleukin-6,IL-6)水平均降低(P<0.05),且以上指标针药联合组均显著低于对照组(P<0.05)。针药联合组住院时间显著短于对照组(P<0.05)。与干预前比较,两组AhR、IL-22和STAT3 mRNA及蛋白水平均升高(P<0.05),针药联合组高于对照组(P<0.05)。结论:董氏奇穴联合丁沉扶正汤可能通过促进AhR/IL-22/STAT3通路保护肠黏膜屏障,进而改善胃癌患者术后的细胞免疫功能、缓解肠道菌群失衡,促进患者恢复。展开更多
Objective:To investigate the clinical effect of electroacupuncture combined with biofeedback on functional anorectal pain.Methods:Sixty patients diagnosed functional anorectal pain were divided into three groups by ra...Objective:To investigate the clinical effect of electroacupuncture combined with biofeedback on functional anorectal pain.Methods:Sixty patients diagnosed functional anorectal pain were divided into three groups by random number table,namely electroacupuncture group,biofeedback group,and combination group,with 20 patients in each.In the electroacupuncture group,the electroacupuncture at Dong’s points Sānqí(三其穴),including Qímén(其门),Qíjiǎo(其角),and Qízhéng(其正),and Línggǔ(灵骨),Dàbái(大白),Chángmén(肠门)of both sides was given;in the Biofeedback group,the biofeedback therapy was adopted;in the combination group,the electroacupuncture and biofeedback therapy were used.All patients were treated once a day,30 min each time,10 consecutive treatments as one treatment course,and the therapeutic effect was evaluated after 3 treatment courses.The observation indexes after the intervention:Visual analogue Scale(VAS)score,SF-36 Quality of Life Scale score,Self-rating Anxiety Scale(SAS)score,Self-rating Depression Scale(SDS)score,Anorectal manometry,Clinical efficacy,and patients’adverse reactions.Results:After treatment,the pain of patients in the three groups was alleviated than that before treatment,VAS score,SAS score,SDS score,and anorectal pressure were decreased(P<0.05),and SF-36 Quality of Life Scale score was increased(P<0.05).After treatment,in the combination group,the VAS scores,SAS scores,SDS scores,and Anal-rectal pressure scores were lower than those in the other two groups(P<0.05),and SF-36 Quality of Life Scale scores were higher than those in the other two groups(P<0.05),the total effective rate was 80.0%(16/20),which was significantly higher than that of the electroacupuncture group(55.0%,11/20)and the biofeedback group(40.0%,8/20)(both P<0.05).No adverse reactions occurred in all three groups.Conclusion:Electroacupuncture at Dong’s points combined with biofeedback therapy has a significant effect on functional anorectal pain.The combined application of electroacupuncture and biofeedback therapy has a synergic action,and the analgesic effect is better than that of only using electroacupuncture or biofeedback therapy.展开更多
目的观察双e疗法刺激董氏奇穴治疗2型糖尿病患者口服降糖药继发性失效的临床疗效及安全性。方法将120例口服降糖药继发性失效的2型糖尿病患者随机分为治疗组和对照组,每组60例,在口服基础降糖药的基础上,治疗组给予针挑结合放血刺激董...目的观察双e疗法刺激董氏奇穴治疗2型糖尿病患者口服降糖药继发性失效的临床疗效及安全性。方法将120例口服降糖药继发性失效的2型糖尿病患者随机分为治疗组和对照组,每组60例,在口服基础降糖药的基础上,治疗组给予针挑结合放血刺激董氏奇穴,对照组给予二甲双胍,并进行疗效评价。结果治疗后,两组患者的空腹血糖值(FPG)、2 h血糖值(2 h PG)、糖化血红蛋白(Hb A1c)等指标较治疗前都有明显下降(P<0.05),组间比较治疗组优于对照组(P<0.05);治疗后治疗组总有效率93.33%明显优于对照组85%(P<0.05)。结论双e疗法刺激董氏奇穴与二甲双胍对继发性磺脲类降糖药失效的2型糖尿病患者均有效,可以改善胰岛素抵抗,此外"双e疗法"的副作用小,绿色经济,有良好的临床推广前景。展开更多
文摘In this paper, we study the anti-periodic solutions for 2n-th order differential equations. By using the Schauder＇s fixed point theorem, we present some new results about the existence and uniqueness of anti-periodic solutions for 2n-th order differential equations.
文摘In this work, we introduce a few versions of Caristi’s fixed point theorems in G-cone metric spaces which extend Caristi’s fixed point theorems in metric spaces. Analogues of such fixed point theorems are proved in this space. Our work extends a good number of results in this area of research.
文摘Objective To observe the clinical effect of blood-letting puncture and cupping at Chōngxiāo（冲霄 Extra） point of Dong＇s unique Extra-ordinary points in the treatment of neck type of cervical spondylosis.Methods Sixty-five patients of neck type of cervical spondylosis were selected and treated with blood-letting puncture and cupping at Chōngxiāo（冲霄 Extra） point once every two or three days,three times constituted one course and two successive courses were given,then the clinical effect was evaluated.Results The curative rate was 69.2%（45/65）,and the total effective rate was 92.3%（60/65）.Conclusion Blood-letting puncture and cupping at Dong＇s Chōngxiāo（冲霄 Extra） point can be used to treat neck type of cervical spondylosis with simple manipulation and obvious efficacy.
文摘目的:观察针刺董氏奇穴联合内服中药治疗混合性焦虑抑郁障碍(Mixed Anxiety and Depressive Disorder,MADD)痰气郁结证的疗效。方法:选择2020年4月至2021年10月江海区中西医结合医院治疗的MADD患者90例,随机分为对照组、观察A组、观察B组各30例。对照组予口服氟哌噻吨美利曲辛片,观察A组予内服温胆汤合丹栀逍遥散加减,观察B组在观察A组治疗的基础上予针刺董氏奇穴,均治疗12周,治疗后对比三组患者的医院焦虑抑郁量表(Hospital Anxiety and Depression Scale,HADS)评分、中医证候评分、临床疗效及不良反应。结果:治疗前,三组患者的HADS评分、痰气郁结证评分对比,差异无统计学意义(P>0.05);治疗后,三组患者的HADS评分、痰气郁结证评分均较治疗前下降(P<0.05),其中观察A组、观察B组的HADS评分、痰气郁结证评分均明显低于对照组(P<0.05),观察B组的HADS评分、痰气郁结证评分均明显低于观察A组(P<0.05)。观察B组的总有效率(93.33%)高于观察A组(86.67%)、对照组(73.33%)(P<0.05)。治疗期间,对照组不良反应发生率为13.33%,观察A组为6.67%,观察B组为10.00%,差异无统计学意义(P>0.05)。结论:针刺董氏奇穴联合内服中药具有行气开郁、化痰散结、清肝泻火之功效,治疗MADD痰气郁结证安全有效,值得在临床中推广应用。
基金Supported by Innovation and Application Project,Chongqing Bureau of Science and Technology:cstc2019jscx-msxmX02292019"Xinglin Scholar"Project of Chongqing TCM Hospital affiliated to Chengdu University of Traditional Chinese Medicine:YYZX2019080Chongqing famous senior TCM expert Xu Yue inheritance studio。
文摘Objective:To investigate the clinical effect of electroacupuncture combined with biofeedback on functional anorectal pain.Methods:Sixty patients diagnosed functional anorectal pain were divided into three groups by random number table,namely electroacupuncture group,biofeedback group,and combination group,with 20 patients in each.In the electroacupuncture group,the electroacupuncture at Dong’s points Sānqí(三其穴),including Qímén(其门),Qíjiǎo(其角),and Qízhéng(其正),and Línggǔ(灵骨),Dàbái(大白),Chángmén(肠门)of both sides was given;in the Biofeedback group,the biofeedback therapy was adopted;in the combination group,the electroacupuncture and biofeedback therapy were used.All patients were treated once a day,30 min each time,10 consecutive treatments as one treatment course,and the therapeutic effect was evaluated after 3 treatment courses.The observation indexes after the intervention:Visual analogue Scale(VAS)score,SF-36 Quality of Life Scale score,Self-rating Anxiety Scale(SAS)score,Self-rating Depression Scale(SDS)score,Anorectal manometry,Clinical efficacy,and patients’adverse reactions.Results:After treatment,the pain of patients in the three groups was alleviated than that before treatment,VAS score,SAS score,SDS score,and anorectal pressure were decreased(P<0.05),and SF-36 Quality of Life Scale score was increased(P<0.05).After treatment,in the combination group,the VAS scores,SAS scores,SDS scores,and Anal-rectal pressure scores were lower than those in the other two groups(P<0.05),and SF-36 Quality of Life Scale scores were higher than those in the other two groups(P<0.05),the total effective rate was 80.0%(16/20),which was significantly higher than that of the electroacupuncture group(55.0%,11/20)and the biofeedback group(40.0%,8/20)(both P<0.05).No adverse reactions occurred in all three groups.Conclusion:Electroacupuncture at Dong’s points combined with biofeedback therapy has a significant effect on functional anorectal pain.The combined application of electroacupuncture and biofeedback therapy has a synergic action,and the analgesic effect is better than that of only using electroacupuncture or biofeedback therapy.
文摘目的观察双e疗法刺激董氏奇穴治疗2型糖尿病患者口服降糖药继发性失效的临床疗效及安全性。方法将120例口服降糖药继发性失效的2型糖尿病患者随机分为治疗组和对照组,每组60例,在口服基础降糖药的基础上,治疗组给予针挑结合放血刺激董氏奇穴,对照组给予二甲双胍,并进行疗效评价。结果治疗后,两组患者的空腹血糖值(FPG)、2 h血糖值(2 h PG)、糖化血红蛋白(Hb A1c)等指标较治疗前都有明显下降(P<0.05),组间比较治疗组优于对照组(P<0.05);治疗后治疗组总有效率93.33%明显优于对照组85%(P<0.05)。结论双e疗法刺激董氏奇穴与二甲双胍对继发性磺脲类降糖药失效的2型糖尿病患者均有效,可以改善胰岛素抵抗,此外"双e疗法"的副作用小,绿色经济,有良好的临床推广前景。
