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ASSESSMENT OF LEFT VENTRICULAR FUNCTION IN HEALTHY SUBJECTS BY PUSLED WAVE DOPPLER TISSUE IMAGING 被引量:4
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作者 李靖 刘延玲 +3 位作者 王浩 吕秀章 段福建 杨洪昌 《Chinese Medical Sciences Journal》 CAS CSCD 2004年第1期64-67,共4页
Objective To examine the clinical application of pulsed Doppler tissue imaging(DTI)for regional left ventricular function assessment in normal subjects. Methods We examined 50 healthy subjects(range 12-42 years,mean a... Objective To examine the clinical application of pulsed Doppler tissue imaging(DTI)for regional left ventricular function assessment in normal subjects. Methods We examined 50 healthy subjects(range 12-42 years,mean age 28.3 ± 6.9 years)using pulsed Doppler tissue imaging to characterize the diastolic and systolic velocity profiles of mitral annulus. Recordings were made along the long axis in the apical 4-chamber, 2-chamber, and long apical views of 6 sites(posterior-septum, lateral, anterior, inferior, anterior-septum, posterior)at the mitral annulus. Myocardial velocities were determined with use of variance F statistical analysis. Correlation analysis was employed to test the relationship between age and mitral annular velocities. Results Both early diastolic and systolic velocities at the septum were lower than other sites. There were no differences in mitral annulus late diastolic velocities. Mean early diastolic and systolic velocities was negatively correlated with age. Conclusions Doppler tissue imaging can directly reflect regional left ventricular function. 展开更多
关键词 doppler tissue imaging left ventricular function
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Left ventricular regional and global diastolic function assessed using Quantitative Tissue velocity Imaging in patients with hypertrophic cardiomyopathy
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作者 王良玉 王新房 +2 位作者 谢明星 蔡志雄 陈纪平 《South China Journal of Cardiology》 CAS 2003年第2期119-124,共6页
Objectives The study was performed to assess the left ventricular (LV) regional and global diastolic function、left ventricular wall motion features in patients with Hypertrophic cardiomyopathy by Quantitative Tissue ... Objectives The study was performed to assess the left ventricular (LV) regional and global diastolic function、left ventricular wall motion features in patients with Hypertrophic cardiomyopathy by Quantitative Tissue Velocity Imaging (QTVI). Methods 42 patients with hypertrophic cardiomyopathy and 36 age-matched normal subjects underwent QTVI study. Off-line LV regional muscular tissue velocity Imaging along LV apical long-axis view were obtained. Regional diastolic function was assessed in using peak tissue velocities of LV regional muscular tissue during early diastole (Ve)and LA contraction (Va), Ve/Va ratio, derived from Tissue Velocity Imaging. Global diastolic function was reflected by isovolumic relaxation time(IRT) and mitral valve peak flow velocity ( E/A ) calculated with pulsed wave doppler. The end-diastolic interventricular septal thickness (ⅣSt) was measured by conventional 2 - dimension echocardiography. Results ① Ve、 Va、 Ve/Va in the segments of hypertrophic interventricular septum (IVS) reduced wlhile E/A ratio significantly reduced and IRT markedly prolonged in HCM patients than in normal subjects。 ② Ve、 Ve/Va were significant reduced in the segments of hypertrophic interventricular septum compared with other LV segments in HCM patients . ③ There was a correlation between Ve/Va and E/A in HCM patients with abnormal E/A ratio (r = 0. 70). ④ There was a negative correlation between Ve/Va and ⅣSt in non -obstruction HCM patients (B group , r = -0.61 ) Conclusions QTVI offers a newer method in clinical practice which has a higher sensibility and accuracy in evaluating the LV regional and global diastolic function in HCM patients . 展开更多
关键词 Quantitative tissue velocity imaging Hypertrophy cardiomyopathy left ventricular diastolic function
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Left Ventricular Regional Systolic Function in Patient with Hypertrophic Cardiomyopathy by Quantitative Tissue Velocity Imaging 被引量:3
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作者 李秀兰 邓又斌 杨好意 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2006年第1期153-156,共4页
The left ventricular regional systolic functions in patients with hypertrophic cardiomyopathy (HCM) were assessed by using quantitative tissue velocity imaging (QTVI). Left ventricular (LV) regional myocardial v... The left ventricular regional systolic functions in patients with hypertrophic cardiomyopathy (HCM) were assessed by using quantitative tissue velocity imaging (QTVI). Left ventricular (LV) regional myocardial velocity along long- and short-axis in 31 HCM patients and 20 healthy subjects were analyzed by QTVI, and the regional myocardial systolic peak velocities (MVS) were measured. Mean MVS at each level including mitral annular, basal, middle and apical segments were calculated. The ratio of MVS along long-axis to that along short-axis (Ri) at basal and middle segments of the LV posterior wall and ventricular septum were calculated. The results showed that mean MVS was slower at each level including mitral annular, basal, middle and apical segments in the HCM patients than that in the healthy subjects (P〈0.01). There were no significant differences in mean MVS between obstructive and non-obstructive groups in HCM patients. MVS of all regional myocardial segments along long-axis in the HCM patients were significantly slower than that in the healthy subjects (P〈0.05), but there was no significant difference in MVS of all regional myocardial segments along long-axis between hypertrophied and non-hypertrophied group in the HCM patients. Ri was significantly lower in the HCM patients than that in the healthy subjects. The LV regional myocardial contractility along long-axis was impaired not only in the hypertrophied wall but also in the non-hypertrophied one in patients with HCM, suggesting that QTVI can assess accurately LV regional systolic function in patient with HCM and provides a novel means for an early diagnosis before and independent of hypertrophy. 展开更多
关键词 quantitative tissue velocity imaging hypertrophic cardiomyopathy left ventricular regional systolic function
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Evaluation of Normal Fetal Left Cardiac Function by Tissue Doppler Imaging 被引量:3
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作者 陆永萍 邓又斌 +3 位作者 刘娅妮 常青 杨好意 黎春蕾 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2006年第2期251-253,共3页
To explore the feasibility of using tissue Doppler imaging technique for the evaluation of fetus's left ventrieular diastolic function, and to confirm its reliability by comparing it with traditional methods, this st... To explore the feasibility of using tissue Doppler imaging technique for the evaluation of fetus's left ventrieular diastolic function, and to confirm its reliability by comparing it with traditional methods, this study examined 61 pregnant women in whom satisfactory images were obtained of fetal eehoeardiography. The peak velocity of blood stream were measured, including E, A and E/A at mitral valve orifice on the four chamber view with pulse wave. And then tissue Doppler imaging mode was employed to measure the velocity of mitral valve annulus including Ea, Aa, Sa and Ea / Aa. Correlation analysis was conducted between the velocity of orifice and that of annulus in terms of gestation age. And then correlation analysis was performed between above data and gestation ages. A positive correlation was found between the velocity of orifice and that of annulus, and the velocity increased with the gestation age. The change was the most significant between the 28th and the 34th week of gestation age. Our study showed that it is feasible to evaluate the fetus's left ven trieular diastole function by tissue Doppler imaging. Its stability can avoid the influence of fetal heart rates and preload. 展开更多
关键词 tissue doppler imaging fetal cardiac function
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Ultrasound Speckle Tracking Imaging Contributes to Early Diagnosis of Impaired Left Ventricular Systolic Function in Patients with Type 2 Diabetes Mellitus 被引量:11
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作者 马红 谢明星 +5 位作者 王静 吕清 王新房 卢晓芳 杨亚利 胡莉君 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2008年第6期719-723,共5页
To investigate the value of ultrasound speckle tracking imaging (STI) in the assessment of the short-axis and long-axis systolic function of the left ventricle (LV) in patients with type 2 diabetes mellitus (DM)... To investigate the value of ultrasound speckle tracking imaging (STI) in the assessment of the short-axis and long-axis systolic function of the left ventricle (LV) in patients with type 2 diabetes mellitus (DM), 100 subjects with normal ejection fraction were studied, including 41 patients with DM only (DM group), 22 patients with both DM and left ventricular hypertrophy (DH group), and 37 healthy subjects (control group). Left ventricle systolic function in the long axis defined as longitudinal strain, and that in the short axis defined as radial strain, apical and basal LV rotations, and LV twist were assessed respectively. The results showed that average peak strain in the long axis at basal, middle and apical levels, and global peak strain were significantly decreased in the patient groups when compared with the control group (P〈0.001 for each). The parameters in DH group were significantly lower than those in DM group (P〈0.01 for each). There were no significant differences in average radial peak strain in the short axis at different levels, and global peak strain among the three groups (P〉0.05). Apical and basal LV rotations, and LV twist were greater in the patient groups than in the control group (P〈0.01 for each). Basal LV rotation and LV twist were greater in DH group than those in DM group (P〈0.01). It was concluded that STI may be used to identify early abnormalities in patients with type 2 DM that have normal left ventricular systolic function. 展开更多
关键词 ECHOCARDIOGRAPHY diabetes mellitus ventricular function left speckle tracking imaging
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Experimental Study of Assessment on Ventricular Activation Origin and Contraction Sequence by Doppler Tissue Imaging 被引量:4
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作者 冀瑞平 王新房 +3 位作者 郑宗锷 刘望彭 李治安 刘俐 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2002年第1期52-57,共6页
To evaluate the possibility and accuracy of Doppler tissue image (DTI) on assessment of normal and abnormal ventricular activation and contraction sequence, 9 open chest canine hearts were analyzed by acceleration mod... To evaluate the possibility and accuracy of Doppler tissue image (DTI) on assessment of normal and abnormal ventricular activation and contraction sequence, 9 open chest canine hearts were analyzed by acceleration mode, M mode, and spectrum mode DTI. Our results showed that: (1) Acceleration mode DTI could show the origin of activation and conduction sequence on line; (2) M mode DTI revealed that the activation in mid interventricular septum was earlier than that in mid left ventricular posterior wall at sinus activation; (3) Spectrum DTI showed the ventricular endocardium was activated earlier than the ventricular epicardium in all segments at sinus rhythm. The earliest site of activation of the normal ventricular wall was at middle interventricular septum; the latest site was at basal posterior wall; the contraction sequence was different at the different walls; (4) During abnormal ventricular activation, mid left ventricular posterior wall was activated earliest in accordance with the pacing sites. Abnormal ventricular activation was slower than sinus activation, and the contraction sequence varied at different sites of ventricular wall. It is concluded that DTI can be used to localize the origin of normal or abnormal myocardial activation and to assess the contraction sequence conveniently, accurately and non invasively. 展开更多
关键词 doppler tissue imaging sinus activation abnormal ventricular activation contraction sequence
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ASSESSMENT OF DIASTOLIC FUNCTION IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY BY DOPPLER TISSUE IMAGING 被引量:2
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作者 JingLi Yan-lingLiu HaoWang Xiu-zhangLü Hong-changYang Fu-jianDuan Zhen-huiZhu 《Chinese Medical Sciences Journal》 CAS CSCD 2004年第3期203-206,共4页
To determine the clinical application of pulsed Doppler tissue imaging in assessing the left ventricular diasto-lic function and in discriminating between normal subjects and patients with hypertrophic cardiomyopathy ... To determine the clinical application of pulsed Doppler tissue imaging in assessing the left ventricular diasto-lic function and in discriminating between normal subjects and patients with hypertrophic cardiomyopathy with various stages of diastolic dysfunction. Methods We measured the peak diastolic velocities of mitral annulus in 81 patients with hypertrophic cardiomyopathy with various stages of diastolic dysfunction and 50 normal volunteers by Doppler tissue imaging using the apical window at 2-ch-amber and long apical views, respectively. The myocardial velocities were determined with use of variance F statistical analysis. Results Early diastolic myocardial velocities of mitral annulus were higher in normal subjects than in patients with hy-pertrophic cardiomyopathy with either delayed relaxation, pseudonormal filling, or restrictive filling. However, peak myocar-dial velocities of mitral annulus during atrial contraction were similar in normal subjects and patients with hypertrophic cardiomyopathy. Conclusion Doppler tissue imaging can directly reflect upon left diastolic ventricular function. Early phase of diastole was the best discriminator between control subjects and patients with hypertrophic cardiomyopathy. 展开更多
关键词 doppler tissue imaging left ventricular diastolic function hypertrophic cardiomyopathy
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In Vitro Validation of Tissue Doppler Left Ventricular Regional Wall Velocities by Using a Novel Balloon Phantom 被引量:1
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作者 吴瑛 李小魁 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2001年第4期337-340,共4页
To investigate the validity and accuracy of tissue Doppler imaging (TDI) using a novel balloon phantom, validation of TDI myocardial velocity measurements has been carried out indirectly from conventional M mode imag... To investigate the validity and accuracy of tissue Doppler imaging (TDI) using a novel balloon phantom, validation of TDI myocardial velocity measurements has been carried out indirectly from conventional M mode images. However it is not a true and independent gold standard. We described a new TDI validation method by using a specially developed left ventricular balloon model mounted in a water bath and constructed using two pear shaped balloons. It was connected to a pulsatile flow pump at 8 stroke volumes (50-85 ml/beat). The displacement and velocity of the balloon walls were recorded simultaneously by video imaging and TDI on a GE Vingmed System Five with a 5 MHz phased array probe at the highest frame rates available. Conventional M mode and 2 D imaging verified that our balloon model mimicked the shape and wall motion of left ventricle. There was a good correlation and agreement between the maximum video excursion of the anterior and posterior walls of the phantom and the results of the temporal integration of digital distance data by TDI (Anterior wall: r =0.97, SEE=0.24 mm, ±s =0.04±0.24 mm; Posterior wall: r =0.95, SEE=0.22 mm, ±s =0.03±0.24 mm). Analysis of the velocity profile by the TDI method showed that the velocity at each measured point was correlated well with the velocity obtained from the video images (Anterior wall: r =0.97, SEE=0.30 mm, ±s =-0.04±0.28 mm; Posterior wall: r =0.97, SEE=0.30 mm, ±s =0.04±0.28 mm). Our balloon model provided a new independent method for the validation of TDI data. This study demonstrated that the present TDI system is reliable for measuring wall motion distance and velocity. 展开更多
关键词 tissue doppler imaging in vitro left ventricular regional velocity
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Assessment of Left Ventricular Mechanical Function in Cardiac Syndrome X: Speckle Tracking Imaging Study
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作者 Mahmoud Kamel Ahmed Emara +1 位作者 Said Shalaby Montaser Mahmoud Said 《World Journal of Cardiovascular Diseases》 2018年第12期557-568,共12页
Objective: Early detection of LV mechanical abnormalities in patients with cardiac syndrome X (CSX) by speckle tracking echocardiography (STE). Background: Cardiac syndrome X is a triad of angina pectoris, positive st... Objective: Early detection of LV mechanical abnormalities in patients with cardiac syndrome X (CSX) by speckle tracking echocardiography (STE). Background: Cardiac syndrome X is a triad of angina pectoris, positive stress test for myocardial ischemia and angiographically free coronary arteries. Two dimensional speckle tracking?echocardiography (2D-STE) provides a more sensitive method for evaluation of global and segmental LV function than conventional two dimensional echocardiographic parameters. Subjects and Methods: Seventy patients proved to have CSX and 20 healthy control volunteers were included with a mean age of 49.43 ± 5.92 vs. 49.40 ±6.27 years respectively with no difference regarding sex for both patients and controls. Patients with hypertension, diabetes mellitus, valvular heart disease, cardiomyopathies, inflammatory diseases, myocarditis and arrhythmias were excluded. All included individuals were subjected to complete conventional echocardiographic assessment and left ventricular global and segmental mechanical function was assessed using 2D based strain and strain rate (longitudinal, radial and circumferential) imaging. Results: There was no statistically significant difference in LV conventional echo parameters between patients and controls. However, global mean longitudinal strain was significantly lower in patients than controls (-15.05 ± 3.28 vs. -20.22 ± 2.49;p 0.001). For radial and circumferential strain stain, there was no significant changes between patients vs. controls (29.75 ± 18.26 vs. 28.09 ± 15.48;p = 0.74) and (-19.88 ± 8.63 vs. -21.93 ± 5.69;p 0.05) respectively. Conclusion: In spite of normal conventional echo parameters among patients and controls, LV longitudinal strain and strain rate by 2D speckle tracking imaging were lower in the patients denoting subclinical left ventricular mechanical dysfunction in patients with CSX. 展开更多
关键词 Cardiac Syndrome X left ventricular SYSTOLIC and DIASTOLIC function 2D-Speckle Tracking STRAIN and STRAIN Rate imaging
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Value of two-dimensional speckle tracking imaging in quantitative assessment of left ventricular function in patients with OSAS
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作者 Guo-Ping Xie Qing-Shan Lin Chao Yu 《Journal of Hainan Medical University》 2019年第10期75-78,共4页
Objective: To research the clinical application of two-dimensional speckle tracking imaging (2D-STI) in quantitative assessment of left ventricular function in patients with obstructive sleep apnea-hypopnea syndrome (... Objective: To research the clinical application of two-dimensional speckle tracking imaging (2D-STI) in quantitative assessment of left ventricular function in patients with obstructive sleep apnea-hypopnea syndrome (OSAS). Method: From July 2016 to December 2018, 86 patients with OSAS were selected as OSAS group. According to sleep apnea hypopnea index (AHI), they were divided into mild OSAS group (24 cases), moderate OSAS group (29 cases) and severe OSAS group (33 cases). Another 50 healthy volunteers who underwent physical examination in our hospital during the same period were selected as the control group. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The results of routine echocardiography and left ventricular global strain parameters of the OSAS group, the control group and the OSAS patients with different severity were compared and analyzed. Result: There were no significant differences in the levels of left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDd), left ventricular end systolic diameter (LVESd) between the two groups and OSAS patients with different severity (P>0.05). The levels of IVST, LVPW and LVMI in the OSAS group were significantly higher than those in the control group, the levels of end-diastolic interventricular septal thickness (IVS), left ventricular posterior wall thickness (LVPW), left ventricular mass index (LVMI) in the severe OSAS group were significantly higher than those in the mild and moderate OSAS group, and the levels of IVST, LVPW and LVMI in the moderate OSAS group were significantly higher than those in the mild OSAS group, there were significant differences between groups (P<0.05). The levels of GLS, GRS and GCS in the OSAS group were significantly lower than those in the control group (P<0.05). GLS, GRS and GCS levels in the severe OSAS group were significantly lower than those in the mild OSAS group and the moderate OSAS group, while the levels of global longitudinal strain (GLS), global radial strain (GRS) and global circumferential strain (GCS) in the moderate OSAS group were significantly lower than those in the mild OSAS group (P<0.05). Conclusion: The left ventricular systolic function of OSAS patients is obviously impaired. Left ventricular function in OSAS patients can be assessed timely and accurately by two-dimensional speckle tracking imaging. 展开更多
关键词 OBSTRUCTIVE sleep APNEA HYPOPNEA syndrome ECHOCARDIOGRAPHY left ventricular global strain parameters Two-dimensional speckle tracking imaging left ventricular function
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Quantification of Regional Left Ventricular Systolic Dysfunction in Patients With Coronary Artery Disease by Strain Rate Imaging
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作者 Qiong1 Qiu, Li Yang, Jingfeng Wang Department of Cardiology, The Second Affiliated Hospital, Sun Yat-sen University, Guangzhou 510120, China 《South China Journal of Cardiology》 CAS 2007年第3期166-170,共5页
Objectives To detect and compare the systolic strain rate (SR) and strain in the infarct and ischemic myocardium by strain rate imaging (SRI), in order to explore the clinical value of SRI in evaluating regional left ... Objectives To detect and compare the systolic strain rate (SR) and strain in the infarct and ischemic myocardium by strain rate imaging (SRI), in order to explore the clinical value of SRI in evaluating regional left ventricular systolic dysfunction. Methods Patients with coronary artery disease were divided into angina pectoris (11 cases) and myocardial infarction (21 cases) groups. Twenty age-matched normal subjects served as the control group. Septal, lateral, anterior, inferior, anteroseptal and posterior walls of the left ventricle were respectively scanned using color tissue Doppler imaging (TDI). Then SR and strain curves were derived from TDI for basal, middle and apical segments of each wall. SRI parameters were: Systolic SR (SRsys), systolic strain (εsys) and maximum strain (εmax). Results Compared with normal segments, SRsys, εsys and εmax decreased significantly in the infarct and ischemic segments (P<0.01). Compared with ischemic segments, SRsys, εsys and εmax decreased significantly in the infarct segments (P<0.05). Conclusions SRsys, εsys and εmax measured by SRI can be used to quantitatively analyze regional left ventricular systolic dysfunction in patients with coronary artery disease, and aid in differentiating infarct from ischemic myocardium. 展开更多
关键词 strain rate imaging ECHOCARDIOGRAPHY coronary artery disease left ventricular systolic function
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Value of Quantitative Tissue Velocity Imaging in the Detection of Regional Myocardial Function in Dogs with Acute Subendocardial Ischemia 被引量:6
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作者 张清阳 邓又斌 +4 位作者 刘娅妮 杨好意 刘冰冰 申屠伟惠 黎鹏 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2008年第6期727-731,共5页
This study evaluated the application of quantitative tissue velocity imaging (QTVI) in assessing regional myocardial systolic and diastolic functions in dogs with acute subendocardial ischemia. Animal models of sube... This study evaluated the application of quantitative tissue velocity imaging (QTVI) in assessing regional myocardial systolic and diastolic functions in dogs with acute subendocardial ischemia. Animal models of subendocardial ischemia were established by injecting microspheres (about 300 μm in diameter) into the proximal end of left circumflex coronary artery in 11 hybrid dogs through cannulation. Before and after embolization, two-dimensional echocardiography, QTVI and real-time myocardial contrast echocardiography (RT-MCE) via intravenous infusion of self-made microbubbles,were performed, respectively. The systolic segmental wall thickening and subendocardial myocardial longitudinal velocities of risk segments before and after embolization were compared by using paired t analysis. The regional myocardial video intensity versus contrast time could be fitted to an exponential function: y=A·(1-exp-β·t), in which the product of A and β provides a measure of myocardial blood flow. RT-MCE showed that subendocardial normalized A·β was decreased markedly from 0.99±0.19 to 0.35±0.11 (P〈0.05) in 28 left ventricular (LV) myocardial segments after embolization, including 6 basal and 9 middle segments of lateral wall (LW), 8 middle segments of posterior wall (PW) and 5 middle segments of inferior wall (IW). However, there was no statistically significant difference in subepicardial layer before and after embolization. Accordingly, the ratio of A·β of subendocardial myocardium to subepicardial myocardium in these segments was significantly decreased from 1.10±0.10 to 0.31±0.07 (P〈0.05). Although the systolic wall thickening did not change 5 min after the embolization in these ischemic segments (29%±3% vs 31%±5%, P〉0.05), the longitudinal peak systolic velocities (Vs) and early-diastolic peak velocities (Ve) recorded by QTVI were declined significantly (P〈0.05). Moreover, the subendocardial velocity curves during isovolumic relaxation predominantly showed positive waves, whereas they mainly showed negative waves before the embolization. This study demonstrates that QTVI can more sensitively and accurately detect abnormal regional myocardial function and post-systolic systole caused by acute subendocardial ischemia. 展开更多
关键词 ULTRASONOGRAPHY subendocardial ischemia left ventricular function tissue velocity imaging
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An Overview of the Consequences of Distal Coronary Microembolization on Left Ventricular Function, Perfusion and Viability 被引量:1
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作者 Maythem Saeed 《International Journal of Clinical Medicine》 2011年第1期40-50,共11页
Annually, an estimated 1,285,000 in-patient angioplasty procedures, 1,471,000 inpatient diagnostic cardiac catheteri-zations and 68,000 inpatient defibrillator implantations are performed. The direct and indirect cost... Annually, an estimated 1,285,000 in-patient angioplasty procedures, 1,471,000 inpatient diagnostic cardiac catheteri-zations and 68,000 inpatient defibrillator implantations are performed. The direct and indirect cost of cardiovascular diseases for 2007 is approximately $431.8 billion. The occurrence of plaque rupture with subsequent microemboli of atherosclerotic and thrombolytic debris into small coronary vessels has been confirmed. Microinfarction results from microemboli that are shed following coronary interventions. The aims of this review are to: 1) detect heterogeneous microinfarction using viability imaging, 2) characterize the consequences of distal coronary microembolization on left ventricle function and perfusion and 3) illustrate the progress of non-invasive imaging modalities in assessing distal coronary microembolization. 展开更多
关键词 DISTAL CORONARY Microemblolization Microinfarct left ventricular function Cardiac imaging
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Accuracy of left ventricular function from electrocardiographygated myocardial perfusion SPECT by MyoMetrix in Chinese
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作者 Yang-Chun Chen Ruo-Zhu Dai +3 位作者 Ke-Lian Zhang Yong-Da Dong Hui-Lin Zhuo Qing-Mu Wang 《Nuclear Science and Techniques》 SCIE CAS CSCD 2017年第1期36-41,共6页
This work was to determine threshold values for accurate measurements of left ventricular end-diastolic volume(EDV),end-systolic volume(ESV),and ejection fraction(EF) from electrocardiography-gated myocardial perfusio... This work was to determine threshold values for accurate measurements of left ventricular end-diastolic volume(EDV),end-systolic volume(ESV),and ejection fraction(EF) from electrocardiography-gated myocardial perfusion imaging(MPI) in Chinese,and these data were compared with those of echocardiography.A total of 110 patients with definite or suspected coronary artery disease were referred for both gated MPI and echocardiography within 1 week.The EDV,ESV,and EF automatically measured by MyoMetrix and echocardiography were analyzed using Bland-Altman plot correlation and paired t test.The results showed that these parameters quantified by MyoMetrix software were correlated,moderately to highly,with those on echocardiography(ρ,r ≥0.75,P<0.01).However,the EF was not significantly correlated,with post-exercise MPI ESV of <15 mL or resting MPI ESV of <20 mL.At or above this ESV value,EF was underestimated by MyoMetrix(t≥ 4.60,P<0.01).In a word,a small ESV was underestimated by MyoMetrix,which could lead to EF overestimation.On the contrary,a normal or large ESV was overestimated by MyoMetrix,which led to EF underestimation. 展开更多
关键词 MYOCARDIAL PERFUSION imaging left ventricular function Software
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Systematic Evaluation of Current Possibilities to Determine Left Ventricular Volumes by Echocardiography in Patients after Myocardial Infarction
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作者 Stephan Stoebe Adrienn Tarr +2 位作者 Tudor Trache Jens-Gerrit Kluge Dietrich Pfeiffer 《Open Journal of Medical Imaging》 2012年第2期68-75,共8页
Purpose: The aim of the present study was to evaluate the diagnostic accuracy for quantification of left ventricular (LV) volumes and LV ejection fraction (LVEF) with current echocardiographic methods of planimetry fo... Purpose: The aim of the present study was to evaluate the diagnostic accuracy for quantification of left ventricular (LV) volumes and LV ejection fraction (LVEF) with current echocardiographic methods of planimetry for analysis of LV remodeling after myocardial infarction in daily clinical routine. Methods: 26 patients were investigated directly after interventional therapy at hospital pre-discharge and at 6 month follow-up. Standardized 2D transthoracic native and contrast echocardiography were performed in all patients. Due to methodological aspects the results of LV volumes and LVEF using native echocardiography were compared to the results of LV opacification (LVO) imaging for analysis in mono-, bi- and triplane data sets using the Simpson’s rule. In addition corresponding multidimensional data sets were analyzed. Results: The assessment of LV volumes and LVEF is more accurate with contrast echocardiography. The comparison of LV volumes and LVEF shows significant increases using contrast echocardiography (p < 0.001). Larger left ventricular end-diastolic volumes (LVEDV) are measured at follow up (p < 0.05). Significant differences (p < 0.001) are found for the determination of LVEDV and LVEF relating to apical mono-, bi-, tri- and multiplane data sets. Standard deviations of the triplane approach, however, are significantly lower than using other modalities. Conclusion: Depending on the localization of the myocardial infarction LV volumes and LVEF are less reliably evaluated using the mono- or biplane approach. According to standardization and simultaneous acquisition of all LV wall segments the triplane approach is currently the best approach to determine LV systolic function. In addition, contrast echocardiography is indicated to improve endocardial border delineation in patients using the triplane or multiplane approach. To our knowledge the present study is the first systematic evaluation of all current possibilities for determination of LV volumes and LVEF by native and contrast echocardiography. 展开更多
关键词 Contrast ECHOCARDIOGRAPHY left ventricular SYSTOLIC function left ventricular VOLUMES Remodeling Myocardial INFARCTION LVO imaging
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实时三维超声心动图结合二维斑点追踪技术评价高龄孕晚期孕妇左心室收缩功能 被引量:2
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作者 薛洁 王慧敏 +3 位作者 徐丽华 郑丽丽 姜静 王志斌 《中国临床医学影像杂志》 CAS CSCD 北大核心 2024年第1期41-45,共5页
目的:运用实时三维超声心动图(RT-3DE)和二维斑点追踪技术(2D-STI)评估高龄孕晚期孕妇左心室收缩功能。方法:选取20~45岁孕晚期孕妇为研究对象,另纳入年龄匹配的健康查体女性102例作为对照组。对所有纳入对象用辛普森双平面法、2D-STI及... 目的:运用实时三维超声心动图(RT-3DE)和二维斑点追踪技术(2D-STI)评估高龄孕晚期孕妇左心室收缩功能。方法:选取20~45岁孕晚期孕妇为研究对象,另纳入年龄匹配的健康查体女性102例作为对照组。对所有纳入对象用辛普森双平面法、2D-STI及RT-3DE进行检查分析,采用t检验或Mann-Whitney U检验对比高龄孕妇与对照组受试者左室收缩功能的差异。结果:三种方法测量的左室射血分数(LVEF)组间均无统计学差异(P>0.05)。高龄孕妇较高龄对照受试者左室LSapi减低,Tmsv-16-SD%及Tmsv-16-Dif%增高(P<0.05),高龄孕妇较适龄孕妇LSbas增加(P<0.05)。结论:高龄孕妇孕晚期LVEF处于正常水平,但可能已经存在左室壁局部纵向应变减低和心肌运动同步性减低,RT-3DE及2D-STI均可早期评价左室收缩功能改变,提示临床给予早期干预。 展开更多
关键词 心室功能 孕妇 超声心动描记术 多普勒
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超声左心室自动功能成像评估胰岛素泵输注治疗2型糖尿病合并肺结核左心室功能
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作者 杨丽萍 李小卉 +2 位作者 张晶 赵艳君 杨爱琼 《中国医学装备》 2024年第7期82-86,共5页
目的:探索超声左心室自动功能成像(AFI)评估胰岛素泵输注治疗2型糖尿病(T2DM)合并肺结核左心室功能的效果。方法:选取2020年12月至2022年10月新疆医科大学第一附属医院收治的108例T2DM合并肺结核老年患者纳入观察组,选取同期在本院接受... 目的:探索超声左心室自动功能成像(AFI)评估胰岛素泵输注治疗2型糖尿病(T2DM)合并肺结核左心室功能的效果。方法:选取2020年12月至2022年10月新疆医科大学第一附属医院收治的108例T2DM合并肺结核老年患者纳入观察组,选取同期在本院接受体检的90名健康体检者纳入健康对照组。观察组接受胰岛素泵的输注治疗,并于治疗前后采用超声左心室AFI评估左心室功能参数;健康对照组检查左心室指标及血糖指标。对比两组的临床指标以及超声参数上的差异性。结果:观察组治疗后与治疗前比较收缩压与空腹血糖水平均较低;观察组治疗后与治疗前分别与健康对照组相比长轴方向的全球纵向应变(GLPS-LAX)、四腔心切面的全球纵向应变(GLPS-A4C)及平均全球纵向应变(GLPS-AVG)比较均有所降低;观察组治疗后与治疗前相比GLPS-LAX、GLPS-AVG较高,差异有统计学意义(t=2.846、4.926,P<0.05)。结论:T2DM合并肺结核患者在经过胰岛素泵注射治疗后,通过采用超声左心室AFI对患者的左心室功能进行评估时发现,其左心室功能获得有效改善,采用超声左心室AFI评估T2DM合并肺结核左心室功能具有重要的临床意义。 展开更多
关键词 超声左心室自动功能成像(AFI) 胰岛素泵 2型糖尿病(T2DM) 肺结核 左心室功能
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TMAD评价保留射血分数无症状SAS病人左室功能受损及预后
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作者 任永凤 陆静 +3 位作者 李娜娜 王效军 李琦 王洲 《蚌埠医学院学报》 CAS 2024年第5期633-636,640,共5页
目的:探讨组织追踪二尖瓣环位移(TMAD)技术评价保留射血分数无症状重度主动脉瓣狭窄(SAS)病人左室纵向运动功能及其对预后的预测价值。方法:入选60例保留射血分数无症状SAS病人,依据随访结果分成2组,其中有心血管相关事件定义为A组(21... 目的:探讨组织追踪二尖瓣环位移(TMAD)技术评价保留射血分数无症状重度主动脉瓣狭窄(SAS)病人左室纵向运动功能及其对预后的预测价值。方法:入选60例保留射血分数无症状SAS病人,依据随访结果分成2组,其中有心血管相关事件定义为A组(21例),未发生心血管相关事件定义为B组(39例)。收集研究对象临床资料,所有入选病人检查后进行24个月随访。采集病人连续4个心动周期心尖四腔、三腔及两腔切面动态图像,双平面辛普森法测量左室射血分数(LVEF)。利用二维斑点追踪超声心动图技术获取左室整体纵向应变(LVGLS),四腔心获取间隔与侧壁瓣环连线中点的纵向平均位移(TMAD Midpt),设备并可自动获取TMAD占舒张末期左室长径的百分比(TMAD Midpt%)。比较2组上述各参数的差异,并分析TMAD Midpt%预测SAS病人发生心脏相关事件的价值。结果:60例病人中A组TMAD Midpt%及LVGLS低于B组(P<0.01),2组LVEF差异无统计学意义(P>0.05);A组病人心肌质量指数(MI)与B型脑钠肽(BNP)明显高于B组(P<0.01),2组其他临床资料及超声心动图参数比较差异均无统计学意义(P>0.05)。60例病人TMAD Midpt%随着LVGLS的降低而降低,两者呈正相关关系(r=0.696,P<0.01)。ROC曲线分析显示,TMAD Midpt%预测心脏事件与LVGLS具有相当的价值,曲线下面积分别为0.897、0.901(P<0.01)。结论:TMAD Midpt%在预测心脏事件发生方面与LVGLS具有相同的价值,而技术简便,可以快速地评估左室射血分数保留的无症状SAS病人左室功能损害及预测心脏事件的发生,值得临床推广应用。 展开更多
关键词 主动脉瓣狭窄 组织追踪二尖瓣环位移 左室收缩功能
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组织瓣环运动位移评价心室肥厚患者左室收缩功能
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作者 贾玄慧 亢春苗 +2 位作者 沈亚梅 马盼盼 朱媛 《临床医学研究与实践》 2024年第10期85-89,共5页
目的探讨组织瓣环运动位移(TMAD)自动追踪技术定量评价心室肥厚患者左室收缩功能的应用价值。方法纳入60例心室肥厚患者,原发性高血压亚组30例,尿毒症亚组30例,纳入35例健康体检者作为对照组。应用二维斑点追踪技术自动获取心尖四腔心... 目的探讨组织瓣环运动位移(TMAD)自动追踪技术定量评价心室肥厚患者左室收缩功能的应用价值。方法纳入60例心室肥厚患者,原发性高血压亚组30例,尿毒症亚组30例,纳入35例健康体检者作为对照组。应用二维斑点追踪技术自动获取心尖四腔心切面、心尖两腔心切面二尖瓣环四个位点TMAD值、左心室整体纵向应变(LVGLS)及左室整体圆周应变(LVGCS),应用Bland-Altman法检验TMAD参数一致性及绘制受试者工作特性(ROC)曲线评价TMAD参数的诊断效能。结果原发性高血压亚组和尿毒症亚组的收缩压(SBP)、舒张压(DBP)明显高于对照组(P<0.05);尿毒症亚组的心率(HR)高于原发性高血压亚组及对照组(P<0.05)。尿毒症亚组的TMAD参数及应变参数均明显低于对照组(P<0.05)。原发性高血压亚组的LVGLS、T-AP4sep、T-AP4mid%、T-AP2int、T-AP2ant及T-AP2mid%低于对照组(P<0.05)。ROC曲线结果显示,TMAD各参数对心室肥厚患者左室收缩功能降低具有中等预测价值。结论TMAD可以定量评价心室肥厚患者的左室收缩功能,且可重复性好。 展开更多
关键词 组织瓣环运动位移 心室肥厚 尿毒症 原发性高血压 左室收缩功能 斑点追踪技术
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无节段性室壁运动异常冠心病患者PCI术后左室功能的效果评价
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作者 薛娜 刘昕 +1 位作者 李晓青 屠英暄 《心脏杂志》 CAS 2024年第5期516-520,共5页
目的应用常规超声心动图及三维应变定量评价无节段性室壁运动异常冠心病患者经皮冠状动脉介入(percutaneous coronary intervention,PCI)治疗前后左室收缩和舒张功能的变化,探讨PCI手术及支架置入数目对冠心病患者的疗效。方法选择112... 目的应用常规超声心动图及三维应变定量评价无节段性室壁运动异常冠心病患者经皮冠状动脉介入(percutaneous coronary intervention,PCI)治疗前后左室收缩和舒张功能的变化,探讨PCI手术及支架置入数目对冠心病患者的疗效。方法选择112例无节段性室壁运动异常的冠心病患者,分别于PCI术前3 d及术后6个月行超声心动图检查,根据支架置入数目分三组,即1枚支架组(n=55)、2枚支架组(n=35)和3枚支架组(n=22),收集其基本临床资料、常规超声心动图数据及三维应变数据,并计算出相应方向的应变显像舒张功能指数(SI-DI)分析其变化。结果PCI术前术后两组数据比较,PCI术前pro-BNP数值高于术后值(P<0.05),收缩压、舒张压、血糖、血脂、体质量指数(BMI)等项目术前术后数据差异无统计学意义。PCI术前术后两组常规超声参数比较,两组间E、e′、EDV、ESV、及E/e′术后较术前升高,两组间LVEF、SV比较,术后较术前降低,但其差异均无统计学意义。PCI术前术后两组三维参数比较,PCI术前术后两组GLS、GRS、GAS、GCS、L-SI-DI、A-SI-DI、C-SI-DI、RSI-DI差异有统计学意义(均P<0.01),PCI术后明显高于术前。不同支架数3组间三维参数比较,PCI术前三组各方向应变及相应SI-DI差异无统计学意义。PCI术后随着支架数目的增加,GLS、GAS、GCS、GRS、L-SI-DI、ASI-DI、C-SI-DI及R-SI-DI呈减低趋势。2枚支架组GCS、L-SI-DI均低于1枚支架组(均P<0.05),3枚支架组GLS、GCS、GAS、L-SI-DI、C-SI-DI、A-SI-DI均低于1枚支架组(均P<0.05),3枚支架组GLS、GCS、GAS、L-SIDI、C-SI-DI低于2枚支架组(均P<0.05);三组间GRS和R-SI-DI差异无统计学意义。不同数目支架组各参数术后较术前呈升高趋势,1枚支架组GLS、GAS、GCS、GRS、L-SI-DI、A-SI-DI、C-SI-DI高于术前(均P<0.05),2枚支架组GAS高于术前(P<0.05),3枚支架组手术前后差异无统计学意义。结论三维应变优于常规超声心动图,可以定量评价PCI术后左室收缩和舒张功能改变,评估冠心病患者PCI治疗效果;支架置入数目与PCI术后左室功能恢复情况有关。 展开更多
关键词 冠心病 左室功能 实时三维斑点追踪 经皮冠状动脉介入治疗
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