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Neuro-Modulation in Dorsal Premotor Cortex Facilitates Human Multi-Task Ability
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作者 Yusuke Suzuki Eiichi Naito 《Journal of Behavioral and Brain Science》 2012年第3期372-379,共8页
Humans are limited in their ability to perform multiple cognitive-motor tasks in parallel. In eight participants, we examined whether transcranial direct current stimulation (tDCS) to dorsal premotor cortex (PMD) coul... Humans are limited in their ability to perform multiple cognitive-motor tasks in parallel. In eight participants, we examined whether transcranial direct current stimulation (tDCS) to dorsal premotor cortex (PMD) could attenuate a delay of reaction time (RT) while the participants responded to two visual stimuli presented in temporally close succession. We provided anodal, cathodal, or sham tDCS while the participants performed a task requiring two choice responses or a control task requiring two fixed responses. When the interval between the two stimuli was shorter, the RTs were delayed in both tasks, but anodal tDCS shortened them only in the former task, probably by promoting the response selection function of PMD. Non-invasive neuro-modulation to the brain can boost human ability to multi-task. 展开更多
关键词 TRANSCRANIAL Direct Current Stimulation (tDCS) PSYCHOLOGICAL Refractory Period (PRP) dorsal premotor cortex (pmd) Response Selection
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猕猴F2及F4区皮层神经元在空间有序运动中的放电活动
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作者 沈丽敏 陈郁初 《生理学报》 CAS CSCD 北大核心 2000年第2期109-114,共6页
用胞外单位放电记录的方法 ,研究了猕猴在执行记忆引导的空间有序运动 (MSS)时 ,大脑皮层弓形沟距背侧F2及腹侧F4区的放电活动。对于以绿色为暗示信号的MSS G任务 ,在暗示期 ,F2 ( 78 2 % )比F4区( 41 5 % )有更多的细胞发生放电变化 ( ... 用胞外单位放电记录的方法 ,研究了猕猴在执行记忆引导的空间有序运动 (MSS)时 ,大脑皮层弓形沟距背侧F2及腹侧F4区的放电活动。对于以绿色为暗示信号的MSS G任务 ,在暗示期 ,F2 ( 78 2 % )比F4区( 41 5 % )有更多的细胞发生放电变化 ( χ2 =15 2 ,P <0 0 0 5 ) ;在图形期 ,F4( 6 7 9% )比F2区 ( 45 4% )有更多的细胞发生放电变化 ( χ2 =5 5 ,P <0 0 5 ) ;在触摸反应期 ,F4发生放电改变的细胞数 ( 75 5 % )显著地多于F2区 ( 2 7 3% )( χ2 =2 5 1,P <0 0 0 5 )。对于以红色为暗示信号的MSS R任务 ,在暗示期 ,F2发生放电改变的细胞数 ( 6 9 5 % )多于F4区 ( 44 6 % ) ( χ2 =7 2 ,P <0 0 1) ;在图形期 ,F4发生放电改变的细胞数 ( 6 6 1% )显著地多于F2区 ( 2 5 4% )( χ2 =19 2 ,P <0 0 0 5 ) ;在触摸反应期 ,F4( 6 7 8% )比F2区 ( 44 1% )有更多的细胞发生放电变化 ( χ2 =6 6 ,P <0 0 5 )。可见 ,无论是MSS G任务还是MSS R任务 ,F2区比F4区有更多细胞对MSS任务中的暗示信号发生放电变化 ,而F4区比F2区细胞更易在图形期和触摸反应期发生放电变化。结果提示 ,猕猴弓形沟距周围F2和F4区细胞均参与MSS任务 。 展开更多
关键词 细胞活动 猕猴 皮层神经元 放电活动
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