Background and Aims: This study examined the stress levels, the stressors and biomarker such as Alpha (α)-Amylase enzyme which is secreted under distress conditions. The aim was to determine the relationship between ...Background and Aims: This study examined the stress levels, the stressors and biomarker such as Alpha (α)-Amylase enzyme which is secreted under distress conditions. The aim was to determine the relationship between these three variables. Methods: The study respondents were made up of cancer outpatients from 3 hospitals namely the Hospital Kuala Lumpur, Seberang Jaya and Johor Baru, Pantai Ipoh and Putrajaya. The Personal Stress Inventory (PSI) questionnaire was used to identify stressors, while the Hospital Anxiety and Depression Scale (HADS) were used to determine the psychological distress levels. The Salimentary Oral Swab (SOS) Technique was used to collect the saliva and then the Salivary α-Amylase Assay Kit was used to analyse for α amylase. Results: The majority of respondents were stressed due to their sensitive emotion and nervousness in their daily lives (68.7%), they had poor memory and short attention spans of carrying out job tasks (67.3%) as well as they were emotionally depressed (65.3%). Their poor memory and short attention span (p = 0.037), heavy work load and poor task delivery (p = 0.008) were predictors for distress using HADS. The salivary α-amylase concentration was significantly related to the stress levels (p = 0.002). Conclusion: Breast cancer respondents with musculoskeletal system related symptoms, with heavy work load and poor task delivery, as well as had poor memory and short attention span were at higher risk of experiencing psychological distress. The salivary α-amylase which had significant relationships with psychological distress was therefore, a potential biological indicator for distress, while the musculoskeletal system related symptoms from the PSI questionnaire were predictors for distress.展开更多
Purpose: The main goal of this study is to discover the scientific evolution of Cancer-Related Symptoms in Complementary and Alternative Medicine research area, analyzing the articles indexed in the Web of Science da...Purpose: The main goal of this study is to discover the scientific evolution of Cancer-Related Symptoms in Complementary and Alternative Medicine research area, analyzing the articles indexed in the Web of Science database from 1980 to 2013.Design/Methodology/Approach: A co-word science mapping analysis is performed under a longitudinal framework(1980 to 2013). The documental corpus is divided into two subperiods,1980–2008 and 2009–2013. Thus, the performance and impact rates, and conceptual evolution of the research field are shown.Findings: According to the results, the co-word analysis allows us to identify 12 main thematic areas in this emerging research field: anxiety, survivors and palliative care,meditation, treatment, symptoms and cancer types, postmenopause, cancer pain, low back pain, herbal medicine, children, depression and insomnia, inflammation mediators, and lymphedema. The different research lines are identified according to the main thematic areas,centered fundamentally on anxiety and suffering prevention. The scientific community can use this information to identify where the interest is focused and make decisions in different ways.Research limitation: Several limitations can be addressed: 1) some of the Complementary and Alternative Medicine therapies may not have been included; 2) only the documents indexed in Web of Science are analyzed; and 3) the thematic areas detected could change if another dataset was considered.Practical implications: The results obtained in the present study could be considered as an evidence-based framework in which future studies could be built.Originality/value: Currently, there are no studies that show the thematic evolution of this research area.展开更多
Introduction: <span style="font-family:""><span style="font-family:Verdana;">Some somatic and psychological disorders have been associated with handgrip strength, which is an easy,...Introduction: <span style="font-family:""><span style="font-family:Verdana;">Some somatic and psychological disorders have been associated with handgrip strength, which is an easy, inexpensive and noninvasive method for assessment of muscle strength. We conducted a cross-sectional </span><span style="font-family:Verdana;">study to clarify the relationship of handgrip strength and menstruation-related </span><span style="font-family:Verdana;">symptoms. </span><b><span style="font-family:Verdana;">Material and Methods:</span></b><span style="font-family:Verdana;"> Handgrip strength was measured and a self-administered questionnaire was performed in female university students in Japan. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">Handgrip strength did not significantly differ among the menstrual phases. The mean handgrip strength level (n = 260) was 26.0 ± 3.9 kg. We divided the subjects into three groups according to the handgrip strength level. Handgrip strength was associated with degrees of depression and anxiety during menstruation.</span><b><span style="font-family:Verdana;"> Conclusion: </span></b><span style="font-family:Verdana;">This can be used as fundamental data in further clarifying the relationship between muscle strength and menstruation-related symptoms.</span></span>展开更多
Objective: To evaluate and compare the safety and efficacy of Solifenacin, Tamsulosin, and Tadalafil in treating ureteral stent related symptoms (SRS) in patients with indwelling Double-J ureteral stents. Materials an...Objective: To evaluate and compare the safety and efficacy of Solifenacin, Tamsulosin, and Tadalafil in treating ureteral stent related symptoms (SRS) in patients with indwelling Double-J ureteral stents. Materials and Methods: A prospective randomized controlled study was conducted on 146 consecutive patients in the department of urology, Government Stanley Medical College & Hospital, Chennai, Tamilnadu, India between Sept 2017-March 2019, with SRS after taking informed consent and confirming DJ Stent position by X-ray KUB post-operatively. Patients were randomized into 4 groups: Group A (Placebo), Group B (Solifenacin 5 mg), and Group B (Tamsulosin 0.4 mg) and group D (Tadalafil 5 mg) at end of 1st week till the removal of DJ stent at end of 3 weeks. All patients were assessed for bothersome lower urinary tract symptoms (LUTS) using the validated Ureteral Stent Symptom Questionnaire (USSQ) at 1st week and 3 weeks after the starting of medications. Appropriate statistical analysis as carried out and the level of significance was set at P Results: LUTS, general health, and work performance improved with Solifenacin, Tamsulosin and Tadalafil and all the three were comparable in relieving urinary symptoms. Tadalafil was better at relieving body pain, additional problems and sexual problems better than Tamsulosin. Tadalafil showed comparable improvement in LUTS, better sexual health and decreased body pain compared to solifenacin, whereas the latter had better general health, additional problems & work performance scores. Conclusion: Solifenacin is more effective than Tamsulosin in alleviating LUTS associated with SRS and both show a distinctive advantage over placebo. PDE inhibitor Tadalafil can also be tried for SRS and is as effective as antimuscarinics and α-blockers in relieving urinary symptoms and is more efficacious in relieving sexual symptoms and body pain.展开更多
Smartphones use for a long period of time can cause health problems including physical condition, psychological condition and sleeping status. In addition, smartphones use may affect menstruation related symptoms. Thi...Smartphones use for a long period of time can cause health problems including physical condition, psychological condition and sleeping status. In addition, smartphones use may affect menstruation related symptoms. This study was conducted using a self-administered questionnaire between June and November in 2016 to clarify the differences in physical and psychological condition, sleeping status and menstruation-related symptoms before and after starting to use smartphones in female university students in Japan. We recruited 273 female nursing students and the response rate was 95.2%. We found significant changes after starting to use smartphones regarding eyestrain (p < 0.001), posture (p = 0.002), stiffness of neck, back and shoulders (p < 0.001), level of outdoor activity (p < 0.001), difficulty concentrating (p < 0.001), lack of motivation (p < 0.001), and sensitivity to stress (p = 0.005). Moreover, we also found that fatigue before menstruation and headache/low back pain during menstruation were higher after starting to use smartphones. The proportions of students with irritability and depressive feeling as emotional premenstrual symptoms appeared higher after starting to use smartphones. These results imply that young women should refrain from using smartphones if they have visual display terminal-related symptoms, disturbance of sleep pattern and menstruation-related symptoms before and during menstruation.展开更多
Sensitivity to cold, which is a popular symptom in Japanese women, is associated with various symptoms such as shoulder stiffness and general fatigue. However, an association of sensitivity to cold with muscle strengt...Sensitivity to cold, which is a popular symptom in Japanese women, is associated with various symptoms such as shoulder stiffness and general fatigue. However, an association of sensitivity to cold with muscle strength has not been reported. The aim of the study was to clarify the associations of sensitivity to cold with handgrip strength and with menstruation-related symptoms in female university students in Japan. We recruited 278 female university students in Japan. Sensitivity to cold and menstruation-related symptoms including physical and psychological symptoms were assessed by using a self-administered questionnaire that we designed. Handgrip strength was measured by using a handgrip strength dynamometer. We received responses from 269 students. The prevalence rate of sensitivity to cold in the subjects was 54.3%. The students who had sensitivity to cold had a lower handgrip strength level (25.5 ± 3.8 kg) than did the students who did not have sensitivity to cold (26.7 ± 3.9 kg) (p = 0.017). Sensitivity to cold was associated with low body mass index. In addition, the students who had sensitivity to cold tended to have low back pain and constipation during menstruation. In conclusion, sensitivity to cold is an important symptom associated with muscle strength as well as menstruation-related symptoms for young women.展开更多
Objective:This survey was a non-intervention study,which aimed to investigate symptom burden and treatment status in cancer patient with bone metastasis,and to make out whether patients received the normative treatmen...Objective:This survey was a non-intervention study,which aimed to investigate symptom burden and treatment status in cancer patient with bone metastasis,and to make out whether patients received the normative treatment.Methods:We designed a questionnaire,the main items of which include patient's symptom burden,previous and ongoing treatment.We used it to investigate 120 patients from six different medical agencies.We examined the association between symptoms using Spearman's rank correlation.SPSS software was used to analyze data.Results:The data of one hundred one questionnaires were completed and fitted for analysis.The five most prevalent symptoms were fatigue(84.2%),unhappiness(83.2%),pain(77.2%),dry mouth(77.2%) and lack of appetite(73.3%).Three symptom clusters were identified.Cluster 1 included anxiety and unhappiness and accounted for 61.4% in all patients.Cluster 2 included pain,fatigue and constipation and accounted for 39.6% in all patients.Cluster 3 included nausea,vomiting,lack of appetite and accounted for 27.7% in all patients.Cronbach's alpha coefficient demonstrated high internal reliability in the clusters,with a coefficient ranging from 0.65 to 0.84.The proportion of patients receiving analgesic therapy,bisphosphates therapy,palliative chemotherapy and radiotherapy were 70.3%,63.4%,58.4% and 36.6% respectively.Pain in various degree was obviously alleviated(P < 0.01) after analgesic therapy.Among the surveyed patients,64 patients received bisphosphates therapy,while the administration of zoledronic acid accounted for the most large proportion.The average duration of bisphosphates administration was 5.79 months(SD = 7.43).Patients who received radiotherapy adopted multiple fractions treating mode.Conclusion:Symptom burden was common and severe in patients with bone metastasis,which often appeared as symptom cluster,and significantly affected their quality of life(QOL).The normative treatment should be strengthened to manage and control patients' symptoms and improve their QOL.The analgesic therapy was normative in patients with bone metastasis.Reasons impeding patients to receive bisphosphates were in varieties.More propaganda should be done to generalized bisphosphates therapy for patients with bone metastasis.展开更多
文摘Background and Aims: This study examined the stress levels, the stressors and biomarker such as Alpha (α)-Amylase enzyme which is secreted under distress conditions. The aim was to determine the relationship between these three variables. Methods: The study respondents were made up of cancer outpatients from 3 hospitals namely the Hospital Kuala Lumpur, Seberang Jaya and Johor Baru, Pantai Ipoh and Putrajaya. The Personal Stress Inventory (PSI) questionnaire was used to identify stressors, while the Hospital Anxiety and Depression Scale (HADS) were used to determine the psychological distress levels. The Salimentary Oral Swab (SOS) Technique was used to collect the saliva and then the Salivary α-Amylase Assay Kit was used to analyse for α amylase. Results: The majority of respondents were stressed due to their sensitive emotion and nervousness in their daily lives (68.7%), they had poor memory and short attention spans of carrying out job tasks (67.3%) as well as they were emotionally depressed (65.3%). Their poor memory and short attention span (p = 0.037), heavy work load and poor task delivery (p = 0.008) were predictors for distress using HADS. The salivary α-amylase concentration was significantly related to the stress levels (p = 0.002). Conclusion: Breast cancer respondents with musculoskeletal system related symptoms, with heavy work load and poor task delivery, as well as had poor memory and short attention span were at higher risk of experiencing psychological distress. The salivary α-amylase which had significant relationships with psychological distress was therefore, a potential biological indicator for distress, while the musculoskeletal system related symptoms from the PSI questionnaire were predictors for distress.
基金supported by the Andalusian Excellence Project TIC-5991Spanish National Project TIN2016-75850-RJ.A.Moral-Munoz held an FPU scholarship (AP2012-1789) from the Spanish Ministry of Education
文摘Purpose: The main goal of this study is to discover the scientific evolution of Cancer-Related Symptoms in Complementary and Alternative Medicine research area, analyzing the articles indexed in the Web of Science database from 1980 to 2013.Design/Methodology/Approach: A co-word science mapping analysis is performed under a longitudinal framework(1980 to 2013). The documental corpus is divided into two subperiods,1980–2008 and 2009–2013. Thus, the performance and impact rates, and conceptual evolution of the research field are shown.Findings: According to the results, the co-word analysis allows us to identify 12 main thematic areas in this emerging research field: anxiety, survivors and palliative care,meditation, treatment, symptoms and cancer types, postmenopause, cancer pain, low back pain, herbal medicine, children, depression and insomnia, inflammation mediators, and lymphedema. The different research lines are identified according to the main thematic areas,centered fundamentally on anxiety and suffering prevention. The scientific community can use this information to identify where the interest is focused and make decisions in different ways.Research limitation: Several limitations can be addressed: 1) some of the Complementary and Alternative Medicine therapies may not have been included; 2) only the documents indexed in Web of Science are analyzed; and 3) the thematic areas detected could change if another dataset was considered.Practical implications: The results obtained in the present study could be considered as an evidence-based framework in which future studies could be built.Originality/value: Currently, there are no studies that show the thematic evolution of this research area.
文摘Introduction: <span style="font-family:""><span style="font-family:Verdana;">Some somatic and psychological disorders have been associated with handgrip strength, which is an easy, inexpensive and noninvasive method for assessment of muscle strength. We conducted a cross-sectional </span><span style="font-family:Verdana;">study to clarify the relationship of handgrip strength and menstruation-related </span><span style="font-family:Verdana;">symptoms. </span><b><span style="font-family:Verdana;">Material and Methods:</span></b><span style="font-family:Verdana;"> Handgrip strength was measured and a self-administered questionnaire was performed in female university students in Japan. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">Handgrip strength did not significantly differ among the menstrual phases. The mean handgrip strength level (n = 260) was 26.0 ± 3.9 kg. We divided the subjects into three groups according to the handgrip strength level. Handgrip strength was associated with degrees of depression and anxiety during menstruation.</span><b><span style="font-family:Verdana;"> Conclusion: </span></b><span style="font-family:Verdana;">This can be used as fundamental data in further clarifying the relationship between muscle strength and menstruation-related symptoms.</span></span>
文摘Objective: To evaluate and compare the safety and efficacy of Solifenacin, Tamsulosin, and Tadalafil in treating ureteral stent related symptoms (SRS) in patients with indwelling Double-J ureteral stents. Materials and Methods: A prospective randomized controlled study was conducted on 146 consecutive patients in the department of urology, Government Stanley Medical College & Hospital, Chennai, Tamilnadu, India between Sept 2017-March 2019, with SRS after taking informed consent and confirming DJ Stent position by X-ray KUB post-operatively. Patients were randomized into 4 groups: Group A (Placebo), Group B (Solifenacin 5 mg), and Group B (Tamsulosin 0.4 mg) and group D (Tadalafil 5 mg) at end of 1st week till the removal of DJ stent at end of 3 weeks. All patients were assessed for bothersome lower urinary tract symptoms (LUTS) using the validated Ureteral Stent Symptom Questionnaire (USSQ) at 1st week and 3 weeks after the starting of medications. Appropriate statistical analysis as carried out and the level of significance was set at P Results: LUTS, general health, and work performance improved with Solifenacin, Tamsulosin and Tadalafil and all the three were comparable in relieving urinary symptoms. Tadalafil was better at relieving body pain, additional problems and sexual problems better than Tamsulosin. Tadalafil showed comparable improvement in LUTS, better sexual health and decreased body pain compared to solifenacin, whereas the latter had better general health, additional problems & work performance scores. Conclusion: Solifenacin is more effective than Tamsulosin in alleviating LUTS associated with SRS and both show a distinctive advantage over placebo. PDE inhibitor Tadalafil can also be tried for SRS and is as effective as antimuscarinics and α-blockers in relieving urinary symptoms and is more efficacious in relieving sexual symptoms and body pain.
文摘Smartphones use for a long period of time can cause health problems including physical condition, psychological condition and sleeping status. In addition, smartphones use may affect menstruation related symptoms. This study was conducted using a self-administered questionnaire between June and November in 2016 to clarify the differences in physical and psychological condition, sleeping status and menstruation-related symptoms before and after starting to use smartphones in female university students in Japan. We recruited 273 female nursing students and the response rate was 95.2%. We found significant changes after starting to use smartphones regarding eyestrain (p < 0.001), posture (p = 0.002), stiffness of neck, back and shoulders (p < 0.001), level of outdoor activity (p < 0.001), difficulty concentrating (p < 0.001), lack of motivation (p < 0.001), and sensitivity to stress (p = 0.005). Moreover, we also found that fatigue before menstruation and headache/low back pain during menstruation were higher after starting to use smartphones. The proportions of students with irritability and depressive feeling as emotional premenstrual symptoms appeared higher after starting to use smartphones. These results imply that young women should refrain from using smartphones if they have visual display terminal-related symptoms, disturbance of sleep pattern and menstruation-related symptoms before and during menstruation.
文摘Sensitivity to cold, which is a popular symptom in Japanese women, is associated with various symptoms such as shoulder stiffness and general fatigue. However, an association of sensitivity to cold with muscle strength has not been reported. The aim of the study was to clarify the associations of sensitivity to cold with handgrip strength and with menstruation-related symptoms in female university students in Japan. We recruited 278 female university students in Japan. Sensitivity to cold and menstruation-related symptoms including physical and psychological symptoms were assessed by using a self-administered questionnaire that we designed. Handgrip strength was measured by using a handgrip strength dynamometer. We received responses from 269 students. The prevalence rate of sensitivity to cold in the subjects was 54.3%. The students who had sensitivity to cold had a lower handgrip strength level (25.5 ± 3.8 kg) than did the students who did not have sensitivity to cold (26.7 ± 3.9 kg) (p = 0.017). Sensitivity to cold was associated with low body mass index. In addition, the students who had sensitivity to cold tended to have low back pain and constipation during menstruation. In conclusion, sensitivity to cold is an important symptom associated with muscle strength as well as menstruation-related symptoms for young women.
文摘Objective:This survey was a non-intervention study,which aimed to investigate symptom burden and treatment status in cancer patient with bone metastasis,and to make out whether patients received the normative treatment.Methods:We designed a questionnaire,the main items of which include patient's symptom burden,previous and ongoing treatment.We used it to investigate 120 patients from six different medical agencies.We examined the association between symptoms using Spearman's rank correlation.SPSS software was used to analyze data.Results:The data of one hundred one questionnaires were completed and fitted for analysis.The five most prevalent symptoms were fatigue(84.2%),unhappiness(83.2%),pain(77.2%),dry mouth(77.2%) and lack of appetite(73.3%).Three symptom clusters were identified.Cluster 1 included anxiety and unhappiness and accounted for 61.4% in all patients.Cluster 2 included pain,fatigue and constipation and accounted for 39.6% in all patients.Cluster 3 included nausea,vomiting,lack of appetite and accounted for 27.7% in all patients.Cronbach's alpha coefficient demonstrated high internal reliability in the clusters,with a coefficient ranging from 0.65 to 0.84.The proportion of patients receiving analgesic therapy,bisphosphates therapy,palliative chemotherapy and radiotherapy were 70.3%,63.4%,58.4% and 36.6% respectively.Pain in various degree was obviously alleviated(P < 0.01) after analgesic therapy.Among the surveyed patients,64 patients received bisphosphates therapy,while the administration of zoledronic acid accounted for the most large proportion.The average duration of bisphosphates administration was 5.79 months(SD = 7.43).Patients who received radiotherapy adopted multiple fractions treating mode.Conclusion:Symptom burden was common and severe in patients with bone metastasis,which often appeared as symptom cluster,and significantly affected their quality of life(QOL).The normative treatment should be strengthened to manage and control patients' symptoms and improve their QOL.The analgesic therapy was normative in patients with bone metastasis.Reasons impeding patients to receive bisphosphates were in varieties.More propaganda should be done to generalized bisphosphates therapy for patients with bone metastasis.